-
1
-
-
0034502538
-
Alternative administration of camptothecin analogues
-
Verschraegen, C.F.; Jaeckle, K. Alternative administration of camptothecin analogues. Ann. N.Y. Acad. Sci. 2000, 922, 237-246.
-
(2000)
Ann. N.Y. Acad. Sci
, vol.922
, pp. 237-246
-
-
Verschraegen, C.F.1
Jaeckle, K.2
-
2
-
-
0024358188
-
Dna-topoisomerase i-targeted chemotherapy of human colon cancer in xenografts
-
Giovanell, B.C.; Stehlin, J.S. DNA-topoisomerase I-targeted chemotherapy of human colon cancer in xenografts. Science 1989, 246, 1046-1048.
-
(1989)
Science
, vol.246
, pp. 1046-1048
-
-
Giovanell, B.C.1
Stehlin, J.S.2
-
3
-
-
0022340594
-
Camptothecin induces protein-linked dna breaks via mammalian dna topoisomerase i
-
Hsiang, Y.H.; Hertzberg, R. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J. Biol. Chem. 1985, 260, 14873-14878.
-
(1985)
J. Biol. Chem
, vol.260
, pp. 14873-14878
-
-
Hsiang, Y.H.1
Hertzberg, R.2
-
4
-
-
0034687233
-
The novel silatecan 7-tert-butyldimethylsilyl-10-hydroxycamptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity
-
Bom, D.; Curran, D.P. The novel silatecan 7-tert-butyldimethylsilyl-10- hydroxycamptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity. J. Med. Chem. 2000, 43, 3970-3980.
-
(2000)
J. Med. Chem
, vol.43
, pp. 3970-3980
-
-
Bom, D.1
Curran, D.P.2
-
5
-
-
0033809224
-
New highly lipophilic camptothecin bnp1350 is an effective drug in experimental human cancer. Int
-
Van Hattum, A.H.; Pinedo, H.M. New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer. Int. J .Cancer. 2000, 88, 260-266.
-
(2000)
J .Cancer
, vol.88
, pp. 260-266
-
-
Van Hattum, A.H.1
Pinedo, H.M.2
-
6
-
-
33748754360
-
Synthesis and antitumor activity of novel 10-substituted camptothecin analogues
-
Li, Q.Y.; Zu, Y.G.; Shi, R.Z. Synthesis and antitumor activity of novel 10-substituted camptothecin analogues. Bioorg. Med. Chem. 2006, 14, 7175-7182.
-
(2006)
Bioorg. Med. Chem
, vol.14
, pp. 7175-7182
-
-
Li, Q.Y.1
Zu, Y.G.2
Shi, R.Z.3
-
7
-
-
57749086734
-
Synthesis and antitumor activity of novel 20s-camptothecin analogues
-
Li, Q.Y.; Lv, H.Y. Synthesis and antitumor activity of novel 20s-camptothecin analogues. Bioorg. Med. Chem. Lett. 2009, 19, 513-515.
-
(2009)
Bioorg. Med. Chem. Lett
, vol.19
, pp. 513-515
-
-
Li, Q.Y.1
Lv, H.Y.2
-
8
-
-
67549086098
-
Abrus abrin derived peptides induce apoptosis by targeting mitochondria in hela cells
-
Bhutia, S.K.; Mallick, S.K. Abrus abrin derived peptides induce apoptosis by targeting mitochondria in HeLa cells. Cell Biol. International 2009, 33, 720-727.
-
(2009)
Cell Biol. International
, vol.33
, pp. 720-727
-
-
Bhutia, S.K.1
Mallick, S.K.2
-
9
-
-
0035359505
-
Exploiting cancer cell cycling for selective protection of normal cells
-
Blagosklonny, M.V.; Pardee, A.B. Exploiting cancer cell cycling for selective protection of normal cells. Cancer Res. 2002, 61, 4301-4305.
