The membrane-proximal part of FcεRIα contributes to human IgE and antibody binding - Implications for a general structural motif in Fc receptors

FEBS Letters

Volumn 441, Issue 2, 1998, Pages 225-230

  Nechansky, Andreas ^a   Aschauer, Heinrich ^a   Kricek, Franz ^a  

^a Novartis Forschungsinstitut GmbH   (Austria)

Author keywords

Alanine substitution mutagenesis; Epitope mapping; Homology alignment; Human high affinity IgE receptor; IgE binding site

Indexed keywords

EPITOPE; FC RECEPTOR; IMMUNOGLOBULIN E; MONOCLONAL ANTIBODY; RECEPTOR ANTIBODY;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CELL STRAIN COS1; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; HYPERSENSITIVITY REACTION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; CELLS, CULTURED; COS CELLS; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; HUMANS; IMMUNOGLOBULIN E; INSECTS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, IGE; SEQUENCE HOMOLOGY, AMINO ACID;

BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 0032428035     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)01558-0     Document Type: Article

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