Optimization of a ligase detection reaction-fluorescent microsphere assay for characterization of resistance-mediating polymorphisms in African samples of Plasmodium falciparum

Journal of Clinical Microbiology

Volumn 51, Issue 8, 2013, Pages 2564-2570

  LeClair, Norbert P ^a   Conrad, Melissa D ^a   Baliraine, Frederick N ^a,c   Nsanzabana, Christian ^a,d   Nsobya, Samuel L ^b   Rosenthal, Philip J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MAKERERE UNIVERSITY   (Uganda)

^c LETOURNEAU UNIVERSITY   (United States)

^d WorldWide Antimalarial Resistance Network   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; LIGASE; MICROSPHERE;

ARTICLE; CONTROLLED STUDY; DNA EXTRACTION; ENZYME ANALYSIS; GENE; GENE FREQUENCY; GENETIC POLYMORPHISM; HAPLOTYPE; HIGH THROUGHPUT SCREENING; HYBRIDIZATION; IMMUNOASSAY; MULTIPLEX LIGASE DETECTION REACTION FLUORESCENT MICROSPHERE ASSAY; NONHUMAN; PARASITE IDENTIFICATION; PFCRT GENE; PFDHFR GENE; PFDHPS GENE; PFMDR1 GENE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ANTIMALARIALS; BLOOD; DRUG RESISTANCE; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIGASES; MALARIA, FALCIPARUM; MICROSPHERES; MOLECULAR DIAGNOSTIC TECHNIQUES; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; POLYMORPHISM, GENETIC; UGANDA;

EID: 84880640225     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.00904-13     Document Type: Article

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