The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 8, 2006, Pages 2588-2593

  Kapetanaki, Maria G ^a   Guerrero Santoro, Jennifer ^a   Bisi, Dawn C ^a,b   Hsieh, Ching L ^a   Rapić Otrin, Vesna ^a   Levine, Arthur S ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b DUQUESNE UNIVERSITY   (United States)

Author keywords

E3 ubiquitin ligase; Monoubiquitinated histone H2A; Nucleotide excision repair

Indexed keywords

CULLIN; DDB1 CUL4A UBIQUITIN PROTEIN LIGASE 3; DNA; DNA BINDING PROTEIN; HISTONE H2A; IMMUNOGLOBULIN Y; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CUL4A PROTEIN, HUMAN; DDB1 PROTEIN, HUMAN; DDB2 PROTEIN, HUMAN; HISTONE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA DAMAGE; DNA PROTEIN COMPLEX; DNA REPAIR; ENZYME DEFICIENCY; EXCISION REPAIR; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LYMPHOBLASTOID CELL; PRIORITY JOURNAL; SKIN CANCER; SKIN CARCINOGENESIS; UBIQUITINATION; ULTRAVIOLET IRRADIATION; XERODERMA PIGMENTOSUM; CELL CULTURE; CHEMISTRY; CHROMATIN; ENZYMOLOGY; GENETICS; METABOLISM; MUTATION; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

CHROMATIN; CULLIN PROTEINS; DNA; DNA DAMAGE; DNA-BINDING PROTEINS; HISTONES; HUMANS; MUTATION; TUMOR CELLS, CULTURED; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM;

EID: 33644536070     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0511160103     Document Type: Article

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