HIV virions as nanoscopic test tubes for probing oligomerization of the integrase enzyme

ACS Nano

Volumn 8, Issue 4, 2014, Pages 3531-3545

  Borrenberghs, Doortje ^a   Thys, Wannes ^b   Rocha, Susana ^a   Demeulemeester, Jonas ^b   Weydert, Caroline ^b   Dedecker, Peter ^a   Hofkens, Johan ^a,c   Debyser, Zeger ^b   Hendrix, Jelle ^a  

^a Katholieke Universiteit Leuven   (Belgium)

^b DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

F rster resonance energy transfer; HIV 1 integrase; nanoscopy; protein protein interactions; single molecule fluorescence microscopy; stoichiometry

Indexed keywords

DISEASES; ENERGY TRANSFER; ENZYMES; MOLECULES; OLIGOMERIZATION; OLIGOMERS; PROTEINS; STOICHIOMETRY; TUBES (COMPONENTS);

HIV-1 INTEGRASE; NANOSCOPY; PROTEIN-PROTEIN INTERACTIONS; RESONANCE ENERGY TRANSFER; SINGLE-MOLECULE FLUORESCENCE MICROSCOPY;

VIRUSES;

INTEGRASE; P31 INTEGRASE PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELL LINE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; NANOTECHNOLOGY; PROCEDURES; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; VIRION;

BIOCATALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELLS; HIV INTEGRASE; HIV-1; HUMANS; MODELS, MOLECULAR; NANOTECHNOLOGY; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; VIRION;

EID: 84899434824     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn406615v     Document Type: Article

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