Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles

Respiratory Research

Volumn 15, Issue 1, 2014, Pages

  Parnia, Sam ^a   Hamilton, Lynnsey M ^a   Puddicombe, Sarah M ^a   Holgate, Stephen T ^a   Frew, Anthony J ^a   Davies, Donna E ^a,b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Air pollution; Epidermal growth factor receptor; Inflammation; Interleukin 8; Ligand shedding; Neutrophilia; Transactivation

Indexed keywords

AMPHIREGULIN; CARBON; CIGARETTE SMOKE; EPIDERMAL GROWTH FACTOR RECEPTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; INTERLEUKIN 8; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; NEUTRALIZING ANTIBODY; TRANSFORMING GROWTH FACTOR ALPHA; AUTACOID; EGFR PROTEIN, HUMAN; LIGAND;

ADULT; ARTICLE; AUTOCRINE EFFECT; CELL COUNT; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; EXHAUST GAS; FEMALE; FIBEROPTIC BRONCHOSCOPY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; LIGAND BINDING; MALE; NORMAL HUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION; WESTERN BLOTTING; BIOSYNTHESIS; CELL CULTURE; CELL SURVIVAL; DRUG EFFECT; METABOLISM; MIDDLE AGED; PHYSIOLOGY; RESPIRATORY TRACT MUCOSA; YOUNG ADULT;

ADULT; AUTOCRINE COMMUNICATION; CELL SURVIVAL; CELLS, CULTURED; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-8; LIGANDS; MALE; MIDDLE AGED; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY MUCOSA; VEHICLE EMISSIONS; YOUNG ADULT;

EID: 84899477880     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-15-22     Document Type: Article

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