-
1
-
-
0036674501
-
Dissemination and growth of cancer cells in metastatic sites
-
Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002;2:563-72.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 563-572
-
-
Chambers, A.F.1
Groom, A.C.2
MacDonald, I.C.3
-
2
-
-
0038481970
-
The pathogenesis of cancer metastasis: The "seed and soil" hypothesis revisited
-
Fidler IJ. The pathogenesis of cancer metastasis: the "seed and soil" hypothesis revisited. Nat Rev Cancer 2003;3:453-8.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 453-458
-
-
Fidler, I.J.1
-
3
-
-
0030749321
-
Skeletal complications of malignancy
-
Coleman RE. Skeletal complications of malignancy. Cancer 1997;80:1588-94.
-
(1997)
Cancer
, vol.80
, pp. 1588-1594
-
-
Coleman, R.E.1
-
4
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
Joyce JA, Pollard JW. Microenvironmental regulation of metastasis. Nat Rev Cancer 2009;9:239-52.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
5
-
-
50549121134
-
The distribution of secondary growths in cancer of the breast
-
Paget S. The distribution of secondary growths in cancer of the breast. Lancet 1889;1:571-3.
-
(1889)
Lancet
, vol.1
, pp. 571-573
-
-
Paget, S.1
-
6
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002;2:584-93.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
7
-
-
10144241022
-
Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis
-
Guise TA, Yin JJ, Taylor SD, Kumagai Y, Dallas M, Boyce BF, et al. Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. J Clin Invest 1996;98:1544-9.
-
(1996)
J Clin Invest
, vol.98
, pp. 1544-1549
-
-
Guise, T.A.1
Yin, J.J.2
Taylor, S.D.3
Kumagai, Y.4
Dallas, M.5
Boyce, B.F.6
-
8
-
-
0037025352
-
Transforming growth factor-beta stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways
-
Kakonen SM, Selander KS, Chirgwin JM, Yin JJ, Burns S, Rankin WA, et al. Transforming growth factor-beta stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways. J Biol Chem 2002;277:24571-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 24571-24578
-
-
Kakonen, S.M.1
Selander, K.S.2
Chirgwin, J.M.3
Yin, J.J.4
Burns, S.5
Rankin, W.A.6
-
9
-
-
19644378914
-
Mechanisms of cancer metastasis to the bone
-
Yin JJ, Pollock CB, Kelly K, Kakonen SM, Selander KS, Chirgwin JM, et al. Mechanisms of cancer metastasis to the bone. Cell Res 2005;15:57-62.
-
(2005)
Cell Res
, vol.15
, pp. 57-62
-
-
Yin, J.J.1
Pollock, C.B.2
Kelly, K.3
Kakonen, S.M.4
Selander, K.S.5
Chirgwin, J.M.6
-
10
-
-
0032918414
-
TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
-
Yin JJ, Selander K, Chirgwin JM, Dallas M, Grubbs BG, Wieser R, et al. TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J Clin Invest 1999;103:197-206.
-
(1999)
J Clin Invest
, vol.103
, pp. 197-206
-
-
Yin, J.J.1
Selander, K.2
Chirgwin, J.M.3
Dallas, M.4
Grubbs, B.G.5
Wieser, R.6
-
11
-
-
42049090140
-
A novel lung cancer signature mediates metastatic bone colonization by a dual mechanism
-
Vicent S, Luis-Ravelo D, Anton I, Garcia-Tunon I, Borras-Cuesta F, Dotor J, et al. A novel lung cancer signature mediates metastatic bone colonization by a dual mechanism. Cancer Res 2008;68:2275-85.
-
(2008)
Cancer Res
, vol.68
, pp. 2275-2285
-
-
Vicent, S.1
Luis-Ravelo, D.2
Anton, I.3
Garcia-Tunon, I.4
Borras-Cuesta, F.5
Dotor, J.6
-
12
-
-
34247269026
-
Genetic determinants of cancer metastasis
-
Nguyen DX, Massague J. Genetic determinants of cancer metastasis. Nat Rev Genet 2007;8:341-52.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 341-352
-
-
Nguyen, D.X.1
Massague, J.2
-
13
-
-
58149214627
-
Involvement of cell-cell and cell-matrix interactions in bone destruction induced by metastatic MDA-MB-231 human breast cancer cells in nude mice
-
Nakamura H, Hiraga T, Ninomiya T, Hosoya A, Fujisaki N, Yoneda T, et al. Involvement of cell-cell and cell-matrix interactions in bone destruction induced by metastatic MDA-MB-231 human breast cancer cells in nude mice. J Bone Miner Metab 2008;26:642-7.
