Acquisition of antigen-presenting functions by neutrophils isolated from mice with chronic colitis

Journal of Immunology

Volumn 188, Issue 3, 2012, Pages 1491-1502

  Ostanin, Dmitry V ^a,b   Kurmaeva, Elvira ^b   Furr, Katie ^a   Bao, Richard ^b   Hoffman, Jason ^a   Berney, Seth ^b   Grisham, Matthew B ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b Louisiana State University School of Medicine Shreveport   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CD103 ANTIGEN; CD11B ANTIGEN; CD45RB ANTIGEN; CD8 ANTIGEN; CD86 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 17; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CELL INFILTRATION; CELL ISOLATION; CELL PROLIFERATION; CHRONIC DISEASE; COCULTURE; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EOSINOPHIL; GRANULOCYTE; HISTOPATHOLOGY; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MESENTERY LYMPH NODE; MONOCYTE; MOUSE; MYELOPOIESIS; NEUTROPHIL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGEN PRESENTATION; CELL PROLIFERATION; CHRONIC DISEASE; COLITIS; INFLAMMATION MEDIATORS; LYMPHOCYTE ACTIVATION; MICE; NEUTROPHILS; T-LYMPHOCYTES;

EID: 84856566896     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102296     Document Type: Article

References (88)

1. Korzenik, J. R., and D. K. Podolsky. 2006. Evolving knowledge and therapy of inflammatory bowel disease. Nat. Rev. Drug Discov. 5: 197-209. (Pubitemid 43336033)
2. Le Berre, N., D. Heresbach, M. Kerbaol, S. Caulet, J. F. Bretagne, J. Chaperon, M. Gosselin, and M. P. Ramée. 1995. Histological discrimination of idiopathic inflammatory bowel disease from other types of colitis. J. Clin. Pathol. 48: 749-753.
3. Podolsky, D. K. 2002. Inflammatory bowel disease. N. Engl. J. Med. 347: 417-429. (Pubitemid 34851835)
4. Haile, L. A., R. von Wasielewski, J. Gamrekelashvili, C. Kruger, O. Bachmann, A. M. Westendorf, J. Buer, R. Liblau, M. P. Manns, F. Korangy, et al. 2008. Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway. Gastroenterology 135: 871-881.
5. Kühl, A. A., H. Kakirman, M. Janotta, S. Dreher, P. Cremer, N. N. Pawlowski, C. Loddenkemper, M. M. Heimesaat, K. Grollich, M. Zeitz, et al. 2007. Aggravation of different types of experimental colitis by depletion or adhesion blockade of neutrophils. Gastroenterology 133: 1882-1892. (Pubitemid 350180801)
6. + T cells by increased granulopoiesis. Inflamm. Bowel Dis. 14: 1491-1503.
7. + population in spleen of dextran sulfate sodium administered mice works to repair colitis. Inflamm. Allergy Drug Targets 10: 39-46.
8. Foell, D., T. Kucharzik, M. Kraft, T. Vogl, C. Sorg, W. Domschke, and J. Roth. 2003. Neutrophil derived human S100A12 (EN-RAGE) is strongly expressed during chronic active inflammatory bowel disease. Gut 52: 847-853. (Pubitemid 36613492)
9. Chin, A. C., and C. A. Parkos. 2007. Pathobiology of neutrophil transepithelial migration: implications in mediating epithelial injury. Annu. Rev. Pathol. 2: 111-143. (Pubitemid 46448062)
10. Chin, A. C., and C. A. Parkos. 2006. Neutrophil transepithelial migration and epithelial barrier function in IBD: potential targets for inhibiting neutrophil trafficking. Ann. N. Y. Acad. Sci. 1072: 276-287. (Pubitemid 44448460)
11. Natsui, M., K. Kawasaki, H. Takizawa, S. I. Hayashi, Y. Matsuda, K. Sugimura, K. Seki, R. Narisawa, F. Sendo, and H. Asakura. 1997. Selective depletion of neutrophils by a monoclonal antibody, RP-3, suppresses dextran sulphate sodium-induced colitis in rats. J. Gastroenterol. Hepatol. 12: 801-808. (Pubitemid 28088064)
12. Qualls, J. E., A. M. Kaplan, N. van Rooijen, and D. A. Cohen. 2006. Suppression of experimental colitis by intestinal mononuclear phagocytes. J. Leukoc. Biol. 80: 802-815. (Pubitemid 44835899)
13. Buell, M. G., and M. C. Berin. 1994. Neutrophil-independence of the initiation of colonic injury. Comparison of results from three models of experimental colitis in the rat. Dig. Dis. Sci. 39: 2575-2588.