-
(2002)
Cancer Res
, vol.61
, pp. 4301-4305
-
-
Blagosklonny, M.V.1
Pardee, A.B.2
-
10
-
-
33748065983
-
Antiproliferative cytotoxic and apoptogenic activity of indian toad (bufo melanostictus, schneider) skin extract on u937 and k562 cells
-
Giri, B.; Gomes, A. Antiproliferative, cytotoxic and apoptogenic activity of Indian toad (Bufo melanostictus, Schneider) skin extract on U937 and K562 cells. Toxicon 2006. 48, 388-400.
-
(2006)
Toxicon
, vol.48
, pp. 388-400
-
-
Giri, B.1
Gomes, A.2
-
11
-
-
35548991912
-
Therapeutic efficacy of nsc606985, a novel camptothecin analog, in a mouse model of acute promyelocytic leukemia
-
Liu, W.; Zhu, Y.S. Therapeutic efficacy of NSC606985, a novel camptothecin analog, in a mouse model of acute promyelocytic leukemia. Leukemia Res. 2007, 31, 1565-1574.
-
(2007)
Leukemia Res
, vol.31
, pp. 1565-1574
-
-
Liu, W.1
Zhu, Y.S.2
-
12
-
-
1542330612
-
Subcellular localization of the camptothecin analogues, topotecan and gimatecan
-
Croce, A.C.; Bottiroli, G. Subcellular localization of the camptothecin analogues, topotecan and gimatecan. Biochem. Pharm. 2004, 67, 1035-1045
-
(2004)
Biochem. Pharm
, vol.67
, pp. 1035-1045
-
-
Croce, A.C.1
Bottiroli, G.2
-
13
-
-
0036802946
-
Measurement of the intracellular distribution of reduced glutathione in cultured rat hepatocytes using monochlorobimane and confocallaser scanning microscopy
-
Stevenson, D.; Wokosin, D. Measurement of the intracellular distribution of reduced glutathione in cultured rat hepatocytes using monochlorobimane and confocallaser scanning microscopy. Toxicol. In Vitro. 2002, 16, 609-619.
-
(2002)
Toxicol. In Vitro
, vol.16
, pp. 609-619
-
-
Stevenson, D.1
Wokosin, D.2
-
14
-
-
51049100659
-
Activation of the mitochondria-driven pathway of apoptosis in human pc-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel
-
Jiang, S.G.; Zu, Y.G. Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel. Int. J. Oncol. 2008, 33, 103-111.
-
(2008)
Int. J. Oncol
, vol.33
, pp. 103-111
-
-
Jiang, S.G.1
Zu, Y.G.2
-
15
-
-
34247098521
-
Morphological study on apoptosis hela cells induced by soyasaponins
-
Xiao, X.J.; Huang, G.Q. Morphological study on apoptosis Hela cells induced by soyasaponins. Toxicol. in Vitro 2007, 21, 820-826.
-
(2007)
Toxicol. In Vitro
, vol.21
, pp. 820-826
-
-
Xiao, X.J.1
Huang, G.Q.2
-
16
-
-
34547668617
-
Soyasaponins inhibit the proliferation of hela cells by inducing apoptosis
-
Xiao, J.X.; Huang, G.Q. Soyasaponins inhibit the proliferation of Hela cells by inducing apoptosis. Exp. Toxicol. Pathol. 2007, 59, 35-42.
-
(2007)
Exp. Toxicol. Pathol
, vol.59
, pp. 35-42
-
-
Xiao, J.X.1
Huang, G.Q.2
-
17
-
-
33947246636
-
Chimmitecan a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo
-
Huang, M.; Gao, H.Y. Chimmitecan, a novel 9-substituted Camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo. Clin. Cancer Res. 2007, 13, 1298-1307.
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 1298-1307
-
-
Huang, M.1
Gao, H.Y.2
-
18
-
-
34250308322
-
Apoptosis: A review of programmed cell death
-
Elmore, S. Apoptosis: A review of programmed cell death. Toxicol. Pathol. 2007, 35, 495-516.
-
(2007)
Toxicol. Pathol
, vol.35
, pp. 495-516
-
-
Elmore, S.1
-
19
-
-
27644542306
-
Apoptosis: Mechanisms and relevance in cancer
-
Vermeulen, K.; Van Bockstaele, D.R. Apoptosis: Mechanisms and relevance in cancer. Ann. Hematol. 2005, 84, 627-639.
