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Volumn 121, Issue 3, 2012, Pages 184-195

Malaria in Uganda: Challenges to control on the long road to elimination. I. Epidemiology and current control efforts

Author keywords

Artemisinin based combination therapy; Indoor residual spraying; Insecticide treated nets; Intermittent preventive therapy; Malaria; Uganda

Indexed keywords

AMODIAQUINE PLUS ARTESUNATE; ANTIMALARIAL AGENT; ARTEMETHER PLUS BENFLUMETOL; ARTEMISININ; ARTESUNATE; CHLOROQUINE; COTRIMOXAZOLE; INSECTICIDE; PYRIMETHAMINE PLUS SULFADOXINE; QUININE;

EID: 84857656541     PISSN: 0001706X     EISSN: 18736254     Source Type: Journal    
DOI: 10.1016/j.actatropica.2011.03.004     Document Type: Article
Times cited : (160)

References (56)
  • 1
    • 13744254259 scopus 로고    scopus 로고
    • Rectal artemether versus intravenous quinine for the treatment of cerebral malaria in children in Uganda: randomised clinical trial
    • Aceng J.R., Byarugaba J.S., Tumwine J.K. Rectal artemether versus intravenous quinine for the treatment of cerebral malaria in children in Uganda: randomised clinical trial. BMJ 2005, 330:334.
    • (2005) BMJ , vol.330 , pp. 334
    • Aceng, J.R.1    Byarugaba, J.S.2    Tumwine, J.K.3
  • 2
    • 38449092730 scopus 로고    scopus 로고
    • Rectal versus intravenous quinine for the treatment of childhood cerebral malaria in Kampala, Uganda: a randomized, double-blind clinical trial
    • Achan J., Byarugaba J., Barennes H., Tumwine J.K. Rectal versus intravenous quinine for the treatment of childhood cerebral malaria in Kampala, Uganda: a randomized, double-blind clinical trial. Clin. Infect. Dis. 2007, 45:1446-1452.
    • (2007) Clin. Infect. Dis. , vol.45 , pp. 1446-1452
    • Achan, J.1    Byarugaba, J.2    Barennes, H.3    Tumwine, J.K.4
  • 7
    • 75849164601 scopus 로고    scopus 로고
    • Plasma levels of DDT/DDE and liver function in malaria control personnel 6 months after indoor residual spraying with DDT in northern Uganda, 2008
    • Bimenya G.S., Harabulema M., Okot J.P., Francis O., Lugemwa M., Okwi A.L. Plasma levels of DDT/DDE and liver function in malaria control personnel 6 months after indoor residual spraying with DDT in northern Uganda, 2008. S. Afr. Med. J. 2010, 100:118-121.
    • (2010) S. Afr. Med. J. , vol.100 , pp. 118-121
    • Bimenya, G.S.1    Harabulema, M.2    Okot, J.P.3    Francis, O.4    Lugemwa, M.5    Okwi, A.L.6
  • 8
    • 0034972445 scopus 로고    scopus 로고
    • The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden
    • Breman J.G. The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. Am. J. Trop. Med. Hyg. 2001, 64(suppl):1-11.
    • (2001) Am. J. Trop. Med. Hyg. , vol.64 , Issue.SUPPL. , pp. 1-11
    • Breman, J.G.1
  • 12
    • 23944443703 scopus 로고    scopus 로고
    • Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial
    • Dondorp A., Nosten F., Stepniewska K., Day N., White N. Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet 2005, 366:717-725.
    • (2005) Lancet , vol.366 , pp. 717-725
    • Dondorp, A.1    Nosten, F.2    Stepniewska, K.3    Day, N.4    White, N.5
  • 16
    • 0035341936 scopus 로고    scopus 로고
    • Polymorphisms in the Plasmodium falciparum pfcrt and pfmdr-1 genes and clinical response to chloroquine in Kampala, Uganda
    • Dorsey G., Kamya M.R., Singh A., Rosenthal P.J. Polymorphisms in the Plasmodium falciparum pfcrt and pfmdr-1 genes and clinical response to chloroquine in Kampala, Uganda. J. Infect. Dis. 2001, 183:1417-1420.
    • (2001) J. Infect. Dis. , vol.183 , pp. 1417-1420
    • Dorsey, G.1    Kamya, M.R.2    Singh, A.3    Rosenthal, P.J.4
  • 17
    • 0037153723 scopus 로고    scopus 로고
