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Volumn 30, Issue 5 S, 2014, Pages S3-

β-Adrenoceptors as molecular targets in the treatment of hypertension

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ARRESTIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOPAMINE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; LEUKOTRIENE; MITOGEN ACTIVATED PROTEIN KINASE 3; PARTIAL AGONIST; PROSTANOID; THROMBOXANE A2; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOCONSTRICTOR AGENT; VASOPRESSIN;

EID: 84899062131     PISSN: 0828282X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cjca.2014.01.017     Document Type: Review
Times cited : (19)

References (57)
  • 2
    • 0004397581 scopus 로고
    • Total Thoracic and Partial to Total Lumbar Sympathectomy and Celiac Ganglionectomy in the Treatment of Hypertension
    • Grimson K.S. Total Thoracic and Partial to Total Lumbar Sympathectomy and Celiac Ganglionectomy in the Treatment of Hypertension. Ann Surg 1941, 114:753-775.
    • (1941) Ann Surg , vol.114 , pp. 753-775
    • Grimson, K.S.1
  • 4
    • 0029803532 scopus 로고    scopus 로고
    • Overview of alpha 1-adrenoceptor antagonism and recent advances in hypertensive therapy
    • Veelken R., Schmieder R.E. Overview of alpha 1-adrenoceptor antagonism and recent advances in hypertensive therapy. Am J Hypertens 1996, 9:139S-149S.
    • (1996) Am J Hypertens , vol.9
    • Veelken, R.1    Schmieder, R.E.2
  • 5
    • 0034724098 scopus 로고    scopus 로고
    • National Heart, Lung, and Blood Institute halts part of antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)
    • SoRelle R. National Heart, Lung, and Blood Institute halts part of antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). Circulation 2000, 101:E9025.
    • (2000) Circulation , vol.101
    • SoRelle, R.1
  • 6
    • 0034685403 scopus 로고    scopus 로고
    • Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). ALLHAT Collaborative Research Group
    • Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). ALLHAT Collaborative Research Group. JAMA 2000, 283:1967-1975.
    • (2000) JAMA , vol.283 , pp. 1967-1975
  • 7
    • 84876814906 scopus 로고    scopus 로고
    • The 2013 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension
    • Hackam D.G., Quinn R.R., Ravani P., et al. The 2013 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. Can J Cardiol 2013, 29:528-542.
    • (2013) Can J Cardiol , vol.29 , pp. 528-542
    • Hackam, D.G.1    Quinn, R.R.2    Ravani, P.3
  • 8
    • 84860898882 scopus 로고    scopus 로고
    • The evolving role of β-adrenergic receptor blockers in managing hypertension
    • Poirier L., Lacourciere Y. The evolving role of β-adrenergic receptor blockers in managing hypertension. Can J Cardiol 2012, 28:334-340.
    • (2012) Can J Cardiol , vol.28 , pp. 334-340
    • Poirier, L.1    Lacourciere, Y.2
  • 9
    • 0023808883 scopus 로고
    • The functional importance of beta 1 and beta 2 adrenoceptors in the human heart
    • Brodde O.E. The functional importance of beta 1 and beta 2 adrenoceptors in the human heart. Am J Cardiol 1988, 62:24C-29C.
    • (1988) Am J Cardiol , vol.62
    • Brodde, O.E.1
  • 10
    • 29544449036 scopus 로고    scopus 로고
    • Molecular mechanisms of beta(2)-adrenergic receptor function, response, and regulation
    • quiz 25
    • Johnson M. Molecular mechanisms of beta(2)-adrenergic receptor function, response, and regulation. JAllergy Clin Immunol 2006, 117:18-24. quiz 25.
