What causes internalising traits and autistic traits to co-occur in adolescence? A community-based twin study

Journal of Abnormal Child Psychology

Volumn 42, Issue 4, 2014, Pages 601-610

  Scherff, Aline ^a   Taylor, Mark ^b   Eley, Thalia C ^c   Happé, Francesca ^c   Charman, Tony ^c   Ronald, Angelica ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Adolescence; Autistic disorder; Comorbidity; Genetics; Internalising disorders

Indexed keywords

ADOLESCENT; ANXIETY; ARTICLE; AUTISM; CHILD; COMORBIDITY; CONTROL; DEPRESSION; FACTORIAL ANALYSIS; FEMALE; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; MALE; PSYCHOLOGICAL ASPECT; SOCIAL ENVIRONMENT; TWINS;

ADOLESCENT; ANXIETY; AUTISTIC DISORDER; CHILD; COMORBIDITY; DEPRESSION; DISEASES IN TWINS; FACTOR ANALYSIS, STATISTICAL; FEMALE; GENE-ENVIRONMENT INTERACTION; HUMANS; INTERNAL-EXTERNAL CONTROL; MALE; SOCIAL ENVIRONMENT;

EID: 84898860691     PISSN: 00910627     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10802-013-9796-y     Document Type: Article

References (49)

