-
1
-
-
0032161624
-
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
-
Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dötsch V, Andrews NC, Caput D, and McKeon F. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell. 1998; 2: 305-316.
-
(1998)
Mol Cell.
, vol.2
, pp. 305-316
-
-
Yang, A.1
Kaghad, M.2
Wang, Y.3
Gillett, E.4
Fleming, M.D.5
Dötsch, V.6
Andrews, N.C.7
Caput, D.8
McKeon, F.9
-
2
-
-
0942301281
-
p63 is the molecular switch for initiation of an epithelial stratification program
-
Koster MI, Kim S, Mills AA, DeMayo FJ, and Roop DR. p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev. 2004; 18: 126-131.
-
(2004)
Genes Dev.
, vol.18
, pp. 126-131
-
-
Koster, M.I.1
Kim, S.2
Mills, A.A.3
DeMayo, F.J.4
Roop, D.R.5
-
3
-
-
33751230475
-
p63 regulates proliferation and differentiation of developmentally mature keratinocytes
-
Truong AB, Kretz M, Ridky TW, Kimmel R, and Khavari PA. p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev. 2006; 20: 3185-3197.
-
(2006)
Genes Dev.
, vol.20
, pp. 3185-3197
-
-
Truong, A.B.1
Kretz, M.2
Ridky, T.W.3
Kimmel, R.4
Khavari, P.A.5
-
4
-
-
34247511981
-
p63 Is essential for the proliferative potential of stem cells in stratified epithelia
-
Senoo M, Pinto F, Crum CP, and McKeon F. p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell. 2007; 129: 523-536.
-
(2007)
Cell.
, vol.129
, pp. 523-536
-
-
Senoo, M.1
Pinto, F.2
Crum, C.P.3
McKeon, F.4
-
5
-
-
0036187907
-
p63 expression profiles in human normal and tumor tissues
-
Di Como CJ, Urist MJ, Babayan I, Drobnjak M, Hedvat CV, Teruya-Feldstein J, Pohar K, Hoos A, and Cordon- Cardo C. p63 expression profiles in human normal and tumor tissues. Clin Cancer Res. 2002; 8: 494-501.
-
(2002)
Clin Cancer Res.
, vol.8
, pp. 494-501
-
-
Di Como, C.J.1
Urist, M.J.2
Babayan, I.3
Drobnjak, M.4
Hedvat, C.V.5
Teruya-Feldstein, J.6
Pohar, K.7
Hoos, A.8
Cordon-Cardo, C.9
-
6
-
-
30644474977
-
p63: oncogene or tumor suppressor?
-
Mills AA. p63: oncogene or tumor suppressor? Curr Opin Genet Dev. 2006; 16: 38-44.
-
(2006)
Curr Opin Genet Dev.
, vol.16
, pp. 38-44
-
-
Mills, A.A.1
-
7
-
-
84873044188
-
p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis
-
Su X, Chakravarti D, and Flores ER. p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis. Nat Rev Cancer. 2013; 13: 136-143.
-
(2013)
Nat Rev Cancer.
, vol.13
, pp. 136-143
-
-
Su, X.1
Chakravarti, D.2
Flores, E.R.3
-
8
-
-
84867692492
-
DeltaNp63alpha represses anti-proliferative genes via H2A.Z deposition
-
Gallant-Behm CL, Ramsey MR, Bensard CL, Nojek I, Tran J, Liu M, Ellisen LW, and Espinosa JM. DeltaNp63alpha represses anti-proliferative genes via H2A.Z deposition. Genes Dev. 2012; 26: 2325-2336.
-
(2012)
Genes Dev.
, vol.26
, pp. 2325-2336
-
-
Gallant-Behm, C.L.1
Ramsey, M.R.2
Bensard, C.L.3
Nojek, I.4
Tran, J.5
Liu, M.6
Ellisen, L.W.7
Espinosa, J.M.8
-
9
-
-
81155137696
-
DeltaNp63alpha regulates keratinocyte proliferation by controlling PTEN expression and localization
-
Leonard MK, Kommagani R, Payal V, Mayo LD, Shamma HN, and Kadakia MP. DeltaNp63alpha regulates keratinocyte proliferation by controlling PTEN expression and localization. Cell Death Differ. 2011; 18: 1924-1933.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 1924-1933
-
-
Leonard, M.K.1
Kommagani, R.2
Payal, V.3
Mayo, L.D.4
Shamma, H.N.5
Kadakia, M.P.6
-
10
-
-
13444250890
-
DeltaNp63alpha up-regulates the Hsp70 gene in human cancer
-
Wu G, Osada M, Guo Z, Fomenkov A, Begum S, Zhao M, Upadhyay S, Xing M, Wu F, Moon C, Westra WH, Koch WM, Mantovani R, Califano JA, Ratovitski E, Sidransky D, and Trink B. DeltaNp63alpha up-regulates the Hsp70 gene in human cancer. Cancer Res. 2005; 65: 758-766.