    • Sulfadoxine/pyrimethamine alone or with amodiaquine or artesunate for treatment of uncomplicated malaria: a longitudinal randomised trial
    • Dorsey G., Njama D., Kamya M.R., Cattamanchi A., Kyabayinze D., Staedke S.G., Gasasira A., Rosenthal P.J. Sulfadoxine/pyrimethamine alone or with amodiaquine or artesunate for treatment of uncomplicated malaria: a longitudinal randomised trial. Lancet 2002, 360:2031-2038.
    • (2002) Lancet , vol.360 , pp. 2031-2038
    • Dorsey, G.1    Njama, D.2    Kamya, M.R.3    Cattamanchi, A.4    Kyabayinze, D.5    Staedke, S.G.6    Gasasira, A.7    Rosenthal, P.J.8
  • 19
    • 78149362174 scopus 로고    scopus 로고
    • Call to action: priorities for malaria elimination
    • Feachem R.G., Phillips A.A., Targett G.A., Snow R.W. Call to action: priorities for malaria elimination. Lancet 2010, 376:1517-1521.
    • (2010) Lancet , vol.376 , pp. 1517-1521
    • Feachem, R.G.1    Phillips, A.A.2    Targett, G.A.3    Snow, R.W.4
  • 20
    • 33645355649 scopus 로고    scopus 로고
    • Geographic differences in antimalarial drug efficacy in Uganda are explained by differences in endemicity and not by known molecular markers of drug resistance
    • Francis D., Nsobya S.L., Talisuna A., Yeka A., Kamya M.R., Machekano R., Dokomajilar C., Rosenthal P.J., Dorsey G. Geographic differences in antimalarial drug efficacy in Uganda are explained by differences in endemicity and not by known molecular markers of drug resistance. J. Infect. Dis. 2006, 193:978-986.
    • (2006) J. Infect. Dis. , vol.193 , pp. 978-986
    • Francis, D.1    Nsobya, S.L.2    Talisuna, A.3    Yeka, A.4    Kamya, M.R.5    Machekano, R.6    Dokomajilar, C.7    Rosenthal, P.J.8    Dorsey, G.9
  • 23
  • 24
    • 0035726310 scopus 로고    scopus 로고
    • The comparative efficacy of chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in Kampala, Uganda
    • Kamya M.R., Dorsey G., Gasasira A., Ndeezi G., Babirye J.N., Staedke S.G., Rosenthal P.J. The comparative efficacy of chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in Kampala, Uganda. Trans. R. Soc. Trop. Med. Hyg. 2001, 95:50-55.
    • (2001) Trans. R. Soc. Trop. Med. Hyg. , vol.95 , pp. 50-55
    • Kamya, M.R.1    Dorsey, G.2    Gasasira, A.3    Ndeezi, G.4    Babirye, J.N.5    Staedke, S.G.6    Rosenthal, P.J.7
  • 28
    • 77955606277 scopus 로고    scopus 로고
    • Pyrethroid resistance in an Anopheles funestus population from Uganda
    • Morgan J.C., Irving H., Okedi L.M., Steven A., Wondji C.S. Pyrethroid resistance in an Anopheles funestus population from Uganda. PLoS One 2010, 5:e11872.
    • (2010) PLoS One , vol.5
    • Morgan, J.C.1    Irving, H.2    Okedi, L.M.3    Steven, A.4    Wondji, C.S.5
  • 29
    • 78149462780 scopus 로고    scopus 로고
    • Efficacy, safety, and tolerability of three regimens for prevention of malaria: a randomized, placebo-controlled trial in Ugandan school children
    • Nankabirwa J., Cundill B., Clarke S., Kabatereine N., Rosenthal P.J., Dorsey G., Brooker S., Staedke S.G. Efficacy, safety, and tolerability of three regimens for prevention of malaria: a randomized, placebo-controlled trial in Ugandan school children. PLoS One 2010, 5:e13438.
    • (2010) PLoS One , vol.5
    • Nankabirwa, J.1    Cundill, B.2    Clarke, S.3    Kabatereine, N.4    Rosenthal, P.J.5    Dorsey, G.6    Brooker, S.7    Staedke, S.G.8
  • 30
    • 3142583289 scopus 로고    scopus 로고
    • Trends in malaria-attributable morbidity and mortality among young children admitted to Ugandan hospitals, for the period 1990-2001
    • Ndyomugyenyi R., Magnussen P. Trends in malaria-attributable morbidity and mortality among young children admitted to Ugandan hospitals, for the period 1990-2001. Ann. Trop. Med. Parasitol. 2004, 98:315-327.
