메뉴 건너뛰기




Volumn 59, Issue 1, 2007, Pages 35-42

Soyasaponins inhibit the proliferation of Hela cells by inducing apoptosis

Author keywords

Apoptosis; Cell cycle; Intracellular Ca2+< sup>; Mitochondrial transmembrane potential; Nitric oxide; Soyasaponins

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SAPONIN DERIVATIVE; SOYASAPONIN 2; UNCLASSIFIED DRUG;

EID: 34547668617     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2007.02.004     Document Type: Article
Times cited : (40)

References (26)
  • 1
    • 0035282782 scopus 로고    scopus 로고
    • Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase
    • Brown G.C. Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase. Biochim Biophys Acta 1504 (2001) 46-57
    • (2001) Biochim Biophys Acta , vol.1504 , pp. 46-57
    • Brown, G.C.1
  • 2
    • 13444252965 scopus 로고    scopus 로고
    • Induction of macroautophagy in human colon cancer cells by soybean B-group triterpenoid saponins
    • Ellington A.A., Berhow M.A., and Singletary K.W. Induction of macroautophagy in human colon cancer cells by soybean B-group triterpenoid saponins. Carcinogenesis 26 (2005) 159-167
    • (2005) Carcinogenesis , vol.26 , pp. 159-167
    • Ellington, A.A.1    Berhow, M.A.2    Singletary, K.W.3
  • 3
    • 31544461235 scopus 로고    scopus 로고
    • Inhibition of Akt signaling and enhanced ERK1/2 activity are involved in induction of macroautophagy by triterpenoid B-group soyasaponins in colon cancer cells
    • Ellington A.A., Berhow M.A., and Singletary K.W. Inhibition of Akt signaling and enhanced ERK1/2 activity are involved in induction of macroautophagy by triterpenoid B-group soyasaponins in colon cancer cells. Carcinogenesis 27 (2006) 298-306
    • (2006) Carcinogenesis , vol.27 , pp. 298-306
    • Ellington, A.A.1    Berhow, M.A.2    Singletary, K.W.3
  • 4
    • 0042833078 scopus 로고    scopus 로고
    • Apoptosis-based drug screening and detection of selective toxicity to cancer cells
    • Frankfurt O.S., and Krishan A. Apoptosis-based drug screening and detection of selective toxicity to cancer cells. Anticancer Drugs 14 (2003) 555-561
    • (2003) Anticancer Drugs , vol.14 , pp. 555-561
    • Frankfurt, O.S.1    Krishan, A.2
  • 5
    • 0030858410 scopus 로고    scopus 로고
    • Identification of soyasaponins by liquid chromatography-thermospray mass spectrometry
    • Fuzzati N., Pace R., Papeo G., and Peterlongo F. Identification of soyasaponins by liquid chromatography-thermospray mass spectrometry. J Chromatogr A 777 (1997) 233-238
    • (1997) J Chromatogr A , vol.777 , pp. 233-238
    • Fuzzati, N.1    Pace, R.2    Papeo, G.3    Peterlongo, F.4
  • 6
    • 14644433040 scopus 로고    scopus 로고
    • Selective induction of apoptosis in murine skin carcinoma cells (CH72) by an ethanol extract of Lentinula edodes
    • Gu Y.H., and Belury M.A. Selective induction of apoptosis in murine skin carcinoma cells (CH72) by an ethanol extract of Lentinula edodes. Cancer Lett 220 (2005) 21-28
    • (2005) Cancer Lett , vol.220 , pp. 21-28
    • Gu, Y.H.1    Belury, M.A.2
  • 7
    • 1342344072 scopus 로고    scopus 로고
    • Soyasaponins: the relationship between chemical structure and colon anticarcinogenic activity
    • Gurfinkel D.M., and Rao A.V. Soyasaponins: the relationship between chemical structure and colon anticarcinogenic activity. Nutr Cancer 47 (2003) 24-33
