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Volumn 42, Issue 7, 2014, Pages 4196-4207

Physical constraints determine the logic of bacterial promoter architectures

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

EID: 84899024465     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku078     Document Type: Article
Times cited : (22)

References (74)
  • 1
    • 33846002036 scopus 로고    scopus 로고
    • Transcriptional regulation by competing transcription factor modules
    • DOI 10.1371/journal.pcbi.0020164
    • Hermsen, R., Tans, S. and ten Wolde, P.R. (2006) Transcriptional regulation by competing transcription factor modules. PLoS Comput. Biol., 2, 1552-1560. (Pubitemid 46045168)
    • (2006) PLoS Computational Biology , vol.2 , Issue.12 , pp. 1552-1560
    • Hermsen, R.1    Tans, S.2    Ten Wolde, P.R.3
  • 2
    • 0034072450 scopus 로고    scopus 로고
    • DNA binding sites: Representation and discovery
    • Stormo, G.D. (2000) DNA binding sites: representation and discovery. Bioinformatics, 16, 16-23. (Pubitemid 30204197)
    • (2000) Bioinformatics , vol.16 , Issue.1 , pp. 16-23
    • Stormo, G.D.1
  • 4
    • 0242574990 scopus 로고    scopus 로고
    • A biophysical approach to transcription factor binding site discovery
    • DOI 10.1101/gr.1271603
    • Djordjevic, M., Sengupta, A.M. and Shraiman, B.I. (2003) A biophysical approach to transcription factor binding site discovery. Genome Res., 13, 2381-2390. (Pubitemid 37428261)
    • (2003) Genome Research , vol.13 , Issue.11 , pp. 2381-2390
    • Djordjevic, M.1    Sengupta, A.M.2    Shraiman, B.I.3
  • 6
    • 33748191291 scopus 로고    scopus 로고
    • Statistical mechanical modeling of genome-wide transcription factor occupancy data by MatrixREDUCE
    • DOI 10.1093/bioinformatics/btl223
    • Foat, B.C., Morozov, A.V. and Bussemaker, H.J. (2006) Statistical mechanical modeling of genome-wide transcription factor occupancy data by MatrixREDUCE. Bioinformatics, 22, e141-e149. (Pubitemid 44307813)
    • (2006) Bioinformatics , vol.22 , Issue.14
    • Foat, B.C.1    Morozov, A.V.2    Bussemaker, H.J.3
  • 7
    • 33846700587 scopus 로고    scopus 로고
    • Predicting transcription factor affinities to DNA from a biophysical model
    • DOI 10.1093/bioinformatics/btl565
    • Roider, H.G., Kanhere, A., Manke, T. and Vingron, M. (2007) Predicting transcription factor affinities to DNA from a biophysical model. Bioinformatics, 23, 134-141. (Pubitemid 46189601)
    • (2007) Bioinformatics , vol.23 , Issue.2 , pp. 134-141
    • Roider, H.G.1    Kanhere, A.2    Manke, T.3    Vingron, M.4
  • 8
    • 61449155349 scopus 로고    scopus 로고
    • Models of transcription factor binding: Sensitivity of activation functions to model assumptions
    • Chu, D., Zabet, N.R. and Mitavskiy, B. (2009) Models of transcription factor binding: sensitivity of activation functions to model assumptions. J theor. Biol., 257, 419-429.
    • (2009) J theor. Biol. , vol.257 , pp. 419-429
    • Chu, D.1    Zabet, N.R.2    Mitavskiy, B.3
  • 9
    • 74549209548 scopus 로고    scopus 로고
    • Inferring binding energies from selected binding sites
    • Zhao, Y., Granas, D. and Stormo, G.D. (2009) Inferring binding energies from selected binding sites. PLoS Comput. Biol., 5, e1000590.
    • (2009) PLoS Comput. Biol. , vol.5
    • Zhao, Y.1    Granas, D.2    Stormo, G.D.3
  • 10
    • 68049083831 scopus 로고    scopus 로고
    • Incorporating nucleosomes into thermodynamic models of transcription regulation
    • Raveh-Sadka, T., Levo, M. and Segal, E. (2009) Incorporating nucleosomes into thermodynamic models of transcription regulation. Genome Res., 19, 1480-1496.
