Validation of the ligase detection reaction fluorescent microsphere assay for the detection of Plasmodium falciparum resistance mediating polymorphisms in Uganda

Malaria Journal

Volumn 13, Issue 1, 2014, Pages

  Nankoberanyi, Sheila ^a,c   Mbogo, George W ^a,c   Leclair, Norbert P ^b   Conrad, Melissa D ^b   Tumwebaze, Patrick ^a,c   Tukwasibwe, Stephen ^a,c   Kamya, Moses R ^a,c   Tappero, Jordan ^d   Nsobya, Samuel L ^a,c   Rosenthal, Philip J ^b  

^a INFECTIOUS DISEASES RESEARCH COLLABORATION   (Uganda)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MAKERERE UNIVERSITY   (Uganda)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

Drug resistance; Fluorescent microsphere assay; Malaria; Plasmodium falciparum; Polymorphisms

Indexed keywords

CHLOROQUINE; DNA; LIGASE; MICROBIAL ENZYME;

AMPLICON; ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; BLOOD SMEAR; CHILD; CONTROLLED STUDY; DNA EXTRACTION; DRIED BLOOD SPOT TESTING; ENZYME ASSAY; HUMAN; INFANT; LIGASE DETECTION REACTION FLUORESCENT MICROSPHERE ASSAY; MICROORGANISM DETECTION; NONHUMAN; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; UGANDA; VALIDATION STUDY;

CHILD, PRESCHOOL; DNA, PROTOZOAN; DRUG RESISTANCE; FEMALE; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INFANT; LIGASES; LONGITUDINAL STUDIES; MALARIA, FALCIPARUM; MALE; MICROSPHERES; MOLECULAR DIAGNOSTIC TECHNIQUES; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; UGANDA;

EID: 84899120164     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-13-95     Document Type: Article

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