    • (2006) JAllergy Clin Immunol , vol.117 , pp. 18-24
    • Johnson, M.1
  • 11
    • 0141792382 scopus 로고    scopus 로고
    • Place of beta 3-adrenoceptors among other beta-adrenoceptor subtypes in the regulation of the cardiovascular system
    • Rozec B., Noireaud J., Trochu J.N., Gauthier C. Place of beta 3-adrenoceptors among other beta-adrenoceptor subtypes in the regulation of the cardiovascular system. Arch Mal Coeur Vaiss 2003, 96:905-913.
    • (2003) Arch Mal Coeur Vaiss , vol.96 , pp. 905-913
    • Rozec, B.1    Noireaud, J.2    Trochu, J.N.3    Gauthier, C.4
  • 12
    • 7544221319 scopus 로고    scopus 로고
    • Structure and function of beta3-adrenergic receptors
    • Skeberdis V.A. Structure and function of beta3-adrenergic receptors. Medicina (Kaunas) 2004, 40:407-413.
    • (2004) Medicina (Kaunas) , vol.40 , pp. 407-413
    • Skeberdis, V.A.1
  • 13
    • 0023296340 scopus 로고
    • Beta-adrenergic receptor-coupled adenylate cyclase. Biochemical mechanisms of regulation
    • Sibley D.R., Lefkowitz R.J. Beta-adrenergic receptor-coupled adenylate cyclase. Biochemical mechanisms of regulation. Mol Neurobiol 1987, 1:121-154.
    • (1987) Mol Neurobiol , vol.1 , pp. 121-154
    • Sibley, D.R.1    Lefkowitz, R.J.2
  • 14
    • 0022485749 scopus 로고
    • Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin
    • Dixon R.A., Kobilka B.K., Strader D.J., et al. Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. Nature 1986, 321:75-79.
    • (1986) Nature , vol.321 , pp. 75-79
    • Dixon, R.A.1    Kobilka, B.K.2    Strader, D.J.3
  • 15
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander E.S., Linton L.M., Birren B., et al. Initial sequencing and analysis of the human genome. Nature 2001, 409:860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3
  • 16
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter J.C., Adams M.D., Myers E.W., et al. The sequence of the human genome. Science 2001, 291:1304-1351.
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2    Myers, E.W.3
  • 17
    • 36248970132 scopus 로고    scopus 로고
    • Crystal structure of the human beta2 adrenergic G-protein-coupled receptor
    • Rasmussen S.G., Choi H.J., Rosenbaum D.M., et al. Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature 2007, 450:383-387.
    • (2007) Nature , vol.450 , pp. 383-387
    • Rasmussen, S.G.1    Choi, H.J.2    Rosenbaum, D.M.3
  • 18
    • 78651399683 scopus 로고    scopus 로고
    • Structure and function of an irreversible agonist-beta(2) adrenoceptor complex
    • Rosenbaum D.M., Zhang C., Lyons J.A., et al. Structure and function of an irreversible agonist-beta(2) adrenoceptor complex. Nature 2011, 469:236-240.
    • (2011) Nature , vol.469 , pp. 236-240
    • Rosenbaum, D.M.1    Zhang, C.2    Lyons, J.A.3
  • 19
    • 80051658642 scopus 로고    scopus 로고
    • Crystal structure of the beta2 adrenergic receptor-Gs protein complex
    • Rasmussen S.G., DeVree B.T., Zou Y., et al. Crystal structure of the beta2 adrenergic receptor-Gs protein complex. Nature 2011, 477:549-555.
    • (2011) Nature , vol.477 , pp. 549-555
    • Rasmussen, S.G.1    DeVree, B.T.2    Zou, Y.3
  • 20
    • 80053357815 scopus 로고    scopus 로고
    • Conformational changes in the G protein Gs induced by the beta2 adrenergic receptor
    • Chung K.Y., Rasmussen S.G., Liu T., et al. Conformational changes in the G protein Gs induced by the beta2 adrenergic receptor. Nature 2011, 477:611-615.