14. Yamada, T., B. J. Zimmerman, R. D. Specian, and M. B. Grisham. 1991. Role of neutrophils in acetic acid-induced colitis in rats. Inflammation 15: 399-411.
15. Liu, Z. X., D. Han, B. Gunawan, and N. Kaplowitz. 2006. Neutrophil depletion protects against murine acetaminophen hepatotoxicity. Hepatology 43: 1220-1230. (Pubitemid 43980100)
16. Abbitt, K. B., M. J. Cotter, V. C. Ridger, D. C. Crossman, P. G. Hellewell, and K. E. Norman. 2009. Antibody ligation of murine Ly-6G induces neutropenia, blood flow cessation, and death via complement-dependent and independent mechanisms. J. Leukoc. Biol. 85: 55-63.
17. Norman, K. E., M. J. Cotter, J. B. Stewart, K. B. Abbitt, M. Ali, B. E. Wagner, W. A. Wallace, S. B. Forlow, and P. G. Hellewell. 2003. Combined anticoagulant and antiselectin treatments prevent lethal intravascular coagulation. Blood 101: 921-928. (Pubitemid 36139360)
18. Ribechini, E., P. J. Leenen, and M. B. Lutz. 2009. Gr-1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid-derived suppressor cell activity in BM cells. Eur. J. Immunol. 39: 3538-3551.
19. hi suppressive monocytes in experimental autoimmune encephalomyelitis. J. Immunol. 179: 5228-5237.
20. Daley, J. M., A. A. Thomay, M. D. Connolly, J. S. Reichner, and J. E. Albina. 2008. Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice. J. Leukoc. Biol. 83: 64-70.
21. Ostanin, D. V., J. Bao, I. Koboziev, L. Gray, S. A. Robinson-Jackson, M. Kosloski-Davidson, V. H. Price, and M. B. Grisham. 2009. T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade. Am. J. Physiol. Gastrointest. Liver Physiol. 296: G135-G146.
22. Ostanin, D. V., K. P. Pavlick, S. Bharwani, D. D'Souza, K. L. Furr, C. M. Brown, and M. B. Grisham. 2006. T cell-induced inflammation of the small and large intestine in immunodeficient mice. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G109-G119.
23. Pavlick, K. P., D. V. Ostanin, K. L. Furr, F. S. Laroux, C. M. Brown, L. Gray, C. G. Kevil, and M. B. Grisham. 2006. Role of T-cell-associated lymphocyte function-associated antigen-1 in the pathogenesis of experimental colitis. Int. Immunol. 18: 389-398. (Pubitemid 43160151)
24. Arndt, H., P. Kubes, M. B. Grisham, E. Gonzalez, and D. N. Granger. 1992. Granulocyte turnover in the feline intestine. Inflammation 16: 549-559.
25. Krawisz, J. E., P. Sharon, and W. F. Stenson. 1984. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity: assessment of inflammation in rat and hamster models. Gastroenterology 87: 1344-1350. (Pubitemid 15201434)
26. Laroux, F. S., H. H. Norris, J. Houghton, K. P. Pavlick, S. Bharwani, D. M. Merrill, J. Fuseler, R. Chervenak, and M. B. Grisham. 2004. Regulation of chronic colitis in athymic nu/nu (nude) mice. Int. Immunol. 16: 77-89. (Pubitemid 38054629)
27. Germain, R. N., A. Bhattacharya, M. E. Dorf, and T. A. Springer. 1982. A single monoclonal anti-Ia antibody inhibits antigen-specific T cell proliferation controlled by distinct Ir genes mapping in different H-2 I subregions. J. Immunol. 128: 1409-1413. (Pubitemid 12188475)
28. + T cells from scid mice with inflammatory bowel disease. Eur. J. Immunol. 31: 23-31.
