Transient induction of TGF-α disrupts lung morphogenesis, causing pulmonary disease in adulthood

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 287, Issue 4 31-4, 2004, Pages

  Le Cras, T D ^a,c   Hardie, W D ^a   Deutsch, G H ^a   Albertine, K H ^b   Ikegami, M ^a   Whitsett, J A ^a   Korfhagen, T R ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Bronchopulmonary dysplasia; Epidermal growth factor receptor; Lung remodeling; Neonatal lung development; Pulmonary hypertension

Indexed keywords

ELASTIN; EPIDERMAL GROWTH FACTOR RECEPTOR; SURFACTANT PROTEIN C; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; BODY WEIGHT; CAPILLARY ENDOTHELIUM; CONTROLLED STUDY; ELECTRON MICROSCOPY; ERYTHROCYTE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY CELL; LUNG ALVEOLUS WALL; LUNG BLOOD VESSEL; LUNG COMPLIANCE; LUNG DISEASE; LUNG DYSPLASIA; LUNG FIBROSIS; LUNG FUNCTION; LUNG STRUCTURE; LUNG VOLUME; MACROPHAGE; MORPHOGENESIS; MOUSE; NEUTROPHIL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; STAINING; TRANSGENIC MOUSE;

ANIMALS; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LUNG; LUNG DISEASES; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; MORPHOGENESIS; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 4544297128     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00084.2004     Document Type: Article

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