-
(2005)
Ann. Hematol
, vol.84
, pp. 627-639
-
-
Vermeulen, K.1
Van Bockstaele, D.R.2
-
20
-
-
0042833078
-
Apoptosis-based drug screening and detection of selective toxicity to cancer cells
-
Frankfurt, O.S.; Krishan, A. Apoptosis-based drug screening and detection of selective toxicity to cancer cells. Anticancer Drugs 2003, 14, 555-561.
-
(2003)
Anticancer Drugs
, vol.14
, pp. 555-561
-
-
Frankfurt, O.S.1
Krishan, A.2
-
21
-
-
0024316466
-
Dna topoisomerase poisons as antitumor drugs
-
Liu, L.F. DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem. 1989, 58, 351-375.
-
(1989)
Annu. Rev. Biochem
, vol.58
, pp. 351-375
-
-
Liu, L.F.1
-
22
-
-
0025133118
-
Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons
-
D'Arpa, P.; Beardmore, C. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. Cancer Res. 1990, 50, 6919-24.
-
(1990)
Cancer Res
, vol.50
, pp. 6919-6924
-
-
D'Arpa, P.1
Beardmore, C.2
-
23
-
-
0032544268
-
Apoptotic pathways: The roads to run
-
Green, D.R. Apoptotic pathways: The roads to run. Cell 1998, 94, 695-698.
-
(1998)
Cell
, vol.94
, pp. 695-698
-
-
Green, D.R.1
-
24
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan, M.B.; Bartek, J. Cell-cycle checkpoints and cancer. Nature 2004, 432, 316-323.
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
25
-
-
67349252446
-
Downregulation of plk-1 expression in kaempferol-induced apoptosis of mcf-7 cells
-
Kang, G.Y.; Lee, E.R. Downregulation of PLK-1 expression in kaempferol-induced apoptosis of MCF-7 cells. Eur. J. Pharmacol. 2009, 611, 17-21.
-
(2009)
Eur. J. Pharmacol
, vol.611
, pp. 17-21
-
-
Kang, G.Y.1
Lee, E.R.2
-
26
-
-
0029043888
-
A novel assay for apoptosis, flow cytometric detection of phosphatidylserin expression on early apoptotic cells using fluorescein labeled annexin-v
-
Vermes, I.; Haanen, C. A novel assay for apoptosis, Flow cytometric detection of phosphatidylserin expression on early apoptotic cells using fluorescein labeled annexin-V. J. Immunol. Meth. 1995, 184, 39-51.
-
(1995)
J. Immunol. Meth
, vol.184
, pp. 39-51
-
-
Vermes, I.1
Haanen, C.2
-
27
-
-
33748622045
-
Hydroxycamptothecin-induced apoptosis in hepatoma smmc-7721 cells and the role of mitochondrial pathway
-
Fu, Y.R.; Yi, Z.J. Hydroxycamptothecin-induced apoptosis in hepatoma SMMC-7721 cells and the role of mitochondrial pathway. Mitochondrion 2006, 6, 211-217.
-
(2006)
Mitochondrion
, vol.6
, pp. 211-217
-
-
Fu, Y.R.1
Yi, Z.J.2
-
28
-
-
33744507693
-
Interrelated roles for mcl-1 and bim in regulation of trail-mediated mitochondrial apoptosis
-
Han, J.; Goldstein, L.A. Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis. J. Biol. Chem. 2006, 281, 10153-10163.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 10153-10163
-
-
Han, J.1
Goldstein, L.A.2
-
29
-
-
0035678526
-
Validation of confocal laser scanning microscopy for detecting intracellular calcium heterogeneity in live slices
-
Yoneyama, K. Validation of confocal laser scanning microscopy for detecting intracellular calcium heterogeneity in live slices. J. Pharmacol. Toxicol. Methods 2001, 45, 187-193.
-
(2001)
J. Pharmacol. Toxicol. Methods
, vol.45
, pp. 187-193
-
-
Yoneyama, K.1
|