29. LeibundGut-Landmann, S., J. M. Waldburger, C. Reis e Sousa, H. Acha-Orbea, and W. Reith. 2004. MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells. Nat. Immunol. 5: 899-908.
30. Lefever, S., J. Vandesompele, F. Speleman, and F. Pattyn. 2009. RTPrimerDB: the portal for real-time PCR primers and probes. Nucleic Acids Res. 37(Database issue): D942-D945.
31. Rasband, W. S. 2011. ImageJ. U.S. National Institutes of Health, Bethesda, MD.
32. Delano, M. J., P. O. Scumpia, J. S. Weinstein, D. Coco, S. Nagaraj, K. M. Kelly-Scumpia, K. A. O'Malley, J. L. Wynn, S. Antonenko, S. Z. Al-Quran, et al. 2007. MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J. Exp. Med. 204: 1463-1474. (Pubitemid 46919883)
33. Biermann, H., B. Pietz, R. Dreier, K. W. Schmid, C. Sorg, and C. Sunderkötter. 1999. Murine leukocytes with ring-shaped nuclei include granulocytes, monocytes, and their precursors. J. Leukoc. Biol. 65: 217-231. (Pubitemid 29077015)
34. Bainton, D. F. 1992. Developmental biology of neutrophils and eosinophils. In Inflammation: Basic Principles and Clinical Correlates, 2nd Ed., J. I. Gallin, I. M. Goldstein, and R. Snyderman, eds. Raven Press, New York, p. 303-324.
35. Lagasse, E., and I. L. Weissman. 1996. Flow cytometric identification of murine neutrophils and monocytes. J. Immunol. Methods 197: 139-150. (Pubitemid 26342018)
36. Fleming, T. J., M. L. Fleming, and T. R. Malek. 1993. Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow: RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. J. Immunol. 151: 2399-2408. (Pubitemid 23264492)
37. Goldrath, A. W., L. Y. Bogatzki, and M. J. Bevan. 2000. Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J. Exp. Med. 192: 557-564. (Pubitemid 30666256)
38. Rydström, A., and M. J. Wick. 2007. Monocyte recruitment, activation, and function in the gut-associated lymphoid tissue during oral Salmonella infection. J. Immunol. 178: 5789-5801. (Pubitemid 46674376)
39. Nikolic, T., G. Bouma, H. A. Drexhage, and P. J. Leenen. 2005. Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro. J. Leukoc. Biol. 78: 70-79. (Pubitemid 40979945)
40. Nikolic, T., S. B. Geutskens, N. van Rooijen, H. A. Drexhage, and P. J. Leenen. 2005. Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri)-insulitis of the nonobese diabetic mouse: a phagocyte depletion study. Lab. Invest. 85: 487-501. (Pubitemid 40523941)
41. Sunderkötter, C., T. Nikolic, M. J. Dillon, N. Van Rooijen, M. Stehling, D. A. Drevets, and P. J. Leenen. 2004. Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J. Immunol. 172: 4410-4417. (Pubitemid 38375256)
42. Arnold, L., A. Henry, F. Poron, Y. Baba-Amer, N. van Rooijen, A. Plonquet, R. K. Gherardi, and B. Chazaud. 2007. Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. J. Exp. Med. 204: 1057-1069. (Pubitemid 46798150)
43. McGarry, M. P., and C. C. Stewart. 1991. Murine eosinophil granulocytes bind the murine macrophage-monocyte specific monoclonal antibody F4/80. J. Leukoc. Biol. 50: 471-478.
