메뉴 건너뛰기




Volumn 40, Issue 3, 2014, Pages 504-515

Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder

Author keywords

adoption; copy number variants; family studies; GWAS; twin

Indexed keywords

ARTICLE; BIPOLAR DISORDER; BRIEF PSYCHOTIC DISORDER; DELUSIONAL DISORDER; DEPRESSIVE PSYCHOSIS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; MOLECULAR PHYLOGENY; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE GENETICS; SAMPLE SIZE; SCHIZOAFFECTIVE PSYCHOSIS; TWINS; ADOPTION; COPY NUMBER VARIATION; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; PSYCHOLOGY; PSYCHOSIS; SCHIZOPHRENIA;

EID: 84898929720     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbu016     Document Type: Article
Times cited : (199)

References (141)
  • 2
    • 84898962196 scopus 로고
    • Cutting J, Shepherd M, eds. The Clinical Roots of the Schizophrenia Concept. Cambridge, England: Cambridge University Press 1987
    • Kraepelin E. Dementia praecox (1896). In: Cutting J, Shepherd M, eds. The Clinical Roots of the Schizophrenia Concept. Cambridge, England: Cambridge University Press; 1987:13-24.
    • (1896) Dementia praecox , pp. 13-24
    • Kraepelin, E.1
  • 3
    • 18644386195 scopus 로고    scopus 로고
    • The beginning of the end for the Kraepelinian dichotomy
    • Craddock N, Owen MJ. The beginning of the end for the Kraepelinian dichotomy. Br J Psychiatry. 2005;186:364-366.
    • (2005) Br J Psychiatry. , vol.186 , pp. 364-366
    • Craddock, N.1    Owen, M.J.2
  • 4
    • 76749157485 scopus 로고    scopus 로고
    • The Kraepelinian dichotomy-going, going. but still not gone
    • Craddock N, Owen MJ. The Kraepelinian dichotomy-going, going. but still not gone. Br J Psychiatry. 2010;196:92-95.
    • (2010) Br J Psychiatry. , vol.196 , pp. 92-95
    • Craddock, N.1    Owen, M.J.2
  • 6
    • 0003472502 scopus 로고    scopus 로고
    • American Psychiatric Association. 5th ed. Arlington, VA American Psychiatric Association
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Arlington, VA: American Psychiatric Association; 2013.
    • (2013) Diagnostic and Statistical Manual of Mental Disorders
  • 7
    • 4944240955 scopus 로고    scopus 로고
    • A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder
    • Murray RM, Sham P, Van Os J, Zanelli J, Cannon M, McDonald C. A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophr Res. 2004;71:405-416.
    • (2004) Schizophr Res. , vol.71 , pp. 405-416
    • Murray, R.M.1    Sham, P.2    Van Os, J.3    Zanelli, J.4    Cannon, M.5    McDonald, C.6
  • 9
    • 39949083194 scopus 로고    scopus 로고
    • Schizophrenia Just the Facts what we know in 2008 part 1: Overview
    • Tandon R, Keshavan MS, Nasrallah HA. Schizophrenia, 'Just the Facts': What we know in 2008 part 1: Overview. Schizophr Res. 2008;100:4-19.
    • (2008) Schizophr Res. , vol.100 , pp. 4-19
    • Tandon, R.1    Keshavan, M.S.2    Nasrallah, H.A.3
  • 10
    • 0033040141 scopus 로고    scopus 로고
    • Heritability estimates for psychotic disorders: The Maudsley twin psychosis series
    • Cardno AG, Marshall EJ, Coid B, et al. Heritability estimates for psychotic disorders: The Maudsley twin psychosis series. Arch Gen Psychiatry. 1999;56:162-168.
    • (1999) Arch Gen Psychiatry. , vol.56 , pp. 162-168
    • Cardno, A.G.1    Marshall, E.J.2    Coid, B.3
  • 11
    • 33745985710 scopus 로고    scopus 로고
    • Genetics and delusional disorder
    • Cardno AG, McGuffin P. Genetics and delusional disorder. Behav Sci Law. 2006;24:257-276.
    • (2006) Behav Sci Law. , vol.24 , pp. 257-276
    • Cardno, A.G.1    McGuffin, P.2
  • 14
    • 58149464318 scopus 로고    scopus 로고
    • Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study
    • Lichtenstein P, Yip BH, Björk C, et al. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study. Lancet. 2009;373:234-239.
    • (2009) Lancet. , vol.373 , pp. 234-239
    • Lichtenstein, P.1    Yip, B.H.2    Björk, C.3
  • 15
    • 0020984882 scopus 로고
    • The nosology of schizoaffective psychosis
    • Brockington IF, Meltzer HY. The nosology of schizoaffective psychosis. Psychiatr Dev. 1983;1:317-338.
    • (1983) Psychiatr Dev. , vol.1 , pp. 317-338
    • Brockington, I.F.1    Meltzer, H.Y.2
  • 16
    • 84898967994 scopus 로고
    • In Kendell RE, Zeally AK, eds. Companion to Psychiatric Studies. 4th ed. Edinburgh, UK: Churchill Livingstone
    • Kendell RE. Other functional psychoses. In: Kendell RE, Zeally AK, eds. Companion to Psychiatric Studies. 4th ed. Edinburgh, UK: Churchill Livingstone; 1988:362-373.
    • (1988) Other functional psychoses , pp. 362-373
    • Kendell, R.E.1
  • 17
    • 0028966225 scopus 로고
    • Schizoaffective psychoses: Genetical clues to classification
    • Bertelsen A, Gottesman II. Schizoaffective psychoses: Genetical clues to classification. Am J Med Genet. 1995;60:7-11.
    • (1995) Am J Med Genet. , vol.60 , pp. 7-11
    • Bertelsen, A.1    Gottesman, I.I.2
  • 18
    • 0028961279 scopus 로고
    • Examining the validity of DSM-III-R schizoaffective disorder and its putative subtypes in the Roscommon Family Study
    • Kendler KS, McGuire M, Gruenberg AM, Walsh D. Examining the validity of DSM-III-R schizoaffective disorder and its putative subtypes in the Roscommon Family Study. Am J Psychiatry. 1995;152:755-764.
    • (1995) Am J Psychiatry. , vol.152 , pp. 755-764
    • Kendler, K.S.1    McGuire, M.2    Gruenberg, A.M.3    Walsh, D.4
  • 19
    • 38149114172 scopus 로고    scopus 로고
    • Does schizoaffective disorder really exist? A systematic review of the studies that compared schizoaffective disorder with schizophrenia or mood disorders
    • Cheniaux E, Landeira-Fernandez J, Lessa Telles L, et al. Does schizoaffective disorder really exist? A systematic review of the studies that compared schizoaffective disorder with schizophrenia or mood disorders. J Affect Disord. 2008;106:209-217.
