-
1
-
-
84864670286
-
Polymeric gene delivery for diabetic treatment
-
Kim S.W. Polymeric gene delivery for diabetic treatment. Diabetes Metab J 2011, 35:317-326.
-
(2011)
Diabetes Metab J
, vol.35
, pp. 317-326
-
-
Kim, S.W.1
-
2
-
-
0037414781
-
Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis
-
Li Y., Hansotia T., Yusta B., Ris F., Halban P.A., Drucker D.J. Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis. J Biol Chem 2003, 278:471-478.
-
(2003)
J Biol Chem
, vol.278
, pp. 471-478
-
-
Li, Y.1
Hansotia, T.2
Yusta, B.3
Ris, F.4
Halban, P.A.5
Drucker, D.J.6
-
3
-
-
77953160144
-
Minireview: update on incretin biology: focus on glucagon-like peptide-1
-
Brubaker P.L. Minireview: update on incretin biology: focus on glucagon-like peptide-1. Endocrinology 2010, 151:1984-1989.
-
(2010)
Endocrinology
, vol.151
, pp. 1984-1989
-
-
Brubaker, P.L.1
-
4
-
-
79961175481
-
The future of incretin-based therapy: novel avenues-novel targets
-
Ahren B. The future of incretin-based therapy: novel avenues-novel targets. Diabetes Obes Metab 2011, 13(Suppl 1):158-166.
-
(2011)
Diabetes Obes Metab
, vol.13
, Issue.SUPPL 1
, pp. 158-166
-
-
Ahren, B.1
-
5
-
-
68949159829
-
Novel therapeutics for type 2 diabetes: incretin hormone mimetics (glucagon-like peptide-1 receptor agonists) and dipeptidyl peptidase-4 inhibitors
-
Verspohl E.J. Novel therapeutics for type 2 diabetes: incretin hormone mimetics (glucagon-like peptide-1 receptor agonists) and dipeptidyl peptidase-4 inhibitors. Pharmacol Ther 2009, 124:113-138.
-
(2009)
Pharmacol Ther
, vol.124
, pp. 113-138
-
-
Verspohl, E.J.1
-
6
-
-
69949163754
-
Exenatide and liraglutide: different approaches to develop GLP-1 receptor agonists (incretin mimetics)-preclinical and clinical results
-
Madsbad S. Exenatide and liraglutide: different approaches to develop GLP-1 receptor agonists (incretin mimetics)-preclinical and clinical results. Best Pract Res Clin Endocrinol Metab 2009, 23:463-477.
-
(2009)
Best Pract Res Clin Endocrinol Metab
, vol.23
, pp. 463-477
-
-
Madsbad, S.1
-
7
-
-
80052716020
-
From theory to clinical practice in the use of GLP-1 receptor agonists and DPP-4 inhibitors therapy
-
Dicembrini I., Pala L., Rotella C.M. From theory to clinical practice in the use of GLP-1 receptor agonists and DPP-4 inhibitors therapy. Exp Diabetes Res 2011, 2011:898913.
-
(2011)
Exp Diabetes Res
, vol.2011
, pp. 898913
-
-
Dicembrini, I.1
Pala, L.2
Rotella, C.M.3
-
8
-
-
51849168557
-
Adeno-associated virus-mediated gene transfer
-
Srivastava A. Adeno-associated virus-mediated gene transfer. J Cell Biochem 2008, 105:17-24.
-
(2008)
J Cell Biochem
, vol.105
, pp. 17-24
-
-
Srivastava, A.1
-
9
-
-
33645840126
-
Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors
-
Stieger K., Le Meur G., Lasne F., Weber M., Deschamps J.Y., Nivard D., et al. Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors. Mol Ther 2006, 13:967-975.
-
(2006)
Mol Ther
, vol.13
, pp. 967-975
-
-
Stieger, K.1
Le Meur, G.2
Lasne, F.3
Weber, M.4
Deschamps, J.Y.5
Nivard, D.6
-
10
-
-
59649122961
-
Long-term correction of inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy
-
Niemeyer G.P., Herzog R.W., Mount J., Arruda V.R., Tillson D.M., Hathcock J., et al. Long-term correction of inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy. Blood 2009, 113:797-806.
