메뉴 건너뛰기




Volumn 111, Issue 16, 2014, Pages

Integrative framework for identification of key cell identity genes uncovers determinants of ES cell identity and homeostasis

Author keywords

Computational biology; Pluripotency; RNA binding protein; ROS; Transcription

Indexed keywords

NUCLEOLIN; PROTEIN P53;

EID: 84899082334     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1318598111     Document Type: Article
Times cited : (24)

References (64)
  • 1
    • 77953626646 scopus 로고    scopus 로고
    • Genomic screening with RNAi: Results and challenges
    • Mohr S, Bakal C, Perrimon N (2010) Genomic screening with RNAi: Results and challenges. Annu Rev Biochem 79:37-64.
    • (2010) Annu Rev Biochem , vol.79 , pp. 37-64
    • Mohr, S.1    Bakal, C.2    Perrimon, N.3
  • 2
    • 45549089565 scopus 로고    scopus 로고
    • The art and design of genetic screens: RNA interference
    • DOI 10.1038/nrg2364, PII NRG2364
    • Boutros M, Ahringer J (2008) The art and design of genetic screens: RNA interference. Nat Rev Genet 9(7):554-566. (Pubitemid 351861541)
    • (2008) Nature Reviews Genetics , vol.9 , Issue.7 , pp. 554-566
    • Boutros, M.1    Ahringer, J.2
  • 3
    • 56349121125 scopus 로고    scopus 로고
    • An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer
    • Zender L, et al. (2008) An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer. Cell 135(5):852-864.
    • (2008) Cell , vol.135 , Issue.5 , pp. 852-864
    • Zender, L.1
  • 4
    • 66149091940 scopus 로고    scopus 로고
    • A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene
    • Luo J, et al. (2009) A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell 137(5):835-848.
    • (2009) Cell , vol.137 , Issue.5 , pp. 835-848
    • Luo, J.1
  • 5
    • 80055000824 scopus 로고    scopus 로고
    • RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
    • Zuber J, et al. (2011) RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature 478(7370):524-528.
    • (2011) Nature , vol.478 , Issue.7370 , pp. 524-528
    • Zuber, J.1
  • 7
    • 46149110511 scopus 로고    scopus 로고
    • An RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Identity
    • DOI 10.1016/j.cell.2008.05.031, PII S0092867408006922
    • Fazzio TG, Huff JT, Panning B (2008) An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity. Cell 134(1):162-174. (Pubitemid 351905738)
    • (2008) Cell , vol.134 , Issue.1 , pp. 162-174
    • Fazzio, T.G.1    Huff, J.T.2    Panning, B.3
  • 8
    • 64349096829 scopus 로고    scopus 로고
    • A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal
    • Hu G, et al. (2009) A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal. Genes Dev 23(7):837-848.
    • (2009) Genes Dev , vol.23 , Issue.7 , pp. 837-848
    • Hu, G.1
  • 9
    • 65349123354 scopus 로고    scopus 로고
    • A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity
    • Ding L, et al. (2009) A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell 4(5):403-415.
    • (2009) Cell Stem Cell , vol.4 , Issue.5 , pp. 403-415
    • Ding, L.1
  • 10
    • 78149465975 scopus 로고    scopus 로고
    • A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity
    • Chia NY, et al. (2010) A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature 468(7321):316-320.
    • (2010) Nature , vol.468 , Issue.7321 , pp. 316-320
    • Chia, N.Y.1
  • 11
    • 84876206165 scopus 로고    scopus 로고
    • A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration
    • Wuestefeld T, et al. (2013) A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration. Cell 153(2):389-401.
    • (2013) Cell , vol.153 , Issue.2 , pp. 389-401
    • Wuestefeld, T.1
  • 12
    • 51649095289 scopus 로고    scopus 로고
    • RNA interference screen for human genes associated with West Nile virus infection
    • Krishnan MN, et al. (2008) RNA interference screen for human genes associated with West Nile virus infection. Nature 455(7210):242-245.
    • (2008) Nature , vol.455 , Issue.7210 , pp. 242-245
    • Krishnan, M.N.1
  • 13
    • 84879539109 scopus 로고    scopus 로고
    • Genome-wide RNAi screen reveals a new role of a WNT/CTNNB1 signaling pathway as negative regulator of virus-induced innate immune responses
    • Baril M, et al. (2013) Genome-wide RNAi screen reveals a new role of a WNT/CTNNB1 signaling pathway as negative regulator of virus-induced innate immune responses. PLoS Pathog 9(6):e1003416.