-
(2008)
J Bone Miner Metab
, vol.26
, pp. 642-647
-
-
Nakamura, H.1
Hiraga, T.2
Ninomiya, T.3
Hosoya, A.4
Fujisaki, N.5
Yoneda, T.6
-
14
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001;410:50-6.
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
-
15
-
-
0036829305
-
Role of the bone marrow microenvironment in multiple myeloma
-
Roodman GD. Role of the bone marrow microenvironment in multiple myeloma. J Bone Miner Res 2002;17:1921-5.
-
(2002)
J Bone Miner Res
, vol.17
, pp. 1921-1925
-
-
Roodman, G.D.1
-
16
-
-
4644261592
-
Mechanisms of bone metastasis
-
Roodman GD. Mechanisms of bone metastasis. N Engl J Med 2004;350:1655-64.
-
(2004)
N Engl J Med
, vol.350
, pp. 1655-1664
-
-
Roodman, G.D.1
-
17
-
-
34548316976
-
Molecular basis for sunitinib efficacy and future clinical development
-
Faivre S, Demetri G, Sargent W, Raymond E. Molecular basis for sunitinib efficacy and future clinical development. Nat Rev Drug Discov 2007;6:734-45.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 734-745
-
-
Faivre, S.1
Demetri, G.2
Sargent, W.3
Raymond, E.4
-
19
-
-
0142092593
-
Role of c-kit/Kit ligand signaling in regulating vasculogenesis
-
Heissig B, Werb Z, Rafii S, Hattori K. Role of c-kit/Kit ligand signaling in regulating vasculogenesis. Thromb Haemost 2003;90:570-6.
-
(2003)
Thromb Haemost
, vol.90
, pp. 570-576
-
-
Heissig, B.1
Werb, Z.2
Rafii, S.3
Hattori, K.4
-
21
-
-
60849138787
-
Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells
-
Hooper AT, Butler JM, Nolan DJ, Kranz A, Iida K, Kobayashi M, et al. Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell 2009;4:263-74.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 263-274
-
-
Hooper, A.T.1
Butler, J.M.2
Nolan, D.J.3
Kranz, A.4
Iida, K.5
Kobayashi, M.6
-
22
-
-
0038665460
-
Double target for tumor mass destruction
-
Saharinen P, Alitalo K. Double target for tumor mass destruction. J Clin Invest 2003;111:1277-80.
-
(2003)
J Clin Invest
, vol.111
, pp. 1277-1280
-
-
Saharinen, P.1
Alitalo, K.2
-
23
-
-
0035958030
-
Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells
-
Lai CF, Chaudhary L, Fausto A, Halstead LR, Ory DS, Avioli LV, et al. Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells. J Biol Chem 2001;276:14443-50.
-
(2001)
J Biol Chem
, vol.276
, pp. 14443-14450
-
-
Lai, C.F.1
Chaudhary, L.2
Fausto, A.3
Halstead, L.R.4
Ory, D.S.5
Avioli, L.V.6
-
24
-
-
34548052223
-
EWS/FLI-1 oncoprotein subtypes impose different requirements for transformation and metastatic activity in a murine model
-
Gonzalez I, Vicent S, de Alava E, Lecanda F. EWS/FLI-1 oncoprotein subtypes impose different requirements for transformation and metastatic activity in a murine model. J Mol Med 2007;85:1015-29.
-
(2007)
J Mol Med
, vol.85
, pp. 1015-1029
-
-
Gonzalez, I.1
Vicent, S.2
De Alava, E.3
Lecanda, F.4
-
25
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordon-Cardo C, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003;3:537-49.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordon-Cardo, C.6
-
26
-
-
0026010305
-
Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis
-
Broekelmann TJ, Limper AH, Colby TV, McDonald JA. Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc Natl Acad Sci U S A 1991;88:6642-6.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 6642-6646
-
-
Broekelmann, T.J.1
Limper, A.H.2
Colby, T.V.3
McDonald, J.A.4
-
27
-
-
2442562277
-
A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging
-
Ponomarev V, Doubrovin M, Serganova I, Vider J, Shavrin A, Beresten T, et al. A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging. Eur J Nucl Med Mol Imaging 2004;31:740-51.