44. Austyn, J. M., and S. Gordon. 1981. F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol. 11: 805-815. (Pubitemid 12237981)
45. Ezekowitz, R. A., and S. Gordon. 1982. Down-regulation of mannosyl receptor-mediated endocytosis and antigen F4/80 in bacillus Calmette- Guérin-activated mouse macrophages: role of T lymphocytes and lymphokines. J. Exp. Med. 155: 1623-1637. (Pubitemid 12074203)
46. Nahrendorf, M., F. K. Swirski, E. Aikawa, L. Stangenberg, T. Wurdinger, J. L. Figueiredo, P. Libby, R. Weissleder, and M. J. Pittet. 2007. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J. Exp. Med. 204: 3037-3047. (Pubitemid 350179569)
47. Iking-Konert, C., S. Vogt, M. Radsak, C. Wagner, G. M. Hänsch, and K. Andrassy. 2001. Polymorphonuclear neutrophils inWegener's granulomatosis acquire characteristics of antigen presenting cells. Kidney Int. 60: 2247-2262. (Pubitemid 33070467)
48. Iking-Konert, C., B. Ostendorf, O. Sander, M. Jost, C. Wagner, L. Joosten, M. Schneider, and G. M. Hänsch. 2005. Transdifferentiation of polymorphonuclear neutrophils to dendritic-like cells at the site of inflammation in rheumatoid arthritis: evidence for activation by T cells. Ann. Rheum. Dis. 64: 1436-1442. (Pubitemid 41623854)
49. Wagner, C., C. Iking-Konert, F. Hug, S. Stegmaier, V. Heppert, A. Wentzensen, and G. M. Hänsch. 2006. Cellular inflammatory response to persistent localized Staphylococcus aureus infection: phenotypical and functional characterization of polymorphonuclear neutrophils (PMN). Clin. Exp. Immunol. 143: 70-77.
50. Gosselin, E. J., K. Wardwell, W. F. Rigby, and P. M. Guyre. 1993. Induction of MHC class II on human polymorphonuclear neutrophils by granulocyte/macrophage colony-stimulating factor, IFN-γ, and IL-3. J. Immunol. 151: 1482-1490. (Pubitemid 23219286)
51. Oehler, L., O. Majdic, W. F. Pickl, J. Stöckl, E. Riedl, J. Drach, K. Rappersberger, K. Geissler, and W. Knapp. 1998. Neutrophil granulocyte-committed cells can be driven to acquire dendritic cell characteristics. J. Exp. Med. 187: 1019-1028. (Pubitemid 28176402)
52. Radsak, M., C. Iking-Konert, S. Stegmaier, K. Andrassy, and G. M. Hänsch. 2000. Polymorphonuclear neutrophils as accessory cells for T-cell activation: major histocompatibility complex class II restricted antigen-dependent induction of T-cell proliferation. Immunology 101: 521-530. (Pubitemid 32001467)
53. Sandilands, G. P., J. McCrae, K. Hill, M. Perry, and D. Baxter. 2006. Major histocompatibility complex class II (DR) antigen and costimulatory molecules on in vitro and in vivo activated human polymorphonuclear neutrophils. Immunology 119: 562-571. (Pubitemid 44722219)
54. Klebanoff, S. J., S. Olszowski, W. C. Van Voorhis, J. A. Ledbetter, A. M. Waltersdorph, and K. G. Schlechte. 1992. Effects of gamma-interferon on human neutrophils: protection from deterioration on storage. Blood 80: 225-234.
55. Lee, A., M. K. Whyte, and C. Haslett. 1993. Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators. J. Leukoc. Biol. 54: 283-288. (Pubitemid 23317694)
56. Brach, M. A., S. deVos, H. J. Gruss, and F. Herrmann. 1992. Prolongation of survival of human polymorphonuclear neutrophils by granulocyte-macrophage colony-stimulating factor is caused by inhibition of programmed cell death. Blood 80: 2920-2924.
57. Cockrell, A., F. S. Laroux, D. Jourd'heuil, S. Kawachi, L. Gray, H. Van der Heyde, and M. B. Grisham. 1999. Role of inducible nitric oxide synthase in leukocyte extravasation in vivo. Biochem. Biophys. Res. Commun. 257: 684-686. (Pubitemid 29301503)
58. Whale, T. A., T. K. Beskorwayne, L. A. Babiuk, and P. J. Griebel. 2006. Bovine polymorphonuclear cells passively acquire membrane lipids and integral membrane proteins from apoptotic and necrotic cells. J. Leukoc. Biol. 79: 1226-1233. (Pubitemid 44835556)
59. Kelsall, B. L., and F. Leon. 2005. Involvement of intestinal dendritic cells in oral tolerance, immunity to pathogens, and inflammatory bowel disease. Immunol. Rev. 206: 132-148. (Pubitemid 41105167)
