IgE regulates the expression of smMLCK in human airway smooth muscle cells

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Balhara, Jyoti ^a   Redhu, Naresh Singh ^a   Shan, Lianyu ^a   Gounni, Abdelilah S ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD23 ANTIGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOSIN LIGHT CHAIN KINASE; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE SYK; STRESS ACTIVATED PROTEIN KINASE; FC RECEPTOR; FCGR1A PROTEIN, HUMAN; LYN PROTEIN-TYROSINE KINASE; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE;

ALLERGIC ASTHMA; ARTICLE; BREATHING MUSCLE; BRONCHUS TONE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOREGULATION; PROTEIN EXPRESSION; PROTEIN TARGETING; SMOOTH MUSCLE FIBER; UPREGULATION; ASTHMA; CELL CYCLE; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HYPERSENSITIVITY; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ASTHMA; CELL CYCLE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE SIGNALING SYSTEM; MYOCYTES, SMOOTH MUSCLE; MYOSIN-LIGHT-CHAIN KINASE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN-TYROSINE KINASES; RECEPTORS, IGG; RNA, MESSENGER; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84899501314     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093946     Document Type: Article

References (58)

1. Hamid Q, Tulic M (2009) Immunobiology of asthma. Annu Rev Physiol 71: 489-507.
2. Hamid Q, Tulic MK, Liu MC, Moqbel R (2003) Inflammatory cells in asthma: mechanisms and implications for therapy. J Allergy Clin Immunol 111: S5-S12; discussion S12-17.
3. Hershenson MB, Brown M, Camoretti-Mercado B, Solway J (2008) Airway smooth muscle in asthma. Annu Rev Pathol 3: 523-555. (Pubitemid 351488292)
4. The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma(2003) European Network for Understanding Mechanisms of Severe Asthma. Eur Respir J 22: 470-477.
5. Peat JK, Toelle BG, Dermand J, van den Berg R, Britton WJ, et al. (1996) Serum IgE levels, atopy, and asthma in young adults: results from a longitudinal cohort study. Allergy 51: 804-810. (Pubitemid 26384214)
6. Prausnitz C, Kustner H (1921) Studien der Überempfindlichkeit. Centralb Bakteriolog 1 Abt Orig 86: 160-168.
7. Ma X, Stephens NL (1997) The cytoskeleton and the extracellular matrix in sensitized canine tracheal smooth muscle. Respir Physiol 110: 57-66. (Pubitemid 27438272)
8. Kong SK, Halayko AJ, Stephens NL (1990) Increased myosin phosphorylation in sensitized canine tracheal smooth muscle. Am J Physiol 259: L53-56. (Pubitemid 20257233)
9. Watson N, Bodtke K, Coleman RA, Dent G, Morton BE, et al. (1997) Role of IgE in hyperresponsiveness induced by passive sensitization of human airways. Am J Respir Crit Care Med 155: 839-844. (Pubitemid 27133391)
10. Souhrada M, Souhrada JF (1984) Immunologically induced alterations of airway smooth muscle cell membrane. Science 225: 723-725. (Pubitemid 14054318)
11. Kamm KE, Stull JT (1985) The function of myosin and myosin light chain kinase phosphorylation in smooth muscle. Annu Rev Pharmacol Toxicol 25: 593-620. (Pubitemid 15090995)
12. Zhang WC, Peng YJ, Zhang GS, He WQ, Qiao YN, et al. (2010) Myosin light chain kinase is necessary for tonic airway smooth muscle contraction. J Biol Chem 285: 5522-5531.
13. Slats AM, Janssen K, van Schadewijk A, van der Plas DT, Schot R, et al. (2008) Expression of smooth muscle and extracellular matrix proteins in relation to airway function in asthma. J Allergy Clin Immunol 121: 1196-1202.
14. Ammit AJ, Armour CL, Black JL (2000) Smooth-muscle myosin light-chain kinase content is increased in human sensitized airways. Am J Respir Crit Care Med 161: 257-263. (Pubitemid 30055934)
15. Jiang H, Rao K, Halayko AJ, Liu X, Stephens NL (1992) Ragweed sensitization-induced increase of myosin light chain kinase content in canine airway smooth muscle. Am J Respir Cell Mol Biol 7: 567-573.
16. Ma X, Cheng Z, Kong H, Wang Y, Unruh H, et al. (2002) Changes in biophysical and biochemical properties of single bronchial smooth muscle cells from asthmatic subjects. Am J Physiol Lung Cell Mol Physiol 283: L1181-1189. (Pubitemid 35379249)
17. Gounni AS, Wellemans V, Yang J, Bellesort F, Kassiri K, et al. (2005) Human airway smooth muscle cells express the high affinity receptor for IgE (Fc epsilon RI): a critical role of Fc epsilon RI in human airway smooth muscle cell function. J Immunol 175: 2613-2621. (Pubitemid 41113875)
18. Roth M, Tamm M (2010) The effects of omalizumab on IgE-induced cytokine synthesis by asthmatic airway smooth muscle cells. Ann Allergy Asthma Immunol 104: 152-160.