-
(2005)
Cancer Res.
, vol.65
, pp. 758-766
-
-
Wu, G.1
Osada, M.2
Guo, Z.3
Fomenkov, A.4
Begum, S.5
Zhao, M.6
Upadhyay, S.7
Xing, M.8
Wu, F.9
Moon, C.10
Westra, W.H.11
Koch, W.M.12
Mantovani, R.13
Califano, J.A.14
Ratovitski, E.15
Sidransky, D.16
Trink, B.17
-
12
-
-
73349088166
-
TAp63 induces senescence and suppresses tumorigenesis in vivo
-
Guo X, Keyes WM, Papazoglu C, Zuber J, Li W, Lowe SW, Vogel H, and Mills AA. TAp63 induces senescence and suppresses tumorigenesis in vivo. Nat Cell Biol. 2009; 11: 1451-1457.
-
(2009)
Nat Cell Biol.
, vol.11
, pp. 1451-1457
-
-
Guo, X.1
Keyes, W.M.2
Papazoglu, C.3
Zuber, J.4
Li, W.5
Lowe, S.W.6
Vogel, H.7
Mills, A.A.8
-
13
-
-
77958558613
-
TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs
-
Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin YL, Leung ML, El-Naggar A, Creighton CJ, Suraokar MB, Wistuba I, and Flores ER. TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature. 2010; 467: 986-990.
-
(2010)
Nature.
, vol.467
, pp. 986-990
-
-
Su, X.1
Chakravarti, D.2
Cho, M.S.3
Liu, L.4
Gi, Y.J.5
Lin, Y.L.6
Leung, M.L.7
El-Naggar, A.8
Creighton, C.J.9
Suraokar, M.B.10
Wistuba, I.11
Flores, E.R.12
-
14
-
-
84890242833
-
TAp63 regulates oncogenic miR-155 to mediate migration and tumor growth
-
Mattiske S, Ho K, Noll JE, Neilsen PM, Callen DF, and Suetani RJ. TAp63 regulates oncogenic miR-155 to mediate migration and tumor growth. Oncotarget. 2013; 4: 1894- 1903.
-
(2013)
Oncotarget.
, vol.4
-
-
Mattiske, S.1
Ho, K.2
Noll, J.E.3
Neilsen, P.M.4
Callen, D.F.5
Suetani, R.J.6
-
15
-
-
33645393209
-
Recent advances in the research and development of human defensins
-
Chen H, Xu Z, Peng L, Fang X, Yin X, Xu N, and Cen P. Recent advances in the research and development of human defensins. Peptides. 2006; 27: 931-940.
-
(2006)
Peptides.
, vol.27
, pp. 931-940
-
-
Chen, H.1
Xu, Z.2
Peng, L.3
Fang, X.4
Yin, X.5
Xu, N.6
Cen, P.7
-
16
-
-
0141799911
-
Defensins: antimicrobial peptides of innate immunity
-
Ganz T. Defensins: antimicrobial peptides of innate immunity. Nat Rev Immunol. 2003; 3: 710-720.
-
(2003)
Nat Rev Immunol.
, vol.3
, pp. 710-720
-
-
Ganz, T.1
-
17
-
-
33745698864
-
Defensins in innate antiviral immunity
-
Klotman ME and Chang TL. Defensins in innate antiviral immunity. Nat Rev Immunol. 2006; 6: 447-456.
-
(2006)
Nat Rev Immunol.
, vol.6
, pp. 447-456
-
-
Klotman, M.E.1
Chang, T.L.2
-
18
-
-
34548476495
-
Defensins induce the recruitment of dendritic cells in cervical human papillomavirus-associated (pre)neoplastic lesions formed in vitro and transplanted in vivo
-
Hubert P, Herman L, Maillard C, Caberg JH, Nikkels A, Pierard G, Foidart JM, Noel A, Boniver J, and Delvenne P. Defensins induce the recruitment of dendritic cells in cervical human papillomavirus-associated (pre)neoplastic lesions formed in vitro and transplanted in vivo. FASEB J. 2007; 21: 2765-2775.
