Phospholipase Cβ3 in mouse and human dorsal root ganglia and spinal cord is a possible target for treatment of neuropathic pain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 50, 2008, Pages 20004-20008

  Shi, Tie Jun Sten ^a   Liu, Su Xing Leslie ^a   Hammarberg, Henrik ^a   Watanabe, Masahiko ^b   Xu, Zhi Qing David ^a   Hökfelt, Tomas ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Galanin receptor 2; Nerve injury; Neuropeptide; Pain treatment; Sensory neuron

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; PHOSPHOLIPASE C BETA3; 1 (6 ((3 METHOXYESTRA 1,3,5(10) TRIEN 17 YL)AMINO)HEXYL) 1H PYRROLE 2,5 DIONE; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; ESTRANE DERIVATIVE; PHOSPHODIESTERASE INHIBITOR; PHOSPHOLIPASE C BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; MALE; MOUSE; NERVE CELL; NERVE INJURY; NEUROPATHIC PAIN; NONHUMAN; PAIN THRESHOLD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE DRUG DOSE; SPINAL CORD; SPINAL GANGLION; ANIMAL; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; HYPERALGESIA; INJURY; MOUSE MUTANT; PAIN; SPINAL CORD INJURY;

ANIMALIA;

ANIMALS; DISEASE MODELS, ANIMAL; ESTRENES; GANGLIA, SPINAL; HUMANS; HYPERALGESIA; MICE; MICE, MUTANT STRAINS; PAIN; PAIN THRESHOLD; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPASE C BETA; PYRROLIDINONES; SPINAL CORD; SPINAL CORD INJURIES;

EID: 58149399329     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0810899105     Document Type: Article

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