Gold (I) N-heterocyclic carbene complex inhibits mouse melanoma growth by p53 upregulation

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Nandy, Abhishek ^a   Dey, Sumit K ^a   Das, Sujata ^a   Munda, Rudra N ^b   Dinda, Joydev ^c   Saha, Krishna D ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b Maharaja Sriram Chandra Bhanja Deo University   (India)

^c ITM UNIVERSITY   (India)

Author keywords

Apoptosis; Gold (I) N heterocyclic carbene complex; Growth inhibition; Melanoma; Tumor

Indexed keywords

ANNEXIN; CARBENE; CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; GELATINASE B; GOLD COMPLEX; PHOSPHATIDYLSERINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P50; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SYNAPTOTAGMIN I; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DNA FRAGMENTATION; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; MELANOMA; MELANOMA B16; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SURVIVAL RATE; TUMOR VOLUME; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GOLD COMPOUNDS; HCT116 CELLS; HEP G2 CELLS; HETEROCYCLIC COMPOUNDS; HUMANS; IMMUNOHISTOCHEMISTRY; MELANOMA; METHANE; MICE; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84899572821     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-57     Document Type: Article

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