-
(2007)
FASEB J.
, vol.21
, pp. 2765-2775
-
-
Hubert, P.1
Herman, L.2
Maillard, C.3
Caberg, J.H.4
Nikkels, A.5
Pierard, G.6
Foidart, J.M.7
Noel, A.8
Boniver, J.9
Delvenne, P.10
-
19
-
-
0033844287
-
Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells
-
Yang D, Chen Q, Chertov O and Oppenheim JJ. Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells. J Leukoc Biol. 2000; 68: 9-14.
-
(2000)
J Leukoc Biol.
, vol.68
, pp. 9-14
-
-
Yang, D.1
Chen, Q.2
Chertov, O.3
Oppenheim, J.J.4
-
20
-
-
0033569408
-
Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6
-
Yang D, Chertov O, Bykovskaia SN, Chen Q, Buffo MJ, Shogan J, Anderson M, Schröder JM, Wang JM, Howard OM, and Oppenheim JJ. Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science. 1999; 286: 525-528.
-
(1999)
Science.
, vol.286
, pp. 525-528
-
-
Yang, D.1
Chertov, O.2
Bykovskaia, S.N.3
Chen, Q.4
Buffo, M.J.5
Shogan, J.6
Anderson, M.7
Schröder, J.M.8
Wang, J.M.9
Howard, O.M.10
Oppenheim, J.J.11
-
21
-
-
84874205028
-
The yin and yang of human Beta-defensins in health and disease
-
Weinberg A, Jin G, Sieg S, and McCormick TS. The yin and yang of human Beta-defensins in health and disease. Front Immunol. 2012; 3: 294.
-
(2012)
Front Immunol.
, vol.3
, pp. 294
-
-
Weinberg, A.1
Jin, G.2
Sieg, S.3
McCormick, T.S.4
-
22
-
-
77956209435
-
An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis
-
Jin G, Kawsar HI, Hirsch SA, Zeng C, Jia X, Feng Z, Ghosh SK, Zheng QY, Zhou A, McIntyre TM, and Weinberg A. An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis. PLoS One. 2010; 5: e10993.
-
(2010)
PLoS One.
, vol.5
-
-
Jin, G.1
Kawsar, H.I.2
Hirsch, S.A.3
Zeng, C.4
Jia, X.5
Feng, Z.6
Ghosh, S.K.7
Zheng, Q.Y.8
Zhou, A.9
McIntyre, T.M.10
Weinberg, A.11
-
23
-
-
58149526865
-
Antimicrobial human beta-defensin 2 stimulates migration, proliferation and tube formation of human umbilical vein endothelial cells
-
Baroni A, Donnarumma G, Paoletti I, Longanesi-Cattani I, Bifulco K, Tufano MA, and Carriero MV. Antimicrobial human beta-defensin 2 stimulates migration, proliferation and tube formation of human umbilical vein endothelial cells. Peptides. 2009; 30: 267-272.
-
(2009)
Peptides.
, vol.30
, pp. 267-272
-
-
Baroni, A.1
Donnarumma, G.2
Paoletti, I.3
Longanesi-Cattani, I.4
Bifulco, K.5
Tufano, M.A.6
Carriero, M.V.7
-
24
-
-
33747872417
-
Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis
-
Barbieri CE, Tang LJ, Brown KA, and Pietenpol JA. Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis. Cancer Res. 2006; 66: 7589-7597.
-
(2006)
Cancer Res.
, vol.66
, pp. 7589-7597
-
-
Barbieri, C.E.1
Tang, L.J.2
Brown, K.A.3
Pietenpol, J.A.4
-
25
-
-
42249110348
-
Endoglin (CD105): a marker of tumor vasculature and potential target for therapy
-
Dallas NA, Samuel S, Xia L, Fan F, Gray MJ, Lim SJ, and Ellis LM. Endoglin (CD105): a marker of tumor vasculature and potential target for therapy. Clin Cancer Res. 2008; 14: 1931-1937.
-
(2008)
Clin Cancer Res.
, vol.14
, pp. 1931-1937
-
-
Dallas, N.A.1
Samuel, S.2
Xia, L.3
Fan, F.4
Gray, M.J.5
Lim, S.J.6
Ellis, L.M.7
-
26
-
-
80054773965
-
Integrins in tumor angiogenesis and lymphangiogenesis
-
Foubert P, and Varner JA. Integrins in tumor angiogenesis and lymphangiogenesis. Methods Mol Biol. 2012; 757: 471-486.