    • (2011) Nature , vol.477 , pp. 611-615
    • Chung, K.Y.1    Rasmussen, S.G.2    Liu, T.3
  • 21
    • 79961051091 scopus 로고    scopus 로고
    • Taking the heart failure battle inside the cell: small molecule targeting of G βλ subunits
    • Kamal F.A., Smrcka A.V., Blaxall B.C. Taking the heart failure battle inside the cell: small molecule targeting of G βλ subunits. J Mol Cell Cardiol 2011, 51:462-467.
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 462-467
    • Kamal, F.A.1    Smrcka, A.V.2    Blaxall, B.C.3
  • 22
    • 0030460743 scopus 로고    scopus 로고
    • G-protein-coupled receptor regulation: role of GRK receptor kinases and arrestins
    • Ferguson S.S., Barak L.S., Zhang J., Caron M.G. G-protein-coupled receptor regulation: role of GRK receptor kinases and arrestins. Can J Physiol Pharmacol 1996, 74:1095-1110.
    • (1996) Can J Physiol Pharmacol , vol.74 , pp. 1095-1110
    • Ferguson, S.S.1    Barak, L.S.2    Zhang, J.3    Caron, M.G.4
  • 23
    • 0031747997 scopus 로고    scopus 로고
    • The role of receptor kinases and arrestins in G protein-coupled receptor regulation
    • Krupnick J.G., Benovic J.L. The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol 1998, 38:289-319.
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 289-319
    • Krupnick, J.G.1    Benovic, J.L.2
  • 24
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling
    • Ferguson S.S. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 2001, 53:1-24.
    • (2001) Pharmacol Rev , vol.53 , pp. 1-24
    • Ferguson, S.S.1
  • 25
    • 0036473397 scopus 로고    scopus 로고
    • The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals
    • Luttrell L.M., Lefkowitz R.J. The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. JCell Sci 2002, 115(pt 3):455-465.
    • (2002) JCell Sci , vol.115 , Issue.PART 3 , pp. 455-465
    • Luttrell, L.M.1    Lefkowitz, R.J.2
  • 26
    • 0027471763 scopus 로고
    • The human beta 3-adrenergic receptor is resistant to short term agonist-promoted desensitization
    • Nantel F., Bonin H., Emorine L.J., et al. The human beta 3-adrenergic receptor is resistant to short term agonist-promoted desensitization. Mol Pharmacol 1993, 43:548-555.
    • (1993) Mol Pharmacol , vol.43 , pp. 548-555
    • Nantel, F.1    Bonin, H.2    Emorine, L.J.3
  • 27
    • 77952415656 scopus 로고    scopus 로고
    • Beyond desensitization: physiological relevance of arrestin-dependent signalling
    • Luttrell L.M., Gesty-Palmer D. Beyond desensitization: physiological relevance of arrestin-dependent signalling. Pharmacol Rev 2010, 62:305-330.
    • (2010) Pharmacol Rev , vol.62 , pp. 305-330
    • Luttrell, L.M.1    Gesty-Palmer, D.2
  • 28
    • 0030593035 scopus 로고    scopus 로고
    • Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization
    • Ferguson S.S., Downey W.E., Colapietro A.M., et al. Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 1996, 271:363-366.
    • (1996) Science , vol.271 , pp. 363-366
    • Ferguson, S.S.1    Downey, W.E.2    Colapietro, A.M.3
  • 29
    • 0029770657 scopus 로고    scopus 로고
    • Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor
    • Goodman O.B., Krupnick J.G., Santini F., et al. Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature 1996, 383:447-450.
    • (1996) Nature , vol.383 , pp. 447-450
    • Goodman, O.B.1    Krupnick, J.G.2    Santini, F.3
  • 30
    • 0033616494 scopus 로고    scopus 로고
    • The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis
    • Laporte S.A., Oakley R.H., Zhang J., et al. The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis. Proc Natl Acad Sci U S A 1999, 96:3712-3717.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 3712-3717
    • Laporte, S.A.1    Oakley, R.H.2    Zhang, J.3
  • 31
    • 0033613938 scopus 로고    scopus 로고
    • Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes
    • Luttrell L.M., Ferguson S.S., Daaka Y., et al. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science 1999, 283:655-661.
