Nanoparticles with surface antibody against CD98 and carrying CD98 small interfering RNA reduce colitis in mice

Gastroenterology

Volumn 146, Issue 5, 2014, Pages

  Xiao, Bo ^a   Laroui, Hamed ^a   Viennois, Emilie ^a,b   Ayyadurai, Saravanan ^a   Charania, Moiz A ^a   Zhang, Yuchen ^a   Zhang, Zhan ^a   Baker, Mark T ^a   Zhang, Benyue ^a   Gewirtz, Andrew T ^a,c   Merlin, Didier ^a,b  

^a GEORGIA STATE UNIVERSITY   (United States)

^b ATLANTA VA MEDICAL CENTER   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CD98; Colitis Targeted Therapy; Gene Silencing; Keywords; Mouse Model

Indexed keywords

ALGINIC ACID; ANTIBODY; CD45RB ANTIGEN; CD98 ANTIBODY; CD98 ANTIGEN; CHITOSAN; DEXTRAN SULFATE; DRUG CARRIER; INTERLEUKIN 12; INTERLEUKIN 6; MYELOPEROXIDASE; NANOPARTICLE; POLYETHYLENEIMINE; PROTEIN KINASE C; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC FORCE MICROSCOPY; BIOCOMPATIBILITY; BODY WEIGHT; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CELL VIABILITY; COACERVATION; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; CYTOTOXICITY; DISEASE SEVERITY; DOWN REGULATION; DYNAMIC LIGHT SCATTERING; ENZYME ACTIVITY; FEEDING; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE OVEREXPRESSION; GOBLET CELL; HISTOLOGY; HYDROGEL; IMPEDANCE; INTESTINE CELL; INTESTINE EPITHELIUM CELL; LIGHT SCATTERING; LYSOSOME; MACROPHAGE; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURFACE PLASMON RESONANCE; ZETA POTENTIAL;

CD98; COLITIS-TARGETED THERAPY; GENE SILENCING; MOUSE MODEL;

ADMINISTRATION, ORAL; ALGINATES; ANIMALS; ANTIGENS, CD98; CELL LINE; CHITOSAN; COLITIS; COLON; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; GENETIC THERAPY; GLUCURONIC ACID; HEXURONIC ACIDS; HOMEODOMAIN PROTEINS; HYDROGELS; INTERLEUKIN-12; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NANOMEDICINE; NANOPARTICLES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SEVERITY OF ILLNESS INDEX; SINGLE-CHAIN ANTIBODIES; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84898992120     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2014.01.056     Document Type: Article

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