A random sequential mechanism of aminoglycoside acetylation by Mycobacterium tuberculosis Eis protein

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Tsodikov, Oleg V ^a   Green, Keith D ^a   Garneau Tsodikova, Sylvie ^a  

^a University of Kentucky   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A; AMINOGLYCOSIDE ANTIBIOTIC AGENT; BACTERIAL PROTEIN; ENHANCED INTRACELLULAR SURVIVAL PROTEIN; ENHANCED INTRACELLULAR SURVIVAL PROTEIN INHIBITOR; FRAMYCETIN; KANAMYCIN A; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; ACYLTRANSFERASE; AMINOGLYCOSIDE ACETYLTRANSFERASE; ANTIINFECTIVE AGENT; BACTERIAL ANTIGEN; EIS PROTEIN, MYCOBACTERIUM TUBERCULOSIS;

ANTIBIOTIC RESISTANCE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACETYLATION; DRUG DESIGN; ENZYME ASSAY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STEADY STATE; ACETYLATION; BINDING SITE; DRUG EFFECTS; ENZYME SPECIFICITY; KINETICS; METABOLISM;

ACETYL COENZYME A; ACETYLATION; ACETYLTRANSFERASES; ANTI-BACTERIAL AGENTS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BINDING SITES; FRAMYCETIN; KINETICS; SUBSTRATE SPECIFICITY;

EID: 84899057652     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092370     Document Type: Article

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