-
1
-
-
20244387299
-
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
-
Adolfsson J, Mansson R, Buza-Vidas N, et al. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell. 2005 ; 121: 295-306
-
(2005)
Cell
, vol.121
, pp. 295-306
-
-
Adolfsson, J.1
Mansson, R.2
Buza-Vidas, N.3
-
2
-
-
0034624828
-
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
-
Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature. 2000 ; 404: 193-197
-
(2000)
Nature
, vol.404
, pp. 193-197
-
-
Akashi, K.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
-
3
-
-
0037244284
-
Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation
-
Hock H, Hamblen MJ, Rooke HM, et al. Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation. Immunity. 2003 ; 18: 109-120
-
(2003)
Immunity
, vol.18
, pp. 109-120
-
-
Hock, H.1
Hamblen, M.J.2
Rooke, H.M.3
-
4
-
-
33747196725
-
Multilineage transcriptional priming and determination of alternate hematopoietic cell fates
-
Laslo P, Spooner CJ, Warmflash A, et al. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell. 2006 ; 126: 755-766
-
(2006)
Cell
, vol.126
, pp. 755-766
-
-
Laslo, P.1
Spooner, C.J.2
Warmflash, A.3
-
5
-
-
50849139175
-
Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system
-
Laslo P, Pongubala JM, Lancki DW, Singh H. Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system. Semin Immunol. 2008 ; 20: 228-235
-
(2008)
Semin Immunol
, vol.20
, pp. 228-235
-
-
Laslo, P.1
Pongubala, J.M.2
Lancki, D.W.3
Singh, H.4
-
6
-
-
79958032037
-
Hematopoietic cytokine-induced transcriptional regulation and Notch signaling as modulators of MDSC expansion
-
Saleem SJ, Conrad DH. Hematopoietic cytokine-induced transcriptional regulation and Notch signaling as modulators of MDSC expansion. Int Immunopharmacol. 2011 ; 11: 808-815
-
(2011)
Int Immunopharmacol
, vol.11
, pp. 808-815
-
-
Saleem, S.J.1
Conrad, D.H.2
-
7
-
-
22144447520
-
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype
-
Growney JD, Shigematsu H, Li Z, et al. Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype. Blood. 2005 ; 106: 494-504
-
(2005)
Blood
, vol.106
, pp. 494-504
-
-
Growney, J.D.1
Shigematsu, H.2
Li, Z.3
-
8
-
-
77949518018
-
MicroRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia
-
Han YC, Park CY, Bhagat G, et al. microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. J Exp Med. 2010 ; 207: 475-489
-
(2010)
J Exp Med
, vol.207
, pp. 475-489
-
-
Han, Y.C.1
Park, C.Y.2
Bhagat, G.3
-
9
-
-
0037315894
-
Disruption of differentiation in human cancer: AML shows the way
-
Tenen DG. Disruption of differentiation in human cancer: AML shows the way. Nat Rev Cancer. 2003 ; 3: 89-101
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 89-101
-
-
Tenen, D.G.1
-
10
-
-
55749099505
-
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations
-
Li Z, Lu J, Sun M, et al. Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proc Natl Acad Sci USA. 2008 ; 105: 15535-15540
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15535-15540
-
-
Li, Z.1
Lu, J.2
Sun, M.3
-
11
-
-
34347383305
-
MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation
-
Fontana L, Pelosi E, Greco P, et al. MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation. Nat Cell Biol. 2007 ; 9: 775-787
-
(2007)
Nat Cell Biol
, vol.9
, pp. 775-787
-
-
Fontana, L.1
Pelosi, E.2
Greco, P.3
-
12
-
-
39849096995
-
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
-
Johnnidis JB, Harris MH, Wheeler RT, et al. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature. 2008 ; 451: 1125-1129
-
(2008)
Nature
, vol.451
, pp. 1125-1129
-
-
Johnnidis, J.B.1
Harris, M.H.2
Wheeler, R.T.3
-
13
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol. 2009 ; 9: 162-174
