Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway

Cardiovascular Diabetology

Volumn 13, Issue 1, 2014, Pages

  Dou, Jianxin ^a   Li, Huating ^a   Ma, Xiaojing ^a   Zhang, Mingliang ^a   Fang, Qichen ^a   Nie, Meiyun ^a   Bao, Yuqian ^a   Jia, Weiping ^a  

^a SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

Author keywords

ApoE knockout mice; Atherosclerosis; Endothelium dependent relaxation; Metabolic syndrome; Osteocalcin; PI3K Akt eNOS signaling pathway

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; APOLIPOPROTEIN E; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; OSTEOCALCIN; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA STRIP; ARTICLE; ATHEROSCLEROSIS; BLOOD PRESSURE MEASUREMENT; BLOOD SAMPLING; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ENDOTHELIAL DYSFUNCTION; EX VIVO STUDY; GENE INACTIVATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; HUMAN; HUMAN CELL; INSULIN RELEASE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPID BLOOD LEVEL; LIPID DIET; LIPID METABOLISM; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; RISK REDUCTION; SYSTOLIC BLOOD PRESSURE; THORACIC AORTA; UMBILICAL VEIN ENDOTHELIAL CELL; VASODILATATION;

ANIMALS; APOLIPOPROTEINS E; CELLS, CULTURED; DIET, HIGH-FAT; ENDOTHELIUM, VASCULAR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE TYPE III; ORGAN CULTURE TECHNIQUES; OSTEOCALCIN; PROTO-ONCOGENE PROTEINS C-AKT; RANDOM ALLOCATION; SIGNAL TRANSDUCTION; VASODILATION;

EID: 84899478955     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-13-74     Document Type: Article

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