    • (2009) Genome Res. , vol.19 , pp. 1480-1496
    • Raveh-Sadka, T.1    Levo, M.2    Segal, E.3
  • 11
    • 70350741354 scopus 로고    scopus 로고
    • An ensemble model of competitive multi-factor binding of the genome
    • Wasson, T. and Hartemink, A.J. (2009) An ensemble model of competitive multi-factor binding of the genome. Genome Res., 19, 2101-2112.
    • (2009) Genome Res. , vol.19 , pp. 2101-2112
    • Wasson, T.1    Hartemink, A.J.2
  • 12
    • 77951800353 scopus 로고    scopus 로고
    • An effective model for natural selection in promoters
    • Hoffman, M.M. and Birney, E. (2010) An effective model for natural selection in promoters. Genome Res., 20, 685-692.
    • (2010) Genome Res. , vol.20 , pp. 685-692
    • Hoffman, M.M.1    Birney, E.2
  • 13
    • 79952273012 scopus 로고    scopus 로고
    • Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early drosophila development
    • Kaplan, T., Li, X.Y., Sabo, P.J., Thomas, S., Stamatoyannopoulos, J.A., Biggin, M.D. and Eisen, M.B. (2011) Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early drosophila development. PLoS Genet., 7, e1001290.
    • (2011) PLoS Genet. , vol.7
    • Kaplan, T.1    Li, X.Y.2    Sabo, P.J.3    Thomas, S.4    Stamatoyannopoulos, J.A.5    Biggin, M.D.6    Eisen, M.B.7
  • 15
    • 0014945567 scopus 로고
    • The lac represser-operator interaction: III Kinetic studies
    • Riggs, A.D., Bourgeois, S. and Cohn, M. (1970) The lac represser-operator interaction: III Kinetic studies. J. Mol. Biol., 53, 401-417.
    • (1970) J. Mol. Biol. , vol.53 , pp. 401-417
    • Riggs, A.D.1    Bourgeois, S.2    Cohn, M.3
  • 17
    • 33645807371 scopus 로고    scopus 로고
    • A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA
    • Blainey, P.C., van Oijen, A.M., Banerjee, A., Verdine, G.L. and Xie, X.S. (2006) A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA. Proc. Natl Acad. Sci. USA, 103, 5752-5757.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 5752-5757
    • Blainey, P.C.1    Van Oijen, A.M.2    Banerjee, A.3    Verdine, G.L.4    Xie, X.S.5
  • 18
    • 34249932435 scopus 로고    scopus 로고
    • Probing transcription factor dynamics at the single-molecule level in a living cell
    • DOI 10.1126/science.1141967
    • Elf, J., Li, G.W. and Xie, X.S. (2007) Probing transcription factor dynamics at the single-molecule level in a living cell. Science, 316, 1191-1194. (Pubitemid 46877481)
    • (2007) Science , vol.316 , Issue.5828 , pp. 1191-1194
    • Elf, J.1    Li, G.-W.2    Xie, X.S.3
  • 19
    • 84862624197 scopus 로고    scopus 로고
    • The lac repressor displays facilitated diffusion in living cells
    • Hammar, P., Leroy, P., Mahmutovic, A., Marklund, E.G., Berg, O.G. and Elf, J. (2012) The lac repressor displays facilitated diffusion in living cells. Science, 336, 1595-1598.
    • (2012) Science , vol.336 , pp. 1595-1598
    • Hammar, P.1    Leroy, P.2    Mahmutovic, A.3    Marklund, E.G.4    Berg, O.G.5    Elf, J.6
  • 20
    • 0019887628 scopus 로고
    • Diffusion-driven mechanisms of protein translocation on nucleic acids. 1. Models and theory
    • Berg, O.G., Winter, R.B. and von Hippel, P.H. (1981) Diffusion-driven mechanisms of protein translocation on nucleic acids. 1. Models and theory. Biochemistry, 20, 6929-6948.
    • (1981) Biochemistry , vol.20 , pp. 6929-6948
    • Berg, O.G.1    Winter, R.B.2    Von Hippel, P.H.3
  • 21
    • 3042579602 scopus 로고    scopus 로고
    • How do site-specific DNA-binding proteins find their targets?