    • (2013) PLoS Pathog , vol.9 , Issue.6
    • Baril, M.1
  • 14
    • 65349181366 scopus 로고    scopus 로고
    • Screening for novel regulators of embryonic stem cell identity
    • Subramanian V, Klattenhoff CA, Boyer LA (2009) Screening for novel regulators of embryonic stem cell identity. Cell Stem Cell 4(5):377-378.
    • (2009) Cell Stem Cell , vol.4 , Issue.5 , pp. 377-378
    • Subramanian, V.1    Klattenhoff, C.A.2    Boyer, L.A.3
  • 15
    • 79955572417 scopus 로고    scopus 로고
    • Harnessing the potential of induced pluripotent stem cells for regenerative medicine
    • Wu SM, Hochedlinger K (2011) Harnessing the potential of induced pluripotent stem cells for regenerative medicine. Nat Cell Biol 13(5):497-505.
    • (2011) Nat Cell Biol , vol.13 , Issue.5 , pp. 497-505
    • Wu, S.M.1    Hochedlinger, K.2
  • 16
    • 84856007232 scopus 로고    scopus 로고
    • The promise of induced pluripotent stem cells in research and therapy
    • Robinton DA, Daley GQ (2012) The promise of induced pluripotent stem cells in research and therapy. Nature 481(7381):295-305.
    • (2012) Nature , vol.481 , Issue.7381 , pp. 295-305
    • Robinton, D.A.1    Daley, G.Q.2
  • 17
    • 84875537133 scopus 로고    scopus 로고
    • Epigenetic reprogramming in cancer
    • Suvà ML, Riggi N, Bernstein BE (2013) Epigenetic reprogramming in cancer. Science 339(6127):1567-1570.
    • (2013) Science , vol.339 , Issue.6127 , pp. 1567-1570
    • Suvà, M.L.1    Riggi, N.2    Bernstein, B.E.3
  • 19
    • 79952660821 scopus 로고    scopus 로고
    • Control of the embryonic stem cell state
    • Young RA (2011) Control of the embryonic stem cell state. Cell 144(6):940-954.
    • (2011) Cell , vol.144 , Issue.6 , pp. 940-954
    • Young, R.A.1
  • 20
    • 39149130361 scopus 로고    scopus 로고
    • Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming
    • DOI 10.1016/j.cell.2008.01.015, PII S0092867408001153
    • Jaenisch R, Young R (2008) Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132(4):567-582. (Pubitemid 351253686)
    • (2008) Cell , vol.132 , Issue.4 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 21
    • 79955615662 scopus 로고    scopus 로고
    • The transcriptional and signalling networks of pluripotency
    • Ng HH, Surani MA (2011) The transcriptional and signalling networks of pluripotency. Nat Cell Biol 13(5):490-496.
    • (2011) Nat Cell Biol , vol.13 , Issue.5 , pp. 490-496
    • Ng, H.H.1    Surani, M.A.2
  • 22
    • 79958252915 scopus 로고    scopus 로고
    • Chromatin connections to pluripotency and cellular reprogramming
    • Orkin SH, Hochedlinger K (2011) Chromatin connections to pluripotency and cellular reprogramming. Cell 145(6):835-850.
    • (2011) Cell , vol.145 , Issue.6 , pp. 835-850
    • Orkin, S.H.1    Hochedlinger, K.2
  • 23
    • 79961002967 scopus 로고    scopus 로고
    • esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function
    • Ho L, et al. (2011) esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function. Nat Cell Biol 13(8):903-913.
    • (2011) Nat Cell Biol , vol.13 , Issue.8 , pp. 903-913
    • Ho, L.1
  • 24
    • 84860378636 scopus 로고    scopus 로고
    • Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity
    • Freudenberg JM, et al. (2012) Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity. Nucleic Acids Res 40(8):3364-3377.
    • (2012) Nucleic Acids Res , vol.40 , Issue.8 , pp. 3364-3377
    • Freudenberg, J.M.1
  • 25
    • 76249119007 scopus 로고    scopus 로고
    • Opposing microRNA families regulate self-renewal in mouse embryonic stem cells
    • Melton C, Judson RL, Blelloch R (2010) Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature 463(7281):621-626.