    • (2008) J Affect Disord. , vol.106 , pp. 209-217
    • Cheniaux, E.1    Landeira-Fernandez, J.2    Lessa Telles, L.3
  • 20
    • 65349168411 scopus 로고    scopus 로고
    • Psychosis genetics: Modeling the relationship between schizophrenia, bipolar disorder, and mixed (or 'schizoaffective') psychoses
    • Craddock N, O'Donovan MC, Owen MJ. Psychosis genetics: Modeling the relationship between schizophrenia, bipolar disorder, and mixed (or 'schizoaffective') psychoses. Schizophr Bull. 2009;35:482-490.
    • (2009) Schizophr Bull. , vol.35 , pp. 482-490
    • Craddock, N.1    O'Donovan, M.C.2    Owen, M.J.3
  • 21
    • 84855850253 scopus 로고    scopus 로고
    • A twin study of schizoaffective-mania, schizoaffective-depression, and other psychotic syndromes
    • Cardno AG, Rijsdijk FV, West RM, et al. A twin study of schizoaffective-mania, schizoaffective-depression, and other psychotic syndromes. Am J Med Genet B Neuropsychiatr Genet. 2012;159B:172-182.
    • (2012) Am J Med Genet B Neuropsychiatr Genet. , pp. 172-182
    • Cardno, A.G.1    Rijsdijk, F.V.2    West, R.M.3
  • 22
    • 84890100453 scopus 로고    scopus 로고
    • Boundaries of schizoaffective disorder: Revisiting Kraepelin
    • Kotov R, Leong SH, Mojtabai R, et al. Boundaries of schizoaffective disorder: Revisiting Kraepelin. JAMA Psychiatry. 2013;70:1276-1286.
    • (2013) JAMA Psychiatry. , vol.70 , pp. 1276-1286
    • Kotov, R.1    Leong, S.H.2    Mojtabai, R.3
  • 23
    • 0034598424 scopus 로고    scopus 로고
    • Reliability and validity of the DSM-IV diagnostic category of schizoaffective disorder: Preliminary data
    • Maj M, Pirozzi R, Formicola AM, Bartoli L, Bucci P. Reliability and validity of the DSM-IV diagnostic category of schizoaffective disorder: Preliminary data. J Affect Disord. 2000;57:95-98.
    • (2000) J Affect Disord. , vol.57 , pp. 95-98
    • Maj, M.1    Pirozzi, R.2    Formicola, A.M.3    Bartoli, L.4    Bucci, P.5
  • 24
    • 84862777570 scopus 로고    scopus 로고
    • Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes
    • Wray NR, Lee SH, Kendler KS. Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes. Eur J Hum Genet. 2012;20:668-674.
    • (2012) Eur J Hum Genet. , vol.20 , pp. 668-674
    • Wray, N.R.1    Lee, S.H.2    Kendler, K.S.3
  • 25
    • 0034085204 scopus 로고    scopus 로고
    • Congruence of diagnoses 2 years after a first-Admission diagnosis of psychosis
    • Schwartz JE, Fennig S, Tanenberg-Karant M, et al. Congruence of diagnoses 2 years after a first-Admission diagnosis of psychosis. Arch Gen Psychiatry. 2000;57:593-600.
    • (2000) Arch Gen Psychiatry. , vol.57 , pp. 593-600
    • Schwartz, J.E.1    Fennig, S.2    Tanenberg-Karant, M.3
  • 26
    • 23744513351 scopus 로고    scopus 로고
    • Family history of psychiatric illness as a risk factor for schizoaffective disorder: A Danish registerbased cohort study
    • Laursen TM, Labouriau R, Licht RW, Bertelsen A, Munk-Olsen T, Mortensen PB. Family history of psychiatric illness as a risk factor for schizoaffective disorder: A Danish registerbased cohort study. Arch Gen Psychiatry. 2005;62:841-848.
    • (2005) Arch Gen Psychiatry. , vol.62 , pp. 841-848
    • Laursen, T.M.1    Labouriau, R.2    Licht, R.W.3    Bertelsen, A.4    Munk-Olsen, T.5    Mortensen, P.B.6
  • 28
    • 0027216273 scopus 로고
    • The genetics of schizophrenia: A current, genetic-epidemiologic perspective
    • Kendler KS, Diehl SR. The genetics of schizophrenia: A current, genetic-epidemiologic perspective. Schizophr Bull. 1993;19:261-285.
    • (1993) Schizophr Bull. , vol.19 , pp. 261-285
    • Kendler, K.S.1    Diehl, S.R.2
  • 31
    • 0016652377 scopus 로고
    • Transmitted factors in the morbid risk of affective disorders: A controlled study
    • Gershon ES, Amalia M, Cohen N, et al. Transmitted factors in the morbid risk of affective disorders: A controlled study. J Psychiatr Res. 1975;12:283-299.
    • (1975) J Psychiatr Res. , vol.12 , pp. 283-299
    • Gershon, E.S.1    Amalia, M.2    Cohen, N.3
  • 32
    • 0019975573 scopus 로고
    • A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands
    • Gershon ES, Hamovit J, Guroff JJ, et al. A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands. Arch Gen Psychiatry. 1982;39:1157-1167.
    • (1982) Arch Gen Psychiatry. , vol.39 , pp. 1157-1167
    • Gershon, E.S.1    Hamovit, J.2    Guroff, J.J.3
  • 33
    • 0019143717 scopus 로고
    • Morbidity risks of schizophrenia and affective disorders among first degree relatives of patients with schizophrenia, mania, depression and surgical conditions
    • Tsuang MT, Winokur G, Crowe RR. Morbidity risks of schizophrenia and affective disorders among first degree relatives of patients with schizophrenia, mania, depression and surgical conditions. Br J Psychiatry. 1980;137:497-504.
    • (1980) Br J Psychiatry. , vol.137 , pp. 497-504
    • Tsuang, M.T.1    Winokur, G.2    Crowe, R.R.3
  • 34
    • 0027432603 scopus 로고
    • Continuity and discontinuity of affective disorders and schizophrenia Results of a controlled family study
    • Maier W, Lichtermann D, Minges J, et al. Continuity and discontinuity of affective disorders and schizophrenia. Results of a controlled family study. Arch Gen Psychiatry. 1993;50:871-883.
    • (1993) Arch Gen Psychiatry. , vol.50 , pp. 871-883
    • Maier, W.1    Lichtermann, D.2    Minges, J.3
  • 35
    • 0022495601 scopus 로고
    • A DSM-III family study of the nonschizophrenic psychotic disorders
    • Kendler KS, Gruenberg AM, Tsuang MT. A DSM-III family study of the nonschizophrenic psychotic disorders. Am J Psychiatry. 1986;143:1098-1105.
    • (1986) Am J Psychiatry. , vol.143 , pp. 1098-1105
    • Kendler, K.S.1    Gruenberg, A.M.2    Tsuang, M.T.3
  • 36
  • 37
    • 76649104723 scopus 로고    scopus 로고
    • Psychiatric family history and schizophrenia risk in Denmark: Which mental disorders are relevant?