19. Redhu NS, Saleh A, Shan L, Gerthoffer WT, Kung SK, et al. (2009) Proinflammatory and Th2 cytokines regulate the high affinity IgE receptor (FcepsilonRI) and IgE-dependant activation of human airway smooth muscle cells. PLoS One 4: e6153.
20. Xia YC, Schuliga M, Shepherd M, Powell M, Harris T, et al. (2011) Functional expression of IgG-Fc receptors in human airway smooth muscle cells. Am J Respir Cell Mol Biol 44: 665-672.
21. Redhu NS, Shan L, Gounni AS (2012) Fcepsilon receptor expression in human airway smooth muscle cells. Am J Respir Cell Mol Biol 46: 559-560; author reply 560-551.
22. Redhu NS, Gounni AS (2013) The high affinity IgE receptor (FcepsilonRI) expression and function in airway smooth muscle. Pulm Pharmacol Ther 26: 86-94.
23. Redhu NS, Saleh A, Lee HC, Halayko AJ, Ziegler SF, et al. (2011) IgE induces transcriptional regulation of thymic stromal lymphopoietin in human airway smooth muscle cells. J Allergy Clin Immunol.
24. Gosens R, Stelmack GL, Dueck G, McNeill KD, Yamasaki A, et al. (2006) Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 291: L523-534. (Pubitemid 44343730)
25. Rahman MS, Yamasaki A, Yang J, Shan L, Halayko AJ, et al. (2006) IL-17A induces eotaxin-1/CC chemokine ligand 11 expression in human airway smooth muscle cells: role of MAPK (Erk1/2, JNK, and p38) pathways. J Immunol 177: 4064-4071. (Pubitemid 44359940)
26. Gerthoffer WT, Pari GS, Wysolmerski RB (2004) Immortalized human airway smooth muscle cells with a contractile phenotype (Abstract). Am J Respir Crit Care Med: A188.
27. Benayoun L, Druilhe A, Dombret MC, Aubier M, Pretolani M (2003) Airway structural alterations selectively associated with severe asthma. Am J Respir Crit Care Med 167: 1360-1368. (Pubitemid 36609720)
28. Wang B, Rieger A, Kilgus O, Ochiai K, Maurer D, et al. (1992) Epidermal Langerhans cells from normal human skin bind monomeric IgE via Fc epsilon RI. J Exp Med 175: 1353-1365.
29. Nechansky A, Pursch E, Effenberger F, Kricek F (1997) Characterization of monoclonal antibodies directed against the alpha-subunit of the human IgE high-affinity receptor. Hybridoma 16: 441-446. (Pubitemid 27486218)
30. Kraft S, Kinet JP (2007) New developments in FcepsilonRI regulation, function and inhibition. Nat Rev Immunol 7: 365-378. (Pubitemid 46674486)
31. Griffith QK, Liang Y, Onguru DO, Mwinzi PN, Ganley-Leal LM (2011) CD23-bound IgE augments and dominates recall responses through human naive B cells. J Immunol 186: 1060-1067.
32. Kalesnikoff J, Huber M, Lam V, Damen JE, Zhang J, et al. (2001) Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival. Immunity 14: 801-811. (Pubitemid 32592426)
33. Saffar AS, Alphonse MP, Shan L, Hayglass KT, Simons FE, et al. (2007) IgE modulates neutrophil survival in asthma: role of mitochondrial pathway. J Immunol 178: 2535-2541. (Pubitemid 46233455)
34. Katoh N, Kraft S, Wessendorf JH, Bieber T (2000) The high-affinity IgE receptor (FcepsilonRI) blocks apoptosis in normal human monocytes. J Clin Invest 105: 183-190. (Pubitemid 30054357)
35. Redhu NS, Gounni AS (2012) The high affinity IgE receptor (FcepsilonRI) expression and function in airway smooth muscle. Pulm Pharmacol Ther.
36. Nechansky A, Aschauer H, Kricek F (1998) The membrane-proximal part of FcepsilonRIalpha contributes to human IgE and antibody binding-implications for a general structural motif in Fc receptors. FEBS Lett 441: 225-230. (Pubitemid 29027900)
37. Wu LC (2011) Immunoglobulin E receptor signaling and asthma. J Biol Chem 286: 32891-32897.
38. Kinet JP (1999) The high-affinity IgE receptor (Fc epsilon RI): from physiology to pathology. Annu Rev Immunol 17: 931-972.