60. Springer, T. A. 1990. Adhesion receptors of the immune system. Nature 346: 425-434.
61. Scholer, A., S. Hugues, A. Boissonnas, L. Fetler, and S. Amigorena. 2008. Intercellular adhesion molecule-1-dependent stable interactions between T cells and dendritic cells determine CD8+ T cell memory. Immunity 28: 258-270. (Pubitemid 351222655)
62. Ina, K., K. Kusugami, T. Hosokawa, A. Imada, T. Shimizu, T. Yamaguchi, M. Ohsuga, K. Kyokane, T. Sakai, Y. Nishio, et al. 1999. Increased mucosal production of granulocyte colony-stimulating factor is related to a delay in neutrophil apoptosis in inflammatory bowel disease. J. Gastroenterol. Hepatol. 14: 46-53. (Pubitemid 29087317)
63. Ina, K., K. Kusugami, T. Yamaguchi, A. Imada, T. Hosokawa, M. Ohsuga, M. Shinoda, T. Ando, K. Ito, and Y. Yokoyama. 1997. Mucosal interleukin-8 is involved in neutrophil migration and binding to extracellular matrix in inflammatory bowel disease. Am. J. Gastroenterol. 92: 1342-1346. (Pubitemid 27328597)
64. Noguchi, M., N. Hiwatashi, Z. X. Liu, and T. Toyota. 2001. Increased secretion of granulocyte-macrophage colony-stimulating factor in mucosal lesions of inflammatory bowel disease. Digestion 63(Suppl. 1): 32-36. (Pubitemid 32098438)
65. Abreu, M. T., S. Plevy, B. E. Sands, and R. Weinstein. 2007. Selective leukocyte apheresis for the treatment of inflammatory bowel disease. J. Clin. Gastroenterol. 41: 874-888. (Pubitemid 350307073)
66. Dougherty, G. J., S. Murdoch, and N. Hogg. 1988. The function of human intercellular adhesion molecule-1 (ICAM-1) in the generation of an immune response. Eur. J. Immunol. 18: 35-39. (Pubitemid 18072694)
67. Kanai, T., T. Hibi, and M. Watanabe. 2006. The logics of leukocytapheresis as a natural biological therapy for inflammatory bowel disease. Expert Opin. Biol. Ther. 6: 453-466. (Pubitemid 43723295)
68. Saniabadi, A. R., H. Hanai, K. Fukunaga, K. Sawada, C. Shima, I. Bjarnason, and R. Lofberg. 2007. Therapeutic leukocytapheresis for inflammatory bowel disease. Transfus. Apheresis Sci. 37: 191-200. (Pubitemid 350186259)
69. Williams, I. R., and C. A. Parkos. 2007. Colonic neutrophils in inflammatory bowel disease: double-edged swords of the innate immune system with protective and destructive capacity. Gastroenterology 133: 2049-2052. (Pubitemid 350180828)
70. Monteiro, J. P., A. Benjamin, E. S. Costa, M. A. Barcinski, and A. Bonomo. 2005. Normal hematopoiesis is maintained by activated bone marrow CD4+T cells. Blood 105: 1484-1491. (Pubitemid 40223664)
71. Swirski, F. K., M. Nahrendorf, M. Etzrodt, M. Wildgruber, V. Cortez-Retamozo, P. Panizzi, J. L. Figueiredo, R. H. Kohler, A. Chudnovskiy, P. Waterman, et al. 2009. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 325: 612-616.
72. Takebayashi, K., I. Koboziev, D. V. Ostanin, L. Gray, F. Karlsson, S. A. Robinson-Jackson, M. Kosloski-Davidson, A. B. Dooley, S. Zhang, and M. B. Grisham. 2011. Role of the gut-associated and secondary lymphoid tissue in the induction of chronic colitis. Inflamm. Bowel Dis. 17: 268-278.
73. + regulatory T cells is a suppressive site of intestinal inflammation. J. Immunol. 178: 4937-4946.