1. Achenbach, T. M. (1991). Manual for the child behaviour checklist 1991 profile. Burlington: University of Vermont, Department of Psychiatry.
2. American Psychiatric Association APA (2000). Diagnostic and statistical manual of mental disorders (Fourth Edition: DSM-IV-TR ed.): American Psychiatric Pub.
3. Angold, A., Costello, E. J., Messer, S. C., Pickles, A., Winder, F., & Silver, D. (1995). Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents. International Journal of Methods in Psychiatric Research, 5, 237-249.
4. Baron-Cohen, S., Hoekstra, R. A., Knickmeyer, R., & Wheelwright, S. (2006). The autism-spectrum quotient (AQ)-adolescent version. Journal of Autism and Developmental Disorders, 36, 343-350.
5. Bolton, P., Macdonald, H., Pickles, A., Rios, P., Goode, S., Crowson, M., et al. (1994). A case-control family history study of autism. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 35, 877-900.
6. Burt, S. A. (2009). Rethinking environmental contributions to child and adolescent psychopathology: a meta-analysis of shared environmental influences. Psychological Bulletin, 135, 608-637.
7. Constantino, J. N., & Charman, T. (2012). Gender bias, female resilience, and the sex ratio in autism. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 756-758.
8. De Bruin, E. I., Ferdinand, R. F., Meester, S., de Nijs, P. F. A., & Verheij, F. (2007). High rates of psychiatric co-morbidity in PDD-NOS. Journal of Autism and Developmental Disorders, 37, 877-886.
9. Dworzynski, K., Ronald, A., Bolton, P., & Happé, F. (2012). How different are girls and boys above and below the diagnostic threshold for autism spectrum disorders? Journal of the American Academy of Child and Adolescent Psychiatry, 51, 788-797.
10. Fergusson, D. M., Horwood, L. J., & Boden, J. M. (2006). Structure of internalising symptoms in early adulthood. British Journal of Psychiatry, 189, 540-546.
11. Goodman, R. (1997). The strengths and difficulties questionnaire: a research note. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 38, 581-586.
12. Goodman, R. (2001). Psychometric properties of the strengths and difficulties questionnaire. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 1337-1345.
13. Goodman, R., & Scott, S. (1999). Comparing the strengths and difficulties questionnaire and the child behavior checklist: Is small beautiful? Journal of Abnormal Child Psychology, 27, 17-24.
14. Goodwin, R. D., Fergusson, D. M., & Horwood, L. J. (2004). Early anxious/withdrawn behaviours predict later internalising disorders. Journal of Child Psychology and Psychiatry, 45, 874-883.
15. Gregory, A. M., & Eley, T. C. (2011). The genetic basis of child and adolescent anxiety. Anxiety disorders in children and adolescents (2nd ed.). Cambridge: Cambridge University Press.
16. Hallett, V., Ronald, A., & Happé, F. (2009). Investigating the association between autistic-like and internalizing traits in a community-based twin sample. Journal of the American Academy of Child and Adolescent Psychiatry, 48, 618-627.
17. Hallett, V., Ronald, A., Rijsdijk, F., & Happé, F. (2010). Association of autistic-like and internalizing traits during childhood: a longitudinal twin study. American Journal of Psychiatry, 167, 809-817.
18. Hallett, V., Ronald, A., Rijsdijk, F., & Happé, F. (2012). Disentangling the associations between autistic-like and internalizing traits: a community based twin study. Journal of Abnormal Child Psychology, 40, 815-827.
19. Happé, F., & Ronald, A. (2008). The 'fractionable autism triad': a review of evidence from behavioural, genetic, cognitive and neural research. Neuropsychology Review, 18, 287-304.
20. Happé, F., Ronald, A., & Plomin, R. (2006). Time to give up on a single explanation for autism. Nature Neuroscience, 9, 1218-1220.
21. Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2013). Twins early development study (teds): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood. Twin Research and Human Genetics, 16, 117-125.
22. Hoekstra, R. A., Bartels, M., Cath, D. C., & Boomsma, D. I. (2008). Factor structure, reliability and criterion validity of the autism-spectrum quotient (AQ): a study in Dutch population and patient groups. Journal of Autism and Developmental Disorders, 38, 1555-1566.
23. Hoekstra, R. A., Bartels, M., Hudziak, J. J., van Beijsterveldt, T. C. E. M., & Boomsma, D. I. (2007). Genetic and environmental covariation between autistic traits and behavioral problems. Twin Research and Human Genetics, 10, 853-860.
24. Hoekstra, R. A., Vinkhuyzen, A. A. E., Wheelwright, S., Bartels, M., Boomsma, D. I., Baron-Cohen, S., et al. (2011). The construction and validation of an abridged version of the autism-spectrum quotient (AQ-Short). Journal of Autism and Developmental Disorders, 41, 589-596.
25. Hurst, R. M., Mitchell, J. T., Kimbrel, N. A., Kwapil, T. K., & Nelson-Gray, R. O. (2007). Examination of the reliability and factor structure of the autism spectrum quotient (AQ) in a non-clinical sample. Personality and Individual Differences, 43, 1938-1949.