    • Mortensen PB, Pedersen MG, Pedersen CB. Psychiatric family history and schizophrenia risk in Denmark: Which mental disorders are relevant? Psychol Med. 2010;40:201-210.
    • (2010) Psychol Med. , vol.40 , pp. 201-210
    • Mortensen, P.B.1    Pedersen, M.G.2    Pedersen, C.B.3
  • 39
    • 0034060459 scopus 로고    scopus 로고
    • Twin studies of schizophrenia: From bow-And-Arrow concordances to star wars Mx and functional genomics
    • Cardno AG, Gottesman II. Twin studies of schizophrenia: From bow-And-Arrow concordances to star wars Mx and functional genomics. Am J Med Genet. 2000;97:12-17.
    • (2000) Am J Med Genet. , vol.97 , pp. 12-17
    • Cardno, A.G.1    Gottesman, I.I.2
  • 40
    • 0037629099 scopus 로고    scopus 로고
    • The heritability of bipolar affective disorder and the genetic relationship to unipolar depression
    • McGuffin P, Rijsdijk F, Andrew M, Sham P, Katz R, Cardno A. The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Arch Gen Psychiatry. 2003;60:497-502.
    • (2003) Arch Gen Psychiatry. , vol.60 , pp. 497-502
    • McGuffin, P.1    Rijsdijk, F.2    Andrew, M.3    Sham, P.4    Katz, R.5    Cardno, A.6
  • 42
    • 0013937338 scopus 로고
    • Psychiatric disorders in foster home reared children of schizophrenic mothers
    • Heston LL. Psychiatric disorders in foster home reared children of schizophrenic mothers. Br J Psychiatry. 1966;112:819-825.
    • (1966) Br J Psychiatry. , vol.112 , pp. 819-825
    • Heston, L.L.1
  • 44
    • 0028206470 scopus 로고
    • Mental illness in the biological and adoptive relatives of schizophrenic adoptees replication of the copenhagen study in the rest of denmark
    • Kety SS, Wender PH, Jacobsen B, et al. Mental illness in the biological and adoptive relatives of schizophrenic adoptees. Replication of the Copenhagen Study in the rest of Denmark. Arch Gen Psychiatry. 1994;51:442-455.
    • (1994) Arch Gen Psychiatry. , vol.51 , pp. 442-455
    • Kety, S.S.1    Wender, P.H.2    Jacobsen, B.3
  • 45
    • 0016015998 scopus 로고
    • Crossfostering A research strategy for clarifying the role of genetic and experiential factors in the etiology of schizophrenia
    • Wender PH, Rosenthal D, Kety SS, Schulsinger F, Welner J. Crossfostering. A research strategy for clarifying the role of genetic and experiential factors in the etiology of schizophrenia. Arch Gen Psychiatry. 1974;30:121-128.
    • (1974) Arch Gen Psychiatry. , vol.30 , pp. 121-128
    • Wender, P.H.1    Rosenthal, D.2    Kety, S.S.3    Schulsinger, F.4    Welner, J.5
  • 46
    • 0028341856 scopus 로고
    • Independent diagnoses of adoptees and relatives as defined by DSMIII in the provincial and national samples of the Danish Adoption Study of Schizophrenia
    • Kendler KS, Gruenberg AM, Kinney DK. Independent diagnoses of adoptees and relatives as defined by DSMIII in the provincial and national samples of the Danish Adoption Study of Schizophrenia. Arch Gen Psychiatry. 1994;51:456-468.
    • (1994) Arch Gen Psychiatry. , vol.51 , pp. 456-468
    • Kendler, K.S.1    Gruenberg, A.M.2    Kinney, D.K.3
  • 47
    • 0642282707 scopus 로고    scopus 로고
    • Genetic boundaries of the schizophrenia spectrum: Evidence from the finnish adoptive family study of schizophrenia
    • Tienari P, Wynne LC, Läksy K, et al. Genetic boundaries of the schizophrenia spectrum: Evidence from the Finnish Adoptive Family Study of Schizophrenia. Am J Psychiatry. 2003;160:1587-1594.
    • (2003) Am J Psychiatry. , vol.160 , pp. 1587-1594
    • Tienari, P.1    Wynne, L.C.2    Läksy, K.3
  • 48
    • 0017642345 scopus 로고
    • Adoption study supporting genetic transmission in manic-depressive illness
    • Mendlewicz J, Rainer JD. Adoption study supporting genetic transmission in manic-depressive illness. Nature. 1977;268:327-329.
    • (1977) Nature. , vol.268 , pp. 327-329
    • Mendlewicz, J.1    Rainer, J.D.2
  • 49
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a complex trait: Evidence from a meta-Analysis of twin studies
    • Sullivan PF, Kendler KS, Neale MC. Schizophrenia as a complex trait: Evidence from a meta-Analysis of twin studies. Arch Gen Psychiatry. 2003;60:1187-1192.
    • (2003) Arch Gen Psychiatry. , vol.60 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 50
    • 84869025817 scopus 로고    scopus 로고
    • Using summary data from the Danish national registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder
    • Wray NR, Gottesman II. Using summary data from the Danish national registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder. Front Genet. 2012;3:118.
    • (2012) Front Genet. , vol.3 , pp. 118
    • Wray, N.R.1    Gottesman, I.I.2
  • 51
  • 52
    • 0025019555 scopus 로고
    • Linkage strategies for genetically complex traits I Multilocus models
    • Risch N. Linkage strategies for genetically complex traits I Multilocus models. Am J Hum Genet. 1990;46:222-228.
    • (1990) Am J Hum Genet. , vol.46 , pp. 222-228
    • Risch, N.1
  • 53
  • 54
    • 0029168042 scopus 로고
    • Mathematical limits of multilocus models: The genetic transmission of bipolar disorder
    • Craddock N, Khodel V, Van Eerdewegh P, Reich T. Mathematical limits of multilocus models: The genetic transmission of bipolar disorder. Am J Hum Genet. 1995;57:690-702.
    • (1995) Am J Hum Genet. , vol.57 , pp. 690-702
    • Craddock, N.1    Khodel, V.2    Van Eerdewegh, P.3    Reich, T.4
  • 55
    • 0023875083 scopus 로고
    • A controlled family study of chronic psychoses Schizophrenia and schizoaffective disorder
    • Gershon ES, DeLisi LE, Hamovit J, et al. A controlled family study of chronic psychoses. Schizophrenia and schizoaffective disorder. Arch Gen Psychiatry. 1988;45:328-336.
    • (1988) Arch Gen Psychiatry. , vol.45 , pp. 328-336
    • Gershon, E.S.1    DeLisi, L.E.2    Hamovit, J.3
  • 57
    • 0002616202 scopus 로고    scopus 로고
    • The common genetic liability between schizophrenia and bipolar disorder: A review
    • Bramon E, Sham PC. The common genetic liability between schizophrenia and bipolar disorder: A review. Curr Psychiatry Rep. 2001;3:332-337.
