Kinetic mechanism of the GCN5-related chromosomal aminoglycoside acetyltransferase AAC(6′)-II from Enterococcus faecium: Evidence of dimer subunit cooperativity

Biochemistry

Volumn 42, Issue 21, 2003, Pages 6565-6574

  Draker, Kari Ann ^a   Northrop, Dexter B ^b   Wright, Gerard D ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; CATALYSIS; CHEMICAL MODIFICATION; CHROMOSOMES; DIMERS; ENZYME INHIBITION;

MICROBIAL RESISTANCE;

ENZYMES;

ACETYL COENZYME A; ACYLTRANSFERASE; AMINOGLYCOSIDE ACETYLTRANSFERASE; BACTERIAL ENZYME; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CALORIMETRY; CATALYSIS; CHROMOSOME; COMPLEX FORMATION; CONTROLLED STUDY; DIFFUSION; DIMERIZATION; DRUG BINDING; ENTEROCOCCUS FAECIUM; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN TRANSPORT; TITRIMETRY; VISCOSITY;

ACETYLTRANSFERASES; ALANINE; CALORIMETRY; DIFFUSION; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROCOCCUS FAECIUM; ESCHERICHIA COLI; KINETICS; MODELS, CHEMICAL; MULTIGENE FAMILY; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SOLVENTS; THERMODYNAMICS; TRYPTOPHAN;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS; ENTEROCOCCUS FAECIUM;

EID: 0038728733     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034148h     Document Type: Article

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