BBA, a Synthetic Derivative of 23-hydroxybutulinic Acid, Reverses Multidrug Resistance by Inhibiting the Efflux Activity of MRP7 (ABCC10)

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Chen, Jun Jiang ^a,b,e   Patel, Atish ^b   Sodani, Kamlesh ^b   Xiao, Zhi Jie ^b   Tiwari, Amit K ^b,f   Zhang, Dong Mei ^c   Li, Ying Jie ^c   Yang, Dong Hua ^d   Ye, Wen Cai ^c   Chen, Si Dong ^a   Chen, Zhe Sheng ^b  

^a GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^b ST JOHN'S UNIVERSITY   (United States)

^c JINAN UNIVERSITY   (China)

^d FOX CHASE CANCER CENTER   (United States)

^e SOUTHERN MEDICAL UNIVERSITY   (China)

^f TUSKEGEE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

23 HYDROXYBUTULINIC ACID; ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; BETULIC ACID; CISPLATIN; DOCETAXEL; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 7; NAVELBINE; PACLITAXEL; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE;

ARTICLE; CELL MEMBRANE; DRUG MECHANISM; DRUG STRUCTURE; IC 50; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MEDICINAL PLANT; MULTIDRUG RESISTANCE; NONHUMAN; PLANT ROOT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PULSATILLA CHINENSIS;

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION; HEK293 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; PACLITAXEL; PROTEIN TRANSPORT; TRITERPENES;

EID: 84884247654     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074573     Document Type: Article

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