-
1
-
-
38949108241
-
Body-mass index and incidence of cancer: A systematic review and meta-analysis of prospective observational studies
-
A.G. Renehan, M. Tyson, and M. Egger et al. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies Lancet 371 2008 569 578
-
(2008)
Lancet
, vol.371
, pp. 569-578
-
-
Renehan, A.G.1
Tyson, M.2
Egger, M.3
-
2
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Y. Zhang, R. Proenca, and M. Maffei et al. Positional cloning of the mouse obese gene and its human homologue Nature 372 1994 425 432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
-
3
-
-
0032552112
-
The stomach is a source of leptin
-
A. Bado, S. Levasseur, and S. Attoub et al the stomach is a source of leptin Nature 394 1998 790 793
-
(1998)
Nature
, vol.394
, pp. 790-793
-
-
Bado, A.1
Levasseur, S.2
Attoub, S.3
-
4
-
-
0032508682
-
Biological action of leptin as an angiogenic factor
-
M.R. Sierra-Honigmann, A.K. Nath, and C. Murakami et al. Biological action of leptin as an angiogenic factor Science 281 1998 1683 1686
-
(1998)
Science
, vol.281
, pp. 1683-1686
-
-
Sierra-Honigmann, M.R.1
Nath, A.K.2
Murakami, C.3
-
5
-
-
0037146224
-
Leptin - A growth factor in normal and malignant breast cells and for normal mammary gland development
-
X. Hu, S.C. Juneja, and N.J. Maihle et al. Leptin - a growth factor in normal and malignant breast cells and for normal mammary gland development J. Natl Cancer Inst. 94 2002 1704 1711
-
(2002)
J. Natl Cancer Inst.
, vol.94
, pp. 1704-1711
-
-
Hu, X.1
Juneja, S.C.2
Maihle, N.J.3
-
7
-
-
12244271468
-
Expression of leptin receptors and potential effects of leptin on the cell growth and activation of mitogen-activated protein kinases in ovarian cancer cells
-
J.H. Choi, S.H. Park, and P.C.K. Leung et al. Expression of leptin receptors and potential effects of leptin on the cell growth and activation of mitogen-activated protein kinases in ovarian cancer cells J. Clin. Endocrinol. Metab. 90 2005 207 210
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 207-210
-
-
Choi, J.H.1
Park, S.H.2
Leung, P.C.K.3
-
9
-
-
4143118039
-
Molecular mechanisms involved in the growth stimulation of breast cancer cells by leptin
-
N. Yin, D. Wang, and H. Zhang et al. Molecular mechanisms involved in the growth stimulation of breast cancer cells by leptin Cancer Res. 64 2004 5870 5875
-
(2004)
Cancer Res.
, vol.64
, pp. 5870-5875
-
-
Yin, N.1
Wang, D.2
Zhang, H.3
-
10
-
-
0037072868
-
Transcriptional activation of the human leptin gene in response to hypoxia. Involvement of hypoxia-inducible factor 1
-
G. Ambrosini, A.K. Nath, and M. Rocío Sierra-Honigmann et al. Transcriptional activation of the human leptin gene in response to hypoxia. Involvement of hypoxia-inducible factor 1 J. Biol. Chem. 277 2002 34601 34609
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34601-34609
-
-
Ambrosini, G.1
Nath, A.K.2
Rocío Sierra-Honigmann, M.3
-
11
-
-
3042817487
-
Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer
-
M. Ishikawa, J. Kitayama, and H. Nagawa Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer Clin. Cancer Res. 10 2004 4325 4331
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 4325-4331
-
-
Ishikawa, M.1
Kitayama, J.2
Nagawa, H.3
-
12
-
-
5144229540
-
Leptin interferes with the effects of the antiestrogen ICI 182,780 in MCF-7 breast cancer cells
-
C. Garofalo, D. Sisci, and E. Surmacz Leptin interferes with the effects of the antiestrogen ICI 182,780 in MCF-7 breast cancer cells Clin. Cancer Res. 10 2004 6466 6475
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 6466-6475
-
-
Garofalo, C.1
Sisci, D.2
Surmacz, E.3
-
13
-
-
34347392511
-
Cyclo-oxygenase-independent inhibition of apoptosis and stimulation of proliferation by leptin in human colon cancer cells
-
O.O. Ogunwobi, and I.L. Beales Cyclo-oxygenase-independent inhibition of apoptosis and stimulation of proliferation by leptin in human colon cancer cells Dig. Dis. Sci. 52 2007 1934 1945
-
(2007)
Dig. Dis. Sci.