    • DOI 10.1093/nar/gkh624
    • Halford, S.E. and Marko, J.F. (2004) How do site-specific DNA-binding proteins find their targets? Nucleic Acids Res., 32, 3040-3052. (Pubitemid 39022995)
    • (2004) Nucleic Acids Research , vol.32 , Issue.10 , pp. 3040-3052
    • Halford, S.E.1    Marko, J.F.2
  • 23
    • 84867364776 scopus 로고    scopus 로고
    • Computational models for large-scale simulations of facilitated diffusion
    • Zabet, N.R. and Adryan, B. (2012) Computational models for large-scale simulations of facilitated diffusion. Mol. Biosyst., 8, 2815-2827.
    • (2012) Mol. Biosyst. , vol.8 , pp. 2815-2827
    • Zabet, N.R.1    Adryan, B.2
  • 24
    • 79251584676 scopus 로고    scopus 로고
    • Physics of protein-DNA interactions: Mechanisms of facilitated target search
    • Kolomeisky, A.B. (2011) Physics of protein-DNA interactions: mechanisms of facilitated target search. Phys. Chem. Chem. Phys., 13, 2088-2095.
    • (2011) Phys. Chem. Chem. Phys. , vol.13 , pp. 2088-2095
    • Kolomeisky, A.B.1
  • 25
    • 4444236055 scopus 로고    scopus 로고
    • Kinetics of target localization of a protein on DNA: A stochastic approach
    • DOI 10.1529/biophysj.104.045773
    • Coppey, M., Benichou, O., Voituriez, R. and Moreau, M. (2004) Kinetics of target site localization of a protein on DNA: a stochastic approach. Biophys. J., 87, 1640-1649. (Pubitemid 39167021)
    • (2004) Biophysical Journal , vol.87 , Issue.3 , pp. 1640-1649
    • Coppey, M.1    Benichou, O.2    Voituriez, R.3    Moreau, M.4
  • 26
    • 10044223573 scopus 로고    scopus 로고
    • Kinetics of protein-DNA interaction: Facilitated target location in sequence-dependent potential
    • DOI 10.1529/biophysj.104.050765
    • Slutsky, M. and Mirny, L.A. (2004) Kinetics of protein-DNA interaction: facilitated target location in sequence-dependent potential. Biophys. J., 87, 4021-4035. (Pubitemid 39602906)
    • (2004) Biophysical Journal , vol.87 , Issue.6 , pp. 4021-4035
    • Slutsky, M.1    Mirny, L.A.2
  • 27
    • 23244432464 scopus 로고    scopus 로고
    • Target search of N sliding proteins on a DNA
    • DOI 10.1529/biophysj.104.057612
    • Sokolov, I.M., Metzler, R., Pant, K. and Williams, M.C. (2005) Target search of N sliding proteins on a DNA. Biophys. J., 89, 895-902. (Pubitemid 41098976)
    • (2005) Biophysical Journal , vol.89 , Issue.2 , pp. 895-902
    • Sokolov, I.M.1    Metzler, R.2    Pant, K.3    Williams, M.C.4
  • 29
    • 33645816459 scopus 로고    scopus 로고
    • How proteins search for their specific sites on DNA: The role of DNA conformation
    • Hu, T., Grosberg, A.Y. and Shklovskii, B.I. (2006) How proteins search for their specific sites on DNA: the role of DNA conformation. Biophys. J., 90, 2731-2744.
    • (2006) Biophys. J. , vol.90 , pp. 2731-2744
    • Hu, T.1    Grosberg, A.Y.2    Shklovskii, B.I.3
  • 31
    • 63849284078 scopus 로고    scopus 로고
    • Effects of macromolecular crowding and DNA looping on gene regulation kinetics
    • Li, G.W., Berg, O.G. and Elf, J. (2009) Effects of macromolecular crowding and DNA looping on gene regulation kinetics. Nat. Phys., 5, 294-297.
    • (2009) Nat. Phys. , vol.5 , pp. 294-297
    • Li, G.W.1    Berg, O.G.2    Elf, J.3
  • 34
    • 72149101003 scopus 로고    scopus 로고
    • Facilitated diffusion in a crowded environment: From kinetics to stochastics
    • Meroz, Y., Eliazar, I. and Klafter, J. (2009) Facilitated diffusion in a crowded environment: from kinetics to stochastics. J. Phys. A Math theor., 42, 434012.