    • (2004) Ann. Trop. Med. Parasitol. , vol.98 , pp. 315-327
    • Ndyomugyenyi, R.1    Magnussen, P.2
  • 31
    • 0036271177 scopus 로고    scopus 로고
    • Appropriate treatment of malaria? Use of antimalarial drugs for children's fevers in district medical units, drug shops and homes in eastern Uganda
    • Nshakira N., Kristensen M., Ssali F., Whyte S.R. Appropriate treatment of malaria? Use of antimalarial drugs for children's fevers in district medical units, drug shops and homes in eastern Uganda. Trop. Med. Int. Health 2002, 7:309-316.
    • (2002) Trop. Med. Int. Health , vol.7 , pp. 309-316
    • Nshakira, N.1    Kristensen, M.2    Ssali, F.3    Whyte, S.R.4
  • 36
    • 84857650396 scopus 로고    scopus 로고
    • President's Malaria Initiative, 2010. President's Malaria Initiative Uganda Malaria Operational Plan for FY
    • President's Malaria Initiative, 2010. President's Malaria Initiative Uganda Malaria Operational Plan for FY 2010.
    • (2010)
  • 37
    • 70349808481 scopus 로고    scopus 로고
    • Insecticide resistance and its association with target-site mutations in natural populations of Anopheles gambiae from eastern Uganda
    • Ramphul U., Boase T., Bass C., Okedi L.M., Donnelly M.J., Muller P. Insecticide resistance and its association with target-site mutations in natural populations of Anopheles gambiae from eastern Uganda. Trans. R. Soc. Trop. Med. Hyg. 2009, 103:1121-1126.
    • (2009) Trans. R. Soc. Trop. Med. Hyg. , vol.103 , pp. 1121-1126
    • Ramphul, U.1    Boase, T.2    Bass, C.3    Okedi, L.M.4    Donnelly, M.J.5    Muller, P.6
  • 38
    • 70349238759 scopus 로고    scopus 로고
    • Caution is required when using health facility-based data to evaluate the health impact of malaria control efforts in Africa
    • Rowe A.K., Kachur S.P., Yoon S.S., Lynch M., Slutsker L., Steketee R.W. Caution is required when using health facility-based data to evaluate the health impact of malaria control efforts in Africa. Malar. J. 2009, 8:209.
    • (2009) Malar. J. , vol.8 , pp. 209
    • Rowe, A.K.1    Kachur, S.P.2    Yoon, S.S.3    Lynch, M.4    Slutsker, L.5    Steketee, R.W.6
  • 39
    • 45549097733 scopus 로고    scopus 로고
    • Reduced susceptibility to pyrethroid insecticide treated nets by the malaria vector Anopheles gambiae s.l. in western Uganda
    • Rubaihayo J., Tukesiga E., Abaasa A. Reduced susceptibility to pyrethroid insecticide treated nets by the malaria vector Anopheles gambiae s.l. in western Uganda. Malar. J. 2008, 7:92.
    • (2008) Malar. J. , vol.7 , pp. 92
    • Rubaihayo, J.1    Tukesiga, E.2    Abaasa, A.3
  • 40
    • 0032879805 scopus 로고    scopus 로고
    • Estimating mortality, morbidity and disability due to malaria among Africa's non-pregnant population
    • Snow R.W., Craig M., Deichmann U., Marsh K. Estimating mortality, morbidity and disability due to malaria among Africa's non-pregnant population. Bull. World Health Organ. 1999, 77:624-640.
    • (1999) Bull. World Health Organ. , vol.77 , pp. 624-640
    • Snow, R.W.1    Craig, M.2    Deichmann, U.3    Marsh, K.4
  • 41
    • 15044338866 scopus 로고    scopus 로고
    • The global distribution of clinical episodes of Plasmodium falciparum malaria
    • Snow R.W., Guerra C.A., Noor A.M., Myint H.Y., Hay S.I. The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 2005, 434:214-217.
    • (2005) Nature , vol.434 , pp. 214-217
    • Snow, R.W.1    Guerra, C.A.2    Noor, A.M.3    Myint, H.Y.4    Hay, S.I.5
  • 42
    • 0035806761 scopus 로고    scopus 로고
    • Amodiaquine, sulfadoxine/pyrimethamine, and combination therapy for treatment of uncomplicated falciparum malaria in Kampala, Uganda: a randomised trial
