Granulocyte/macrophage colony-stimulating factor influences angiogenesis by regulating the coordinated expression of VEGF and the Ang/Tie system

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Zhao, Jingling ^a   Chen, Lei ^a   Shu, Bin ^a   Tang, Jinming ^a   Zhang, Lijun ^a   Xie, Julin ^a   Qi, Shaohai ^a   Xu, Yingbin ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BLOOD VESSEL FUNCTION; BURN; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; NONHUMAN; PERICYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; WOUND HEALING;

ANIMALS; BURNS; CELL PROLIFERATION; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOVASCULARIZATION, PHYSIOLOGIC; PERICYTES; PHOSPHORYLATION; RATS; RECEPTORS, TIE; RIBONUCLEASE, PANCREATIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 84899108656     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092691     Document Type: Article

References (51)

1. Martin P (1997) Wound healing-aiming for perfect skin regeneration. Science 276: 75-81.
2. Augustin HG, Koh GY, Thurston G, Alitalo K (2009) Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat Rev Mol Cell Biol 10: 165-177.
3. Thurston G, Suri C, Smith K (1999) Leakage-resistant blood vessels in mice transgenically over expressing angiopoitin-1. Science. pp. 2511-2514.
4. Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ, et al. (2000) Vascular specific growth factors and blood vessel formation. Nature 407: 242-248.
5. Mann A, Breuhahn K, Schirmacher P (2001) Keratinocyte-derived granulocyte-macrophage colony stimulating factor accelerates wound healing.Stimulation of keratinocyte proliferation,granulation tissue formation and vascularization. J Invest Dermatol 117: 1382-1390. (Pubitemid 34032763)
6. Fang Y, Gong SJ, Xu YH (2007) Impaired cutaneous wound healing in granulocyte/macrophage colony-stimulation factor knockout mice. Br J Dermatol 157: 458-465. (Pubitemid 47256111)
7. Imokawa G, Yada Y, Kimura M, Morisaki N (1996) Granulocyte/macrophage colony-stimulating factor is an intrinsic keratinocyte-derived growth factor for human melanocytes in UVA-induced melanosis. Biochem J 313 (Pt2): 625-631. (Pubitemid 26030157)
8. Bussolino F, Wang JM, Defilippi P, Turrini F, Sanavio F, et al. (1989) Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate. Nature 337: 471-473. (Pubitemid 19047464)
9. Kaplan G, Walsh G, Guido LS, Meyn P, Burkhardt RA, et al. (1992) Novel responses of human skin to intradermal recombinant granulocyte/macrophage- colony-stimulating factor: Langerhans cell recruitment, keratinocyte growth, and enhanced wound healing. J Exp Med 175: 1717-1728.
10. Canturk NZ, Vural B, Esen N, Canturk Z, Oktay G, et al. (1999) Effects of granulocyte-macrophage colony-stimulating factor on incisional wound healing in an experimental diabetic rat model. Endocr Res 25: 105-116. (Pubitemid 29109647)
11. Mery L, Girot R, Aractingi S (2004) Topical effectiveness of molgramostim (GM-CSF) in sickle cell leg ulcers. Dermatology 208: 135-137. (Pubitemid 38446012)
12. Mann A, Breuhahn K, Schirmacher P, Blessing M (2001) Keratinocyte-derived granulocyte-macrophage colony stimulating factor accelerates wound healing: Stimulation of keratinocyte proliferation, granulation tissue formation, and vascularization. J Invest Dermatol 117: 1382-1390. (Pubitemid 34032763)
13. Ure I, Partsch B, Wolff K, Petzelbauer P (1998) Granulocyte/macrophage colony-stimulating factor increases wound-fluid interleukin 8 in normal subjects but does not accelerate wound healing. Br J Dermatol 138: 277-282. (Pubitemid 28114131)
14. Voskaridou E, Kyrtsonis MC, Loutradi-Anagnostou A (1999) Healing of chronic leg ulcers in the hemoglobinopathies with perilesional injections of granulocyte-macrophage colony-stimulating factor. Blood 93: 3568-3569. (Pubitemid 29220927)
15. Yan H, Chen J, Peng X (2012) Recombinant human granulocyte-macrophage colony-stimulating factor hydrogel promotes healing of deep partial thickness burn wounds. Burns 38: 877-881.