-
(2012)
Methods Mol Biol.
, vol.757
, pp. 471-486
-
-
Foubert, P.1
Varner, J.A.2
-
27
-
-
84858307271
-
Tumor lymphangiogenesis as a potential therapeutic target
-
Duong T, Koopman P, and Francois M. Tumor lymphangiogenesis as a potential therapeutic target. J Oncol 2012; 2012: 204946.
-
(2012)
J Oncol
, vol.2012
, pp. 204946
-
-
Duong, T.1
Koopman, P.2
Francois, M.3
-
28
-
-
0033898814
-
Presence of human betadefensin-in oral squamous cell carcinoma
-
Mizukawa N, Sawaki K, Yamachika E, Fukunaga J, Ueno T, Takagi S, and Sugahara T. Presence of human betadefensin-in oral squamous cell carcinoma. Anticancer Res. 2000; 20: 2005-2007.
-
(2000)
Anticancer Res
, vol.20
, pp. 2005-2007
-
-
Mizukawa, N.1
Sawaki, K.2
Yamachika, E.3
Fukunaga, J.4
Ueno, T.5
Takagi, S.6
Sugahara, T.7
-
29
-
-
77950571925
-
Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma
-
Herfs M, Hubert P, Suarez-Carmona M, Reschner A, Saussez S, Berx G, Savagner P, Boniver J, and Delvenne P. Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma. Am J Pathol. 2010; 176: 1941-1949.
-
(2010)
Am J Pathol.
, vol.176
, pp. 1941-1949
-
-
Herfs, M.1
Hubert, P.2
Suarez-Carmona, M.3
Reschner, A.4
Saussez, S.5
Berx, G.6
Savagner, P.7
Boniver, J.8
Delvenne, P.9
-
30
-
-
35148852661
-
Snail-induced down-regulation of DeltaNp63alpha acquires invasive phenotype of human squamous cell carcinoma
-
Higashikawa K, Yoneda S, Tobiume K, Taki M, Shigeishi H, and Kamata N. Snail-induced down-regulation of DeltaNp63alpha acquires invasive phenotype of human squamous cell carcinoma. Cancer Res. 2007; 67: 9207- 9213.
-
(2007)
Cancer Res.
, vol.67
-
-
Higashikawa, K.1
Yoneda, S.2
Tobiume, K.3
Taki, M.4
Shigeishi, H.5
Kamata, N.6
-
31
-
-
77956394519
-
Overexpression of p63 is associated with radiation resistance and prognosis in oral squamous cell carcinoma
-
Moergel M, Abt E, Stockinger M, and Kunkel M. Overexpression of p63 is associated with radiation resistance and prognosis in oral squamous cell carcinoma. Oral Oncol. 2010; 46: 667-671.
-
(2010)
Oral Oncol.
, vol.46
, pp. 667-671
-
-
Moergel, M.1
Abt, E.2
Stockinger, M.3
Kunkel, M.4
-
32
-
-
20044379201
-
p63 overexpression associates with poor prognosis in head and neck squamous cell carcinoma
-
Lo Muzio L, Santarelli Santarelli A, Caltabiano R, Rubini C, Pieramici T, Trevisiol L, Carinci F, Leonardi R, De Lillo A, Lanzafame S, Bufo P, and Piattelli A. p63 overexpression associates with poor prognosis in head and neck squamous cell carcinoma. Hum Pathol 2005; 36: 187- 194.
-
(2005)
Hum Pathol
, vol.36
-
-
Lo Muzio, L.1
Santarelli Santarelli, A.2
Caltabiano, R.3
Rubini, C.4
Pieramici, T.5
Trevisiol, L.6
Carinci, F.7
Leonardi, R.8
De Lillo, A.9
Lanzafame, S.10
Bufo, P.11
Piattelli, A.12
-
33
-
-
84875740623
-
p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis
-
Matin RN, Chikh A, Chong Chong SL, Mesher D, Graf M, Sanza' P, Senatore V, Scatolini M, Moretti F, Leigh IM, Proby CM, Costanzo A, Chiorino G, Cerio R, Harwood CA, and Bergamaschi D. p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis. J Exp Med. 2013; 210: 581-603.
-
(2013)
J Exp Med.