    • (2001) Curr Psychiatry Rep. , vol.3 , pp. 332-337
    • Bramon, E.1    Sham, P.C.2
  • 58
    • 67650456775 scopus 로고    scopus 로고
    • Meta-Analytic evidence for familial coaggregation of schizophrenia and bipolar disorder
    • Van Snellenberg JX, de Candia T. Meta-Analytic evidence for familial coaggregation of schizophrenia and bipolar disorder. Arch Gen Psychiatry. 2009;66:748-755.
    • (2009) Arch Gen Psychiatry. , vol.66 , pp. 748-755
    • Van Snellenberg, J.X.1    De Candia, T.2
  • 61
    • 15044363048 scopus 로고    scopus 로고
    • The genetics of schizophrenia and bipolar disorder: Dissecting psychosis
    • Craddock N, O'Donovan MC, Owen MJ. The genetics of schizophrenia and bipolar disorder: Dissecting psychosis. J Med Genet. 2005;42:193-204.
    • (2005) J Med Genet. , vol.42 , pp. 193-204
    • Craddock, N.1    O'Donovan, M.C.2    Owen, M.J.3
  • 62
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • Ripke S, Sanders A, Kendler KS, et al. Genome-wide association study identifies five new schizophrenia loci. Nat Genet. 2011;43:969-976.
    • (2011) Nat Genet. , vol.43 , pp. 969-976
    • Ripke, S.1    Sanders, A.2    Kendler, K.S.3
  • 63
    • 84885020424 scopus 로고    scopus 로고
    • Multicenter genetic studies of schizophrenia consortium; psychosis endophenotypes international consortium; wellcome trust case control consortium 2 genome-wide association analysis identifies 13 new risk loci for schizophrenia
    • Ripke S, O'Dushlaine C, Chambert K, et al.; Multicenter Genetic Studies of Schizophrenia Consortium; Psychosis Endophenotypes International Consortium; Wellcome Trust Case Control Consortium 2. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet. 2013;45:1150-1159.
    • (2013) Nat Genet. , vol.45 , pp. 1150-1159
    • Ripke, S.1    O'Dushlaine, C.2    Chambert, K.3
  • 64
    • 80053385384 scopus 로고    scopus 로고
    • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
    • Sklar P, Ripke S, Scott LJ, et al. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet. 2011;43:977-983.
    • (2011) Nat Genet. , vol.43 , pp. 977-983
    • Sklar, P.1    Ripke, S.2    Scott, L.J.3
  • 65
    • 50449100461 scopus 로고    scopus 로고
    • Molecular genetics of schizophrenia collaboration identification of loci associated with schizophrenia by genome-wide association and follow-up
    • O'Donovan MC, Craddock N, Norton N, et al.; Molecular Genetics of Schizophrenia Collaboration. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet. 2008;40:1053-1055.
    • (2008) Nat Genet. , vol.40 , pp. 1053-1055
    • O'Donovan, M.C.1    Craddock, N.2    Norton, N.3
  • 66
    • 79953034507 scopus 로고    scopus 로고
    • Molecular genetics of schizophrenia collaboration (mgs) international schizophrenia consortium (isc), sgene-plus, group fine mapping of znf804a and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder
    • Williams HJ, Norton N, Dwyer S, et al.; Molecular Genetics of Schizophrenia Collaboration (MGS) International Schizophrenia Consortium (ISC), SGENE-plus, GROUP. Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Mol Psychiatry. 2011;16:429-441.
    • (2011) Mol Psychiatry. , vol.16 , pp. 429-441
    • Williams, H.J.1    Norton, N.2    Dwyer, S.3
  • 67
    • 68449096727 scopus 로고    scopus 로고
    • Common variants on chromosome 6p22.1 are associated with schizophrenia
    • Shi J, Levinson DF, Duan J, et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature. 2009;460:753-757.
    • (2009) Nature. , vol.460 , pp. 753-757
    • Shi, J.1    Levinson, D.F.2    Duan, J.3
  • 68
    • 68449090594 scopus 로고    scopus 로고
    • Genetic risk and outcome in psychosis (group) common variants conferring risk of schizophrenia
    • Stefansson H, Ophoff RA, Steinberg S, et al.; Genetic Risk and Outcome in Psychosis (GROUP). Common variants conferring risk of schizophrenia. Nature. 2009;460:744-747.
    • (2009) Nature. , vol.460 , pp. 744-747
    • Stefansson, H.1    Ophoff, R.A.2    Steinberg, S.3
  • 69
    • 50449089356 scopus 로고    scopus 로고
    • Wellcome trust case control consortium collaborative genome-wide association analysis supports a role for ank3 and cacna1c in bipolar disorder
    • Ferreira MA, O'Donovan MC, Meng YA, et al.; Wellcome Trust Case Control Consortium. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet. 2008;40:1056-1058.
    • (2008) Nat Genet. , vol.40 , pp. 1056-1058
    • Ferreira, M.A.1    O'Donovan, M.C.2    Meng, Y.A.3
  • 70
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: The emerging picture and its implications
    • Sullivan PF, Daly MJ, O'Donovan M. Genetic architectures of psychiatric disorders: The emerging picture and its implications. Nat Rev Genet. 2012;13:537-551.
    • (2012) Nat Rev Genet. , vol.13 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O'Donovan, M.3
  • 71
    • 60549085927 scopus 로고    scopus 로고
    • Wellcome trust case control consortium gene-wide analyses of genomewide association data sets: Evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk
    • Moskvina V, Craddock N, Holmans P, et al.; Wellcome Trust Case Control Consortium. Gene-wide analyses of genomewide association data sets: Evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Mol Psychiatry. 2009;14:252-260.
    • (2009) Mol Psychiatry. , vol.14 , pp. 252-260
    • Moskvina, V.1    Craddock, N.2    Holmans, P.3
  • 72
    • 84876847154 scopus 로고    scopus 로고
    • Tobacco and genetics consortium; bipolar disorder psychiatric genomics consortium; schizophrenia psychiatric genomics consortium all snps are not created equal: Genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated snps
    • Schork AJ, Thompson WK, Pham P, et al.; Tobacco and Genetics Consortium; Bipolar Disorder Psychiatric Genomics Consortium; Schizophrenia Psychiatric Genomics Consortium. All SNPs are not created equal: Genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. PLoS Genet. 2013;9:e1003449.
    • (2013) PLoS Genet. , vol.9
    • Schork, A.J.1    Thompson, W.K.2    Pham, P.3
  • 73
    • 84876296688 scopus 로고    scopus 로고
    • Cross-disorder group of the psychiatric genomics consortium identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
    • Cross-Disorder Group of the Psychiatric Genomics Consortium. Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis. Lancet. 2013;381:1371-1379.