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
14
-
-
65249138393
-
Myeloid-derived suppressor cells: Linking inflammation and cancer
-
Ostrand-Rosenberg S, Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol. 2009 ; 182: 4499-4506
-
(2009)
J Immunol
, vol.182
, pp. 4499-4506
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
-
15
-
-
0035164478
-
Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer
-
Almand B, Clark JI, Nikitina E, et al. Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol. 2001 ; 166: 678-689
-
(2001)
J Immunol
, vol.166
, pp. 678-689
-
-
Almand, B.1
Clark, J.I.2
Nikitina, E.3
-
16
-
-
0023136055
-
Hematopoiesis and suppressor bone marrow cells in mice bearing large metastatic Lewis lung carcinoma tumors
-
Young MR, Newby M, Wepsic HT. Hematopoiesis and suppressor bone marrow cells in mice bearing large metastatic Lewis lung carcinoma tumors. Cancer Res. 1987 ; 47: 100-105
-
(1987)
Cancer Res
, vol.47
, pp. 100-105
-
-
Young, M.R.1
Newby, M.2
Wepsic, H.T.3
-
17
-
-
0021244805
-
Influence of mammary tumor progression on phenotype and function of spleen and in situ lymphocytes in mice
-
Buessow SC, Paul RD, Lopez DM. Influence of mammary tumor progression on phenotype and function of spleen and in situ lymphocytes in mice. J Natl Cancer Inst. 1984 ; 73: 249-255
-
(1984)
J Natl Cancer Inst
, vol.73
, pp. 249-255
-
-
Buessow, S.C.1
Paul, R.D.2
Lopez, D.M.3
-
18
-
-
0021558066
-
Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: Exploring obscure relationships
-
Strober S. Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: exploring obscure relationships. Annu Rev Immunol. 1984 ; 2: 219-237
-
(1984)
Annu Rev Immunol
, vol.2
, pp. 219-237
-
-
Strober, S.1
-
19
-
-
79952822608
-
A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma
-
Cuenca AG, Delano MJ, Kelly-Scumpia KM, et al. A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma. Mol Med. 2011 ; 17: 281-292
-
(2011)
Mol Med
, vol.17
, pp. 281-292
-
-
Cuenca, A.G.1
Delano, M.J.2
Kelly-Scumpia, K.M.3
-
20
-
-
85047689277
-
Myeloid-derived suppressor cells evolve during sepsis and can enhance or attenuate the systemic inflammatory response
-
Brudecki L, Ferguson DA, McCall CE, El Gazzar M. Myeloid-derived suppressor cells evolve during sepsis and can enhance or attenuate the systemic inflammatory response. Infect Immun. 2012 ; 80: 2026-2034
-
(2012)
Infect Immun
, vol.80
, pp. 2026-2034
-
-
Brudecki, L.1
Ferguson, D.A.2
McCall, C.E.3
El Gazzar, M.4
-
21
-
-
77954399377
-
Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function
-
Sander LE, Sackett SD, Dierssen U, et al. Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function. J Exp Med. 2010 ; 207: 1453-1464
-
(2010)
J Exp Med
, vol.207
, pp. 1453-1464
-
-
Sander, L.E.1
Sackett, S.D.2
Dierssen, U.3
-
22
-
-
78650756969
-
Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function
-
Condamine T, Gabrilovich DI. Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. Trends Immunol. 2011 ; 32: 19-25
-
(2011)
Trends Immunol
, vol.32
, pp. 19-25
-
-
Condamine, T.1
Gabrilovich, D.I.2
-
23
-
-
59849126377
-
Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1
-
Li H, Han Y, Guo Q, et al. Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J Immunol. 2009 ; 182: 240-249
-
(2009)
J Immunol
, vol.182
, pp. 240-249
-
-
Li, H.1
Han, Y.2
Guo, Q.3
-
24
-
-
54049134747
-
Subsets of myeloid-derived suppressor cells in tumor-bearing mice
-
Youn JI, Nagaraj S, Collazo M, Gabrilovich DI. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol. 2008 ; 181: 5791-5802
-
(2008)
J Immunol
, vol.181
, pp. 5791-5802
-
-
Youn, J.I.1
Nagaraj, S.2
Collazo, M.3
