The ratio between CcdA and CcdB modulates the transcriptional repression of the ccd poison-antidote system

Molecular Microbiology

Volumn 41, Issue 1, 2001, Pages 73-82

  Afif, H ^a   Allali, N ^a   Couturier, M ^a   Van Melderen, L ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; DNA BINDING PROTEIN; PROTEIN CCDA; PROTEIN CCDB; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; DNA BINDING; ELECTROPHORETIC MOBILITY; ESCHERICHIA COLI; NONHUMAN; OPERATOR GENE; OPERON; PLASMID; PRIORITY JOURNAL; PROTEIN DNA BINDING; REPORTER GENE; STOICHIOMETRY; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; BACTERIAL TOXINS; DNA, BACTERIAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; MUTATION; OPERATOR REGIONS (GENETICS); OPERON; PLASMIDS; PROMOTER REGIONS (GENETICS); TRANSCRIPTION, GENETIC;

EID: 0034939217     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2001.02492.x     Document Type: Article

References (30)

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2. The 41 carboxyterminal residues of the mini-F plasmid CcdA protein are sufficient to antagonize the killer activity of the CcdB protein
3. Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes
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5. Regulation of ribosomal RNA promoters with a synthetic lac operator
6. Bacterial death by DNA gyrase poisoning
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11. The Escherichia coli relBE genes belong to a new toxin-antitoxin gene family
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13. Plasmid copy-number control and better-than-random segregation genes of pSM19035 share a common regulator
14. Dominant negative mutations in the Tn10 tet repressor: Evidence for use of the conserved helix-turn-helix motif in DNA binding
15. Plasmid RK2 toxin protein ParE: Purification and interaction with the ParD antitoxin protein
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17. Autoregulation of the plasmid addiction operon of bacteriophage P1
18. Characteristics and significance of DNA binding activity of plasmid stabilization protein ParD from the broad-host-range plasmid RK2
19. The kis and kid genes of the parD maintenance system of plasmid R1 form an operon that is autoregulated at the level of transcription by the coordinated action of the kis and kid proteins
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21. Autoregulation of the pTF-FC2 proteic poison-antidote plasmid addiction system (pas) is essential for plasmid stabilization
22. Crystal structure of the met repressor-operator complex at 2.8 A resolution reveals DNA recognition by beta-strands
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24. DNA recognition by a beta-sheet
25. Control of the ccd operon in plasmid F
26. The F plasmid ccd autorepressor is a complex of CcdA and CcdB proteins
27. Lond-dependent proteolysis of CcdA is the key control for activation of CcdB in plasmid-free segregant bacteria
28. ATP-dependent degradation of CcdA by Lon protease. Effects of secondary structure and heterologous subunit interactions