, vol.52
, pp. 1934-1945
-
-
Ogunwobi, O.O.1
Beales, I.L.2
-
14
-
-
80052580981
-
Leptin acts as a growth factor for colorectal tumours at stages subsequent to tumour initiation in murine colon carcinogenesis
-
H. Endo, K. Hosono, and T. Uchiyama et al. Leptin acts as a growth factor for colorectal tumours at stages subsequent to tumour initiation in murine colon carcinogenesis Gut 60 2011 1363 1371
-
(2011)
Gut
, vol.60
, pp. 1363-1371
-
-
Endo, H.1
Hosono, K.2
Uchiyama, T.3
-
15
-
-
0033747214
-
Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, Rho-, and Rac-dependent signaling pathways
-
S. Attoub, V. Noe, and L. Pirola et al. Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, Rho-, and Rac-dependent signaling pathways FASEB J. 14 2000 2329 2338
-
(2000)
FASEB J.
, vol.14
, pp. 2329-2338
-
-
Attoub, S.1
Noe, V.2
Pirola, L.3
-
16
-
-
34248563290
-
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
-
S. Meloche, and J. Pouyssegur The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition Oncogene 26 2007 3227 3239
-
(2007)
Oncogene
, vol.26
, pp. 3227-3239
-
-
Meloche, S.1
Pouyssegur, J.2
-
17
-
-
0036251154
-
Stat proteins and oncogenesis
-
J. Bromberg Stat proteins and oncogenesis J. Clin. Invest. 109 2002 1139 1142
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1139-1142
-
-
Bromberg, J.1
-
19
-
-
0037473051
-
Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK-dependent pathway
-
M. Kanai, Y. Konda, and T. Nakajima et al. Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK-dependent pathway Oncogene 22 2003 548 554
-
(2003)
Oncogene
, vol.22
, pp. 548-554
-
-
Kanai, M.1
Konda, Y.2
Nakajima, T.3
-
20
-
-
70350010461
-
Overweight, obesity and gastric cancer risk: Results from a meta-analysis of cohort studies
-
P. Yang, Y. Zhou, and B. Chen et al. Overweight, obesity and gastric cancer risk: results from a meta-analysis of cohort studies Eur. J. Cancer 45 2009 2867 2873
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 2867-2873
-
-
Yang, P.1
Zhou, Y.2
Chen, B.3
-
21
-
-
33749410599
-
Expression pattern of leptin and leptin receptor (OB-R) in human gastric cancer
-
M. Ishikawa, J. Kitayama, and H. Nagawa Expression pattern of leptin and leptin receptor (OB-R) in human gastric cancer World J. Gastroenterol. 12 2006 5517 5522
-
(2006)
World J. Gastroenterol.
, vol.12
, pp. 5517-5522
-
-
Ishikawa, M.1
Kitayama, J.2
Nagawa, H.3
-
22
-
-
0035103849
-
Leptin mediates a proliferative response in human gastric mucosa cells with functional receptor
-
R. Schneider, S.R. Bornstein, and G.P. Chrousos et al. Leptin mediates a proliferative response in human gastric mucosa cells with functional receptor Horm. Metab. Res. 33 2001 1 6
-
(2001)
Horm. Metab. Res.
, vol.33
, pp. 1-6
-
-
Schneider, R.1
Bornstein, S.R.2
Chrousos, G.P.3
-
23
-
-
13144280875
-
Serum leptin concentration and advanced gastrointestinal cancers: A case controlled study
-
F.F. Bolukbas, H. Kilic, and C. Bolukbas et al. Serum leptin concentration and advanced gastrointestinal cancers: a case controlled study BMC Cancer 4 2004 4
-
(2004)
BMC Cancer
, vol.4
, pp. 4
-
-
Bolukbas, F.F.1
Kilic, H.2
Bolukbas, C.3
-
24
-
-
33644972707
-
Variation in expression of gastric leptin according to differentiation and growth pattern in gastric adenocarcinoma
-
art. no. 29
-
S.J. Hong, K.W. Kwon, and S.G. Kim et al. Variation in expression of gastric leptin according to differentiation and growth pattern in gastric adenocarcinoma Cytokine 33 2006 66 71 art. no. 29
-
(2006)
Cytokine
, vol.33
, pp. 66-71
-
-
Hong, S.J.1
Kwon, K.W.2
Kim, S.G.3
-
25
-
-
34547675747
-
Correlation between expression of leptin and clinicopathological features and prognosis in patients with gastric cancer
-
X. Zhao, K. Huang, and Z. Zhu et al. Correlation between expression of leptin and clinicopathological features and prognosis in patients with gastric cancer J. Gastroenterol. Hepatol. 22 2007 1317 1321
-
(2007)