Gabrilovich, D.I.4
-
25
-
-
78649598159
-
Pivotal advance: Tumor-mediated induction of myeloid-derived suppressor cells and M2-polarized macrophages by altering intracellular PGE(2) catabolism in myeloid cells
-
Eruslanov E, Daurkin I, Ortiz J, et al. Pivotal advance: Tumor-mediated induction of myeloid-derived suppressor cells and M2-polarized macrophages by altering intracellular PGE(2) catabolism in myeloid cells. J Leukoc Biol. 2010 ; 88: 839-848
-
(2010)
J Leukoc Biol
, vol.88
, pp. 839-848
-
-
Eruslanov, E.1
Daurkin, I.2
Ortiz, J.3
-
26
-
-
34250359119
-
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis
-
Delano MJ, Scumpia PO, Weinstein JS, et al. MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med. 2007 ; 204: 1463-1474
-
(2007)
J Exp Med
, vol.204
, pp. 1463-1474
-
-
Delano, M.J.1
Scumpia, P.O.2
Weinstein, J.S.3
-
27
-
-
43249130187
-
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity
-
Movahedi K, Guilliams M, Van den Bossche J, et al. Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood. 2008 ; 111: 4233-4244
-
(2008)
Blood
, vol.111
, pp. 4233-4244
-
-
Movahedi, K.1
Guilliams, M.2
Van Den Bossche, J.3
-
28
-
-
84862127053
-
Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression
-
Ostrand-Rosenberg S, Sinha P, Beury DW, Clements VK. Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression. Semin Cancer Biol. 2012 ; 22: 275-281
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 275-281
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
Beury, D.W.3
Clements, V.K.4
-
29
-
-
79951793550
-
In vivo suppressive function of myeloid-derived suppressor cells is limited to the inflammatory site
-
Haverkamp JM, Crist SA, Elzey BD, et al. In vivo suppressive function of myeloid-derived suppressor cells is limited to the inflammatory site. Eur J Immunol. 2011 ; 41: 749-759
-
(2011)
Eur J Immunol
, vol.41
, pp. 749-759
-
-
Haverkamp, J.M.1
Crist, S.A.2
Elzey, B.D.3
-
30
-
-
77951073272
-
IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia
-
Ueda Y, Cain DW, Kuraoka M, et al. IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia. J Immunol. 2009 ; 182: 6477-6484
-
(2009)
J Immunol
, vol.182
, pp. 6477-6484
-
-
Ueda, Y.1
Cain, D.W.2
Kuraoka, M.3
-
31
-
-
22344437262
-
Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow
-
Ueda Y, Kondo M, Kelsoe G. Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow. J Exp Med. 2005 ; 201: 1771-1780
-
(2005)
J Exp Med
, vol.201
, pp. 1771-1780
-
-
Ueda, Y.1
Kondo, M.2
Kelsoe, G.3
-
32
-
-
58149332680
-
Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma
-
Kusmartsev S, Su Z, Heiser A, et al. Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma. Clin Cancer Res. 2008 ; 14: 8270-8278
-
(2008)
Clin Cancer Res
, vol.14
, pp. 8270-8278
-
-
Kusmartsev, S.1
Su, Z.2
Heiser, A.3
-
33
-
-
84874211785
-
Myeloid-derived suppressor cells: Mechanisms of action and recent advances in their role in transplant tolerance
-
Dilek N, Vuillefroy de SR, Blancho G, Vanhove B. Myeloid-derived suppressor cells: mechanisms of action and recent advances in their role in transplant tolerance. Front Immunol. 2012 ; 3: 208-208
-
(2012)
Front Immunol
, vol.3
, pp. 208-208
-
-
Dilek, N.1
Vuillefroy De, S.R.2
Blancho, G.3
Vanhove, B.4
-
34
-
-
77953141534
-
Immature immunosuppressive CD14+HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign
-
Poschke I, Mougiakakos D, Hansson J, et al. Immature immunosuppressive CD14+HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign. Cancer Res. 2010 ; 70: 4335-4345
-
(2010)
Cancer Res
, vol.70
, pp. 4335-4345
-
-
Poschke, I.1
Mougiakakos, D.2
Hansson, J.3
-
35
-
-
46049098560
-
A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells
