Prediction and experimental characterization of nsSNPs altering human PDZ-binding motifs

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Gfeller, David ^a,b   Ernst, Andreas ^a,d   Jarvik, Nick ^a   Sidhu, Sachdev S ^a   Bader, Gary D ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c UNIVERSITY OF TORONTO   (Canada)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; PCDHA1 PROTEIN; UNCLASSIFIED DRUG; PROTEIN; PROTEIN BINDING;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEASIBILITY STUDY; GENETIC ANALYSIS; GENETIC CONSERVATION; HUMAN; MATHEMATICAL ANALYSIS; MOLECULAR RECOGNITION; NON SYNONYMOUS SINGLE NUCLEOTIDE POLYMORPHISM; PDZ DOMAIN; PREDICTION; PROTEIN PROTEIN INTERACTION; SINGLE NUCLEOTIDE POLYMORPHISM; STOP CODON; VALIDATION PROCESS; AMINO ACID SEQUENCE; CHEMISTRY; GENETIC DATABASE; GENETICS; HUMAN GENOME; MOLECULAR GENETICS; STATISTICAL MODEL;

AMINO ACID SEQUENCE; BINDING SITES; DATABASES, GENETIC; GENOME, HUMAN; HUMANS; MODELS, STATISTICAL; MOLECULAR SEQUENCE DATA; PDZ DOMAINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTEINS;

EID: 84899497681     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094507     Document Type: Article

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