HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition

Laboratory Investigation

Volumn 94, Issue 5, 2014, Pages 557-568

  Ekman, Mari ^a,b   Uvelius, Bengt ^c   Albinsson, Sebastian ^a   Swärd, Karl ^a  

^a LUND UNIVERSITY   (Sweden)

^b Faculty of Engineering   (Sweden)

^c LUND UNIVERSITY   (Sweden)

Author keywords

Bnip3; Edn1; LC3 II; P4ha1; Slc2a3

Indexed keywords

ARNT2 PROTEIN; CYANIDE; CYTOCHROME C OXIDASE; CYTOCHROME C OXIDASE SUBUNIT 4; ENOLASE 1; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 3; GLYCOLYTIC ENZYME; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; HYPOXIA INDUCIBLE FACTOR 3ALPHA; LACTATE DEHYDROGENASE; PROTEIN BNIP3; TRANSCRIPTION FACTOR; TRIOSEPHOSPHATE ISOMERASE 1; UNCLASSIFIED DRUG;

ANAEROBIC GLYCOLYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; BINDING SITE; BLADDER NECK STENOSIS; CONTROLLED STUDY; FEMALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; TRANSCRIPTION INITIATION; UPREGULATION; WESTERN BLOTTING;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; FEMALE; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; GLYCOLYSIS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISOENZYMES; L-LACTATE DEHYDROGENASE; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MUSCLE, SMOOTH; RATS; RATS, SPRAGUE-DAWLEY; URINARY BLADDER NECK OBSTRUCTION;

EID: 84899527570     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2014.48     Document Type: Article

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