    • (2010) Nature , vol.463 , Issue.7281 , pp. 621-626
    • Melton, C.1    Judson, R.L.2    Blelloch, R.3
  • 26
    • 48449084118 scopus 로고    scopus 로고
    • Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
    • Marson A, et al. (2008) Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 134(3):521-533.
    • (2008) Cell , vol.134 , Issue.3 , pp. 521-533
    • Marson, A.1
  • 27
    • 56749091922 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation
    • Wang Y, et al. (2008) Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet 40(12):1478-1483.
    • (2008) Nat Genet , vol.40 , Issue.12 , pp. 1478-1483
    • Wang, Y.1
  • 28
    • 77950866324 scopus 로고    scopus 로고
    • Zscan4 regulates telomere elongation and genomic stability in ES cells
    • Zalzman M, et al. (2010) Zscan4 regulates telomere elongation and genomic stability in ES cells. Nature 464(7290):858-863.
    • (2010) Nature , vol.464 , Issue.7290 , pp. 858-863
    • Zalzman, M.1
  • 29
    • 70350686180 scopus 로고    scopus 로고
    • SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
    • Bilodeau S, Kagey MH, Frampton GM, Rahl PB, Young RA (2009) SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state. Genes Dev 23(21):2484-2489.
    • (2009) Genes Dev , vol.23 , Issue.21 , pp. 2484-2489
    • Bilodeau, S.1    Kagey, M.H.2    Frampton, G.M.3    Rahl, P.B.4    Young, R.A.5
  • 30
    • 4344571581 scopus 로고    scopus 로고
    • Rank products: A simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments
    • DOI 10.1016/j.febslet.2004.07.055, PII S0014579304009354
    • Breitling R, Armengaud P, Amtmann A, Herzyk P (2004) Rank products: A simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. FEBS Lett 573(1-3):83-92. (Pubitemid 39141040)
    • (2004) FEBS Letters , vol.573 , Issue.1-3 , pp. 83-92
    • Breitling, R.1    Armengaud, P.2    Amtmann, A.3    Herzyk, P.4
  • 31
    • 84875609093 scopus 로고    scopus 로고
    • A central role for TFIID in the pluripotent transcription circuitry
    • Pijnappel WW, et al. (2013) A central role for TFIID in the pluripotent transcription circuitry. Nature 495(7442):516-519.
    • (2013) Nature , vol.495 , Issue.7442 , pp. 516-519
    • Pijnappel, W.W.1
  • 32
    • 84870945375 scopus 로고    scopus 로고
    • Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system
    • Buckley SM, et al. (2012) Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system. Cell Stem Cell 11(6):783-798.
    • (2012) Cell Stem Cell , vol.11 , Issue.6 , pp. 783-798
    • Buckley, S.M.1
  • 33
    • 77957139539 scopus 로고    scopus 로고
    • Mediator and cohesin connect gene expression and chromatin architecture
    • Kagey MH, et al. (2010) Mediator and cohesin connect gene expression and chromatin architecture. Nature 467(7314):430-435.
    • (2010) Nature , vol.467 , Issue.7314 , pp. 430-435
    • Kagey, M.H.1
  • 34
    • 65249180173 scopus 로고    scopus 로고
    • An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
    • Ho L, et al. (2009) An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proc Natl Acad Sci USA 106(13):5181-5186.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.13 , pp. 5181-5186
    • Ho, L.1
  • 35
    • 65249173999 scopus 로고    scopus 로고
    • An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network
    • Ho L, et al. (2009) An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proc Natl Acad Sci USA 106(13):5187-5191.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.13 , pp. 5187-5191
    • Ho, L.1
  • 36
    • 84868017494 scopus 로고    scopus 로고
    • Regulation of pluripotency and self- renewal of ESCs through epigenetic-threshold modulation and mRNA pruning
    • Jia J, et al. (2012) Regulation of pluripotency and self- renewal of ESCs through epigenetic-threshold modulation and mRNA pruning. Cell 151(3):576-589.
