Microglial cell activation increases saturated and decreases monounsaturated fatty acid content, but both lipid species are proinflammatory

Lipids

Volumn 49, Issue 4, 2014, Pages 305-316

  Button, Emily B ^a   Mitchell, Andrew S ^a   Domingos, Marcia M ^a   Chung, Jessica H J ^a   Bradley, Ryan M ^a   Hashemi, Ashkan ^a   Marvyn, Phillip M ^a   Patterson, Ashley C ^a   Stark, Ken D ^a   Quadrilatero, Joe ^a   Duncan, Robin E ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

Author keywords

Apoptosis; BV2 microglial cells; Bystander cell death; Cyclooxygenase 2; Matrix metalloproteinase 9; Monounsaturated fatty acids; Necrosis; Proteolytic activity; Saturated fatty acids; SHSY 5Y neuronal cells

Indexed keywords

ACYL COENZYME A DESATURASE; FATTY ACID; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MONOUNSATURATED FATTY ACID; TRIACYLGLYCEROL;

ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; GENE EXPRESSION REGULATION; HUMAN; INFLAMMATION; METABOLISM; MICROGLIA; MOUSE; NERVE CELL; PATHOLOGY; TOXICITY;

ANIMALS; FATTY ACIDS; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; NEURONS; STEAROYL-COA DESATURASE; TRIGLYCERIDES;

EID: 84898912868     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-014-3882-y     Document Type: Article

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