-
1
-
-
79953229234
-
Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells
-
Antonyak M.A., Li B., Boroughs L.K., Johnson J.L., Druso J.E., et al. Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:4852-4857.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 4852-4857
-
-
Antonyak, M.A.1
Li, B.2
Boroughs, L.K.3
Johnson, J.L.4
Druso, J.E.5
-
2
-
-
57749099102
-
P53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest
-
Braun C.J., Zhang X., Savelyeva I., Wolff S., Moll U.M., et al. p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest. Cancer Res. 2008, 68:10094-10104.
-
(2008)
Cancer Res.
, vol.68
, pp. 10094-10104
-
-
Braun, C.J.1
Zhang, X.2
Savelyeva, I.3
Wolff, S.4
Moll, U.M.5
-
3
-
-
62549155841
-
Monocyte chemotactic protein 1 promotes lung cancer-induced bone resorptive lesions invivo
-
Cai Z., Chen Q., Chen J., Lu Y., Xiao G., et al. Monocyte chemotactic protein 1 promotes lung cancer-induced bone resorptive lesions invivo. Neoplasia 2009, 11:228-236.
-
(2009)
Neoplasia
, vol.11
, pp. 228-236
-
-
Cai, Z.1
Chen, Q.2
Chen, J.3
Lu, Y.4
Xiao, G.5
-
4
-
-
78651405675
-
PDGFR signaling blockade in marrow stroma impairs lung Cancer bone metastasis
-
Catena R., Luis-Ravelo D., Anton I., Zandueta C., Salazar-Colocho P., et al. PDGFR signaling blockade in marrow stroma impairs lung Cancer bone metastasis. Cancer Res. 2011, 71:164-174.
-
(2011)
Cancer Res.
, vol.71
, pp. 164-174
-
-
Catena, R.1
Luis-Ravelo, D.2
Anton, I.3
Zandueta, C.4
Salazar-Colocho, P.5
-
5
-
-
77955744282
-
Anti-placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation
-
Coenegrachts L., Maes C., Torrekens S., Van Looveren R., Mazzone M., et al. Anti-placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation. Cancer Res. 2010, 70:6537-6547.
-
(2010)
Cancer Res.
, vol.70
, pp. 6537-6547
-
-
Coenegrachts, L.1
Maes, C.2
Torrekens, S.3
Van Looveren, R.4
Mazzone, M.5
-
6
-
-
0030749321
-
Skeletal complications of malignancy
-
Coleman R.E. Skeletal complications of malignancy. Cancer 1997, 80:1588-1594.
-
(1997)
Cancer
, vol.80
, pp. 1588-1594
-
-
Coleman, R.E.1
-
7
-
-
22144461002
-
MiRNAs, cancer, and stem cell division
-
Croce C.M., Calin G.A. miRNAs, cancer, and stem cell division. Cell 2005, 122:6-7.
-
(2005)
Cell
, vol.122
, pp. 6-7
-
-
Croce, C.M.1
Calin, G.A.2
-
8
-
-
80055080741
-
MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells
-
Feng S., Cong S., Zhang X., Bao X., Wang W., et al. MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells. Nucleic Acids Res. 2011, 39:6669-6678.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 6669-6678
-
-
Feng, S.1
Cong, S.2
Zhang, X.3
Bao, X.4
Wang, W.5
-
9
-
-
0038481970
-
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited
-
Fidler I.J. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat. Rev. Cancer 2003, 3:453-458.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 453-458
-
-
Fidler, I.J.1
-
10
-
-
0031760355
-
The amount and proteolytic content of vesicles shed by human cancer cell lines correlates with their invitro invasiveness
-
Ginestra A., La Placa M.D., Saladino F., Cassara D., Nagase H., et al. The amount and proteolytic content of vesicles shed by human cancer cell lines correlates with their invitro invasiveness. Anticancer Res. 1998, 18:3433-3437.