    • (2003) Nutr Cancer , vol.47 , pp. 24-33
    • Gurfinkel, D.M.1    Rao, A.V.2
  • 8
    • 2942555293 scopus 로고    scopus 로고
    • Role of intracellular calcium ions and reactive oxygen species in apoptosis induced by ultrasound
    • Honda H., Kondo T., Zhao Q.L., Feril Jr. L.B., and Kitagawa H. Role of intracellular calcium ions and reactive oxygen species in apoptosis induced by ultrasound. Ultrasound Med Biol 30 (2004) 683-692
    • (2004) Ultrasound Med Biol , vol.30 , pp. 683-692
    • Honda, H.1    Kondo, T.2    Zhao, Q.L.3    Feril Jr., L.B.4    Kitagawa, H.5
  • 9
    • 34247118425 scopus 로고    scopus 로고
    • Study on the inhibitory effects of soybean saponins on human hepatoma cell
    • Huang J., Zhang M., Li Z., Niu W., and Zhang S.H. Study on the inhibitory effects of soybean saponins on human hepatoma cell. Acta Nutr Sin 26 (2004) 477-481
    • (2004) Acta Nutr Sin , vol.26 , pp. 477-481
    • Huang, J.1    Zhang, M.2    Li, Z.3    Niu, W.4    Zhang, S.H.5
  • 10
    • 2542482634 scopus 로고    scopus 로고
    • Antiproliferative crude soy saponin extract modulates the expression of IκBα, protein kinase C, and cyclooxygenase-2 in human colon cancer cells
    • Kim H.Y., Yu R., Kim J.S., Kim Y.K., and Sung M.K. Antiproliferative crude soy saponin extract modulates the expression of IκBα, protein kinase C, and cyclooxygenase-2 in human colon cancer cells. Cancer Lett 210 (2004) 1-6
    • (2004) Cancer Lett , vol.210 , pp. 1-6
    • Kim, H.Y.1    Yu, R.2    Kim, J.S.3    Kim, Y.K.4    Sung, M.K.5
  • 11
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
    • Kluck R.M., Bossy-Wetzel E., Green D.R., and Newmeyer D.D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275 (1997) 1132-1136
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 12
    • 0033288336 scopus 로고    scopus 로고
    • Mitochondrial control of apoptosis: an overview
    • Kroemer G. Mitochondrial control of apoptosis: an overview. Biochem Soc Symp 66 (1999) 1-15
    • (1999) Biochem Soc Symp , vol.66 , pp. 1-15
    • Kroemer, G.1
  • 13
    • 0033010612 scopus 로고    scopus 로고
    • Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death
    • Lorenzo H.K., Susin S.A., Penninger J., and Kroemer G. Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death. Cell Death Differ 6 (1999) 516-524
    • (1999) Cell Death Differ , vol.6 , pp. 516-524
    • Lorenzo, H.K.1    Susin, S.A.2    Penninger, J.3    Kroemer, G.4
  • 14
    • 0031581060 scopus 로고    scopus 로고
    • Breakthroughs and views: the role of calcium in the regulation of apoptosis
    • McConkey D.J., and Orrenius S. Breakthroughs and views: the role of calcium in the regulation of apoptosis. Biochem Biophys Res Commun 239 (1997) 357-366
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 357-366
    • McConkey, D.J.1    Orrenius, S.2
  • 15
    • 84939579645 scopus 로고    scopus 로고
    • The inhibitory effects of soyasaponin on DNA synthesis of tumor cells
    • Ming Y., Li R., and Jin J.S. The inhibitory effects of soyasaponin on DNA synthesis of tumor cells. Acad Peri Changchun Coll Tradit Chin Med 16 (2000) 48-49
    • (2000) Acad Peri Changchun Coll Tradit Chin Med , vol.16 , pp. 48-49
    • Ming, Y.1    Li, R.2    Jin, J.S.3
  • 16
    • 0034820449 scopus 로고    scopus 로고
