FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1

Journal of Digestive Diseases

Volumn 15, Issue 5, 2014, Pages 246-259

  Xing, Ying ^a,c   Wang, Zhi Hong ^b   Ma, Dong Hong ^b   Han, Ying ^b  

^a MEDICAL SCHOOL OF CHINESE PLA   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c 98th Hospital of Nanjing Military Command   (China)

Author keywords

Apoptosis; Chemotherapy; FTY720; Multidrug resistance; Multidrug resistance protein 1; P glycoprotein

Indexed keywords

DOXORUBICIN; ETOPOSIDE; FINGOLIMOD; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; ABCB1 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIBIOTIC; IMMUNOSUPPRESSIVE AGENT; PROPANEDIOL DERIVATIVE; SPHINGOSINE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CELL GROWTH; CELL VIABILITY; CELLULAR DISTRIBUTION; CHEMOSENSITIVITY; COLON CANCER; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; ADJUVANT CHEMOTHERAPY; ANALOGS AND DERIVATIVES; CELL SURVIVAL; COLON TUMOR; DRUG EFFECTS; DRUG RESISTANCE; GENETICS; METABOLISM; PATHOLOGY; PROCEDURES; TUMOR CELL LINE;

ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CHEMOTHERAPY, ADJUVANT; COLONIC NEOPLASMS; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; ETOPOSIDE; GENE EXPRESSION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; P-GLYCOPROTEIN; P-GLYCOPROTEINS; PROPYLENE GLYCOLS; SPHINGOSINE;

EID: 84898926856     PISSN: 17512972     EISSN: 17512980     Source Type: Journal    
DOI: 10.1111/1751-2980.12131     Document Type: Article

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