-
(1998)
Anticancer Res.
, vol.18
, pp. 3433-3437
-
-
Ginestra, A.1
La Placa, M.D.2
Saladino, F.3
Cassara, D.4
Nagase, H.5
-
11
-
-
79960960417
-
Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche
-
Grange C., Tapparo M., Collino F., Vitillo L., Damasco C., et al. Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res. 2011, 71:5346-5356.
-
(2011)
Cancer Res.
, vol.71
, pp. 5346-5356
-
-
Grange, C.1
Tapparo, M.2
Collino, F.3
Vitillo, L.4
Damasco, C.5
-
12
-
-
10144241022
-
Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis
-
Guise T.A., Yin J.J., Taylor S.D., Kumagai Y., Dallas M., et al. Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. J.Clin. Invest. 1996, 98:1544-1549.
-
(1996)
J.Clin. Invest.
, vol.98
, pp. 1544-1549
-
-
Guise, T.A.1
Yin, J.J.2
Taylor, S.D.3
Kumagai, Y.4
Dallas, M.5
-
13
-
-
79957879331
-
Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis
-
Hood J.L., San R.S., Wickline S.A. Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis. Cancer Res. 2011, 71:3792-3801.
-
(2011)
Cancer Res.
, vol.71
, pp. 3792-3801
-
-
Hood, J.L.1
San, R.S.2
Wickline, S.A.3
-
14
-
-
33947508102
-
Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury
-
Hristov M., Zernecke A., Bidzhekov K., Liehn E.A., Shagdarsuren E., et al. Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury. Circ. Res. 2007, 100:590-597.
-
(2007)
Circ. Res.
, vol.100
, pp. 590-597
-
-
Hristov, M.1
Zernecke, A.2
Bidzhekov, K.3
Liehn, E.A.4
Shagdarsuren, E.5
-
15
-
-
28444469246
-
Silencing of microRNAs invivo with 'antagomirs'
-
Krutzfeldt J., Rajewsky N., Braich R., Rajeev K.G., Tuschl T., et al. Silencing of microRNAs invivo with 'antagomirs'. Nature 2005, 438:685-689.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
-
16
-
-
34247593034
-
Impaired microRNA processing enhances cellular transformation and tumorigenesis
-
Kumar M.S., Lu J., Mercer K.L., Golub T.R., Jacks T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat. Genet. 2007, 39:673-677.
-
(2007)
Nat. Genet.
, vol.39
, pp. 673-677
-
-
Kumar, M.S.1
Lu, J.2
Mercer, K.L.3
Golub, T.R.4
Jacks, T.5
-
17
-
-
79751473114
-
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu C., Kelnar K., Liu B., Chen X., Calhoun-Davis T., et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat. Med. 2011, 17:211-215.
-
(2011)
Nat. Med.
, vol.17
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
Chen, X.4
Calhoun-Davis, T.5
-
18
-
-
85064773354
-
A gene signature of bone metastatic colonization sensitizes for tumor-induced osteolysis and predicts survival in lung cancer
-
in press.
-
Luis-Ravelo D., Anton I., Zandueta C., Valencia K., Ormazabal C., et al. A gene signature of bone metastatic colonization sensitizes for tumor-induced osteolysis and predicts survival in lung cancer. Oncogene 2013, in press.
-
(2013)
Oncogene
-
-
Luis-Ravelo, D.1
Anton, I.2
Zandueta, C.3
Valencia, K.4
Ormazabal, C.5
-
19
-
-
84894356774
-
RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner
-
in press.
-
Luis-Ravelo D., Anton I., Zandueta C., Valencia K., Pajares M.J., et al. RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner. Mol. Oncol. 2013, in press.
-
(2013)
Mol. Oncol.
-
-
Luis-Ravelo, D.1
Anton, I.2
Zandueta, C.3
Valencia, K.4
Pajares, M.J.5
-
20
-
-
35148886434
-
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
-
Ma L., Teruya-Feldstein J., Weinberg R.A. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007, 449:682-688.