74. Liu, Z. X., N. Hiwatashi, M. Noguchi, and T. Toyota. 1997. Increased expression of costimulatory molecules on peripheral blood monocytes in patients with Crohn's disease. Scand. J. Gastroenterol. 32: 1241-1246. (Pubitemid 28023129)
75. + T cells. J. Leukoc. Biol. 88: 1163-1170.
76. Andina, N., S. Conus, E. M. Schneider, M. F. Fey, and H. U. Simon. 2009. Induction of Bim limits cytokine-mediated prolonged survival of neutrophils. Cell Death Differ. 16: 1248-1255.
77. Duffin, R., A. E. Leitch, S. Fox, C. Haslett, and A. G. Rossi. 2010. Targeting granulocyte apoptosis: mechanisms, models, and therapies. Immunol. Rev. 236: 28-40.
78. Bachmann, M. F., K. McKall-Faienza, R. Schmits, D. Bouchard, J. Beach, D. E. Speiser, T. W. Mak, and P. S. Ohashi. 1997. Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation. Immunity 7: 549-557. (Pubitemid 27508706)
79. Perez, O. D., D. Mitchell, G. C. Jager, S. South, C. Murriel, J. McBride, L. A. Herzenberg, S. Kinoshita, and G. P. Nolan. 2003. Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1. Nat. Immunol. 4: 1083-1092. (Pubitemid 37428036)
80. Grakoui, A., S. K. Bromley, C. Sumen, M. M. Davis, A. S. Shaw, P. M. Allen, and M. L. Dustin. 1999. The immunological synapse: a molecular machine controlling T cell activation. Science 285: 221-227. (Pubitemid 29329988)
81. Basu, S., G. Hodgson, H. H. Zhang, M. Katz, C. Quilici, and A. R. Dunn. 2000. "Emergency" granulopoiesis in G-CSF-deficient mice in response to Candida albicans infection. Blood 95: 3725-3733. (Pubitemid 30412843)
82. Basu, S., C. Quilici, H. H. Zhang, D. Grail, and A. R. Dunn. 2008. Mice lacking both G-CSF and IL-6 are more susceptible to Candida albicans infection: critical role of neutrophils in defense against Candida albicans. Growth Factors 26: 23-34. (Pubitemid 351448011)
83. Lieschke, G. J., D. Grail, G. Hodgson, D. Metcalf, E. Stanley, C. Cheers, K. J. Fowler, S. Basu, Y. F. Zhan, and A. R. Dunn. 1994. Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization. Blood 84: 1737-1746. (Pubitemid 24286121)
84. Walker, F., H. H. Zhang, V. Matthews, J. Weinstock, E. C. Nice, M. Ernst, S. Rose-John, and A. W. Burgess. 2008. IL6/sIL6R complex contributes to emergency granulopoietic responses in G-CSF- and GM-CSF-deficient mice. Blood 111: 3978-3985.
85. von Andrian, U. H., J. D. Chambers, E. L. Berg, S. A. Michie, D. A. Brown, D. Karolak, L. Ramezani, E. M. Berger, K. E. Arfors, and E. C. Butcher. 1993. L-selectin mediates neutrophil rolling in inflamed venules through sialyl LewisX-dependent and -independent recognition pathways. Blood 82: 182-191. (Pubitemid 23188763)
86. Haile, L. A., J. Gamrekelashvili, M. P. Manns, F. Korangy, and T. F. Greten. 2010. CD49d is a new marker for distinct myeloid-derived suppressor cell subpopulations in mice. J. Immunol. 185: 203-210.
87. Hanai, H., Y. Takeda, M. Eberhardson, R. Gruber, A. R. Saniabadi, O. Winqvist, and R. Lofberg. 2011. The mode of actions of the Adacolumn therapeutic leucocytapheresis in patients with inflammatory bowel disease: a concise review. Clin. Exp. Immunol. 163: 50-58.
88. Sands, B. E., W. J. Sandborn, B. Feagan, R. Löfberg, T. Hibi, T. Wang, L. M. Gustofson, C. J. Wong, M. K. Vandervoort, S. Hanauer, et al. 2008. A randomized, double-blind, sham-controlled study of granulocyte/monocyte apheresis for active ulcerative colitis. Gastroenterology 135: 400-409.