A novel blueprint for 'top down' differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia

Journal of Pathology

Volumn 229, Issue 3, 2013, Pages 460-468

  Herfs, Michael ^a,b   Vargas, Sara O ^c   Yamamoto, Yusuke ^d   Howitt, Brooke E ^a   Nucci, Marisa R ^a   Hornick, Jason L ^a   McKeon, Frank D ^d,e   Xian, Wa ^a,f   Crum, Christopher P ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d GENOME INSTITUTE OF SINGAPORE   (Singapore)

^e HARVARD MEDICAL SCHOOL   (United States)

^f INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

Author keywords

cervix; development; HPV; metaplasia; neoplasia; squamocolumnar junction

Indexed keywords

ADULT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL POPULATION; CELL STRUCTURE; CHILD; DEVELOPMENT; DISEASE PREDISPOSITION; EARLY CANCER; EMBRYONIC STEM CELL; EPITHELIUM BASAL CELL; FEMALE; FETUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; METAPLASIA; MOUSE; NONHUMAN; PAPILLOMAVIRUS INFECTION; PRIORITY JOURNAL; REPRODUCTION; SQUAMOCOLUMNAR JUNCTION; SQUAMOUS CELL CARCINOMA; UTERINE CERVIX CANCER; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX EPITHELIUM;

ALPHAPAPILLOMAVIRUS; ANIMALS; CELL DIFFERENTIATION; CERVICAL INTRAEPITHELIAL NEOPLASIA; CERVIX UTERI; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; EPITHELIUM; FEMALE; HUMANS; METAPLASIA; MICE; MICE, INBRED BALB C; NEOPLASTIC STEM CELLS; PAPILLOMAVIRUS INFECTIONS; UTERINE CERVICAL DYSPLASIA; UTERINE CERVICAL NEOPLASMS;

EID: 84872971035     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4110     Document Type: Article

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