-
(2009)
Blood
, vol.113
, pp. 797-806
-
-
Niemeyer, G.P.1
Herzog, R.W.2
Mount, J.3
Arruda, V.R.4
Tillson, D.M.5
Hathcock, J.6
-
11
-
-
54249126862
-
Gene therapy using adeno-associated virus vectors
-
Daya S., Berns K.I. Gene therapy using adeno-associated virus vectors. Clin Microbiol Rev 2008, 21:583-593.
-
(2008)
Clin Microbiol Rev
, vol.21
, pp. 583-593
-
-
Daya, S.1
Berns, K.I.2
-
12
-
-
77950838482
-
CERE-110, an adeno-associated virus-based gene delivery vector expressing human nerve growth factor for the treatment of Alzheimer's disease
-
Mandel R.J. CERE-110, an adeno-associated virus-based gene delivery vector expressing human nerve growth factor for the treatment of Alzheimer's disease. Curr Opin Mol Ther 2010, 12:240-247.
-
(2010)
Curr Opin Mol Ther
, vol.12
, pp. 240-247
-
-
Mandel, R.J.1
-
13
-
-
44249120315
-
Effect of gene therapy on visual function in Leber's congenital amaurosis
-
Bainbridge J.W., Smith A.J., Barker S.S., Robbie S., Henderson R., Balaggan K., et al. Effect of gene therapy on visual function in Leber's congenital amaurosis. N Engl J Med 2008, 358:2231-2239.
-
(2008)
N Engl J Med
, vol.358
, pp. 2231-2239
-
-
Bainbridge, J.W.1
Smith, A.J.2
Barker, S.S.3
Robbie, S.4
Henderson, R.5
Balaggan, K.6
-
14
-
-
77954116887
-
NLX-P101, an adeno-associated virus gene therapy encoding glutamic acid decarboxylase, for the potential treatment of Parkinson's disease
-
Diaz-Nido J. NLX-P101, an adeno-associated virus gene therapy encoding glutamic acid decarboxylase, for the potential treatment of Parkinson's disease. Curr Opin Invest Drugs 2010, 11:813-822.
-
(2010)
Curr Opin Invest Drugs
, vol.11
, pp. 813-822
-
-
Diaz-Nido, J.1
-
15
-
-
77649242176
-
Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration
-
Simonelli F., Maguire A.M., Testa F., Pierce E.A., Mingozzi F., Bennicelli J.L., et al. Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration. Mol Ther 2010, 18:643-650.
-
(2010)
Mol Ther
, vol.18
, pp. 643-650
-
-
Simonelli, F.1
Maguire, A.M.2
Testa, F.3
Pierce, E.A.4
Mingozzi, F.5
Bennicelli, J.L.6
-
16
-
-
21244443038
-
Salivary glands as a potential gene transfer target for gene therapeutics of some monogenetic endocrine disorders
-
Voutetakis A., Bossis I., Kok M.R., Zhang W., Wang J., Cotrim A.P., et al. Salivary glands as a potential gene transfer target for gene therapeutics of some monogenetic endocrine disorders. J Endocrinol 2005, 185:363-372.
-
(2005)
J Endocrinol
, vol.185
, pp. 363-372
-
-
Voutetakis, A.1
Bossis, I.2
Kok, M.R.3
Zhang, W.4
Wang, J.5
Cotrim, A.P.6
-
17
-
-
0031952892
-
Systemic action of human growth hormone following adenovirus-mediated gene transfer to rat submandibular glands
-
He X., Goldsmith C.M., Marmary Y., Wellner R.B., Parlow A.F., Nieman L.K., et al. Systemic action of human growth hormone following adenovirus-mediated gene transfer to rat submandibular glands. Gene Ther 1998, 5:537-541.
