Impaired exercise-induced mitochondrial biogenesis in the obese Zucker rat, despite PGC-1α induction, is due to compromised mitochondrial translation elongation

American Journal of Physiology - Endocrinology and Metabolism

Volumn 306, Issue 5, 2014, Pages

  Greene, Nicholas P ^a,b   Nilsson, Mats I ^a   Washington, Tyrone A ^b   Lee, David E ^b   Brown, Lemuel A ^b   Papineau, Alyssa M ^b   Shimkus, Kevin L ^a   Greene, Elizabeth S ^a   Crouse, Stephen F ^a   Fluckey, James D ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF ARKANSAS   (United States)

Author keywords

Mitochondrial protein synthesis; Mitochondrial transcription and translation; Oxidative metabolism; Peroxisome proliferator activated receptor coactivator 1

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE I; ELONGATION FACTOR TU; INITIATION FACTOR 2; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PPARGC1A PROTEIN, RAT; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CONTROLLED STUDY; DIABETES MELLITUS; EXERCISE; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL GENOME; MITOCHONDRION; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; RESISTANCE TRAINING; UPREGULATION; ZUCKER RAT; AEROBIC METABOLISM; ANIMAL; GENETICS; METABOLISM; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEIN SYNTHESIS; MITOCHONDRIAL TRANSCRIPTION AND TRANSLATION; MUSCLE MITOCHONDRION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-Γ COACTIVATOR-1Α; PHOSPHORYLATION; PHYSIOLOGY;

MITOCHONDRIAL PROTEIN SYNTHESIS; MITOCHONDRIAL TRANSCRIPTION AND TRANSLATION; OXIDATIVE METABOLISM; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-Γ COACTIVATOR-1Α;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; MITOCHONDRIA; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL TURNOVER; OBESITY; PHOSPHORYLATION; PHYSICAL CONDITIONING, ANIMAL; PPAR DELTA; RATS; RATS, ZUCKER; TRANSCRIPTION FACTORS;

EID: 84899539796     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00671.2013     Document Type: Article

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