Methylmalonic acid quantification in low serum volumes by UPLC-MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 19, 2011, Pages 1502-1506

  Pedersen, Theresa L ^a   Keyes, William R ^a   Shahab Ferdows, Setareh ^a   Allen, Lindsay H ^a   Newman, John W ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

LC MS MS; Methylmalonic acid; Nutrition; UPLC; Vitamin B12 status

Indexed keywords

AMMONIUM FORMATE; CALIBRATION SOLUTIONS; CHROMATOGRAPHIC RESOLUTIONS; CLINICAL BIOMARKERS; DIRECT ASSESSMENT; FREEZE/THAW CYCLES; FROZEN SAMPLE; HUMAN SERUM; INTER-ASSAY VARIABILITY; INTERNAL STANDARDS; ISOCRATIC; LC-MS/MS; METABOLIC INTERMEDIATES; METHYLMALONIC ACID; PEAK SHAPES; SAMPLE CONCENTRATION; SAMPLE PROCESSING; SCALING DOWN; SUCCINIC ACIDS; UPLC; UPLC-MS/MS; VITAMIN B; VITAMIN B12; VITAMIN B12 STATUS; WATER BASED;

AMMONIUM COMPOUNDS; BODY FLUIDS; DEUTERIUM; NUTRITION; OPTIMIZATION; VITAMINS;

FATTY ACIDS;

AMMONIUM FORMATE; CYANOCOBALAMIN; METHYLMALONIC ACID; SUCCINIC ACID;

ARTICLE; CALIBRATION; CATALYSIS; FREEZE THAWING; HUMAN; INFANT; MASS SPECTROMETRY; NEWBORN; NUTRITIONAL STATUS; PH; PRIORITY JOURNAL; SERUM; SIGNAL NOISE RATIO; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOHEXANES; DRUG STABILITY; FEMALE; HUMANS; LAURIC ACIDS; LINEAR MODELS; LONGITUDINAL STUDIES; METHYLMALONIC ACID; REPRODUCIBILITY OF RESULTS; RURAL POPULATION; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

EID: 79955914872     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.03.039     Document Type: Article

References (19)

1. Kennedy D.G., Kennedy S., Blanchflower W.J., Scott J.M., Weir D.G., Molloy A.M., Young P.B. Br. J. Nutr. 1994, 71:67.
2. Monsen A.L., Refsum H., Markestad T., Ueland P.M. Clin. Chem. 2003, 49:2067.
3. Luo X., Zhang L., Wei H., Liu W., Wang M., Ning Q. J. Huazhong Univ. Sci. Technol. Med. Sci. 2004, 24:166.
4. Matteini A.M., Walston J.D., Fallin M.D., Bandeen-Roche K., Kao W.H., Semba R.D., Allen R.H., Guralnik J., Fried L.P., Stabler S.P. J. Nutr. Health Aging 2008, 12:303.
5. Selhub J., Jacques P.F., Dallal G., Choumenkovitch S., Rogers G. Food Nutr. Bull. 2008, 29:S67.
6. Hempen C., Wanschers H., van der Sluijs Veer G. Anal. Bioanal. Chem. 2008, 391:263.
7. Kushnir M.M., Komaromy-Hiller G., Shushan B., Urry F.M., Roberts W.L. Clin. Chem. 2001, 47:1993.
8. Yazdanpanah M., Chan P.C., Evrovski J., Romaschin A., Cole D.E. Clin. Biochem. 2003, 36:617.
9. Lakso H.A., Appelblad P., Schneede J. Clin. Chem. 2008, 54:2028.
10. Turgeon C.T., Magera M.J., Cuthbert C.D., Loken P.R., Gavrilov D.K., Tortorelli S., Raymond K.M., Oglesbee D., Rinaldo P., Matern D. Clin. Chem. 2010, 56:1686.
11. Bjorke-Monsen A.L., Ueland P.M. J. Inherit. Metab. Dis. 2011, 34:111.
12. Shearer G.C., Harris W.S., Pedersen T.L., Newman J.W. J. Lipid Res. 2009.
13. Magera M.J., Helgeson J.K., Matern D., Rinaldo P. Clin. Chem. 2000, 46:1804.
14. Schmedes A., Brandslund I. Clin. Chem. 2006, 52:754.
15. Chen J., Bennett M.J. Methods Mol. Biol. 2010, 603:365.
16. Reineks E.Z., Hughes A., Wang S. Clin. Chem. Lab. Med. 2010, 48:1351.
17. Kushnir M.M., Rockwood A.L., Bergquist J. Mass Spectrom. Rev. 2010, 29:480.
18. Pfeiffer C.M., Caudill S.P., Gunter E.W., Osterloh J., Sampson E.J. Am. J. Clin. Nutr. 2005, 82:442.
19. Erdogan E., Nelson G.J., Rockwood A.L., Frank E.L. Clin. Chim. Acta 2010, 411:1827.