-
(1998)
Gene Ther
, vol.5
, pp. 537-541
-
-
He, X.1
Goldsmith, C.M.2
Marmary, Y.3
Wellner, R.B.4
Parlow, A.F.5
Nieman, L.K.6
-
18
-
-
79951917693
-
Human parathyroid hormone is secreted primarily into the bloodstream after rat parotid gland gene transfer
-
Adriaansen J., Perez P., Zheng C., Collins M.T., Baum B.J. Human parathyroid hormone is secreted primarily into the bloodstream after rat parotid gland gene transfer. Hum Gene Ther 2011, 22:84-92.
-
(2011)
Hum Gene Ther
, vol.22
, pp. 84-92
-
-
Adriaansen, J.1
Perez, P.2
Zheng, C.3
Collins, M.T.4
Baum, B.J.5
-
19
-
-
80053442737
-
Gene delivery in salivary glands: from the bench to the clinic
-
Samuni Y., Baum B.J. Gene delivery in salivary glands: from the bench to the clinic. Biochim Biophys Acta 2011, 1812:1515-1521.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 1515-1521
-
-
Samuni, Y.1
Baum, B.J.2
-
20
-
-
38849196303
-
Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease
-
Bertilsson G., Patrone C., Zachrisson O., Andersson A., Dannaeus K., Heidrich J., et al. Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease. J Neurosci Res 2008, 86:326-338.
-
(2008)
J Neurosci Res
, vol.86
, pp. 326-338
-
-
Bertilsson, G.1
Patrone, C.2
Zachrisson, O.3
Andersson, A.4
Dannaeus, K.5
Heidrich, J.6
-
21
-
-
0035691617
-
The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas
-
Szkudelski T. The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 2001, 50:537-546.
-
(2001)
Physiol Res
, vol.50
, pp. 537-546
-
-
Szkudelski, T.1
-
22
-
-
31544453593
-
Glucagon-like peptide 1 (GLP-1) and metabolic diseases
-
Rotella C.M., Pala L., Mannucci E. Glucagon-like peptide 1 (GLP-1) and metabolic diseases. J Endocrinol Invest 2005, 28:746-758.
-
(2005)
J Endocrinol Invest
, vol.28
, pp. 746-758
-
-
Rotella, C.M.1
Pala, L.2
Mannucci, E.3
-
23
-
-
66149108722
-
Glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized clinical trials
-
Monami M., Marchionni N., Mannucci E. Glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized clinical trials. Eur J Endocrinol 2009, 160:909-917.
-
(2009)
Eur J Endocrinol
, vol.160
, pp. 909-917
-
-
Monami, M.1
Marchionni, N.2
Mannucci, E.3
-
24
-
-
33646058571
-
Metabolic effects of the incretin mimetic exenatide in the treatment of type 2 diabetes
-
Schnabel C.A., Wintle M., Kolterman O. Metabolic effects of the incretin mimetic exenatide in the treatment of type 2 diabetes. Vasc Health Risk Manage 2006, 2:69-77.
-
(2006)
Vasc Health Risk Manage
, vol.2
, pp. 69-77
-
-
Schnabel, C.A.1
Wintle, M.2
Kolterman, O.3
-
25
-
-
0034456212
-
Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats
-
Szayna M., Doyle M.E., Betkey J.A., Holloway H.W., Spencer R.G., Greig N.H., et al. Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats. Endocrinology 2000, 141:1936-1941.
-
(2000)
Endocrinology
, vol.141
, pp. 1936-1941
-
-
Szayna, M.1
Doyle, M.E.2
Betkey, J.A.3
Holloway, H.W.4
Spencer, R.G.5
Greig, N.H.6
-
26
-
-
37849004995
-
NT4 a NAP prokaryotic expression vector construction and in escherichia coli expression
-
Yu Y., Jang W., Xin Y. NT4 a NAP prokaryotic expression vector construction and in escherichia coli expression. J Neurol 2004, 37:260-261.
