Block of the mevalonate pathway triggers oxidative and inflammatory molecular mechanisms modulated by exogenous isoprenoid compounds

International Journal of Molecular Sciences

Volumn 15, Issue 4, 2014, Pages 6843-6856

  Tricarico, Paola Maura ^a   Kleiner, Giulio ^b   Valencic, Erica ^b   Campisciano, Giuseppina ^a   Girardelli, Martina ^b   Crovella, Sergio ^a,b   Knowles, Alessandra ^b   Marcuzzi, Annalisa ^b  

^a UNIVERSITY OF TRIESTE   (Italy)

^b INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

Author keywords

Inflammation; Isoprenoids; Lycopene; Mevalonate; Phytol

Indexed keywords

FARNESOL; GERANIOL; GERANYLGERANIOL; ISOPRENOID; LYCOPENE; MENTHOL; NITRIC OXIDE; PHYTOL; CAROTENOID; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; CYTOKINE; DITERPENE; MEVALONIC ACID; TERPENE;

ANIMAL CELL; ARTICLE; ATAXIA; BODY DYSMORPHIC DISORDER; CEREBELLUM ATROPHY; CYTOKINE RELEASE; FEVER; FLOW CYTOMETRY; IMMUNOASSAY; INFLAMMATION; METABOLISM; MEVALONATE KINASE DEFICIENCY; MEVALONATE PATHWAY; NONHUMAN; OXIDATIVE STRESS; PSYCHOMOTOR RETARDATION; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; APOPTOSIS; CELL LINE; DRUG EFFECTS; HUMAN; MITOCHONDRION; MOUSE; PATHOLOGY; TOXICITY;

ANIMALS; APOPTOSIS; CAROTENOIDS; CARRIER PROTEINS; CELL LINE; CYTOKINES; DITERPENES; HUMANS; MEVALONATE KINASE DEFICIENCY; MEVALONIC ACID; MICE; MITOCHONDRIA; NITRIC OXIDE; PHYTOL; TERPENES;

EID: 84899144232     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15046843     Document Type: Article

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