    • (2013) Lancet. , vol.381 , pp. 1371-1379
  • 74
    • 84878220679 scopus 로고    scopus 로고
    • Schizophrenia psychiatric genome-wide association study consortium; wellcome trust case control consortium+; wellcome trust case control consortium 2 genome-wide significant associations in schizophrenia to itih3/4, cacna1c and sdccag8, and extensive replication of associations reported by the schizophrenia pgc
    • Hamshere ML, Walters JT, Smith R, et al.; Schizophrenia Psychiatric Genome-wide Association Study Consortium; Wellcome Trust Case Control Consortium+; Wellcome Trust Case Control Consortium 2. Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Mol Psychiatry. 2013;18:708-712.
    • (2013) Mol Psychiatry. , vol.18 , pp. 708-712
    • Hamshere, M.L.1    Walters, J.T.2    Smith, R.3
  • 75
    • 84888296163 scopus 로고    scopus 로고
    • WTCCC Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample
    • Green EK, Hamshere M, Forty L, et al.; WTCCC. Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample. Mol Psychiatry. 2013;18:1302-1307.
    • (2013) Mol Psychiatry. , vol.18 , pp. 1302-1307
    • Green, E.K.1    Hamshere, M.2    Forty, L.3
  • 76
    • 84896062209 scopus 로고    scopus 로고
    • GROUP; wellcome trust case control consortium 2 common variant at 16p11.2 conferring risk of psychosis
    • Steinberg S, de Jong S, Mattheisen M, et al.; GROUP; Wellcome Trust Case Control Consortium 2. Common variant at 16p11.2 conferring risk of psychosis. Mol Psychiatry. 2014;19:108-114.
    • (2014) Mol Psychiatry. , vol.19 , pp. 108-114
    • Steinberg, S.1    De Jong, S.2    Mattheisen, M.3
  • 77
    • 84928650714 scopus 로고    scopus 로고
    • Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia. [published online ahead of print November 26, 2013]
    • doi:10.1038/mp.2013.138
    • Ruderfer DM, Fanous AH, Ripke S, et al. Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia. [published online ahead of print November 26, 2013]. Mol Psychiatry. doi:10.1038/mp.2013. 138.
    • Mol Psychiatry
    • Ruderfer, D.M.1    Fanous, A.H.2    Ripke, S.3
  • 78
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia Consortium
    • International Schizophrenia Consortium, Purcell SM, Wray NR, Stone JL, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009;460:748-752.
    • (2009) Nature. , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3
  • 79
    • 84862777863 scopus 로고    scopus 로고
    • Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs
    • Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ); International Schizophrenia Consortium (ISC); Molecular Genetics of Schizophrenia Collaboration (MGS)
    • Lee SH, DeCandia TR, Ripke S, et al.; Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ); International Schizophrenia Consortium (ISC); Molecular Genetics of Schizophrenia Collaboration (MGS). Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs. Nat Genet. 2012;44:247-250.
    • (2012) Nat Genet. , vol.44 , pp. 247-250
    • Lee, S.H.1    DeCandia, T.R.2    Ripke, S.3
  • 80
    • 84876834541 scopus 로고    scopus 로고
    • Psychiatric genomics consortium (pgc); bipolar disorder and schizophrenia working groupsfeti improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
    • Andreassen OA, Thompson WK, Schork AJ, et al.; Psychiatric Genomics Consortium (PGC); Bipolar Disorder and Schizophrenia Working Groups. Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate. PLoS Genet. 2013;9:e1003455.
    • (2013) PLoS Genet. , vol.9
    • Andreassen, O.A.1    Thompson, W.K.2    Schork, A.J.3
  • 81
    • 84883465830 scopus 로고    scopus 로고
    • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
    • Cross-Disorder Group of the Psychiatric Genomics Consortium
    • Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee SH, Ripke S, Neale BM, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013;45:984-994.
    • (2013) Nat Genet. , vol.45 , pp. 984-994
    • Lee, S.H.1    Ripke, S.2    Neale, B.M.3
  • 83
    • 0032882849 scopus 로고    scopus 로고
    • High rates of schizophrenia in adults with velo-cardio-facial syndrome
    • Murphy KC, Jones LA, Owen MJ. High rates of schizophrenia in adults with velo-cardio-facial syndrome. Arch Gen Psychiatry. 1999;56:940-945.
    • (1999) Arch Gen Psychiatry. , vol.56 , pp. 940-945
    • Murphy, K.C.1    Jones, L.A.2    Owen, M.J.3
  • 84
    • 3242808027 scopus 로고    scopus 로고
    • Large-scale copy number polymorphism in the human genome
    • Sebat J, Lakshmi B, Troge J, et al. Large-scale copy number polymorphism in the human genome. Science. 2004;305:525-528.
    • (2004) Science. , vol.305 , pp. 525-528
    • Sebat, J.1    Lakshmi, B.2    Troge, J.3
  • 85
    • 34347353237 scopus 로고    scopus 로고
    • Copy-number variation and association studies of human disease
    • McCarroll SA, Altshuler DM. Copy-number variation and association studies of human disease. Nat Genet. 2007;39:S37-S42.
    • (2007) Nat Genet. , vol.39
    • McCarroll, S.A.1    Altshuler, D.M.2
  • 86
    • 77949831756 scopus 로고    scopus 로고
    • Structural variation in the human genome and its role in disease
    • Stankiewicz P, Lupski JR. Structural variation in the human genome and its role in disease. Annu Rev Med. 2010;61:437-455.
    • (2010) Annu Rev Med. , vol.61 , pp. 437-455
    • Stankiewicz, P.1    Lupski, J.R.2
  • 87
    • 51649107017 scopus 로고    scopus 로고
    • International schizophrenia consortium rare chromosomal deletions and duplications increase risk of schizophrenia
    • Stone JL, O'Donovan MC, Gurling H, et al.; International Schizophrenia Consortium. Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature. 2008;455:237-241.
    • (2008) Nature. , vol.455 , pp. 237-241
    • Stone, J.L.1    O'Donovan, M.C.2    Gurling, H.3
  • 88
    • 42349088634 scopus 로고    scopus 로고
    • Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia
    • Walsh T, McClellan JM, McCarthy SE, et al. Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science. 2008;320:539-543.
    • (2008) Science. , vol.320 , pp. 539-543
    • Walsh, T.1    McClellan, J.M.2    McCarthy, S.E.3
  • 89
    • 49949085933 scopus 로고    scopus 로고
    • GROUP Large recurrent microdeletions associated with schizophrenia
    • Stefansson H, Rujescu D, Cichon S, et al.; GROUP. Large recurrent microdeletions associated with schizophrenia. Nature. 2008;455:232-236.