    • (1999) Science , vol.283 , pp. 655-661
    • Luttrell, L.M.1    Ferguson, S.S.2    Daaka, Y.3
  • 32
    • 0035956983 scopus 로고    scopus 로고
    • Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds
    • Luttrell L.M., Roudabush F.L., Choy E.W., et al. Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds. Proc Natl Acad Sci U S A 2001, 98:2449-2454.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2449-2454
    • Luttrell, L.M.1    Roudabush, F.L.2    Choy, E.W.3
  • 33
    • 0037088585 scopus 로고    scopus 로고
    • Beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation
    • Tohgo A., Pierce K.L., Choy E.W., Lefkowitz R.J., Luttrell L.M. beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation. JBiol Chem 2002, 277:9429-9436.
    • (2002) JBiol Chem , vol.277 , pp. 9429-9436
    • Tohgo, A.1    Pierce, K.L.2    Choy, E.W.3    Lefkowitz, R.J.4    Luttrell, L.M.5
  • 34
    • 0034711397 scopus 로고    scopus 로고
    • Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3
    • McDonald P.H., Chow C.W., Miller W.E., et al. Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science 2000, 290:1574-1577.
    • (2000) Science , vol.290 , pp. 1574-1577
    • McDonald, P.H.1    Chow, C.W.2    Miller, W.E.3
  • 35
    • 22744449073 scopus 로고    scopus 로고
    • An Akt/beta-arrestin 2/PP2A signalling complex mediates dopaminergic neurotransmission and behavior
    • Beaulieu J.M., Sotnikova T.D., Marion S., et al. An Akt/beta-arrestin 2/PP2A signalling complex mediates dopaminergic neurotransmission and behavior. Cell 2005, 122:261-273.
    • (2005) Cell , vol.122 , pp. 261-273
    • Beaulieu, J.M.1    Sotnikova, T.D.2    Marion, S.3
  • 36
    • 0035834775 scopus 로고    scopus 로고
    • Beta-Arrestin-mediated ADP-ribosylation factor 6 activation and beta 2-adrenergic receptor endocytosis
    • Claing A., Chen W., Miller W.E., et al. beta-Arrestin-mediated ADP-ribosylation factor 6 activation and beta 2-adrenergic receptor endocytosis. JBiol Chem 2001, 276:42509-42513.
    • (2001) JBiol Chem , vol.276 , pp. 42509-42513
    • Claing, A.1    Chen, W.2    Miller, W.E.3
  • 37
    • 14844338481 scopus 로고    scopus 로고
    • Beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation
    • Barnes W.G., Reiter E., Violin J.D., et al. beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation. JBiol Chem 2005, 280:8041-8050.
    • (2005) JBiol Chem , vol.280 , pp. 8041-8050
    • Barnes, W.G.1    Reiter, E.2    Violin, J.D.3
  • 38
    • 18544379729 scopus 로고    scopus 로고
    • Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization
    • Bhattacharya M., Anborgh P.H., Babwah A.V., et al. Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization. Nat Cell Biol 2002, 4:547-555.
    • (2002) Nat Cell Biol , vol.4 , pp. 547-555
    • Bhattacharya, M.1    Anborgh, P.H.2    Babwah, A.V.3
  • 39
    • 0034705116 scopus 로고    scopus 로고
    • The ADP ribosylation factor nucleotide exchange factor ARNO promotes beta-arrestin release necessary for luteinizing hormone/choriogonadotropin receptor desensitization
    • Mukherjee S., Gurevich V.V., Jones J.C., et al. The ADP ribosylation factor nucleotide exchange factor ARNO promotes beta-arrestin release necessary for luteinizing hormone/choriogonadotropin receptor desensitization. Proc Natl Acad Sci U S A 2000, 97:5901-5906.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 5901-5906
    • Mukherjee, S.1    Gurevich, V.V.2    Jones, J.C.3
  • 40
    • 80054727295 scopus 로고    scopus 로고
    • Refining efficacy: Allosterism and bias in G protein-coupled receptor signaling
    • Luttrell L., Kenakin T. Refining efficacy: Allosterism and bias in G protein-coupled receptor signaling. Methods Mol Biol 2011, 756:3-35.