    • (2009) J. Phys. A Math theor. , vol.42 , pp. 434012
    • Meroz, Y.1    Eliazar, I.2    Klafter, J.3
  • 37
    • 79957788301 scopus 로고    scopus 로고
    • Rapid search for specific sites on DNA through conformational switch of nonspecifically bound proteins
    • Zhou, H.X. (2011) Rapid search for specific sites on DNA through conformational switch of nonspecifically bound proteins. Proc. Natl Acad. Sci. USA, 108, 8651-8656.
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 8651-8656
    • Zhou, H.X.1
  • 38
    • 84860495813 scopus 로고    scopus 로고
    • GRiP: A computational tool to simulate transcription factor binding in prokaryotes
    • Zabet, N.R. and Adryan, B. (2012) GRiP: a computational tool to simulate transcription factor binding in prokaryotes. Bioinformatics, 28, 1287-1289.
    • (2012) Bioinformatics , vol.28 , pp. 1287-1289
    • Zabet, N.R.1    Adryan, B.2
  • 39
    • 84861756737 scopus 로고    scopus 로고
    • A comprehensive computational model of facilitated diffusion in prokaryotes
    • Zabet, N.R. and Adryan, B. (2012) A comprehensive computational model of facilitated diffusion in prokaryotes. Bioinformatics, 28, 1517-1524.
    • (2012) Bioinformatics , vol.28 , pp. 1517-1524
    • Zabet, N.R.1    Adryan, B.2
  • 40
    • 33845442827 scopus 로고    scopus 로고
    • Diffusion of transcription factors can drastically enhance the noise in gene expression
    • DOI 10.1529/biophysj.106.086157
    • van Zon, J.S., Morelli, M.J., Tanase-Nicola, S. and ten Wolde, P.R. (2006) Diffusion of transcription factors can drastically enhance the noise in gene expression. Biophys. J., 91, 4350-4367. (Pubitemid 44904223)
    • (2006) Biophysical Journal , vol.91 , Issue.12 , pp. 4350-4367
    • Van Zon, J.S.1    Morelli, M.J.2    Tanase-Nicola, S.3    Ten Wolde, P.R.4
  • 41
    • 84867517832 scopus 로고    scopus 로고
    • Facilitated diffusion on mobile DNA: Configurational traps and sequence heterogeneity
    • Brackley, C.A., Cates, M.E. and Marenduzzo, D. (2012) Facilitated diffusion on mobile DNA: configurational traps and sequence heterogeneity. Phys. Rev. Lett., 109, 168103.
    • (2012) Phys. Rev. Lett. , vol.109 , pp. 168103
    • Brackley, C.A.1    Cates, M.E.2    Marenduzzo, D.3
  • 43
    • 84872513867 scopus 로고    scopus 로고
    • In vivo facilitated diffusion model
    • Bauer, M. and Metzler, R. (2013) In vivo facilitated diffusion model. PLoS One, 8, e53956.
    • (2013) PLoS One , vol.8
    • Bauer, M.1    Metzler, R.2
  • 44
    • 84885406352 scopus 로고    scopus 로고
    • The effects of transcription factor competition on gene regulation
    • Zabet, N.R. and Adryan, B. (2013) The effects of transcription factor competition on gene regulation. Front. Genet., 4, 197.
    • (2013) Front. Genet. , vol.4 , pp. 197
    • Zabet, N.R.1    Adryan, B.2
  • 45
    • 15544371346 scopus 로고    scopus 로고
    • Gene regulation at the single-cell level
    • DOI 10.1126/science.1106914
    • Rosenfeld, N., Young, J.W., Alon, U., Swain, P.S. and Elowitz, M.B. (2005) Gene regulation at the single-cell level. Science, 307, 1962-1965. (Pubitemid 40404705)
    • (2005) Science , vol.307 , Issue.5717 , pp. 1962-1965
    • Rosenfeld, N.1    Young, J.W.2    Alon, U.3    Swain, P.S.4    Elowitz, M.B.5
  • 46
    • 84865819662 scopus 로고    scopus 로고
    • System size reduction in stochastic simulations of the facilitated diffusion mechanism
    • Zabet, N.R. (2012) System size reduction in stochastic simulations of the facilitated diffusion mechanism. BMC Syst. Biol., 6, 121.