-
Hoechst B, Ormandy LA, Ballmaier M, et al. A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells. Gastroenterology. 2008 ; 135: 234-243
-
(2008)
Gastroenterology
, vol.135
, pp. 234-243
-
-
Hoechst, B.1
Ormandy, L.A.2
Ballmaier, M.3
-
36
-
-
33749461167
-
All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients
-
Mirza N, Fishman M, Fricke I, et al. All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients. Cancer Res. 2006 ; 66: 9299-9307
-
(2006)
Cancer Res
, vol.66
, pp. 9299-9307
-
-
Mirza, N.1
Fishman, M.2
Fricke, I.3
-
38
-
-
3042767202
-
MicroRNAs: Small RNAs with a big role in gene regulation
-
He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004 ; 5: 522-531
-
(2004)
Nat Rev Genet
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
39
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004 ; 116: 281-297
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
40
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros V. The functions of animal microRNAs. Nature. 2004 ; 431: 350-355
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
41
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009 ; 136: 215-233
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
42
-
-
33644768174
-
Control of translation and mRNA degradation by miRNAs and siRNAs
-
Valencia-Sanchez MA, Liu J, Hannon GJ, Parker R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev. 2006 ; 20: 515-524
-
(2006)
Genes Dev
, vol.20
, pp. 515-524
-
-
Valencia-Sanchez, M.A.1
Liu, J.2
Hannon, G.J.3
Parker, R.4
-
43
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
-
Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?. Nat Rev Genet. 2008 ; 9: 102-114
-
(2008)
Nat Rev Genet
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
Bhattacharyya, S.N.2
Sonenberg, N.3
-
44
-
-
39749110034
-
Functional aspects of animal microRNAs
-
Williams AE. Functional aspects of animal microRNAs. Cell Mol Life Sci. 2008 ; 65: 545-562
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 545-562
-
-
Williams, A.E.1
-
45
-
-
33644779735
-
The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation
-
Naguibneva I, Ameyar-Zazoua M, Polesskaya A, et al. The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation. Nat Cell Biol. 2006 ; 8: 278-284
-
(2006)
Nat Cell Biol
, vol.8
, pp. 278-284
-
-
Naguibneva, I.1
Ameyar-Zazoua, M.2
Polesskaya, A.3
-
46
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen CZ, Li L, Lodish HF, Bartel DP. MicroRNAs modulate hematopoietic lineage differentiation. Science. 2004 ; 303: 83-86
-
(2004)
Science
, vol.303
, pp. 83-86
-
-
Chen, C.Z.1
Li, L.2
Lodish, H.F.3
Bartel, D.P.4
-
48
-
-
84863723933
-
MicroRNAs regulatory networks in myeloid lineage development and differentiation: Regulators of the regulators
-
El Gazzar M, McCall CE. MicroRNAs regulatory networks in myeloid lineage development and differentiation: regulators of the regulators. Immunol Cell Biol. 2012 ; 90: 587-593
-
(2012)
Immunol Cell Biol
, vol.90
, pp. 587-593
-
-
El Gazzar, M.1
McCall, C.E.2
-
49
-
-
70249129354
-
MicroRNAs in normal and malignant myelopoiesis
-
Pelosi E, Labbaye C, Testa U. MicroRNAs in normal and malignant myelopoiesis. Leuk Res. 2009 ; 33: 1584-1593
-
(2009)
Leuk Res
, vol.33
, pp. 1584-1593
-
-
Pelosi, E.1
Labbaye, C.2
Testa, U.3
-
50
-
-
50849104285
-
Mechanisms of microRNA deregulation in human cancer
-
Deng S, Calin GA, Croce CM, et al. Mechanisms of microRNA deregulation in human cancer. Cell Cycle. 2008 ; 7: 2643-2646
-
(2008)
Cell Cycle
, vol.7
, pp. 2643-2646
-
-
Deng, S.1
Calin, G.A.2
Croce, C.M.3
-
51
-
-
79953185385
-
MicroRNA: Potential targets for the development of novel drugs?