    • Staedke S.G., Kamya M.R., Dorsey G., Gasasira A., Ndeezi G., Charlebois E.D., Rosenthal P.J. Amodiaquine, sulfadoxine/pyrimethamine, and combination therapy for treatment of uncomplicated falciparum malaria in Kampala, Uganda: a randomised trial. Lancet 2001, 358:368-374.
    • (2001) Lancet , vol.358 , pp. 368-374
    • Staedke, S.G.1    Kamya, M.R.2    Dorsey, G.3    Gasasira, A.4    Ndeezi, G.5    Charlebois, E.D.6    Rosenthal, P.J.7
  • 43
    • 9644269050 scopus 로고    scopus 로고
    • Combination treatments for uncomplicated falciparum malaria in Kampala, Uganda: randomised clinical trial
    • Staedke S.G., Mpimbaza A., Kamya M.R., Nzarubara B.K., Dorsey G., Rosenthal P.J. Combination treatments for uncomplicated falciparum malaria in Kampala, Uganda: randomised clinical trial. Lancet 2004, 364:1950-1957.
    • (2004) Lancet , vol.364 , pp. 1950-1957
    • Staedke, S.G.1    Mpimbaza, A.2    Kamya, M.R.3    Nzarubara, B.K.4    Dorsey, G.5    Rosenthal, P.J.6
  • 44
  • 45
    • 84857644591 scopus 로고    scopus 로고
    • Uganda Bureau of Statistics, 2007. Uganda Demographic and Health Survey
    • Uganda Bureau of Statistics, 2007. Uganda Demographic and Health Survey 2006.
    • (2006)
  • 46
    • 84857650394 scopus 로고    scopus 로고
    • Uganda Bureau of Statistics, 2010. Uganda Malaria Indicator Survey
    • Uganda Bureau of Statistics, 2010. Uganda Malaria Indicator Survey 2009.
    • (2009)
  • 47
    • 84857644588 scopus 로고    scopus 로고
    • Uganda Ministry of Health, 2005. Uganda Malaria Control Strategic Plan 2005/6-2009/10.
    • Uganda Ministry of Health, 2005. Uganda Malaria Control Strategic Plan 2005/6-2009/10.
  • 48
    • 84857647808 scopus 로고    scopus 로고
    • Uganda Ministry of Health, 2008. Service Provision Assessment Survey
    • Uganda Ministry of Health, 2008. Service Provision Assessment Survey 2007.
    • (2007)
  • 49
  • 50
    • 33646359676 scopus 로고    scopus 로고
    • Detection of the East and West African kdr mutation in Anopheles gambiae and Anopheles arabiensis from Uganda using a new assay based on FRET/Melt curve analysis
    • Verhaeghen K., Van Bortel W., Roelants P., Backeljau T., Coosemans M. Detection of the East and West African kdr mutation in Anopheles gambiae and Anopheles arabiensis from Uganda using a new assay based on FRET/Melt curve analysis. Malar. J. 2006, 5:16.
    • (2006) Malar. J. , vol.5 , pp. 16
    • Verhaeghen, K.1    Van Bortel, W.2    Roelants, P.3    Backeljau, T.4    Coosemans, M.5
  • 51
    • 0033167028 scopus 로고    scopus 로고
    • Elevated oxidase and esterase levels associated with permethrin tolerance in Anopheles gambiae from Kenyan villages using permethrin-impregnated nets
    • Vulule J.M., Beach R.F., Atieli F.K., McAllister J.C., Brogdon W.G., Roberts J.M., Mwangi R.W., Hawley W.A. Elevated oxidase and esterase levels associated with permethrin tolerance in Anopheles gambiae from Kenyan villages using permethrin-impregnated nets. Med. Vet. Entomol. 1999, 13:239-244.
    • (1999) Med. Vet. Entomol. , vol.13 , pp. 239-244
    • Vulule, J.M.1    Beach, R.F.2    Atieli, F.K.3    McAllister, J.C.4    Brogdon, W.G.5    Roberts, J.M.6    Mwangi, R.W.7    Hawley, W.A.8
  • 52
    • 84857650392 scopus 로고    scopus 로고
    • World Health Organization, World Malaria Report. World Health Organization, Geneva.
    • World Health Organization, 2008. World Malaria Report. World Health Organization, Geneva.
    • (2008)
  • 53
    • 84857650393 scopus 로고    scopus 로고
    • World Health Organization, Guidelines for the Treatment of Malaria. World Health Organization, Geneva.
    • World Health Organization, 2010. Guidelines for the Treatment of Malaria. World Health Organization, Geneva.
    • (2010)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.