-
(2004)
Eur J Nucl Med Mol Imaging
, vol.31
, pp. 740-751
-
-
Ponomarev, V.1
Doubrovin, M.2
Serganova, I.3
Vider, J.4
Shavrin, A.5
Beresten, T.6
-
28
-
-
76249126867
-
Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma
-
Huang D, Ding Y, Li Y, Luo WM, Zhang ZF, Snider J, et al. Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma. Cancer Res 2010;70:1053-62.
-
(2010)
Cancer Res
, vol.70
, pp. 1053-1062
-
-
Huang, D.1
Ding, Y.2
Li, Y.3
Luo, W.M.4
Zhang, Z.F.5
Snider, J.6
-
29
-
-
3543002277
-
VEGF-null cells require PDGFR alpha signaling-mediated stromal fibroblast recruitment for tumorigenesis
-
Dong J, Grunstein J, Tejada M, Peale F, Frantz G, Liang WC, et al. VEGF-null cells require PDGFR alpha signaling-mediated stromal fibroblast recruitment for tumorigenesis. EMBO J 2004;23:2800-10.
-
(2004)
EMBO J
, vol.23
, pp. 2800-2810
-
-
Dong, J.1
Grunstein, J.2
Tejada, M.3
Peale, F.4
Frantz, G.5
Liang, W.C.6
-
30
-
-
33646736321
-
Tumordriven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma
-
Tejada ML, Yu L, Dong J, Jung K, Meng G, Peale FV, et al. Tumordriven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma. Clin Cancer Res 2006;12:2676-88.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2676-2688
-
-
Tejada, M.L.1
Yu, L.2
Dong, J.3
Jung, K.4
Meng, G.5
Peale, F.V.6
-
31
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
Mendel DB, Laird AD, Xin X, Louie SG, Christensen JG, Li G, , et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 2003;9:327-37.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
-
32
-
-
9144274970
-
SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model
-
Murray LJ, Abrams TJ, Long KR, Ngai TJ, Olson LM, Hong W, et al. SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model. Clin Exp Metastasis 2003;20:757-66.
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 757-766
-
-
Murray, L.J.1
Abrams, T.J.2
Long, K.R.3
Ngai, T.J.4
Olson, L.M.5
Hong, W.6
-
33
-
-
33646383590
-
Recent advances in understanding the mechanism of action of bisphosphonates
-
Coxon FP, Thompson K, Rogers MJ. Recent advances in understanding the mechanism of action of bisphosphonates. Curr Opin Pharmacol 2006;6:307-12.
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 307-312
-
-
Coxon, F.P.1
Thompson, K.2
Rogers, M.J.3
-
34
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Vinals F, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009;15:220-31.
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Vinals, F.6
-
35
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos JM, Lee CR, Cruz-Munoz W, Bjarnason GA, Christensen JG, Kerbel RS. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 2009;15:232-9.
-
(2009)
Cancer Cell
, vol.15
, pp. 232-239
-
-
Ebos, J.M.1
Lee, C.R.2
Cruz-Munoz, W.3
Bjarnason, G.A.4
Christensen, J.G.5
Kerbel, R.S.6
-
36
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
Kaplan RN, Riba RD, Zacharoulis S, Takeda T, Okuyama H, Vinals F, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005;438:820-7.
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.N.1
Riba, R.D.2
Zacharoulis, S.3
Takeda, T.4
Okuyama, H.5
Vinals, F.6
-
37
-
-
73949143686
-
Phase II study of sunitinib in recurrent or metastatic squamous cell carcinoma of the head and neck: GORTEC 2006-01
-
Machiels JP, Henry S, Zanetta S, Kaminsky MC, Michoux N, Rommel D, et al. Phase II study of sunitinib in recurrent or metastatic squamous cell carcinoma of the head and neck: GORTEC 2006-01. J Clin Oncol 2010;28:21-8.
-
(2010)
J Clin Oncol
, vol.28
, pp. 21-28
-
-
Machiels, J.P.1
Henry, S.2
Zanetta, S.3
Kaminsky, M.C.4
Michoux, N.5
Rommel, D.6
|