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ChemBioChem

Volumn 14, Issue 16, 2013, Pages 2127-2135

Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase eis

(5) Houghton, Jacob L a Biswas, Tapan a Chen, Wenjing a Tsodikov, Oleg V b Garneau Tsodikova, Sylvie b

a UNIVERSITY OF MICHIGAN (United States)

b UNIVERSITY OF KENTUCKY (United States)

Author keywords

Bacterial resistance; Enhanced intracellular survival protein; Enzymatic reaction; Multi acetylation; Tuberculosis

Indexed keywords

ACYLTRANSFERASE; AMIKACIN; AMINOGLYCOSIDE; COENZYME A; INTRACELLULAR SURVIVAL PROTEIN; KANAMYCIN; NETILMICIN; SISOMICIN; TOBRAMYCIN; UNCLASSIFIED DRUG;

ACETYLATION; ANTIMICROBIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMPARATIVE STUDY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DISK DIFFUSION; DISULFIDE BOND; DRUG STRUCTURE; ESCHERICHIA COLI; HYDROGEN BOND; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; THIN LAYER CHROMATOGRAPHY;

BACTERIA (MICROORGANISMS);

BACTERIAL RESISTANCE; ENHANCED INTRACELLULAR SURVIVAL PROTEIN; ENZYMATIC REACTION; MULTI-ACETYLATION; TUBERCULOSIS;

ACETYLATION; ACETYLTRANSFERASES; AMIKACIN; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BINDING SITES; CATALYTIC DOMAIN; COENZYME A; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, BACTERIAL; KANAMYCIN; MOLECULAR DYNAMICS SIMULATION; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; STEREOISOMERISM; TOBRAMYCIN;

EID: 84889590641 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201300359 Document Type: Article

Times cited : (53)

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