    • (2008) Nature. , vol.455 , pp. 232-236
    • Stefansson, H.1    Rujescu, D.2    Cichon, S.3
  • 90
    • 79952710338 scopus 로고    scopus 로고
    • Copy number variants in schizophrenia: Confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications
    • Levinson DF, Duan J, Oh S, et al. Copy number variants in schizophrenia: Confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. Am J Psychiatry. 2011;168:302-316.
    • (2011) Am J Psychiatry. , vol.168 , pp. 302-316
    • Levinson, D.F.1    Duan, J.2    Oh, S.3
  • 93
    • 84893611579 scopus 로고    scopus 로고
    • Analysis of copy number variations at 15 schizophrenia-Associated loci
    • Rees E, Walters JT, Georgieva L, et al. Analysis of copy number variations at 15 schizophrenia-Associated loci. Br J Psychiatry. 2014;204:108-114.
    • (2014) Br J Psychiatry. , vol.204 , pp. 108-114
    • Rees, E.1    Walters, J.T.2    Georgieva, L.3
  • 94
    • 58949088309 scopus 로고    scopus 로고
    • Contact in the genetics of autism and schizophrenia
    • Burbach JP, van der Zwaag B. Contact in the genetics of autism and schizophrenia. Trends Neurosci. 2009;32:69-72.
    • (2009) Trends Neurosci. , vol.32 , pp. 69-72
    • Burbach, J.P.1    Van Der Zwaag, B.2
  • 96
    • 78049303903 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: A genome-wide analysis
    • Williams NM, Zaharieva I, Martin A, et al. Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: A genome-wide analysis. Lancet. 2010;376:1401-1408.
    • (2010) Lancet. , vol.376 , pp. 1401-1408
    • Williams, N.M.1    Zaharieva, I.2    Martin, A.3
  • 97
    • 84893491567 scopus 로고    scopus 로고
    • The penetrance of copy number variations for schizophrenia and developmental delay
    • Kirov G, Rees E, Walters JT, et al. The penetrance of copy number variations for schizophrenia and developmental delay. Biol Psychiatry. 2014;75:378-385.
    • (2014) Biol Psychiatry. , vol.75 , pp. 378-385
    • Kirov, G.1    Rees, E.2    Walters, J.T.3
  • 98
    • 81855178259 scopus 로고    scopus 로고
    • De novo rates and selection of schizophrenia-Associated copy number variants
    • Rees E, Moskvina V, Owen MJ, O'Donovan MC, Kirov G. De novo rates and selection of schizophrenia-Associated copy number variants. Biol Psychiatry. 2011;70:1109-1114.
    • (2011) Biol Psychiatry. , vol.70 , pp. 1109-1114
    • Rees, E.1    Moskvina, V.2    Owen, M.J.3    O'Donovan, M.C.4    Kirov, G.5
  • 99
    • 77950587223 scopus 로고    scopus 로고
    • Rare copy number variants: A point of rarity in genetic risk for bipolar disorder and schizophrenia
    • Wellcome Trust Case Control Consortium
    • Grozeva D, Kirov G, Ivanov D, et al.; Wellcome Trust Case Control Consortium. Rare copy number variants: A point of rarity in genetic risk for bipolar disorder and schizophrenia. Arch Gen Psychiatry. 2010;67:318-327.
    • (2010) Arch Gen Psychiatry. , vol.67 , pp. 318-327
    • Grozeva, D.1    Kirov, G.2    Ivanov, D.3
  • 100
    • 79955766457 scopus 로고    scopus 로고
    • Analysis of genetic deletions and duplications in the university college london bipolar disorder case control sample
    • McQuillin A, Bass N, Anjorin A, et al. Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample. Eur J Hum Genet. 2011;19:588-592.
    • (2011) Eur J Hum Genet. , vol.19 , pp. 588-592
    • McQuillin, A.1    Bass, N.2    Anjorin, A.3
  • 101
    • 84897092542 scopus 로고    scopus 로고
    • Reduced burden of very large and rare CNVs in bipolar affective disorder
    • Grozeva D, Kirov G, Conrad DF, et al. Reduced burden of very large and rare CNVs in bipolar affective disorder. Bipolar Disord. 2013;15:893-898.
    • (2013) Bipolar Disord. , vol.15 , pp. 893-898
    • Grozeva, D.1    Kirov, G.2    Conrad, D.F.3
  • 102
    • 84155191408 scopus 로고    scopus 로고
    • High frequencies of de novo CNVs in bipolar disorder and schizophrenia
    • Malhotra D, McCarthy S, Michaelson JJ, et al. High frequencies of de novo CNVs in bipolar disorder and schizophrenia. Neuron. 2011;72:951-963.
    • (2011) Neuron. , vol.72 , pp. 951-963
    • Malhotra, D.1    McCarthy, S.2    Michaelson, J.J.3
  • 103
    • 62849092230 scopus 로고    scopus 로고
    • Singleton deletions throughout the genome increase risk of bipolar disorder
    • Zhang D, Cheng L, Qian Y, et al. Singleton deletions throughout the genome increase risk of bipolar disorder. Mol Psychiatry. 2009;14:376-380.
    • (2009) Mol Psychiatry. , vol.14 , pp. 376-380
    • Zhang, D.1    Cheng, L.2    Qian, Y.3
  • 104
    • 84892620880 scopus 로고    scopus 로고
    • CNVs conferring risk of autism or schizophrenia affect cognition in controls
    • Stefansson H, Meyer-Lindenberg A, Steinberg S, et al. CNVs conferring risk of autism or schizophrenia affect cognition in controls. Nature. 2014;505:361-366.
    • (2014) Nature. , vol.505 , pp. 361-366
    • Stefansson, H.1    Meyer-Lindenberg, A.2    Steinberg, S.3
  • 105
    • 75649122572 scopus 로고    scopus 로고
    • Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype
    • Wellcome Trust Case Control Consortium (WTCCC)
    • Craddock N, Jones L, Jones IR, et al.; Wellcome Trust Case Control Consortium (WTCCC). Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype. Mol Psychiatry. 2010;15:146-153.
    • (2010) Mol Psychiatry. , vol.15 , pp. 146-153
    • Craddock, N.1    Jones, L.2    Jones, I.R.3
  • 106
    • 79957478245 scopus 로고    scopus 로고
    • Independent evidence for the selective influence of GABA(A) receptors on one component of the bipolar disorder phenotype
    • Breuer R, Hamshere ML, Strohmaier J, et al. Independent evidence for the selective influence of GABA(A) receptors on one component of the bipolar disorder phenotype. Mol Psychiatry. 2011;16:587-589.
    • (2011) Mol Psychiatry. , vol.16 , pp. 587-589
    • Breuer, R.1    Hamshere, M.L.2    Strohmaier, J.3
  • 108
    • 67650924855 scopus 로고    scopus 로고
    • Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept
    • Wellcome Trust Case Control Consortium
    • Hamshere ML, Green EK, Jones IR, et al.; Wellcome Trust Case Control Consortium. Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept. Br J Psychiatry. 2009;195:23-29.