    • (2012) BMC Syst. Biol. , vol.6 , pp. 121
    • Zabet, N.R.1
  • 48
    • 0017030517 scopus 로고
    • A general method for numerically simulating the stochastic time evolution of coupled chemical reactions
    • Gillespie, D.T. (1976) A general method for numerically simulating the stochastic time evolution of coupled chemical reactions. J. Comput. Phys., 22, 403-434.
    • (1976) J. Comput. Phys. , vol.22 , pp. 403-434
    • Gillespie, D.T.1
  • 49
    • 33645429016 scopus 로고
    • Exact stochastic simulation of coupled chemical reactions
    • Gillespie, D.T. (1977) Exact stochastic simulation of coupled chemical reactions. J. Phys. Chem., 81, 2340-2361.
    • (1977) J. Phys. Chem. , vol.81 , pp. 2340-2361
    • Gillespie, D.T.1
  • 50
    • 0034225547 scopus 로고    scopus 로고
    • The chemical Langevin equation
    • Gillespie, D.T. (2000) The chemical Langevin equation. J. Chem. Phys., 113, 297-306.
    • (2000) J. Chem. Phys. , vol.113 , pp. 297-306
    • Gillespie, D.T.1
  • 52
    • 84884268708 scopus 로고    scopus 로고
    • Intracellular facilitated diffusion: Searchers, crowders, and blockers
    • Brackley, C.A., Cates, M.E. and Marenduzzo, D. (2013) Intracellular facilitated diffusion: searchers, crowders, and blockers. Phys. Rev. Lett., 111, 108101.
    • (2013) Phys. Rev. Lett. , vol.111 , pp. 108101
    • Brackley, C.A.1    Cates, M.E.2    Marenduzzo, D.3
  • 53
    • 46349108554 scopus 로고    scopus 로고
    • Spatial effects on the speed and reliability of protein-DNA search
    • DOI 10.1093/nar/gkn173
    • Wunderlich, Z. and Mirny, L.A. (2008) Spatial effects on the speed and reliability of protein-DNA search. Nucleic Acids Res., 36, 3570-3578. (Pubitemid 351917521)
    • (2008) Nucleic Acids Research , vol.36 , Issue.11 , pp. 3570-3578
    • Wunderlich, Z.1    Mirny, L.A.2
  • 54
    • 0037126028 scopus 로고    scopus 로고
    • Physical constraints and functional characteristics of transcription factor-DNA interactions
    • Gerland, U., Moroz, J.D. and Hwa, T. (2002) Physical constraints and functional characteristics of transcription factor-DNA interactions. Proc. Natl Acad. Sci. USA, 99, 12015-12020.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 12015-12020
    • Gerland, U.1    Moroz, J.D.2    Hwa, T.3
  • 55
    • 0023032496 scopus 로고
    • Mapping of the sites of protection on a 5 S RNA gene by the Xenopus transcription factor IIIA. A model for the interaction
    • DOI 10.1016/0022-2836(86)90278-0
    • Fairall, L., Rhodes, D. and Klug, A. (1986) Mapping of the sites of protection on a 5 S RNA gene by the Xenopus transcription factor IIIA. A model for the interaction. J. Mol. Biol., 192, 577-591. (Pubitemid 17208453)
    • (1986) Journal of Molecular Biology , vol.192 , Issue.3 , pp. 577-591
    • Fairall, L.1    Rhodes, D.2    Klug, A.3
  • 56
    • 0026771275 scopus 로고
    • Sliding and intermolecular transfer of the lac repressor: Kinetic perturbation of a reaction intermediate by a distant DNA sequence
    • Ruusala, T. and Crothers, D.M. (1992) Sliding and intermolecular transfer of the lac repressor: kinetic perturbation of a reaction intermediate by a distant DNA sequence. Proc. Natl Acad. Sci. USA, 89, 4903-4907.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 4903-4907
    • Ruusala, T.1    Crothers, D.M.2
  • 59
    • 0002643986 scopus 로고
    • The dip test of unimodality
    • Hartigan, J.A. and Hartigan, P.M. (1985) The dip test of unimodality. Ann. Stat., 13, 70-84.
    • (1985) Ann. Stat. , vol.13 , pp. 70-84
    • Hartigan, J.A.1    Hartigan, P.M.2
  • 63
    • 84863404645 scopus 로고    scopus 로고
    • Evolutionary origins of transcription factor binding site clusters
    • He, X., Duque, T.S. and Sinha, S. (2012) Evolutionary origins of transcription factor binding site clusters. Mol. Biol. Evol., 29, 1059-1070.