, vol.210
, pp. 581-603
-
-
Matin, R.N.1
Chikh, A.2
Chong Chong, S.L.3
Mesher, D.4
Graf, M.5
Sanza', P.6
Senatore, V.7
Scatolini, M.8
Moretti, F.9
Leigh, I.M.10
Proby, C.M.11
Costanzo, A.12
Chiorino, G.13
Cerio, R.14
Harwood, C.A.15
Bergamaschi, D.16
-
34
-
-
85020344705
-
TAp63gamma (p51A) and dNp63alpha (p73L), two major isoforms of the p63 gene, exert opposite effects on the vascular endothelial growth factor (VEGF) gene expression
-
Senoo M, Matsumura Y, and Habu S. TAp63gamma (p51A) and dNp63alpha (p73L), two major isoforms of the p63 gene, exert opposite effects on the vascular endothelial growth factor (VEGF) gene expression. Oncogene. 2002; 21: 2455-2465.
-
(2002)
Oncogene.
, vol.21
, pp. 2455-2465
-
-
Senoo, M.1
Matsumura, Y.2
Habu, S.3
-
35
-
-
84892692849
-
δNp63 Promotes Pediatric Neuroblastoma and Osteosarcoma by Regulating Tumor Angiogenesis
-
Bid HK, Roberts RD, Cam M, Audino A, Kurmasheva RT, Lin J, Houghton PJ, and Cam H. δNp63 Promotes Pediatric Neuroblastoma and Osteosarcoma by Regulating Tumor Angiogenesis. Cancer Res. 2014; 74: 320-329.
-
(2014)
Cancer Res.
, vol.74
, pp. 320-329
-
-
Bid, H.K.1
Roberts, R.D.2
Cam, M.3
Audino, A.4
Kurmasheva, R.T.5
Lin, J.6
Houghton, P.J.7
Cam, H.8
-
36
-
-
84861117223
-
Mouse beta-defensin 14 (Defb14) promotes tumor growth by inducing angiogenesis in a CCR6-dependent manner
-
Rohrl J, Huber B, Koehl GE, Geissler EK, and Hehlgans T. Mouse beta-defensin 14 (Defb14) promotes tumor growth by inducing angiogenesis in a CCR6-dependent manner. J Immunol. 2012; 188: 4931-4939.
-
(2012)
J Immunol.
, vol.188
, pp. 4931-4939
-
-
Rohrl, J.1
Huber, B.2
Koehl, G.E.3
Geissler, E.K.4
Hehlgans, T.5
-
37
-
-
84863798101
-
Proinflammatory cytokines induce bronchial hyperplasia and squamous metaplasia in smokers: implications for chronic obstructive pulmonary disease therapy
-
Herfs M, Hubert P, Poirrier AL, Vandevenne P, Renoux V, Habraken Y, Cataldo D, Boniver J, and Delvenne P. Proinflammatory cytokines induce bronchial hyperplasia and squamous metaplasia in smokers: implications for chronic obstructive pulmonary disease therapy. Am J Respir Cell Mol Biol. 2012; 47: 67-79.
-
(2012)
Am J Respir Cell Mol Biol.
, vol.47
, pp. 67-79
-
-
Herfs, M.1
Hubert, P.2
Poirrier, A.L.3
Vandevenne, P.4
Renoux, V.5
Habraken, Y.6
Cataldo, D.7
Boniver, J.8
Delvenne, P.9
-
38
-
-
84872971035
-
A novel blueprint for 'top down' differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia
-
Herfs M, Vargas SO, Yamamoto Y, Howitt BE, Nucci MR, Hornick JL, McKeon FD, Xian W, and Crum CP. A novel blueprint for 'top down' differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia. J Pathol. 2013; 229: 460- 468.
-
(2013)
J Pathol.
, vol.229
-
-
Herfs, M.1
Vargas, S.O.2
Yamamoto, Y.3
Howitt, B.E.4
Nucci, M.R.5
Hornick, J.L.6
McKeon, F.D.7
Xian, W.8
Crum, C.P.9
-
39
-
-
43449136186
-
Transforming growth factor-beta1-mediated slug and snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression
-
Herfs M, Hubert P, Kholod N, Caberg JH, Gilles C, Berx G, Savagner P, Boniver J, and Delvenne P. Transforming growth factor-beta1-mediated slug and snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression. Am J Pathol. 2008; 172: 1391-1402.
-
(2008)
Am J Pathol.
, vol.172
, pp. 1391-1402
-
-
Herfs, M.1
Hubert, P.2
Kholod, N.3
Caberg, J.H.4
Gilles, C.5
Berx, G.6
Savagner, P.7
Boniver, J.8
Delvenne, P.9
|