    • (2009) Br J Psychiatry. , vol.195 , pp. 23-29
    • Hamshere, M.L.1    Green, E.K.2    Jones, I.R.3
  • 109
    • 84871829231 scopus 로고    scopus 로고
    • Schizophrenia psychiatric genome-wide association study (gwas) consortium genome-wide association study of clinical dimensions of schizophrenia: Polygenic effect on disorganized symptoms
    • Fanous AH, Zhou B, Aggen SH, et al.; Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. Genome-wide association study of clinical dimensions of schizophrenia: Polygenic effect on disorganized symptoms. Am J Psychiatry. 2012;169:1309-1317.
    • (2012) Am J Psychiatry. , vol.169 , pp. 1309-1317
    • Fanous, A.H.1    Zhou, B.2    Aggen, S.H.3
  • 110
    • 12444313073 scopus 로고    scopus 로고
    • Genetic heterogeneity, modifier genes, and quantitative phenotypes in psychiatric illness: Searching for a framework
    • Fanous AH, Kendler KS. Genetic heterogeneity, modifier genes, and quantitative phenotypes in psychiatric illness: Searching for a framework. Mol Psychiatry. 2005;10:6-13.
    • (2005) Mol Psychiatry. , vol.10 , pp. 6-13
    • Fanous, A.H.1    Kendler, K.S.2
  • 112
    • 84892659999 scopus 로고    scopus 로고
    • Boosting the power of schizophrenia genetics by leveraging new statistical tools
    • Andreassen OA, Thompson WK, Dale AM. Boosting the power of schizophrenia genetics by leveraging new statistical tools. Schizophr Bull. 2014;40:13-17.
    • (2014) Schizophr Bull. , vol.40 , pp. 13-17
    • Andreassen, O.A.1    Thompson, W.K.2    Dale, A.M.3
  • 113
    • 80052269336 scopus 로고    scopus 로고
    • Increased exonic de novo mutation rate in individuals with schizophrenia
    • Girard SL, Gauthier J, Noreau A, et al. Increased exonic de novo mutation rate in individuals with schizophrenia. Nat Genet. 2011;43:860-863.
    • (2011) Nat Genet. , vol.43 , pp. 860-863
    • Girard, S.L.1    Gauthier, J.2    Noreau, A.3
  • 114
    • 84870489243 scopus 로고    scopus 로고
    • De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia
    • Xu B, Ionita-Laza I, Roos JL, et al. De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia. Nat Genet. 2012;44:1365-1369.
    • (2012) Nat Genet. , vol.44 , pp. 1365-1369
    • Xu, B.1    Ionita-Laza, I.2    Roos, J.L.3
  • 115
    • 84864911042 scopus 로고    scopus 로고
    • Exome sequencing followed by large-scale genotyping suggests a limited role for moderately rare risk factors of strong effect in schizophrenia
    • Need AC, McEvoy JP, Gennarelli M, et al. Exome sequencing followed by large-scale genotyping suggests a limited role for moderately rare risk factors of strong effect in schizophrenia. Am J Hum Genet. 2012;91:303-312.
    • (2012) Am J Hum Genet. , vol.91 , pp. 303-312
    • Need, A.C.1    McEvoy, J.P.2    Gennarelli, M.3
  • 116
    • 84881193129 scopus 로고    scopus 로고
    • Consortium on the genetics of schizophrenia (cogs); paartners study group spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network
    • Gulsuner S, Walsh T, Watts AC, et al.; Consortium on the Genetics of Schizophrenia (COGS); PAARTNERS Study Group. Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network. Cell. 2013;154:518-529.
    • (2013) Cell. , vol.154 , pp. 518-529
    • Gulsuner, S.1    Walsh, T.2    Watts, A.C.3
  • 117
    • 49049110785 scopus 로고    scopus 로고
    • Gene expression in the etiology of schizophrenia
    • Bray NJ. Gene expression in the etiology of schizophrenia. Schizophr Bull. 2008;34:412-418.
    • (2008) Schizophr Bull. , vol.34 , pp. 412-418
    • Bray, N.J.1
  • 118
    • 34247619460 scopus 로고    scopus 로고
    • Behavioral phenotypes of Disc1 missense mutations in mice
    • Clapcote SJ, Lipina TV, Millar JK, et al. Behavioral phenotypes of Disc1 missense mutations in mice. Neuron. 2007;54:387-402.
    • (2007) Neuron. , vol.54 , pp. 387-402
    • Clapcote, S.J.1    Lipina, T.V.2    Millar, J.K.3
  • 119
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • Nestler EJ, Hyman SE. Animal models of neuropsychiatric disorders. Nat Neurosci. 2010;13:1161-1169.
    • (2010) Nat Neurosci. , vol.13 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 120
    • 84865845956 scopus 로고    scopus 로고
    • Studies in humans and mice implicate neurocan in the etiology of mania
    • Miró X, Meier S, Dreisow ML, et al. Studies in humans and mice implicate neurocan in the etiology of mania. Am J Psychiatry. 2012;169:982-990.
    • (2012) Am J Psychiatry. , vol.169 , pp. 982-990
    • Miró, X.1    Meier, S.2    Dreisow, M.L.3
  • 121
    • 84877704720 scopus 로고    scopus 로고
    • Genetics of bipolar disorder
    • Craddock N, Sklar P. Genetics of bipolar disorder. Lancet. 2013;381:1654-1662.
    • (2013) Lancet. , vol.381 , pp. 1654-1662
    • Craddock, N.1    Sklar, P.2
  • 122
    • 81855183787 scopus 로고    scopus 로고
    • Diseaseassociated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder
    • Dempster EL, Pidsley R, Schalkwyk LC, et al. Diseaseassociated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum Mol Genet. 2011;20:4786-4796.
    • (2011) Hum Mol Genet. , vol.20 , pp. 4786-4796
    • Dempster, E.L.1    Pidsley, R.2    Schalkwyk, L.C.3
  • 123
    • 0032583183 scopus 로고    scopus 로고
    • Dopamine receptor D2 Ser/Cys311 variant associated with disorganized symptomatology of schizophrenia
    • Serretti A, Macciardi F, Smeraldi E. Dopamine receptor D2 Ser/Cys311 variant associated with disorganized symptomatology of schizophrenia. Schizophr Res. 1998;34:207-210.
    • (1998) Schizophr Res. , vol.34 , pp. 207-210
    • Serretti, A.1    Macciardi, F.2    Smeraldi, E.3
  • 125
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman II, Gould TD. The endophenotype concept in psychiatry: Etymology and strategic intentions. Am J Psychiatry. 2003;160:636-645.
    • (2003) Am J Psychiatry. , vol.160 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 126
    • 65549147665 scopus 로고    scopus 로고
    • Neural mechanisms of a genome-wide supported psychosis variant
    • Esslinger C, Walter H, Kirsch P, et al. Neural mechanisms of a genome-wide supported psychosis variant. Science. 2009;324:605.