26. Ketelaars, C., Horwitz, E., Sytema, S., Bos, J., Wiersma, D., Minderaa, R., et al. (2008). Brief report: adults with mild autism spectrum disorders (asd): scores on the autism spectrum quotient (AQ) and comorbid psychopathology. Journal of Autism and Developmental Disorders, 38, 176-180.
27. Lau, J. Y. F., & Eley, T. C. (2010). The genetics of mood disorders. Annual Review of Clinical Psychology, 6, 313-337.
28. Lewinsohn, P. M., Clarke, G. N., Seeley, J. R., & Rohde, P. (1994). Major depression in community adolescents - age at onset, episode duration, and time to recurrence. Journal of the American Academy of Child and Adolescent Psychiatry, 33, 809-818.
29. Losh, M., Childress, D., Lam, K., & Piven, J. (2008). Defining key features of the broad autism phenotype: a comparison across parents of multiple- and single-incidence autism families. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 147, 424-433.
30. Lundström, S., Chang, Z., Kerekes, N., Gumpert, C. H., Råstam, M., Gillberg, C., et al. (2011). Autistic-like traits and their association with mental health problems in two nationwide twin cohorts of children and adults. Psychological Medicine, 41, 2423-2433.
31. Lundström, S., Chang, Z., Råstam, M., Gillberg, C., Larsson, H., Anckarsäter, H., et al. (2012). Autism spectrum disorders and autistic-like traits: similar etiology in the extreme end and the normal variation. Archives of General Psychiatry, 69, 46-52.
32. Moffitt, T. E., Harrington, H., Caspi, A., Kim-Cohen, J., Goldberg, D., Gregory, A. M., et al. (2007). Depression and generalized anxiety disorder - cumulative and sequential comorbidity in a birth cohort followed prospectively to age 32 years. Archives of General Psychiatry, 64, 651-660.
33. Neale, M. C. (1997). Mx: Statistical modeling (4th ed.). Charlottesville: Department of Psychiatry, Medical College of Virginia.
34. Price, T. S., Freeman, B., Craig, I., Petrill, S. A., Ebersole, L., & Plomin, R. (2000). Infant zygosity can be assigned by parental report questionnaire data. Twin Research, 3, 129-133
35. Robinson, E. B., Koenen, K. C., McCormick, M. C., Munir, K., Hallett, V., Happé, F. et al. (2011a). Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5%, 2.5%, and 1%). Archives of General Psychiatry, 68, 1113-1121.
36. Robinson, E. B., Koenen, K. C., McCormick, M. C., Munir, K., Hallett, V., Happé, F., et al. (2012). A multivariate twin study of autistic traits in 12-year-olds: testing the fractionable autism triad hypothesis. Behavior Genetics, 42, 245-255.
37. Robinson, E. B., Munir, K., Munafo, M. R., Hughes, M., McCormick, M. C., & Koenen, K. C. (2011b). Stability of autistic traits in the general population: further evidence for a continuum of impairment. Journal of the American Academy of Child and Adolescent Psychiatry, 50, 376-384.
38. Ronald, A., Happé, F., Bolton, P., Butcher, L. M., Price, T. S., Wheelwright, S., et al. (2006). Genetic heterogeneity between the three components of the autism spectrum: a twin study. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 691-699.
39. Ronald, A., Happé, F., & Plomin, R. (2005). The genetic relationship between individual differences in social and nonsocial behaviours characteristic of autism. Developmental Science, 8, 444-458.
40. Ronald, A., & Hoekstra, R. A. (2011). Autism spectrum disorders and autistic traits: a decade of new twin studies. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 156, 255-274.
41. Ronald, A., Larsson, H., Anckarsäter, H., & Lichtenstein, P. (2011). A twin study of autism symptoms in sweden. Molecular Psychiatry, 16, 1039-1047.
42. Scott, F. J., Baron-Cohen, S., Bolton, P., & Brayne, C. (2002). Brief report - prevalence of autism spectrum conditions in children aged 5-11 years in cambridgeshire, uk. Autism, 6, 231-237.
43. Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 921-929.
44. Van Roy, B., Veenstra, M., & Clench-Aas, J. (2008). Construct validity of the five-factor strengths and difficulties questionnaire (SDQ) in pre-, early, and late adolescence. Journal of Child Psychology and Psychiatry, 49, 1304-1312.
45. Van Steensel, F. J. A., Bogels, S. M., & Perrin, S. (2011). Anxiety disorders in children and adolescents with autistic spectrum disorders: a meta-analysis. Clinical Child and Family Psychology Review, 14, 302-317.
46. Wakabayashi, A., Baron-Cohen, S., & Wheelwright, S. (2006). Are autistic traits an independent personality dimension? A study of the autism-spectrum quotient (AQ) and the NEO-PI-R. Personality and Individual Differences, 41, 873-883.
47. World Health Organisation WHO. (1992). ICD-10 classifications of mental and behavioural disorder: Clinical descriptions and diagnostic guidelines. Geneva: World Health Organisation.
48. Wood, J. J., & Gadow, K. D. (2010). Exploring the nature and function of anxiety in youth with autism spectrum disorders. Clinical Psychology-Science and Practice, 17, 281-292.
49. Woodbury-Smith, M. R., Robinson, J., Wheelwright, S., & Baron-Cohen, S. (2005). Screening adults for asperger syndrome using the AQ: a preliminary study of its diagnostic validity in clinical practice. Journal of Autism and Developmental Disorders, 35, 331-335.