CXCL12 in astrocytes contributes to bone cancer pain through CXCR4-mediated neuronal sensitization and glial activation in rat spinal cord

Journal of Neuroinflammation

Volumn 11, Issue , 2014, Pages

  Shen, Wen ^a   Hu, Xue Ming ^a   Liu, Yan Nan ^a   Han, Yuan ^a   Chen, Li Ping ^a   Wang, Chen Chen ^a   Song, Chao ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Astrocytes; Bone cancer pain; Chemokine; CXCL12; CXCR4; Microglia; Neurons; Spinal cord

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CELL PROTEIN; CHEMOKINE RECEPTOR CXCR4; FLUOROCITRIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; PLERIXAFOR; PROTEIN C FOS; PROTEIN IBA1; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG; CXCR4 PROTEIN, RAT;

ADULT; ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BONE CANCER; CANCER PAIN; CELL ACTIVATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GLIA CELL; HYPERALGESIA; IMMUNOFLUORESCENCE TEST; LATENT PERIOD; MECHANICAL STIMULATION; NOCICEPTION; NONHUMAN; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL GANGLION; THERMAL STIMULATION; TIBIA; WESTERN BLOTTING; ANALYSIS OF VARIANCE; ANIMAL; BONE TUMOR; CARCINOMA; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; METABOLISM; NERVE CELL; PAIN; PATHOLOGY; SPRAGUE DAWLEY RAT; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; ASTROCYTES; BONE NEOPLASMS; CARCINOMA; CHEMOKINE CXCL12; DISEASE MODELS, ANIMAL; FEMALE; HYPERALGESIA; NEURONS; PAIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CXCR4; SPINAL CORD; UP-REGULATION;

EID: 84899481968     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-11-75     Document Type: Article

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