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Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 9, 2014, Pages 2134-2136

Highly accurate synthesis of the fully 2′-fluoro-modified oligonucleotide by Therminator DNA polymerases

(4) Kasuya, Takeshi a Hori, Shinichiro a Hiramatsu, Hisanao a Yanagimoto, Toru a

a SHIONOGI AND CO LTD (Japan)

Author keywords

2 Fluoro NTP; Biosynthesis; DNA polymerase; Fidelity; Oligonucleotide

Indexed keywords

2' SUGAR MODIFIED NUCLEOSIDE 5' TRIPHOSPHATE DERIVATIVE; DEOXYRIBONUCLEASE I; DNA POLYMERASE; DNA POLYMERASE REV1; OLIGONUCLEOTIDE; RNA POLYMERASE; THERMINATOR DNA POLYMERASE; UNCLASSIFIED DRUG; DNA FRAGMENT; RNA; DNA DIRECTED DNA POLYMERASE;

ARTICLE; CONTROLLED STUDY; DNA TEMPLATE; ELECTROPHORESIS; ENZYME ACTIVE SITE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION; SEQUENCE ANALYSIS; SYNTHESIS; THERMOCOCCUS; DNA SEQUENCE; DRUG STRUCTURE; DRUG SYNTHESIS; RNA SYNTHESIS; ARCHAEON; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; HALOGENATION; METABOLISM; MOLECULAR GENETICS;

ARCHAEA; BASE SEQUENCE; DNA-DIRECTED DNA POLYMERASE; HALOGENATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; RNA;

EID: 84899070606 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2014.03.035 Document Type: Article

Times cited : (6)

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