    • (2012) Cell , vol.151 , Issue.3 , pp. 576-589
    • Jia, J.1
  • 37
    • 0038100185 scopus 로고    scopus 로고
    • Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
    • DOI 10.1038/nature01646
    • Takahashi K, Mitsui K, Yamanaka S (2003) Role of ERas in promoting tumour-like properties in mouse embryonic stem cells. Nature 423(6939):541-545. (Pubitemid 36648578)
    • (2003) Nature , vol.423 , Issue.6939 , pp. 541-545
    • Takahashi, K.1    Mitsui, K.2    Yamanaka, S.3
  • 38
    • 33846681638 scopus 로고    scopus 로고
    • Nucleolin: A multiFACeTed protein
    • DOI 10.1016/j.tcb.2006.11.010, PII S0962892406003370
    • Mongelard F, Bouvet P (2007) Nucleolin: A multiFACeTed protein. Trends Cell Biol 17(2):80-86. (Pubitemid 46199181)
    • (2007) Trends in Cell Biology , vol.17 , Issue.2 , pp. 80-86
    • Mongelard, F.1    Bouvet, P.2
  • 39
    • 84863433062 scopus 로고    scopus 로고
    • RNA-binding protein nucleolin in disease
    • Abdelmohsen K, Gorospe M (2012) RNA-binding protein nucleolin in disease. RNA Biol 9(6):799-808.
    • (2012) RNA Biol , vol.9 , Issue.6 , pp. 799-808
    • Abdelmohsen, K.1    Gorospe, M.2
  • 40
  • 41
    • 39149122855 scopus 로고    scopus 로고
    • Capturing pluripotency
    • Silva J, Smith A (2008) Capturing pluripotency. Cell 132(4):532 -536.
    • (2008) Cell , vol.132 , Issue.4 , pp. 532-536
    • Silva, J.1    Smith, A.2
  • 42
    • 83355163391 scopus 로고    scopus 로고
    • Nucleolin maintains embryonic stem cell self-renewal by suppression of p53 protein-dependent pathway
    • Yang A, et al. (2011) Nucleolin maintains embryonic stem cell self-renewal by suppression of p53 protein-dependent pathway. J Biol Chem 286(50):43370-43382.
    • (2011) J Biol Chem , vol.286 , Issue.50 , pp. 43370-43382
    • Yang, A.1
  • 44
    • 26244459242 scopus 로고    scopus 로고
    • Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin
    • DOI 10.1016/j.cell.2005.07.034, PII S0092867405008147
    • Takagi M, Absalon MJ, McLure KG, Kastan MB (2005) Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin. Cell 123(1):49-63. (Pubitemid 41414528)
    • (2005) Cell , vol.123 , Issue.1 , pp. 49-63
    • Takagi, M.1    Absalon, M.J.2    McLure, K.G.3    Kastan, M.B.4
  • 45
    • 84857483281 scopus 로고    scopus 로고
    • p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells
    • Jain AK, et al. (2012) p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells. PLoS Biol 10(2):e1001268.
    • (2012) PLoS Biol , vol.10 , Issue.2
    • Jain, A.K.1
  • 46
    • 69349098834 scopus 로고    scopus 로고
    • Stem cells: The promises and perils of p53
    • Krizhanovsky V, Lowe SW (2009) Stem cells: The promises and perils of p53. Nature 460(7259):1085-1086.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1085-1086
    • Krizhanovsky, V.1    Lowe, S.W.2
  • 47
    • 84862777719 scopus 로고    scopus 로고
    • Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells
    • Li M, et al. (2012) Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells. Mol Cell 46(1):30-42.
    • (2012) Mol Cell , vol.46 , Issue.1 , pp. 30-42
    • Li, M.1
  • 48
    • 41149105243 scopus 로고    scopus 로고
    • ROS and p53: A versatile partnership
    • Liu B, Chen Y, St Clair DK (2008) ROS and p53: A versatile partnership. Free Radic Biol Med 44(8):1529-1535.
    • (2008) Free Radic Biol Med , vol.44 , Issue.8 , pp. 1529-1535
    • Liu, B.1    Chen, Y.2    St Clair, D.K.3
  • 49
    • 44349170450 scopus 로고    scopus 로고
    • The ground state of embryonic stem cell self-renewal
    • Ying QL, et al. (2008) The ground state of embryonic stem cell self-renewal. Nature 453(7194):519-523.