-
(2004)
J Neurol
, vol.37
, pp. 260-261
-
-
Yu, Y.1
Jang, W.2
Xin, Y.3
-
28
-
-
0032711845
-
Delayed expression of adeno-associated virus vector DNA
-
Afione S.A., Wang J., Walsh S., Guggino W.B., Flotte T.R. Delayed expression of adeno-associated virus vector DNA. Intervirology 1999, 42:213-220.
-
(1999)
Intervirology
, vol.42
, pp. 213-220
-
-
Afione, S.A.1
Wang, J.2
Walsh, S.3
Guggino, W.B.4
Flotte, T.R.5
-
29
-
-
0029923638
-
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors
-
Ferrari F.K., Samulski T., Shenk T., Samulski R.J. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J Virol 1996, 70:3227-3234.
-
(1996)
J Virol
, vol.70
, pp. 3227-3234
-
-
Ferrari, F.K.1
Samulski, T.2
Shenk, T.3
Samulski, R.J.4
-
30
-
-
0346777307
-
Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo
-
McCarty D.M., Fu H., Monahan P.E., Toulson C.E., Naik P., Samulski R.J. Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo. Gene Ther 2003, 10:2112-2118.
-
(2003)
Gene Ther
, vol.10
, pp. 2112-2118
-
-
McCarty, D.M.1
Fu, H.2
Monahan, P.E.3
Toulson, C.E.4
Naik, P.5
Samulski, R.J.6
-
31
-
-
1542347741
-
Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors
-
Thomas C.E., Storm T.A., Huang Z., Kay M.A. Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors. J Virol 2004, 78:3110-3122.
-
(2004)
J Virol
, vol.78
, pp. 3110-3122
-
-
Thomas, C.E.1
Storm, T.A.2
Huang, Z.3
Kay, M.A.4
-
32
-
-
84863760366
-
Sustained exendin-4 secretion through gene therapy targeting salivary glands in two different rodent models of obesity/type 2 diabetes
-
Di Pasquale G., Dicembrini I., Raimondi L., Pagano C., Egan J.M., Cozzi A., et al. Sustained exendin-4 secretion through gene therapy targeting salivary glands in two different rodent models of obesity/type 2 diabetes. PLoS One 2012, 7:e40074.
-
(2012)
PLoS One
, vol.7
-
-
Di Pasquale, G.1
Dicembrini, I.2
Raimondi, L.3
Pagano, C.4
Egan, J.M.5
Cozzi, A.6
-
33
-
-
0029800573
-
Evidence for the systemic delivery of a transgene product from salivary glands
-
Kagami H., O'Connell B.C., Baum B.J. Evidence for the systemic delivery of a transgene product from salivary glands. Hum Gene Ther 1996, 7:2177-2184.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 2177-2184
-
-
Kagami, H.1
O'Connell, B.C.2
Baum, B.J.3
-
34
-
-
0033589813
-
Polarized secretion of transgene products from salivary glands in vivo
-
Baum B.J., Berkman M.E., Marmary Y., Goldsmith C.M., Baccaglini L., Wang S., et al. Polarized secretion of transgene products from salivary glands in vivo. Hum Gene Ther 1999, 10:2789-2797.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 2789-2797
-
-
Baum, B.J.1
Berkman, M.E.2
Marmary, Y.3
Goldsmith, C.M.4
Baccaglini, L.5
Wang, S.6
-
36
-
-
0038372164
-
Distribution and toxicity resulting from adenoviral vector administration to a single salivary gland in adult rats
-
O'Connell B.C., Zheng C., Jacobson-Kram D., Baum B.J. Distribution and toxicity resulting from adenoviral vector administration to a single salivary gland in adult rats. J Oral Pathol Med 2003, 32:414-421.