-
(2007)
Nature
, vol.449
, pp. 682-688
-
-
Ma, L.1
Teruya-Feldstein, J.2
Weinberg, R.A.3
-
21
-
-
65249179023
-
CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex
-
Martin D., Galisteo R., Gutkind J.S. CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex. J.Biol. Chem. 2009, 284:6038-6042.
-
(2009)
J.Biol. Chem.
, vol.284
, pp. 6038-6042
-
-
Martin, D.1
Galisteo, R.2
Gutkind, J.S.3
-
22
-
-
84862908547
-
Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
-
Montecalvo A., Larregina A.T., Shufesky W.J., Stolz D.B., Sullivan M.L., et al. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood 2012, 119:756-766.
-
(2012)
Blood
, vol.119
, pp. 756-766
-
-
Montecalvo, A.1
Larregina, A.T.2
Shufesky, W.J.3
Stolz, D.B.4
Sullivan, M.L.5
-
23
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Muller A., Homey B., Soto H., Ge N., Catron D., et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001, 410:50-56.
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
-
24
-
-
0036675220
-
Metastasis to bone: causes, consequences and therapeutic opportunities
-
Mundy G.R. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat. Rev. Cancer 2002, 2:584-593.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
25
-
-
34247269026
-
Genetic determinants of cancer metastasis
-
Nguyen D.X., Massague J. Genetic determinants of cancer metastasis. Nat. Rev. Genet. 2007, 8:341-352.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 341-352
-
-
Nguyen, D.X.1
Massague, J.2
-
26
-
-
77953142134
-
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes
-
Park J.E., Tan H.S., Datta A., Lai R.C., Zhang H., et al. Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol. Cell Proteomics 2010, 9:1085-1099.
-
(2010)
Mol. Cell Proteomics
, vol.9
, pp. 1085-1099
-
-
Park, J.E.1
Tan, H.S.2
Datta, A.3
Lai, R.C.4
Zhang, H.5
-
27
-
-
84862007577
-
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
-
Peinado H., Aleckovic M., Lavotshkin S., Matei I., Costa-Silva B., et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat. Med. 2012, 18(6):883-891.
-
(2012)
Nat. Med.
, vol.18
, Issue.6
, pp. 883-891
-
-
Peinado, H.1
Aleckovic, M.2
Lavotshkin, S.3
Matei, I.4
Costa-Silva, B.5
-
28
-
-
77957936826
-
Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development
-
Pichiorri F., Suh S.S., Rocci A., De Luca L., Taccioli C., et al. Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development. Cancer Cell 2010, 18:367-381.
-
(2010)
Cancer Cell
, vol.18
, pp. 367-381
-
-
Pichiorri, F.1
Suh, S.S.2
Rocci, A.3
De Luca, L.4
Taccioli, C.5
-
29
-
-
84855813448
-
A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells
-
Png K.J., Halberg N., Yoshida M., Tavazoie S.F. A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells. Nature 2012, 481:190-194.
-
(2012)
Nature
, vol.481
, pp. 190-194
-
-
Png, K.J.1
Halberg, N.2
Yoshida, M.3
Tavazoie, S.F.4
-
30
-
-
67949097489
-
Exosomes-vesicular carriers for intercellular communication
-
Simons M., Raposo G. Exosomes-vesicular carriers for intercellular communication. Curr. Opin. Cell Biol. 2009, 21:575-581.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 575-581
-
-
Simons, M.1
Raposo, G.2
-
31
-
-
57049103401
-
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
-
Skog J., Wurdinger T., van Rijn S., Meijer D.H., Gainche L., et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat. Cell Biol. 2008, 10:1470-1476.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1470-1476
-
-
Skog, J.1
Wurdinger, T.2
van Rijn, S.3
Meijer, D.H.4
Gainche, L.5
-
32
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
Tavazoie S.F., Alarcon C., Oskarsson T., Padua D., Wang Q., et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008, 451:147-152.