    • (2011) Methods Mol Biol , vol.756 , pp. 3-35
    • Luttrell, L.1    Kenakin, T.2
  • 41
    • 36348946976 scopus 로고    scopus 로고
    • Functional selectivity through protean and biased agonism: who steers the ship?
    • Kenakin T. Functional selectivity through protean and biased agonism: who steers the ship?. Mol Pharmacol 2007, 72:1393-1401.
    • (2007) Mol Pharmacol , vol.72 , pp. 1393-1401
    • Kenakin, T.1
  • 42
    • 34447642715 scopus 로고    scopus 로고
    • The evasive nature of drug efficacy: implications for drug discovery
    • Galandrin S., Oligny-Longpre G., Bouvier M. The evasive nature of drug efficacy: implications for drug discovery. Trends Pharmacol Sci 2007, 28:423-430.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 423-430
    • Galandrin, S.1    Oligny-Longpre, G.2    Bouvier, M.3
  • 43
    • 84880675341 scopus 로고    scopus 로고
    • Measurements of ligand bias and functional affinity
    • Kenakin T., Christopoulos A. Measurements of ligand bias and functional affinity. Nat Rev Drug Discov 2013, 12:483.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 483
    • Kenakin, T.1    Christopoulos, A.2
  • 44
    • 36749094552 scopus 로고    scopus 로고
    • Aunique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling
    • Wisler J.W., DeWire S.M., Whalen E.J., et al. Aunique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling. Proc Natl Acad Sci U S A 2007, 104:16657-16662.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 16657-16662
    • Wisler, J.W.1    DeWire, S.M.2    Whalen, E.J.3
  • 45
    • 38349118001 scopus 로고    scopus 로고
    • Role of beta-arrestin-mediated desensitization and signaling in the control of angiotensin AT1a receptor-stimulated transcription
    • Lee M.H., El-Shewy H.M., Luttrell D.K., Luttrell L.M. Role of beta-arrestin-mediated desensitization and signaling in the control of angiotensin AT1a receptor-stimulated transcription. JBiol Chem 2008, 283:2088-2097.
    • (2008) JBiol Chem , vol.283 , pp. 2088-2097
    • Lee, M.H.1    El-Shewy, H.M.2    Luttrell, D.K.3    Luttrell, L.M.4
  • 46
    • 77958039571 scopus 로고    scopus 로고
    • Energy landscapes as a tool to integrate GPCR structure, dynamics, and function
    • Deupi X., Kobilka B.K. Energy landscapes as a tool to integrate GPCR structure, dynamics, and function. Physiology (Bethesda) 2010, 25:293-303.
    • (2010) Physiology (Bethesda) , vol.25 , pp. 293-303
    • Deupi, X.1    Kobilka, B.K.2
  • 47
    • 0025641381 scopus 로고
    • Increased regional sympathetic nervous activity in human hypertension: causes and consequences
    • Esler M., Lambert G., Jennings G. Increased regional sympathetic nervous activity in human hypertension: causes and consequences. JHypertens Suppl 1990, 8:S53-S57.
    • (1990) JHypertens Suppl , vol.8
    • Esler, M.1    Lambert, G.2    Jennings, G.3
  • 48
    • 33646773571 scopus 로고    scopus 로고
    • Defective vasodilatory mechanisms in hypertension: a G-protein-coupled receptor perspective
    • Feldman R.D., Gros R. Defective vasodilatory mechanisms in hypertension: a G-protein-coupled receptor perspective. Curr Opin Nephrol Hypertens 2006, 15:135-140.