16. Cianfarani F, Tommasi R, Failla CM (2006) Granulocyte /macrophage colony-stimulating factor treatment of human chronic ulcers promotes angiogenesis associated with de novo vascular endothelial growth factor transcription in the ulcer bed. Br J Dermatol 154: 34-41. (Pubitemid 43381317)
17. Davidson JM (1998) Animal models for wound repair. Arch Dermatol Res 290 Suppl: S1-S11.
18. Eberhard A, Kahlert S, Goede V, Hemmerlein B, Plate KH, et al. (2000) Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies. Cancer Res 60: 1388-1393. (Pubitemid 30152012)
19. Weidner N (1998) Tumoural vascularity as a prognostic factor in cancer patients: the evidence continues to grow. J Pathol 184: 119-122.
20. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408. (Pubitemid 34164012)
21. Zhang SX, Sima J, Shao C, Fant J, Chen Y, et al. (2004) Plasminogen kringle 5 reduces vascular leakage in the retina in rat models of oxygen-induced retinopathy and diabetes. Diabetologia 47: 124-131. (Pubitemid 38141948)
22. Shresta S, Sharar KL, Prigozhin DM, Beatty PR, Harris E (2006) Murine model for dengue virus-induced lethal disease with increased vascular permeability. J Virol 80: 10208-10217. (Pubitemid 44522614)
23. Goede V, Schmidt T, Kimmina S, Kozian D, Augustin HG (1998) Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis. Lab Invest 78: 1385-1394. (Pubitemid 28546082)
24. Bhushan M, Young HS, Brenchley PE, Griffiths CE (2002) Recent advances in cutaneous angiogenesis. Br J Dermatol 147: 418-425. (Pubitemid 35015272)
25. Karagiannis E, Popel A (2006) Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model. J Theor Biol 238: 124-145. (Pubitemid 41737802)
26. Gerhardt H, Betsholtz C (2003) Endothelial- pericyte interactions in angiogenesis. pp. 15-23.
27. Wakui S, Furusato M, Ohshige H, Ushigome S (1993) Endothelial-pericyte interdigitations in rat subcutaneous disc implanted angiogenesis. Microvasc Res 46: 19-27.
28. Schriber JR, Negrin RS, Chao NJ, Long GD, Horning SJ, et al. (1993) The efficacy of granulocyte colony-stimulating factor following autologous bone marrow transplantation for non-Hodgkin's lymphoma with monoclonal antibody purged bone marrow. Leukemia 7: 1491-1495. (Pubitemid 23319120)
29. Gorin NC, Coiffier B, Hayat M, Fouillard L, Kuentz M, et al. (1992) Recombinant human granulocyte-macrophage colony-stimulating factor after high-dose chemotherapy and autologous bone marrow transplantation with unpurged and purged marrow in non-Hodgkin's lymphoma: a double-blind placebo-controlled trial. Blood 80: 1149-1157.
30. Visani G, Tosi P, Gamberi B, Cenacchi A, Mazzanti P, et al. (1990) Accelerated hemopoietic recovery after chemotherapy and autologous bone marrow transplantation in hematological malignancies using recombinant GM-CSF: preliminary results obtained in 14 cases. Haematologica 75: 551-554.
31. Bussolino F, Mantovani A (1991) Effect of granulocyte-macrophage colony-stimulating factor on endothelial cells. Blood 78: 2475-2476.
