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Volumn 101, Issue 3, 1998, Pages 703-710

A multidrug-resistance protein (MRP)-like transmembrane pump is highly expressed by resting murine T helper (Th) 2, but not Th1 cells, and is induced to equal expression levels in Th1 and Th2 cells after antigenic stimulation in vivo

Author keywords

Leishmaniasis; Multidrug resistance protein; T helper 1; T helper 2

Indexed keywords

ANIMAL CELL; ANION TRANSPORT; ANTIGEN EXPRESSION; ARTICLE; CELL MEMBRANE TRANSPORT; HELPER CELL; LEISHMANIASIS; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0032006574     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI824     Document Type: Article
Times cited : (34)

References (40)
  • 1
    • 0021895138 scopus 로고
    • A new generation of Ca2+ indicators with greatly improved fluorescence properties
    • Grynkiewicz, G., M. Poenie, and R.Y. Tsien. 1985. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260:3440-3450.
    • (1985) J. Biol. Chem. , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 2
    • 0023848921 scopus 로고
    • Fura-2 secretion and sequestration in macrophages. a blocker of organic anion transport reveals that these processes occur via a membrane transport system for organic anions
    • Di Virgilio, F., T.H. Steinberg, J.A. Swanson, and S.C. Silverstein. 1988. Fura-2 secretion and sequestration in macrophages. A blocker of organic anion transport reveals that these processes occur via a membrane transport system for organic anions. J. Immunol. 140:915-920.
    • (1988) J. Immunol. , vol.140 , pp. 915-920
    • Di Virgilio, F.1    Steinberg, T.H.2    Swanson, J.A.3    Silverstein, S.C.4
  • 3
    • 0027938204 scopus 로고
    • Demonstration of organic anion transport in T lymphocytes. L-lactate and fluo-3 are target molecules
    • Sommer, F., S. Bischof, M. Rollinghoff, and M. Lohoff. 1994. Demonstration of organic anion transport in T lymphocytes. L-lactate and fluo-3 are target molecules. J. Immunol. 153:3523-3532.
    • (1994) J. Immunol. , vol.153 , pp. 3523-3532
    • Sommer, F.1    Bischof, S.2    Rollinghoff, M.3    Lohoff, M.4
  • 4
    • 0020578356 scopus 로고
    • Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines
    • Kartner, N., J.R. Riordan, and V. Ling. 1983. Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. Science. 221:1285-1288.
    • (1983) Science , vol.221 , pp. 1285-1288
    • Kartner, N.1    Riordan, J.R.2    Ling, V.3
  • 6
    • 0025924175 scopus 로고
    • Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines
    • Betz, M., and B.S. Fox. 1991. Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. J. Immunol. 146:108-113.
    • (1991) J. Immunol. , vol.146 , pp. 108-113
    • Betz, M.1    Fox, B.S.2
  • 7
    • 0025338731 scopus 로고
    • Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: Role of cAMP in T cell proliferation
    • Munoz, E., A.M. Zubiaga, M. Merrow, N.P. Sauter, and B.T. Huber. 1990. Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: role of cAMP in T cell proliferation. J. Exp. Med. 172: 95-103.
    • (1990) J. Exp. Med. , vol.172 , pp. 95-103
    • Munoz, E.1    Zubiaga, A.M.2    Merrow, M.3    Sauter, N.P.4    Huber, B.T.5
  • 8
    • 0028933795 scopus 로고
    • The regulation of immunity to Leishmania major
    • Reiner, S.L., and R.M. Locksley. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:151-177.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 151-177
    • Reiner, S.L.1    Locksley, R.M.2
  • 9
    • 0025195035 scopus 로고
    • Different response of TH1 cells for stimulation with anti-CD3 antibodies
    • Lohoff, M., E. Schmitt, A.B. Reske Kunz, and M. Rollinghoff. 1990. Different response of TH1 cells for stimulation with anti-CD3 antibodies. Eur. J. Immunol. 20:653-658.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 653-658
    • Lohoff, M.1    Schmitt, E.2    Reske Kunz, A.B.3    Rollinghoff, M.4
  • 10
    • 0024842827 scopus 로고
    • TCGF III/P40 is produced by naive murine CD4+ T cells but is not a general T cell growth factor
    • Schmiit, E., R. Van Brandwijk, J. Van Snick, B. Siebold, and E. Rude. 1989. TCGF III/P40 is produced by naive murine CD4+ T cells but is not a general T cell growth factor. Eur. J. Immunol. 19:2167-2170.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 2167-2170