-
Wu W. MicroRNA: potential targets for the development of novel drugs?. Drugs R D. 2010 ; 10: 1-8
-
(2010)
Drugs R D
, vol.10
, pp. 1-8
-
-
Wu, W.1
-
52
-
-
84876744817
-
Epigenetic deregulation of microRNAs: New opportunities to target oncogenic signaling pathways in hepatocellular carcinoma
-
Yu Z, Cheng AS. Epigenetic deregulation of microRNAs: new opportunities to target oncogenic signaling pathways in hepatocellular carcinoma. Curr Pharm Des. 2013 ; 19: 1192-1200
-
(2013)
Curr Pharm des
, vol.19
, pp. 1192-1200
-
-
Yu, Z.1
Cheng, A.S.2
-
53
-
-
35748979703
-
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein
-
Fazi F, Racanicchi S, Zardo G, et al. Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. Cancer Cell. 2007 ; 12: 457-466
-
(2007)
Cancer Cell
, vol.12
, pp. 457-466
-
-
Fazi, F.1
Racanicchi, S.2
Zardo, G.3
-
54
-
-
80052936529
-
MicroRNA function in myeloid biology
-
O'Connell RM, Zhao JL, Rao DS. MicroRNA function in myeloid biology. Blood. 2011 ; 118: 2960-2969
-
(2011)
Blood
, vol.118
, pp. 2960-2969
-
-
O'Connell, R.M.1
Zhao, J.L.2
Rao, D.S.3
-
55
-
-
79958257077
-
MiR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
-
Boldin MP, Taganov KD, Rao DS, et al. miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J Exp Med. 2011 ; 208: 1189-1201
-
(2011)
J Exp Med
, vol.208
, pp. 1189-1201
-
-
Boldin, M.P.1
Taganov, K.D.2
Rao, D.S.3
-
56
-
-
79959362128
-
NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies
-
Zhao JL, Rao DS, Boldin MP, et al. NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies. Proc Natl Acad Sci USA. 2011 ; 108: 9184-9189
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 9184-9189
-
-
Zhao, J.L.1
Rao, D.S.2
Boldin, M.P.3
-
57
-
-
79251585937
-
The prognostic and functional role of microRNAs in acute myeloid leukemia
-
Marcucci G, Mrozek K, Radmacher MD, et al. The prognostic and functional role of microRNAs in acute myeloid leukemia. Blood. 2011 ; 117: 1121-1129
-
(2011)
Blood
, vol.117
, pp. 1121-1129
-
-
Marcucci, G.1
Mrozek, K.2
Radmacher, M.D.3
-
58
-
-
47849125676
-
MicroRNAs: New regulators of immune cell development and function
-
Baltimore D, Boldin MP, O'Connell RM, et al. MicroRNAs: new regulators of immune cell development and function. Nat Immunol. 2008 ; 9: 839-845
-
(2008)
Nat Immunol
, vol.9
, pp. 839-845
-
-
Baltimore, D.1
Boldin, M.P.2
O'Connell, R.M.3
-
59
-
-
66549105485
-
Gfi1 regulates miR-21 and miR-196b to control myelopoiesis
-
Velu CS, Baktula AM, Grimes HL. Gfi1 regulates miR-21 and miR-196b to control myelopoiesis. Blood. 2009 ; 113: 4720-4728
-
(2009)
Blood
, vol.113
, pp. 4720-4728
-
-
Velu, C.S.1
Baktula, A.M.2
Grimes, H.L.3
-
60
-
-
28344438648
-
A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis
-
Fazi F, Rosa A, Fatica A, et al. A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell. 2005 ; 123: 819-831
-
(2005)
Cell
, vol.123
, pp. 819-831
-
-
Fazi, F.1
Rosa, A.2
Fatica, A.3
-
61
-
-
45549103746
-
MicroRNAs and the immune response
-
Lindsay MA. microRNAs and the immune response. Trends Immunol. 2008 ; 29: 343-351
-
(2008)
Trends Immunol
, vol.29
, pp. 343-351
-
-
Lindsay, M.A.1
-
62
-
-
84861148197
-
Regulation of monocyte functional heterogeneity by miR-146a and Relb
-
Etzrodt M, Cortez-Retamozo V, Newton A, et al. Regulation of monocyte functional heterogeneity by miR-146a and Relb. Cell Rep. 2012 ; 1: 317-324
-
(2012)
Cell Rep
, vol.1
, pp. 317-324
-
-
Etzrodt, M.1
Cortez-Retamozo, V.2
Newton, A.3
-
63
-
-
33749425534
-
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells
-
Gallina G, Dolcetti L, Serafini P, et al. Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest. 2006 ; 116: 2777-2790