    • (2006) Curr Opin Nephrol Hypertens , vol.15 , pp. 135-140
    • Feldman, R.D.1    Gros, R.2
  • 49
    • 0032191117 scopus 로고    scopus 로고
    • Impaired vasodilator function in hypertension: the role of alterations in receptor-G protein coupling
    • Feldman R.D., Gros R. Impaired vasodilator function in hypertension: the role of alterations in receptor-G protein coupling. Trends Cardiovasc Med 1998, 8:297-305.
    • (1998) Trends Cardiovasc Med , vol.8 , pp. 297-305
    • Feldman, R.D.1    Gros, R.2
  • 50
    • 0025830940 scopus 로고
    • Cardiac performance in elderly hypertensive patients with left ventricular hypertrophy: responses to isometric exercise and beta-agonists
    • Suzuki Y., Kuwajima I., Hoshino S., et al. Cardiac performance in elderly hypertensive patients with left ventricular hypertrophy: responses to isometric exercise and beta-agonists. JCardiovasc Pharmacol 1991, 17(suppl 2):S129-S132.
    • (1991) JCardiovasc Pharmacol , vol.17 , Issue.SUPPL. 2
    • Suzuki, Y.1    Kuwajima, I.2    Hoshino, S.3
  • 51
    • 0027223098 scopus 로고
    • Catecholamines and essential hypertension
    • Esler M.D. Catecholamines and essential hypertension. Baillieres Clin Endocrinol Metab 1993, 7:415-438.
    • (1993) Baillieres Clin Endocrinol Metab , vol.7 , pp. 415-438
    • Esler, M.D.1
  • 52
    • 0020673352 scopus 로고
    • Plasma catecholamines and essential hypertension. An analytical review
    • Goldstein D.S. Plasma catecholamines and essential hypertension. An analytical review. Hypertension 1983, 5:86-99.
    • (1983) Hypertension , vol.5 , pp. 86-99
    • Goldstein, D.S.1
  • 54
    • 0023393160 scopus 로고
    • Beta-adrenergic receptor alterations in hypertension-physiological and molecular correlates
    • Feldman R.D. Beta-adrenergic receptor alterations in hypertension-physiological and molecular correlates. Can J Physiol Pharmacol 1987, 65:1666-1672.
    • (1987) Can J Physiol Pharmacol , vol.65 , pp. 1666-1672
    • Feldman, R.D.1
  • 55
    • 0031000256 scopus 로고    scopus 로고
    • G-protein-coupled receptor kinase activity is increased in hypertension
    • Gros R., Benovic J.L., Tan C.M., Feldman R.D. G-protein-coupled receptor kinase activity is increased in hypertension. JClin Invest 1997, 99:2087-2093.
    • (1997) JClin Invest , vol.99 , pp. 2087-2093
    • Gros, R.1    Benovic, J.L.2    Tan, C.M.3    Feldman, R.D.4
  • 56
    • 0023108267 scopus 로고
    • Low sodium diet corrects the defect in lymphocyte beta-adrenergic responsiveness in hypertensive subjects
    • Feldman R.D., Lawton W.J., McArdle W.L. Low sodium diet corrects the defect in lymphocyte beta-adrenergic responsiveness in hypertensive subjects. JClin Invest 1987, 79:290-294.
    • (1987) JClin Invest , vol.79 , pp. 290-294
    • Feldman, R.D.1    Lawton, W.J.2    McArdle, W.L.3
  • 57
    • 0025261231 scopus 로고
    • Defective venous beta-adrenergic response in borderline hypertensive subjects is corrected by a low sodium diet
    • Feldman R.D. Defective venous beta-adrenergic response in borderline hypertensive subjects is corrected by a low sodium diet. JClin Invest 1990, 85:647-652.
    • (1990) JClin Invest , vol.85 , pp. 647-652
    • Feldman, R.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.