    • Schmiit, E.1    Van Brandwijk, R.2    Van Snick, J.3    Siebold, B.4    Rude, E.5
  • 11
    • 0023679729 scopus 로고
    • Polyclonal B-cell stimulation by L3T4+ T cells in experimental leishmaniasis
    • Lohoff, M., C. Matzner, and M. Rollinghoff. 1988. Polyclonal B-cell stimulation by L3T4+ T cells in experimental leishmaniasis. Infect. Immun. 56: 2120-2124.
    • (1988) Infect. Immun. , vol.56 , pp. 2120-2124
    • Lohoff, M.1    Matzner, C.2    Rollinghoff, M.3
  • 12
    • 0023887659 scopus 로고
    • The specificity of the interaction between the agretope of an antigen and an Ia-molecule can depend on the T cell clonotype
    • Plachov, D., H.G. Fische,. A.B. Reske Kunz, and E. Rude. 1988. The specificity of the interaction between the agretope of an antigen and an Ia-molecule can depend on the T cell clonotype. Mol. Immunol. 25:611-620.
    • (1988) Mol. Immunol. , vol.25 , pp. 611-620
    • Plachov, D.1    Fische, H.G.2    Reske Kunz, A.B.3    Rude, E.4
  • 13
    • 0021175756 scopus 로고
    • Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: Interleukin 1 is required for the expression of receptors for interleukin 2
    • Kaye, J., S. Gillis, S.B. Mizel, E.M. Shevach, T.R. Malek, C.A. Dinarello, L.B. Lachman, and C.A. Janeway, Jr. 1984. Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2. J. Immunol. 133:1339-1345.
    • (1984) J. Immunol. , vol.133 , pp. 1339-1345
    • Kaye, J.1    Gillis, S.2    Mizel, S.B.3    Shevach, E.M.4    Malek, T.R.5    Dinarello, C.A.6    Lachman, L.B.7    Janeway Jr., C.A.8
  • 14
    • 0028181344 scopus 로고
    • V beta gene repertoires in T cells expanded in local self-healing and lethal systemic murine cutaneous leishmaniasis
    • Lohoff, M., M. Steinert, A. Weiss, M. Rollinghoff, R.S. Balderas, and A.N. Theofilopoulos, 1994. V beta gene repertoires in T cells expanded in local self-healing and lethal systemic murine cutaneous leishmaniasis. Eur. J. Immunol. 24:492-195.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 492-1195
    • Lohoff, M.1    Steinert, M.2    Weiss, A.3    Rollinghoff, M.4    Balderas, R.S.5    Theofilopoulos, A.N.6
  • 15
    • 0022500138 scopus 로고
    • Suppressive effect of cydosporin a on the development of Leishmania tropica-induced lesions in genetically susceptible BALB/c mice
    • Solbach, W., K. Forberg, E. Kammerer, C. Bogdan, and M. Rollinghoff. 1986. Suppressive effect of cydosporin A on the development of Leishmania tropica-induced lesions in genetically susceptible BALB/c mice. J. Immunol. 137:702-707.
    • (1986) J. Immunol. , vol.137 , pp. 702-707
    • Solbach, W.1    Forberg, K.2    Kammerer, E.3    Bogdan, C.4    Rollinghoff, M.5
  • 16
    • 0023872192 scopus 로고
    • Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors
    • Karasuyama, H., and F. Melchers. 1988. Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol 18:97-104.
    • (1988) Eur. J. Immunol , vol.18 , pp. 97-104
    • Karasuyama, H.1    Melchers, F.2
  • 17
    • 0025216585 scopus 로고
    • High gradient magnetic cell separation with MACS
    • Miltenyi, S., W. Muller, W. Weichel, and A. Radbruch. 1990. High gradient magnetic cell separation with MACS. Cytometry. 11:231-238.
    • (1990) Cytometry , vol.11 , pp. 231-238
    • Miltenyi, S.1    Muller, W.2    Weichel, W.3    Radbruch, A.4
  • 18
    • 0028054888 scopus 로고
    • Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs
    • Grant, C.E., G. Valdimarsson, D.R. Hipfner, K.C. Almquist, S.P. Cole, and R.G. Deeley. 1994. Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs. Cancer Res. 54:357-361.
    • (1994) Cancer Res. , vol.54 , pp. 357-361
    • Grant, C.E.1    Valdimarsson, G.2    Hipfner, D.R.3    Almquist, K.C.4    Cole, S.P.5    Deeley, R.G.6
  • 19
    • 0028171453 scopus 로고
    • Detection of the Mr 190,000 multidrug resistance protein MRP, with monoclonal antibodies
    • Hipfner, D.R., S.D. Gauldie, R.G. Deeley, and S.P.C. Cole. 1994. Detection of the Mr 190,000 multidrug resistance protein MRP, with monoclonal antibodies. Cancer Res. 54:5788-5792.
    • (1994) Cancer Res. , vol.54 , pp. 5788-5792
    • Hipfner, D.R.1    Gauldie, S.D.2    Deeley, R.G.3    Cole, S.P.C.4
  • 20
    • 0028000734 scopus 로고
    • Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies
