The analgesic effect of low dose focal irradiation in a mouse model of bone cancer is associated with spinal changes in neuro-mediators of nociception

Pain

Volumn 120, Issue 1-2, 2006, Pages 188-201

  Vit, Jean Philippe ^a   Ohara, Peter T ^a   Tien, Duc A ^a   Fike, John R ^a   Eikmeier, Laura ^b   Beitz, Alvin ^b   Wilcox, George L ^b   Jasmin, Luc ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

COX 2; Glia; Ketorolac; Morphine; Osteosarcoma; Pain

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CYCLOOXYGENASE 2; DYNORPHIN; KETOROLAC; MONOCYTE CHEMOTACTIC PROTEIN 1; MORPHINE; PROSTAGLANDIN SYNTHASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BONE CANCER; BONE METABOLISM; CANCER GROWTH; CELL ACTIVITY; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GAMMA RADIATION; IMMUNOHISTOCHEMISTRY; IRRADIATION; MICROGLIA; MOUSE; NOCICEPTION; NONHUMAN; OSTEOCLAST; OSTEOSARCOMA; PAIN ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; ROTAROD TEST;

ANALGESIA; ANALGESICS, OPIOID; ANIMALS; ANTINEOPLASTIC AGENTS; BEHAVIOR, ANIMAL; BONE NEOPLASMS; CHEMOTHERAPY, ADJUVANT; CYTOKINES; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; FEMALE; KETOROLAC; MICE; MICE, INBRED C3H; MORPHINE; NEUROTRANSMITTER AGENTS; PAIN; RADIOTHERAPY DOSAGE; SPINAL CORD; TREATMENT OUTCOME;

EID: 30444459482     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2005.10.033     Document Type: Article

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