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
Alarcon, C.2
Oskarsson, T.3
Padua, D.4
Wang, Q.5
-
33
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi H., Ekstrom K., Bossios A., Sjostrand M., Lee J.J., et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 2007, 9:654-659.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekstrom, K.2
Bossios, A.3
Sjostrand, M.4
Lee, J.J.5
-
34
-
-
84857093651
-
Inhibition of collagen receptor Discoidin Domain Receptor-1 (DDR1) reduces cell survival, homing, and colonization in lung Cancer bone metastasis
-
Valencia K., Ormazabal C., Zandueta C., Luis-Ravelo D., Anton I., et al. Inhibition of collagen receptor Discoidin Domain Receptor-1 (DDR1) reduces cell survival, homing, and colonization in lung Cancer bone metastasis. Clin. Cancer Res. 2012, 18:969-980.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 969-980
-
-
Valencia, K.1
Ormazabal, C.2
Zandueta, C.3
Luis-Ravelo, D.4
Anton, I.5
-
35
-
-
84870390937
-
MiR-326 associates with biochemical markers of bone turnover in lung cancer bone metastasis
-
Valencia K., Martin-Fernandez M., Zandueta C., Ormazabal C., Martinez-Canarias S., et al. miR-326 associates with biochemical markers of bone turnover in lung cancer bone metastasis. Bone 2013, 52:532-539.
-
(2013)
Bone
, vol.52
, pp. 532-539
-
-
Valencia, K.1
Martin-Fernandez, M.2
Zandueta, C.3
Ormazabal, C.4
Martinez-Canarias, S.5
-
36
-
-
42049090140
-
A novel lung cancer signature mediates metastatic bone colonization by a dual mechanism
-
Vicent S., Luis-Ravelo D., Anton I., Garcia-Tunon I., Borras-Cuesta F., et al. A novel lung cancer signature mediates metastatic bone colonization by a dual mechanism. Cancer Res. 2008, 68:2275-2285.
-
(2008)
Cancer Res.
, vol.68
, pp. 2275-2285
-
-
Vicent, S.1
Luis-Ravelo, D.2
Anton, I.3
Garcia-Tunon, I.4
Borras-Cuesta, F.5
-
38
-
-
0032918414
-
TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
-
Yin J.J., Selander K., Chirgwin J.M., Dallas M., Grubbs B.G., et al. TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J.Clin. Invest. 1999, 103:197-206.
-
(1999)
J.Clin. Invest.
, vol.103
, pp. 197-206
-
-
Yin, J.J.1
Selander, K.2
Chirgwin, J.M.3
Dallas, M.4
Grubbs, B.G.5
-
39
-
-
77955516533
-
Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers
-
Yu L., Todd N.W., Xing L., Xie Y., Zhang H., et al. Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers. Int. J. Cancer 2010, 127:2870-2878.
-
(2010)
Int. J. Cancer
, vol.127
, pp. 2870-2878
-
-
Yu, L.1
Todd, N.W.2
Xing, L.3
Xie, Y.4
Zhang, H.5
-
40
-
-
67649311599
-
Latent bone metastasis in breast cancer tied to Src-dependent survival signals
-
Zhang X.H., Wang Q., Gerald W., Hudis C.A., Norton L., et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell 2009, 16:67-78.
-
(2009)
Cancer Cell
, vol.16
, pp. 67-78
-
-
Zhang, X.H.1
Wang, Q.2
Gerald, W.3
Hudis, C.A.4
Norton, L.5
-
41
-
-
77951631347
-
Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth
-
Zhang J., Lu Y., Pienta K.J. Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth. J.Natl. Cancer Inst. 2010, 102:522-528.
-
(2010)
J.Natl. Cancer Inst.
, vol.102
, pp. 522-528
-
-
Zhang, J.1
Lu, Y.2
Pienta, K.J.3
|