CD8+ regulatory T cells, and not CD4+ T cells, dominate suppressive phenotype and function after in vitro live Mycobacterium bovis-BCG activation of human cells

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Boer, Mardi C ^a   Van Meijgaarden, Krista E ^a   Joosten, Simone A ^a   Ottenhoff, Tom H M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; INTERLEUKIN 2 RECEPTOR ALPHA; LIVE VACCINE; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; TRANSCRIPTION FACTOR FOXP3; MEMBRANE ANTIGEN;

ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DENSITY; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENRICHMENT CULTURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREGULATION; IN VITRO STUDY; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; MYCOBACTERIUM BOVIS BCG; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; IMMUNOLOGY; IMMUNOMODULATION; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; METABOLISM; MYCOBACTERIUM BOVIS; T LYMPHOCYTE SUBPOPULATION;

ANTIGENS, SURFACE; BCG VACCINE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; HUMANS; IMMUNOMODULATION; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; MYCOBACTERIUM BOVIS; PHENOTYPE; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 84899421603     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094192     Document Type: Article

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