-
(2006)
J Clin Invest
, vol.116
, pp. 2777-2790
-
-
Gallina, G.1
Dolcetti, L.2
Serafini, P.3
-
64
-
-
42249090353
-
MiR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism
-
Fujita S, Ito T, Mizutani T, et al. miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism. J Mol Biol. 2008 ; 378: 492-504
-
(2008)
J Mol Biol
, vol.378
, pp. 492-504
-
-
Fujita, S.1
Ito, T.2
Mizutani, T.3
-
65
-
-
75649113377
-
Negative regulation of TLR4 via targeting of the pro-inflammatory tumor suppressor PDCD4 by the microRNA miR-21
-
Sheedy FJ, Palsson-McDermott E, Hennessy EJ, et al. Negative regulation of TLR4 via targeting of the pro-inflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol. 2010 ; 11: 141-147
-
(2010)
Nat Immunol
, vol.11
, pp. 141-147
-
-
Sheedy, F.J.1
Palsson-Mcdermott, E.2
Hennessy, E.J.3
-
66
-
-
77956339881
-
OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
-
Medina PP, Nolde M, Slack FJ. OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature. 2010 ; 467: 86-90
-
(2010)
Nature
, vol.467
, pp. 86-90
-
-
Medina, P.P.1
Nolde, M.2
Slack, F.J.3
-
67
-
-
77955992756
-
STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer
-
Iliopoulos D, Jaeger SA, Hirsch HA, et al. STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol Cell. 2010 ; 39: 493-506
-
(2010)
Mol Cell
, vol.39
, pp. 493-506
-
-
Iliopoulos, D.1
Jaeger, S.A.2
Hirsch, H.A.3
-
69
-
-
40249100094
-
Mutations in growth factor independent-1 associated with human neutropenia block murine granulopoiesis through colony stimulating factor-1
-
Zarebski A, Velu CS, Baktula AM, et al. Mutations in growth factor independent-1 associated with human neutropenia block murine granulopoiesis through colony stimulating factor-1. Immunity. 2008 ; 28: 370-380
-
(2008)
Immunity
, vol.28
, pp. 370-380
-
-
Zarebski, A.1
Velu, C.S.2
Baktula, A.M.3
-
70
-
-
77950095763
-
TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
-
Wang B, Hsu SH, Majumder S, et al. TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene. 2010 ; 29: 1787-1797
-
(2010)
Oncogene
, vol.29
, pp. 1787-1797
-
-
Wang, B.1
Hsu, S.H.2
Majumder, S.3
-
71
-
-
34249331209
-
MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia
-
Garzon R, Pichiorri F, Palumbo T, et al. MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia. Oncogene. 2007 ; 26: 4148-4157
-
(2007)
Oncogene
, vol.26
, pp. 4148-4157
-
-
Garzon, R.1
Pichiorri, F.2
Palumbo, T.3
-
73
-
-
77957725130
-
STAT3 controls myeloid progenitor growth during emergency granulopoiesis
-
Zhang H, Nguyen-Jackson H, Panopoulos AD, et al. STAT3 controls myeloid progenitor growth during emergency granulopoiesis. Blood. 2010 ; 116: 2462-2471
-
(2010)
Blood
, vol.116
, pp. 2462-2471
-
-
Zhang, H.1
Nguyen-Jackson, H.2
Panopoulos, A.D.3
-
74
-
-
0031987330
-
Essential roles for granulocyte-macrophage colony-stimulating factor (G-CSF) and G-CSF in the sustained hematopoietic response of Listeria monocytogenes-infected mice
-
Zhan Y, Lieschke GJ, Grail D, et al. Essential roles for granulocyte-macrophage colony-stimulating factor (G-CSF) and G-CSF in the sustained hematopoietic response of Listeria monocytogenes-infected mice. Blood. 1998 ; 91: 863-869
-
(1998)
Blood
, vol.91
, pp. 863-869
-
-
Zhan, Y.1
Lieschke, G.J.2
Grail, D.3
-
75
-
-
33745225494
-
C/EBPbeta is required for 'emergency' granulopoiesis
-
Hirai H, Zhang P, Dayaram T, et al. C/EBPbeta is required for 'emergency' granulopoiesis. Nat Immunol. 2006 ; 7: 732-739
-
(2006)
Nat Immunol
, vol.7
, pp. 732-739
-
-
Hirai, H.1
Zhang, P.2
Dayaram, T.3
-
76
-
-
77953914366
-
Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor
-