    • Soybean saponins inhibit cell proliferation by suppressing PKC activation and induce differentiation of HT-29 human colon adenocarcinoma cells
    • Oh Y.J., and Sung M.K. Soybean saponins inhibit cell proliferation by suppressing PKC activation and induce differentiation of HT-29 human colon adenocarcinoma cells. Nutr Cancer 39 (2001) 132-138
    • (2001) Nutr Cancer , vol.39 , pp. 132-138
    • Oh, Y.J.1    Sung, M.K.2
  • 18
    • 0002927649 scopus 로고    scopus 로고
    • Role of nitric oxide in gastrointestinal tract
    • Rachmilewitz D. Role of nitric oxide in gastrointestinal tract. World J Gastroenterol 4 (1998) 28-29
    • (1998) World J Gastroenterol , vol.4 , pp. 28-29
    • Rachmilewitz, D.1
  • 19
    • 0028876822 scopus 로고
    • Saponins as anticarcinogens
    • Rao A.V., and Sung M.K. Saponins as anticarcinogens. J Nutr 125 (1995) 717S-724S
    • (1995) J Nutr , vol.125
    • Rao, A.V.1    Sung, M.K.2
  • 20
    • 0034953632 scopus 로고    scopus 로고
    • Apoptosis-regulating proteins as targets for drug discovery
    • Reed J.C. Apoptosis-regulating proteins as targets for drug discovery. Trend Mol Med 7 (2001) 314-319
    • (2001) Trend Mol Med , vol.7 , pp. 314-319
    • Reed, J.C.1
  • 21
    • 0032171420 scopus 로고    scopus 로고
    • Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide
    • Wink D.A., and Mitchell J.B. Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide. Free Radic Biol Med 25 (1998) 434-456
    • (1998) Free Radic Biol Med , vol.25 , pp. 434-456
    • Wink, D.A.1    Mitchell, J.B.2
  • 22
    • 34247125734 scopus 로고    scopus 로고
    • Study on soyasaponins by HPLC-electrospray ionization tandem mass spectrometry
    • Xiao J.X., and Zhang S.H. Study on soyasaponins by HPLC-electrospray ionization tandem mass spectrometry. Zhong Yao Cai 29 (2006) 229-232
    • (2006) Zhong Yao Cai , vol.29 , pp. 229-232
    • Xiao, J.X.1    Zhang, S.H.2
  • 23
    • 0038199818 scopus 로고    scopus 로고
    • Triterpenoids from Glycine max decrease invasiveness and induce caspase-mediated cell death in human SNB19 glioma cells
    • Yanamandra N., Berhow M.A., Konduri S., Dinh D.H., Olivero W.C., Nicolson G.L., et al. Triterpenoids from Glycine max decrease invasiveness and induce caspase-mediated cell death in human SNB19 glioma cells. Clin Exp Metastasis 20 (2003) 375-383
    • (2003) Clin Exp Metastasis , vol.20 , pp. 375-383
    • Yanamandra, N.1    Berhow, M.A.2    Konduri, S.3    Dinh, D.H.4    Olivero, W.C.5    Nicolson, G.L.6
  • 24
    • 0035678526 scopus 로고    scopus 로고
    • Validation of confocal laser scanning microscopy for detecting intracellular calcium heterogeneity in liver slices
    • Yoneyama K. Validation of confocal laser scanning microscopy for detecting intracellular calcium heterogeneity in liver slices. J Pharmacol Toxicol Methods 45 (2001) 187-193
    • (2001) J Pharmacol Toxicol Methods , vol.45 , pp. 187-193
    • Yoneyama, K.1
  • 25
  • 26
    • 84939576688 scopus 로고    scopus 로고
    • Influence of total soyasaponin on transplant tumor growth in mice
    • Yu L.P., Yu Y.Q., Lu Z., Wang C.Y., and Li X.Y. Influence of total soyasaponin on transplant tumor growth in mice. China Oncol 6 (1996) 186-188
    • (1996) China Oncol , vol.6 , pp. 186-188
    • Yu, L.P.1    Yu, Y.Q.2    Lu, Z.3    Wang, C.Y.4    Li, X.Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.