    • (2008) Nature , vol.453 , Issue.7194 , pp. 519-523
    • Ying, Q.L.1
  • 50
    • 73049112178 scopus 로고    scopus 로고
    • Vitamin C enhances the generation of mouse and human induced pluripotent stem cells
    • Esteban MA, et al. (2010) Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell 6(1):71-79.
    • (2010) Cell Stem Cell , vol.6 , Issue.1 , pp. 71-79
    • Esteban, M.A.1
  • 51
    • 0020444895 scopus 로고
    • Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis
    • Griffith OW (1982) Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis. J Biol Chem 257(22):13704-13712.
    • (1982) J Biol Chem , vol.257 , Issue.22 , pp. 13704-13712
    • Griffith, O.W.1
  • 53
    • 77249176666 scopus 로고    scopus 로고
    • p53 and stem cells: New developments and new concerns
    • Zhao T, Xu Y (2010) p53 and stem cells: New developments and new concerns. Trends Cell Biol 20(3):170-175.
    • (2010) Trends Cell Biol , vol.20 , Issue.3 , pp. 170-175
    • Zhao, T.1    Xu, Y.2
  • 55
    • 84864631288 scopus 로고    scopus 로고
    • Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling
    • Lee DF, et al. (2012) Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling. Cell Stem Cell 11(2):179-194.
    • (2012) Cell Stem Cell , vol.11 , Issue.2 , pp. 179-194
    • Lee, D.F.1
  • 56
    • 39749087530 scopus 로고    scopus 로고
    • SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
    • Han MK, et al. (2008) SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell 2(3):241-251.
    • (2008) Cell Stem Cell , vol.2 , Issue.3 , pp. 241-251
    • Han, M.K.1
  • 58
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • DOI 10.1038/ng.127, PII NG127
    • Ben-Porath I, et al. (2008) An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 40(5):499-507. (Pubitemid 351601215)
    • (2008) Nature Genetics , vol.40 , Issue.5 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 59
    • 77955428416 scopus 로고    scopus 로고
    • NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53
    • Zbinden M, et al. (2010) NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. EMBO J 29(15):2659-2674.
    • (2010) EMBO J , vol.29 , Issue.15 , pp. 2659-2674
    • Zbinden, M.1
  • 60
    • 64749093574 scopus 로고    scopus 로고
    • Association of reactive oxygen species levels and radioresistance in cancer stem cells
    • Diehn M, et al. (2009) Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 458(7239):780-783.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 780-783
    • Diehn, M.1
  • 61
    • 84865095919 scopus 로고    scopus 로고
    • A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers
    • Palmer NP, Schmid PR, Berger B, Kohane IS (2012) A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers. Genome Biol 13(8):R71.
    • (2012) Genome Biol , vol.13 , Issue.8
    • Palmer, N.P.1    Schmid, P.R.2    Berger, B.3    Kohane, I.S.4
  • 62
    • 33751006151 scopus 로고    scopus 로고
    • RankProd: A bioconductor package for detecting differentially expressed genes in meta-analysis
    • DOI 10.1093/bioinformatics/btl476
    • Hong F, et al. (2006) RankProd: A bioconductor package for detecting differentially expressed genes in meta-analysis. Bioinformatics 22(22):2825-2827. (Pubitemid 44742407)
    • (2006) Bioinformatics , vol.22 , Issue.22 , pp. 2825-2827
    • Hong, F.1    Breitling, R.2    McEntee, C.W.3    Wittner, B.S.4    Nemhauser, J.L.5    Chory, J.6
  • 63
    • 79960277368 scopus 로고    scopus 로고
    • Optimally weighted Z-test is a powerful method for combining probabilities in meta-analysis
    • Zaykin DV (2011) Optimally weighted Z-test is a powerful method for combining probabilities in meta-analysis. J Evol Biol 24(8):1836-1841.
    • (2011) J Evol Biol , vol.24 , Issue.8 , pp. 1836-1841
    • Zaykin, D.V.1
  • 64
    • 33845275018 scopus 로고    scopus 로고
    • RIP-Chip: The isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts
    • Keene JD, Komisarow JM, Friedersdorf MB (2006) RIP-Chip: The isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts. Nat Protoc 1(1):302-307.
    • (2006) Nat Protoc , vol.1 , Issue.1 , pp. 302-307
    • Keene, J.D.1    Komisarow, J.M.2    Friedersdorf, M.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.