Marigo I, Bosio E, Solito S, et al. Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. Immunity. 2010 ; 32: 790-802
-
(2010)
Immunity
, vol.32
, pp. 790-802
-
-
Marigo, I.1
Bosio, E.2
Solito, S.3
-
77
-
-
84858722006
-
MicroRNAs, new effectors and regulators of NF-kappaB
-
Boldin MP, Baltimore D. MicroRNAs, new effectors and regulators of NF-kappaB. Immunol Rev. 2012 ; 246: 205-220
-
(2012)
Immunol Rev
, vol.246
, pp. 205-220
-
-
Boldin, M.P.1
Baltimore, D.2
-
78
-
-
41149130219
-
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder
-
O'Connell RM, Rao DS, Chaudhuri AA, et al. Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med. 2008 ; 205: 585-594
-
(2008)
J Exp Med
, vol.205
, pp. 585-594
-
-
O'Connell, R.M.1
Rao, D.S.2
Chaudhuri, A.A.3
-
80
-
-
41649119008
-
Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin
-
Garzon R, Garofalo M, Martelli MP, et al. Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin. Proc Natl Acad Sci USA. 2008 ; 105: 3945-3950
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3945-3950
-
-
Garzon, R.1
Garofalo, M.2
Martelli, M.P.3
-
81
-
-
25444457833
-
MicroRNAs: Critical regulators of development, cellular physiology and malignancy
-
Mendell JT. MicroRNAs: critical regulators of development, cellular physiology and malignancy. Cell Cycle. 2005 ; 4: 1179-1184
-
(2005)
Cell Cycle
, vol.4
, pp. 1179-1184
-
-
Mendell, J.T.1
-
82
-
-
39749143354
-
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters
-
Ventura A, Young AG, Winslow MM, et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell. 2008 ; 132: 875-886
-
(2008)
Cell
, vol.132
, pp. 875-886
-
-
Ventura, A.1
Young, A.G.2
Winslow, M.M.3
-
83
-
-
79955022118
-
Both miR-17-5p and miR-20a alleviate suppressive potential of myeloid-derived suppressor cells by modulating STAT3 expression
-
Zhang M, Liu Q, Mi S, et al. Both miR-17-5p and miR-20a alleviate suppressive potential of myeloid-derived suppressor cells by modulating STAT3 expression. J Immunol. 2011 ; 186: 4716-4724
-
(2011)
J Immunol
, vol.186
, pp. 4716-4724
-
-
Zhang, M.1
Liu, Q.2
Mi, S.3
-
84
-
-
38049146022
-
The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation
-
Rosa A, Ballarino M, Sorrentino A, et al. The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation. Proc Natl Acad Sci USA. 2007 ; 104: 19849-19854
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19849-19854
-
-
Rosa, A.1
Ballarino, M.2
Sorrentino, A.3
-
85
-
-
42749095242
-
Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts
-
Kuhn DE, Nuovo GJ, Martin MM, et al. Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts. Biochem Biophys Res Commun. 2008 ; 370: 473-477
-
(2008)
Biochem Biophys Res Commun
, vol.370
, pp. 473-477
-
-
Kuhn, D.E.1
Nuovo, G.J.2
Martin, M.M.3
-
86
-
-
1942494040
-
Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
-
Sempere LF, Freemantle S, Pitha-Rowe I, et al. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 2004 ; 5: R13 - R13
-
(2004)
Genome Biol
, vol.5
-
-
Sempere, L.F.1
Freemantle, S.2
Pitha-Rowe, I.3
-
87
-
-
77956270732
-
MicroRNA miR-125a controls hematopoietic stem cell number
-
Guo S, Lu J, Schlanger R, et al. MicroRNA miR-125a controls hematopoietic stem cell number. Proc Natl Acad Sci USA. 2010 ; 107: 14229-14234
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14229-14234
-
-
Guo, S.1
Lu, J.2
Schlanger, R.3
-
88
-
-
77649143631
-
MiR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia
-
Klusmann JH, Li Z, Bohmer K, et al. miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia. Genes Dev. 2010 ; 24: 478-490
-
(2010)
Genes Dev
, vol.24
, pp. 478-490
-
-
Klusmann, J.H.1
Li, Z.2