    • Flens, MJ., M.A. Izquierdo, G.L. Scheffer, J.M. Fritz, C.J. Meijer, R.J. Scheper, and G.J. Zaman. 1994. Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies. Cancer Res. 54:4557-1563.
    • (1994) Cancer Res. , vol.54 , pp. 4557-11563
    • Flens, M.J.1    Izquierdo, M.A.2    Scheffer, G.L.3    Fritz, J.M.4    Meijer, C.J.5    Scheper, R.J.6    Zaman, G.J.7
  • 21
    • 0021852930 scopus 로고
    • Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies
    • Kartner, N., D. Evernden Porelle, G. Bradley, and V. Ling. 1985. Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature. 316:820-823.
    • (1985) Nature , vol.316 , pp. 820-823
    • Kartner, N.1    Evernden Porelle, D.2    Bradley, G.3    Ling, V.4
  • 22
    • 0022485356 scopus 로고
    • Characterization of a new drug-resistant human myeloma cell line that expresses P-glycoprotein
    • Dalton, W.S., B.G. Durie, D.S. Alberts, J.H. Gerlach, and A.E. Cress. 1986. Characterization of a new drug-resistant human myeloma cell line that expresses P-glycoprotein. Cancer Res. 46:5125-5130.
    • (1986) Cancer Res. , vol.46 , pp. 5125-5130
    • Dalton, W.S.1    Durie, B.G.2    Alberts, D.S.3    Gerlach, J.H.4    Cress, A.E.5
  • 23
    • 0029918142 scopus 로고    scopus 로고
    • ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids
    • Loe, D.W., K.C. Almquist, S.P. Cole, and R.G. Deeley. 1996. ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids. J. Biol. Chem. 271: 9683-9689.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9683-9689
    • Loe, D.W.1    Almquist, K.C.2    Cole, S.P.3    Deeley, R.G.4
  • 24
    • 0021149474 scopus 로고
    • The murine IL 2 receptor. I. Monoclonal antibodies that define distinct functional epitopes on activated T cells and react with activated B cells
    • Ortega, G., R.J. Robb, E.M. Shevach, and T.R. Malek. 1984. The murine IL 2 receptor. I. Monoclonal antibodies that define distinct functional epitopes on activated T cells and react with activated B cells. J. Immunol. 133: 1970-1975.
    • (1984) J. Immunol. , vol.133 , pp. 1970-1975
    • Ortega, G.1    Robb, R.J.2    Shevach, E.M.3    Malek, T.R.4
  • 25
    • 0021271862 scopus 로고
    • The interleukin-2 T-cell system: A new cell growth model
    • Cantrell. D.A., and K.A. Smith. 1984. The interleukin-2 T-cell system: a new cell growth model. Science. 224:1312-1316.
    • (1984) Science , vol.224 , pp. 1312-1316
    • Cantrell, D.A.1    Smith, K.A.2
  • 26
    • 0023161452 scopus 로고
    • Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antiv genic stimulation
    • Budd, R.C., J.C. Cerottini, C. Horvath, C. Bron, T. Pedrazzini, R.C. Howe, and H.R MacDonald. 1987. Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antiv genic stimulation. J. Immunol. 138:3120-3129.
    • (1987) J. Immunol. , vol.138 , pp. 3120-3129
    • Budd, R.C.1    Cerottini, J.C.2    Horvath, C.3    Bron, C.4    Pedrazzini, T.5    Howe, R.C.6    MacDonald, H.R.7
  • 27
    • 0001138830 scopus 로고
    • Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation
    • Birkeland, M.L., P. Johnson, I.S. Trowbridge, and E. Pure. 1989. Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation. Proc. Natl. Acad. Sci. USA. 86:6734-6738.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 6734-6738
    • Birkeland, M.L.1    Johnson, P.2    Trowbridge, I.S.3    Pure, E.4
  • 28
    • 0020577072 scopus 로고
    • A cell-surface molecule involved in organ-specific homing of lymphocytes
    • Gallatin. W.M., I.L. Weissman, and E.C. Butcher. 1983. A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature. 304:30-34.
    • (1983) Nature , vol.304 , pp. 30-34
    • Gallatin, W.M.1    Weissman, I.L.2    Butcher, E.C.3
  • 29
    • 0023774341 scopus 로고
    • Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation
    • Yokoyama, W.M., F. Koning, P.J. Kehn, G.M. Pereira, G. Stingl, J.E. Coligan, and E.M. Shevach. 1988. Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J. Immunol. 141: 369-376.
    • (1988) J. Immunol. , vol.141 , pp. 369-376
    • Yokoyama, W.M.1    Koning, F.2    Kehn, P.J.3    Pereira, G.M.4    Stingl, G.5    Coligan, J.E.6    Shevach, E.M.7
  • 30
    • 48749139369 scopus 로고
    • Limiting dilution analysis of the cells of immune system. I. the clonal basis of the immune response