-
(2003)
J Oral Pathol Med
, vol.32
, pp. 414-421
-
-
O'Connell, B.C.1
Zheng, C.2
Jacobson-Kram, D.3
Baum, B.J.4
-
37
-
-
84875027061
-
Expression and secretion of human proinsulin-b10 from mouse salivary glands: implications for the treatment of type I diabetes mellitus
-
Rowzee A.M., Perez-Riveros P.J., Zheng C., Krygowski S., Baum B.J., Cawley N.X. Expression and secretion of human proinsulin-b10 from mouse salivary glands: implications for the treatment of type I diabetes mellitus. PLoS One 2013, 8:e59222.
-
(2013)
PLoS One
, vol.8
-
-
Rowzee, A.M.1
Perez-Riveros, P.J.2
Zheng, C.3
Krygowski, S.4
Baum, B.J.5
Cawley, N.X.6
-
38
-
-
84859100106
-
TACI-Fc gene therapy improves autoimmune sialadenitis but not salivary gland function in non-obese diabetic mice
-
Vosters J.L., Roescher N., Illei G.G., Chiorini J.A., Tak P.P. TACI-Fc gene therapy improves autoimmune sialadenitis but not salivary gland function in non-obese diabetic mice. Oral Dis 2012, 18:365-374.
-
(2012)
Oral Dis
, vol.18
, pp. 365-374
-
-
Vosters, J.L.1
Roescher, N.2
Illei, G.G.3
Chiorini, J.A.4
Tak, P.P.5
-
39
-
-
10744227749
-
Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial
-
Moss R.B., Rodman D., Spencer L.T., Aitken M.L., Zeitlin P.L., Waltz D., et al. Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial. Chest 2004, 125:509-521.
-
(2004)
Chest
, vol.125
, pp. 509-521
-
-
Moss, R.B.1
Rodman, D.2
Spencer, L.T.3
Aitken, M.L.4
Zeitlin, P.L.5
Waltz, D.6
-
40
-
-
34249891874
-
Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes
-
Kim D., MacConell L., Zhuang D., Kothare P.A., Trautmann M., Fineman M., et al. Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes. Diabetes Care 2007, 30:1487-1493.
-
(2007)
Diabetes Care
, vol.30
, pp. 1487-1493
-
-
Kim, D.1
MacConell, L.2
Zhuang, D.3
Kothare, P.A.4
Trautmann, M.5
Fineman, M.6
-
41
-
-
77952502739
-
Induction of insulin receptor substrate-2 expression by Fc fusion to exendin-4 overexpressed in E. coli: a potential long-acting glucagon-like peptide-1 mimetic
-
Kim J.W., Kim K., Ahn Y., Jeong H., Ryu S., Lee S., et al. Induction of insulin receptor substrate-2 expression by Fc fusion to exendin-4 overexpressed in E. coli: a potential long-acting glucagon-like peptide-1 mimetic. BMB Rep 2010, 43:146-149.
-
(2010)
BMB Rep
, vol.43
, pp. 146-149
-
-
Kim, J.W.1
Kim, K.2
Ahn, Y.3
Jeong, H.4
Ryu, S.5
Lee, S.6
-
42
-
-
44349157048
-
Preparation and characterization of a novel exendin-4 human serum albumin fusion protein expressed in Pichia pastoris
-
Huang Y.S., Chen Z., Chen Y.Q., Ma G.C., Shan J.F., Liu W., et al. Preparation and characterization of a novel exendin-4 human serum albumin fusion protein expressed in Pichia pastoris. J Pept Sci 2008, 14:588-595.
-
(2008)
J Pept Sci
, vol.14
, pp. 588-595
-
-
Huang, Y.S.1
Chen, Z.2
Chen, Y.Q.3
Ma, G.C.4
Shan, J.F.5
Liu, W.6
-
43
-
-
67650682753
-
Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells
-
Peyot M.L., Gray J.P., Lamontagne J., Smith P.J., Holz G.G., Madiraju S.R., et al. Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells. PLoS One 2009, 4:e6221.
-
(2009)
PLoS One
, vol.4
-
-
Peyot, M.L.1
Gray, J.P.2
Lamontagne, J.3
Smith, P.J.4
Holz, G.G.5
Madiraju, S.R.6
|