Bohmer, K.3
-
89
-
-
58149145653
-
Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation
-
Bousquet M, Quelen C, Rosati R, et al. Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation. J Exp Med. 2008 ; 205: 2499-2506
-
(2008)
J Exp Med
, vol.205
, pp. 2499-2506
-
-
Bousquet, M.1
Quelen, C.2
Rosati, R.3
-
90
-
-
83555166166
-
Emu/miR-125b transgenic mice develop lethal B-cell malignancies
-
Enomoto Y, Kitaura J, Hatakeyama K, et al. Emu/miR-125b transgenic mice develop lethal B-cell malignancies. Leukemia. 2011 ; 25: 1849-1856
-
(2011)
Leukemia
, vol.25
, pp. 1849-1856
-
-
Enomoto, Y.1
Kitaura, J.2
Hatakeyama, K.3
-
91
-
-
84858257170
-
Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A
-
Chaudhuri AA, So AY, Mehta A, et al. Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A. Proc Natl Acad Sci USA. 2012 ; 109: 4233-4238
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 4233-4238
-
-
Chaudhuri, A.A.1
So, A.Y.2
Mehta, A.3
-
92
-
-
68649091506
-
The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs
-
Androulidaki A, Iliopoulos D, Arranz A, et al. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity. 2009 ; 31: 220-231
-
(2009)
Immunity
, vol.31
, pp. 220-231
-
-
Androulidaki, A.1
Iliopoulos, D.2
Arranz, A.3
-
93
-
-
38049030287
-
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/ TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
-
Tili E, Michaille JJ, Cimino A, et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol. 2007 ; 179: 5082-5089
-
(2007)
J Immunol
, vol.179
, pp. 5082-5089
-
-
Tili, E.1
Michaille, J.J.2
Cimino, A.3
-
94
-
-
79954997645
-
MiR-223 suppresses differentiation of tumor-induced CD11b(+) Gr1(+) myeloid-derived suppressor cells from bone marrow cells
-
Liu Q, Zhang M, Jiang X, et al. miR-223 suppresses differentiation of tumor-induced CD11b(+) Gr1(+) myeloid-derived suppressor cells from bone marrow cells. Int J Cancer. 2011 ; 129: 2662-2673
-
(2011)
Int J Cancer
, vol.129
, pp. 2662-2673
-
-
Liu, Q.1
Zhang, M.2
Jiang, X.3
-
95
-
-
0030031409
-
Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6
-
Chen PL, Riley DJ, Chen-Kiang S, Lee WH. Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6. Proc Natl Acad Sci USA. 1996 ; 93: 465-469
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 465-469
-
-
Chen, P.L.1
Riley, D.J.2
Chen-Kiang, S.3
Lee, W.H.4
-
96
-
-
0037071397
-
Transcriptional regulation of granulocyte and monocyte development
-
Friedman AD. Transcriptional regulation of granulocyte and monocyte development. Oncogene. 2002 ; 21: 3377-3390
-
(2002)
Oncogene
, vol.21
, pp. 3377-3390
-
-
Friedman, A.D.1
-
97
-
-
34247483919
-
An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling
-
Fukao T, Fukuda Y, Kiga K, et al. An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling. Cell. 2007 ; 129: 617-631
-
(2007)
Cell
, vol.129
, pp. 617-631
-
-
Fukao, T.1
Fukuda, Y.2
Kiga, K.3
-
98
-
-
84862074482
-
MicroRNA-494 is required for the accumulation and functions of tumor-expanded myeloid-derived suppressor cells via targeting of PTEN
-
Liu Y, Lai L, Chen Q, et al. MicroRNA-494 is required for the accumulation and functions of tumor-expanded myeloid-derived suppressor cells via targeting of PTEN. J Immunol. 2012 ; 188: 5500-5510
-
(2012)
J Immunol
, vol.188
, pp. 5500-5510
-
-
Liu, Y.1
Lai, L.2
Chen, Q.3
-
99
-
-
38949171376
-
MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components
-
Asirvatham AJ, Gregorie CJ, Hu Z, et al. MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components. Mol Immunol. 2008 ; 45: 1995-2006
-
(2008)
Mol Immunol
, vol.45
, pp. 1995-2006
-
-
Asirvatham, A.J.1
Gregorie, C.J.2
Hu, Z.3
|