J. Gastroenterol. Hepatol.
, vol.22
, pp. 1317-1321
-
-
Zhao, X.1
Huang, K.2
Zhu, Z.3
-
26
-
-
0024306997
-
Prospective study of relative weight, height, and risk of breast cancer
-
S.J. London, G.A. Colditz, and M.J. Stampfer et al. Prospective study of relative weight, height, and risk of breast cancer JAMA 262 1989 2853 2858
-
(1989)
JAMA
, vol.262
, pp. 2853-2858
-
-
London, S.J.1
Colditz, G.A.2
Stampfer, M.J.3
-
27
-
-
31644449734
-
Possible involvement of leptin and leptin receptor in developing gastric adenocarcinoma
-
L. Zhao, Z.X. Shen, and H.S. Luo et al. Possible involvement of leptin and leptin receptor in developing gastric adenocarcinoma World J. Gastroenterol. 11 2005 7666 7670
-
(2005)
World J. Gastroenterol.
, vol.11
, pp. 7666-7670
-
-
Zhao, L.1
Shen, Z.X.2
Luo, H.S.3
-
28
-
-
62849109985
-
Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells
-
J. Gao, J. Tian, and Y. Lv et al. Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells Cancer Sci. 100 2009 389 395
-
(2009)
Cancer Sci.
, vol.100
, pp. 389-395
-
-
Gao, J.1
Tian, J.2
Lv, Y.3
-
29
-
-
79960877961
-
Role of the long form leptin receptor and of the STAT3 signaling pathway in colorectal cancer progression
-
T. Uchiyama, H. Takahashi, and H. Endo et al. Role of the long form leptin receptor and of the STAT3 signaling pathway in colorectal cancer progression Int. J. Oncol. 39 2011 935 940
-
(2011)
Int. J. Oncol.
, vol.39
, pp. 935-940
-
-
Uchiyama, T.1
Takahashi, H.2
Endo, H.3
-
30
-
-
77955671392
-
Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase
-
N. Stefanou, V. Papanikolaou, and Y. Furukawa et al. Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase BMC Cancer 10 2010 442
-
(2010)
BMC Cancer
, vol.10
, pp. 442
-
-
Stefanou, N.1
Papanikolaou, V.2
Furukawa, Y.3
-
31
-
-
79953705077
-
Estrogen receptor alpha pathway is involved in leptin-induced ovarian cancer cell growth
-
J.H. Choi, K.T. Lee, and P.C. Leung Estrogen receptor alpha pathway is involved in leptin-induced ovarian cancer cell growth Carcinogenesis 32 2011 589 596
-
(2011)
Carcinogenesis
, vol.32
, pp. 589-596
-
-
Choi, J.H.1
Lee, K.T.2
Leung, P.C.3
-
32
-
-
33749328700
-
STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis
-
L.M. Judd, K. Bredin, and A. Kalantzis et al. STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis Gastroenterology 131 2006 1073 1085
-
(2006)
Gastroenterology
, vol.131
, pp. 1073-1085
-
-
Judd, L.M.1
Bredin, K.2
Kalantzis, A.3
-
33
-
-
18844376579
-
Leptin activates STAT and ERK2 pathways and induces gastric cancer cell proliferation
-
R. Pai, C. Lin, and T. Tran et al. Leptin activates STAT and ERK2 pathways and induces gastric cancer cell proliferation Biochem. Biophys. Res. Commun. 331 2005 984 992
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.331
, pp. 984-992
-
-
Pai, R.1
Lin, C.2
Tran, T.3
-
34
-
-
33750607736
-
Leptin-mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in rats
-
M. Kitade, H. Yoshiji, and H. Kojima et al. Leptin-mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in rats Hepatology 44 2006 983 991
-
(2006)
Hepatology
, vol.44
, pp. 983-991
-
-
Kitade, M.1
Yoshiji, H.2
Kojima, H.3
-
35
-
-
0035973147
-
Potential role of leptin in angiogenesis: Leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro
-
H.Y. Park, H.M. Kwon, and H.J. Lim et al. Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro Exp. Mol. Med. 33 2001 95 102
-
(2001)
Exp. Mol. Med.
, vol.33
, pp. 95-102
-
-
Park, H.Y.1
Kwon, H.M.2
Lim, H.J.3
-
36
-
-
69249227496
-
Expression of angiogenic regulators, VEGF and leptin, is regulated by the EGF/PI3K/STAT3 pathway in colorectal cancer cells
-
S. Cascio, R. Ferla, and A. D'Andrea et al. Expression of angiogenic regulators, VEGF and leptin, is regulated by the EGF/PI3K/STAT3 pathway in colorectal cancer cells J. Cell. Physiol. 221 2009 189 194
-
(2009)
J. Cell. Physiol.
, vol.221
, pp. 189-194
-
-
Cascio, S.1
Ferla, R.2
D'Andrea, A.3
|