    • Lefkovits, I., and H. Waldmann. 1984. Limiting dilution analysis of the cells of immune system. I. The clonal basis of the immune response. Immunol. Today. 5:265-268.
    • (1984) Immunol. Today , vol.5 , pp. 265-268
    • Lefkovits, I.1    Waldmann, H.2
  • 31
    • 0029939542 scopus 로고    scopus 로고
    • Structure and expression of the mRNA encoding the murine multidrug resistance protein (MRP), an ATP-binding cassette transporter
    • Stride, B.D., G. Valdimarsson, J.H. Gerlach, G.M. Wilson, S.P.C. Cole, and R.G. Deeley. 1996. Structure and expression of the mRNA encoding the murine multidrug resistance protein (MRP), an ATP-binding cassette transporter. Mol. Pharmacol. 49:962-971.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 962-971
    • Stride, B.D.1    Valdimarsson, G.2    Gerlach, J.H.3    Wilson, G.M.4    Cole, S.P.C.5    Deeley, R.G.6
  • 32
    • 0025935235 scopus 로고
    • Restoration of daunomycin retention in multidrug-resistant P388 cells hy submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative
    • Bocsch, D., K. Muller, A. Pourtier Manzanedo, and F. Loor. 1991. Restoration of daunomycin retention in multidrug-resistant P388 cells hy submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative. Exp. Cell Res. 196:26-32.
    • (1991) Exp. Cell Res. , vol.196 , pp. 26-32
    • Bocsch, D.1    Muller, K.2    Pourtier Manzanedo, A.3    Loor, F.4
  • 33
    • 0027473114 scopus 로고
    • Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein
    • Barrand, M.A., T. Rhodes, M.S. Center, and P.R. Twentyman. 1993. Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein. Eur. J. Cancer. 29A:408-415.
    • (1993) Eur. J. Cancer , vol.29 A , pp. 408-415
    • Barrand, M.A.1    Rhodes, T.2    Center, M.S.3    Twentyman, P.R.4
  • 34
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoprotein-mediated multidrug resistance
    • Endicott, J.A., and V. Ling. 1989. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu. Rev. Biochem. 58:137-171.
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 137-171
    • Endicott, J.A.1    Ling, V.2
  • 35
    • 0025655675 scopus 로고
    • Multidrug resistance and chemosensitization: Therapeutic implications for cancer chemotherapy
    • Georges, E., F.J. Sharom, and V. Ling. 1990. Multidrug resistance and chemosensitization: therapeutic implications for cancer chemotherapy. Adv. Pharmacol. 21:185-220.
    • (1990) Adv. Pharmacol. , vol.21 , pp. 185-220
    • Georges, E.1    Sharom, F.J.2    Ling, V.3
  • 37
    • 0028960201 scopus 로고
    • Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix
    • Manz, R., M. Assenmacher, E. Pfluger, S. Miltenyi, and A. Radbruch. 1995. Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix. Proc. Natl. Acad. Sci. USA. 92:1921-1925.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1921-1925
    • Manz, R.1    Assenmacher, M.2    Pfluger, E.3    Miltenyi, S.4    Radbruch, A.5
  • 38
    • 0011942665 scopus 로고
    • Hoechst 33342 dye uptake as a probe of membrane permeability changes in mammalian cells
    • Lalande, M.E., V. Ling, and R.G. Miller. 1981. Hoechst 33342 dye uptake as a probe of membrane permeability changes in mammalian cells. Proc. Natl. Acad. Sci. USA. 78:363-367.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 363-367
    • Lalande, M.E.1    Ling, V.2    Miller, R.G.3
  • 39
    • 0028608081 scopus 로고
    • Heterogeneity in P-glycoprotein (multidrug resistance) activity among murine peripheral T cells: Correlation with surface phenotype and effector function
    • Bommhardt, U., J.C. Ceroltini, and H.R. MacDonald. 1994. Heterogeneity in P-glycoprotein (multidrug resistance) activity among murine peripheral T cells: correlation with surface phenotype and effector function. Enr. J. Immunol. 24:2974-2981.
    • (1994) Enr. J. Immunol. , vol.24 , pp. 2974-2981
    • Bommhardt, U.1    Ceroltini, J.C.2    MacDonald, H.R.3
  • 40
    • 0028025021 scopus 로고
    • Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells
    • Abbaszadegan, M.R., B.W. Futscher, W.T. Klimecki, A. List, and W.S. Dalton. 1994. Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells. Cancer Res. 54: 4676-4679.
    • (1994) Cancer Res. , vol.54 , pp. 4676-4679
    • Abbaszadegan, M.R.1    Futscher, B.W.2    Klimecki, W.T.3    List, A.4    Dalton, W.S.5


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