    • (2012) Mol. Biol. Evol. , vol.29 , pp. 1059-1070
    • He, X.1    Duque, T.S.2    Sinha, S.3
  • 64
    • 76749088015 scopus 로고    scopus 로고
    • Evolutionary mirages: Selection on binding site composition creates the illusion of conserved grammars in Drosophila enhancers
    • Lusk, R.W. and Eisen, M.B. (2010) Evolutionary mirages: selection on binding site composition creates the illusion of conserved grammars in Drosophila enhancers. PLoS Genet., 6, e1000829.
    • (2010) PLoS Genet. , vol.6
    • Lusk, R.W.1    Eisen, M.B.2
  • 65
    • 80055083209 scopus 로고    scopus 로고
    • Formation of regulatory modules by local sequence duplication
    • Nourmohammad, A. and Lassig, M. (2011) Formation of regulatory modules by local sequence duplication. PLoS Comput. Biol., 7, e1002167.
    • (2011) PLoS Comput. Biol. , vol.7
    • Nourmohammad, A.1    Lassig, M.2
  • 66
    • 33846165487 scopus 로고    scopus 로고
    • Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation
    • DOI 10.1038/nbt1270, PII NBT1270
    • Lu, P., Vogel, C., Wang, R., Yao, X. and Marcotte, E.M. (2007) Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation. Nat. Biotechnol., 25, 117-124. (Pubitemid 46087910)
    • (2007) Nature Biotechnology , vol.25 , Issue.1 , pp. 117-124
    • Lu, P.1    Vogel, C.2    Wang, R.3    Yao, X.4    Marcotte, E.M.5
  • 67
    • 36249017917 scopus 로고    scopus 로고
    • Programming gene expression with combinatorial promoters
    • CoxIII, R.S., Surette, M.G. and Elowitz, M.B. (2007) Programming gene expression with combinatorial promoters. Mol. Syst. Biol., 3, 145.
    • (2007) Mol. Syst. Biol. , vol.3 , pp. 145
    • Cox III, R.S.1    Surette, M.G.2    Elowitz, M.B.3
  • 70
    • 57349140010 scopus 로고    scopus 로고
    • Transcriptional regulation constrains the organization of genes on eukaryotic chromosomes
    • Janga, S.C., Collado-Vides, J. and Babu, M.M. (2008) Transcriptional regulation constrains the organization of genes on eukaryotic chromosomes. Proc. Natl Acad. Sci. USA, 105, 15761-15766.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 15761-15766
    • Janga, S.C.1    Collado-Vides, J.2    Babu, M.M.3
  • 71
    • 0036578795 scopus 로고    scopus 로고
    • Network motifs in the transcriptional regulation network of Escherichia coli
    • Shen-Orr, S.S., Milo, R., Mangan, S. and Alon, U. (2002) Network motifs in the transcriptional regulation network of Escherichia coli. Nat. Genet., 31, 64-68.
    • (2002) Nat. Genet. , vol.31 , pp. 64-68
    • Shen-Orr, S.S.1    Milo, R.2    Mangan, S.3    Alon, U.4
  • 72
    • 77953170555 scopus 로고    scopus 로고
    • Computational limits to binary genes
    • Zabet, N.R. and Chu, D.F. (2010) Computational limits to binary genes. J. R. Soc. Interface, 7, 945-954.
    • (2010) J. R. Soc. Interface , vol.7 , pp. 945-954
    • Zabet, N.R.1    Chu, D.F.2
  • 73
    • 77949524141 scopus 로고    scopus 로고
    • A biophysical model for analysis of transcription factor interaction and binding site arrangement from genome-wide binding data
    • He, X., Chen, C.C., Hong, F., Fang, F., Sinha, S., Ng, H.H. and Zhong, S. (2009) A biophysical model for analysis of transcription factor interaction and binding site arrangement from genome-wide binding data. PLoS One, 4, e8155.
    • (2009) PLoS One , vol.4
    • He, X.1    Chen, C.C.2    Hong, F.3    Fang, F.4    Sinha, S.5    Ng, H.H.6    Zhong, S.7


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