32. Mery L, Girot R, Aractingi S (2004) Topical effectiveness of molgramostim (GM-CSF) in sickle cell leg ulcers. Dermatology 208: 135-137. (Pubitemid 38446012)
33. Groves RW, Schmidt-Lucke JA (2000) Recombinant human GM-CSF in the treatment of poorly healing wounds. Adv Skin Wound Care 13: 107-112.
34. Benest AV, Salmon AH, Wang W, Glover CP, Uney J, et al. (2006) VEGF and angiopoietin-1 stimulate different angiogenic phenotypes that combine to enhance functional neovascularization in adult tissue. Microcirculation 13: 423-437. (Pubitemid 44322159)
35. Staton CA, Valluru M, Hoh L, Reed MW, Brown NJ (2010) Angiopoietin-1, angiopoietin-2 and Tie-2 receptor expression in human dermal wound repair and scarring. Br J Dermatol 163: 920-927.
36. Valenzuela DM, Griffiths JA, Rojas J, Aldrich TH, Jones PF, et al. (1999) Angiopoietins 3 and 4: diverging gene counterparts in mice and humans. Proc Natl Acad Sci U S A 96: 1904-1909. (Pubitemid 29117840)
37. Lee HJ, Cho CH, Hwang SJ, Choi HH, Kim KT, et al. (2004) Biological characterization of angiopoietin-3 and angiopoietin-4. FASEB J 18: 1200-1208. (Pubitemid 39006882)
38. Suri C, Jone PF, Patan S (1996) Requisite role of angiopoietin, a ligand for the TIE2 recepor, during embryonic angiogenesis. Cell. pp. 1171-1180. (Pubitemid 27010101)
39. Kim I, Kim HG, So JN, Kim JH, Kwak HJ, et al. (2000) Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway. Circ Res 86: 24-29. (Pubitemid 30044164)
40. Jeon BH, Khanday F, Deshpande S, Haile A, Ozaki M, et al. (2003) Tie-ing the antiinflammatory effect of angiopoietin-1 to inhibition of NF-kappaB. Circ Res 92: 586-588. (Pubitemid 36417689)
41. Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, et al. (1997) Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277: 55-60. (Pubitemid 27450643)
42. Reiss Y, Droste J, Heil M, Tribulova S, Schmidt MH, et al. (2007) Angiopoietin-2 impairs revascularization after limb ischemia. Circ Res 101: 88-96. (Pubitemid 47094627)
43. Benest AV, Kruse K, Savant S, Thomas M, Laib AM, et al. (2013) Angiopoietin-2 is critical for cytokine-induced vascular leakage. PLoS One 8: e70459.
44. Etoh T, Inoue H, Tanaka S, Barnard GF, Kitano S, et al. (2001) Angiopoietin-2 is related to tumor angiogenesis in gastric carcinoma: possible in vivo regulation via induction of proteases. Cancer Res 61: 2145-2153. (Pubitemid 32692040)
45. Holash J, Wiegand SJ, Yancopoulos GD (1999) New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF. Oncogene 18: 5356-5362. (Pubitemid 29462372)
46. Somerville RP, Oblander SA, Apte SS (2003) Matrix metalloproteinases: old dogs with new tricks. Genome Biol 4: 216.
47. Bhushan M, Young HS, Brenchley PE, Griffiths CE (2002) Recent advances in cutaneous angiogenesis. Br J Dermatol 147: 418-425. (Pubitemid 35015272)
48. Brindle NP, Saharinen P, Alitalo K (2006) Signaling and functions of angiopoietin-1 in vascular protection. Circ Res 98: 1014-1023.
49. Kutcher ME, Herman IM (2009) The pericyte: cellular regulator of microvascular blood flow. Microvasc Res 77: 235-246.
50. Hirschi KK, Rohovsky SA, Beck LH, Smith SR, D'Amore PA (1999) Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact. Circ Res 84: 298-305. (Pubitemid 29095570)
51. Gamble JR, Drew J, Trezise L, Underwood A, Parsons M, et al. (2000) Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions. Circ Res 87: 603-607.