    • (2009) Science. , vol.324 , pp. 605
    • Esslinger, C.1    Walter, H.2    Kirsch, P.3
  • 127
    • 77954485170 scopus 로고    scopus 로고
    • Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia
    • Walters JT, Corvin A, Owen MJ, et al. Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia. Arch Gen Psychiatry. 2010;67:692-700.
    • (2010) Arch Gen Psychiatry. , vol.67 , pp. 692-700
    • Walters, J.T.1    Corvin, A.2    Owen, M.J.3
  • 128
    • 83055160768 scopus 로고    scopus 로고
    • Altered cortical network dynamics: A potential intermediate phenotype for schizophrenia and association with ZNF804A
    • Rasetti R, Sambataro F, Chen Q, Callicott JH, Mattay VS, Weinberger DR. Altered cortical network dynamics: A potential intermediate phenotype for schizophrenia and association with ZNF804A. Arch Gen Psychiatry. 2011;68:1207-1217.
    • (2011) Arch Gen Psychiatry. , vol.68 , pp. 1207-1217
    • Rasetti, R.1    Sambataro, F.2    Chen, Q.3    Callicott, J.H.4    Mattay, V.S.5    Weinberger, D.R.6
  • 129
    • 80051953863 scopus 로고    scopus 로고
    • Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia
    • Greenwood TA, Lazzeroni LC, Murray SS, et al. Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry. 2011;168:930-946.
    • (2011) Am J Psychiatry. , vol.168 , pp. 930-946
    • Greenwood, T.A.1    Lazzeroni, L.C.2    Murray, S.S.3
  • 130
    • 84887421193 scopus 로고    scopus 로고
    • Neuropsychological impairments in schizophrenia and psychotic bipolar disorder: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study
    • Hill SK, Reilly JL, Keefe RS, et al. Neuropsychological impairments in schizophrenia and psychotic bipolar disorder: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study. Am J Psychiatry. 2013;170:1275-1284.
    • (2013) Am J Psychiatry. , vol.170 , pp. 1275-1284
    • Hill, S.K.1    Reilly, J.L.2    Keefe, R.S.3
  • 131
    • 84883366833 scopus 로고    scopus 로고
    • Diffusion tensor imaging white matter endophenotypes in patients with schizophrenia or psychotic bipolar disorder and their relatives
    • Skudlarski P, Schretlen DJ, Thaker GK, et al. Diffusion tensor imaging white matter endophenotypes in patients with schizophrenia or psychotic bipolar disorder and their relatives. Am J Psychiatry. 2013;170:886-898.
    • (2013) Am J Psychiatry. , vol.170 , pp. 886-898
    • Skudlarski, P.1    Schretlen, D.J.2    Thaker, G.K.3
  • 133
    • 58149456676 scopus 로고    scopus 로고
    • Diagnosis of functional psychoses: Time to face the future
    • Owen MJ, Craddock N. Diagnosis of functional psychoses: Time to face the future. Lancet. 2009;373:190-191.
    • (2009) Lancet. , vol.373 , pp. 190-191
    • Owen, M.J.1    Craddock, N.2
  • 134
    • 84866657557 scopus 로고    scopus 로고
    • Implications of genetic findings for understanding schizophrenia
    • Owen MJ. Implications of genetic findings for understanding schizophrenia. Schizophr Bull. 2012;38:904-907.
    • (2012) Schizophr Bull. , vol.38 , pp. 904-907
    • Owen, M.J.1
  • 135
    • 84877626914 scopus 로고    scopus 로고
    • Toward the future of psychiatric diagnosis: The seven pillars of RDoC
    • Cuthbert BN, Insel TR. Toward the future of psychiatric diagnosis: The seven pillars of RDoC. BMC Med. 2013;11:126.
    • (2013) BMC Med. , vol.11 , pp. 126
    • Cuthbert, B.N.1    Insel, T.R.2
  • 136
    • 79958289097 scopus 로고    scopus 로고
    • Investigation of shared genetic effects for psychotic and obsessive symptoms in young adult twins
    • Fagnani C, Bellani M, Tansella M, et al. Investigation of shared genetic effects for psychotic and obsessive symptoms in young adult twins. Psychiatry Res. 2011;188:276-282.
    • (2011) Psychiatry Res. , vol.188 , pp. 276-282
    • Fagnani, C.1    Bellani, M.2    Tansella, M.3
  • 137
    • 33947232120 scopus 로고    scopus 로고
    • Genetic and environmental influences on schizotypy among adolescents in Taiwan: A multivariate twin/sibling analysis
    • Lin CC, Su CH, Kuo PH, Hsiao CK, Soong WT, Chen WJ. Genetic and environmental influences on schizotypy among adolescents in Taiwan: A multivariate twin/sibling analysis. Behav Genet. 2007;37:334-344.
    • (2007) Behav Genet. , vol.37 , pp. 334-344
    • Lin, C.C.1    Su, C.H.2    Kuo, P.H.3    Hsiao, C.K.4    Soong, W.T.5    Chen, W.J.6
  • 139
    • 64849096860 scopus 로고    scopus 로고
    • A systematic review and meta-Analysis of the psychosis continuum evidence for a psychosis pronenesspersistence-impairment model of psychotic disorder
    • van Os J, Linscott RJ, Myin-Germeys I, Delespaul P, Krabbendam L. A systematic review and meta-Analysis of the psychosis continuum: Evidence for a psychosis pronenesspersistence-impairment model of psychotic disorder. Psychol Med. 2009;39:179-195.
    • (2009) Psychol Med. , vol.39 , pp. 179-195
    • Van Os, J.1    Linscott, R.J.2    Myin-Germeys, I.3    Delespaul, P.4    Krabbendam, L.5
  • 140
    • 84899529792 scopus 로고    scopus 로고
    • Characterization of psychotic experiences in adolescence using the specific psychotic experiences questionnaire: Findings from a study of 5000 16-year-old twins 2013 [published online ahead of print September 23
    • doi:10.1093/schbul/sbt106
    • Ronald A, Sieradzka D, Cardno AG, Haworth CM, McGuire P, Freeman D. Characterization of psychotic experiences in adolescence using the specific psychotic experiences questionnaire: Findings from a study of 5000 16-year-old twins. [published online ahead of print September 23, 2013]. Schizophr Bull. doi:10.1093/schbul/sbt106.
    • Schizophr Bull
    • Ronald, A.1    Sieradzka, D.2    Cardno, A.G.3    Haworth, C.M.4    McGuire, P.5    Freeman, D.6
  • 141
    • 79952388633 scopus 로고    scopus 로고
    • Is there a schizophrenia to diagnosé
    • Owen MJ. Is there a schizophrenia to diagnosé World Psychiatry. 2011;10:34-35.
    • (2011) World Psychiatry. , vol.10 , pp. 34-35
    • Owen, M.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.