39. Ortega E, Lara M, Lee I, Santana C, Martinez AM, et al. (1999) Lyn dissociation from phosphorylated Fc epsilon RI subunits: a new regulatory step in the Fc epsilon RI signaling cascade revealed by studies of Fc epsilon RI dimer signaling activity. J Immunol 162: 176-185. (Pubitemid 29018918)
40. Lara M, Ortega E, Pecht I, Pfeiffer JR, Martinez AM, et al. (2001) Overcoming the signaling defect of Lyn-sequestering, signal-curtailing FcepsilonRI dimers: aggregated dimers can dissociate from Lyn and form signaling complexes with Syk. J Immunol 167: 4329-4337. (Pubitemid 32954308)
41. Beavitt SJ, Harder KW, Kemp JM, Jones J, Quilici C, et al. (2005) Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity. J Immunol 175: 1867-1875. (Pubitemid 41023093)
42. Yamashita Y, Charles N, Furumoto Y, Odom S, Yamashita T, et al. (2007) Cutting edge: genetic variation influences Fc epsilonRI-induced mast cell activation and allergic responses. J Immunol 179: 740-743.
43. Odom S, Gomez G, Kovarova M, Furumoto Y, Ryan JJ, et al. (2004) Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase. J Exp Med 199: 1491-1502. (Pubitemid 38780404)
44. Barbu EA, Zhang J, Siraganian RP (2010) The limited contribution of Fyn and Gab2 to the high affinity IgE receptor signaling in mast cells. J Biol Chem 285: 15761-15768.
45. Kim EK, Choi EJ (2010) Pathological roles of MAPK signaling pathways in human diseases. Biochim Biophys Acta 1802: 396-405.
46. Bentley JK, Hershenson MB (2008) Airway smooth muscle growth in asthma: proliferation, hypertrophy, and migration. Proc Am Thorac Soc 5: 89-96.
47. Huang C, Jacobson K, Schaller MD (2004) MAP kinases and cell migration. J Cell Sci 117: 4619-4628. (Pubitemid 39433429)
48. Kavurma MM, Khachigian LM (2003) ERK, JNK, and p38 MAP kinases differentially regulate proliferation and migration of phenotypically distinct smooth muscle cell subtypes. J Cell Biochem 89: 289-300. (Pubitemid 36547263)
49. Han YJ, Hu WY, Chernaya O, Antic N, Gu L, et al. (2006) Increased myosin light chain kinase expression in hypertension: Regulation by serum response factor via an insertion mutation in the promoter. Mol Biol Cell 17: 4039-4050. (Pubitemid 44330886)
50. Zhou X, Liu Y, You J, Zhang H, Zhang X, et al. (2008) Myosin light-chain kinase contributes to the proliferation and migration of breast cancer cells through cross-talk with activated ERK1/2. Cancer Lett 270: 312-327.
51. Rossi JL, Ralay Ranaivo H, Patel F, Chrzaszcz M, Venkatesan C, et al. (2011) Albumin causes increased myosin light chain kinase expression in astrocytes via p38 mitogen-activated protein kinase. J Neurosci Res 89: 852-861.
52. Zuyderduyn S, Sukkar MB, Fust A, Dhaliwal S, Burgess JK (2008) Treating asthma means treating airway smooth muscle cells. Eur Respir J 32: 265-274.
53. Li H, Chehade M, Liu W, Xiong H, Mayer L, et al. (2007) Allergen-IgE complexes trigger CD23-dependent CCL20 release from human intestinal epithelial cells. Gastroenterology 133: 1905-1915. (Pubitemid 350180817)
54. Kimata M, Inagaki N, Kato T, Miura T, Serizawa I, et al. (2000) Roles of mitogen-activated protein kinase pathways for mediator release from human cultured mast cells. Biochem Pharmacol 60: 589-594. (Pubitemid 30389626)
55. Garrington TP, Ishizuka T, Papst PJ, Chayama K, Webb S, et al. (2000) MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells. EMBO J 19: 5387-5395.
56. Miura K, MacGlashan DW (2000) Phosphatidylinositol-3 kinase regulates p21ras activation during IgE-mediated stimulation of human basophils. Blood 96: 2199-2205.
57. Sly LM, Kalesnikoff J, Lam V, Wong D, Song C, et al. (2008) IgE-induced mast cell survival requires the prolonged generation of reactive oxygen species. J Immunol 181: 3850-3860.
58. Ding HL, Ryder JW, Stull JT, Kamm KE (2009) Signaling processes for initiating smooth muscle contraction upon neural stimulation. J Biol Chem 284: 15541-15548.