Genetic and environmental covariation between autistic traits and behavioral problems

Twin Research and Human Genetics

Volumn 10, Issue 6, 2007, Pages 853-860

  Hoekstra, Rosa A ^a,c   Bartels, Meike ^a   Hudziak, James J ^b   Van Beijsterveldt, Toos C E M ^a   Boomsma, Dorret I ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b UNIVERSITY OF VERMONT   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; AUTISM; BEHAVIOR DISORDER; CHILD; CONTROLLED STUDY; ENVIRONMENT; ENVIRONMENTAL FACTOR; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; MALE; POPULATION; PRIORITY JOURNAL; SCORING SYSTEM; SELF REPORT; SIBLING; SOCIAL BEHAVIOR; SOCIAL PROBLEM; TWINS;

AUTISTIC DISORDER; CHILD; CHILD BEHAVIOR DISORDERS; CHILD, PRESCHOOL; ENVIRONMENT; FEMALE; HUMANS; INFANT; MALE; NETHERLANDS; REGISTRIES; REGRESSION ANALYSIS; TWINS;

EID: 37349103964     PISSN: 18324274     EISSN: None     Source Type: Journal    
DOI: 10.1375/twin.10.6.853     Document Type: Article

References (40)

1. Achenbach, T. M. & Rescorla, L. A. (2001). Manual for the ASEBA School-age Forms and Profiles. Burlington, VT: University of Vermont, research Center for Children, Youth & Families.
2. Bailey, A., Palferman, S., Heavey, L., & Le Couteur, A. (1998). Autism: The phenotype in relatives. Journal of Autism and Developmental Disorders, 28, 369-392.
3. Baron-Cohen, S., Wheelwright, S., Skinner, R., & Martin, C. E. (2001). The Autism Spectrum Quotient (AQ): Evidence from Asperger Syndrome/High Functioning Autism, Males and Females, Scientists and Mathematicians. Journal of Autism and Developmental Disorders, 31, 5-17.
4. Bartels, M., Hudziak, J. J., Van den Oord, E. J. C. G., Van Beijsterveldt, C. E. M., Rietveld, M. J. H., & Boomsma, D. I. (2003). Co-occurrence of Aggressive Behavior and Rule-Breaking Behavior at Age 12: Multi-Rater Analyses. Behavior Genetics, 33, 607-621.
5. Bartels, M., Van Beijsterveldt, C. E. M., Derks, E. M., Stroet, T. M., Polderman, T. J. C., Hudziak, J. J., & Boomsma, D. I. (2007). Young Netherlands Twin Register (Y-NTR): A longitudinal multiple informant study of problem behavior. Twin Research and Human Genetics, 10, 3-11.
6. Bolte, S., Dickhut, H., & Poustka, F. (1999). Patterns of parent-reported problems indicative in autism. Psychopathology, 32, 93-97.
7. Bolton, P., Macdonald, H., Pickles, A., Rios, P., Goode, S., Crowson, M., Bailey, A., & Rutter, M. (1994). A Case - Control Family History Study of Autism. Journal of Child Psychology and Psychiatry and Allied Disciplines, 35, 877-900.
8. Bolton, P. F., Pickles, A., Murphy, M., & Rutter, M. (1998). Autism, affective and other psychiatric disorders: Patterns of familial aggregation. Psychological Medicine, 28, 385-395.
9. Boomsma, D. I., De Geus, E. J. C., Vink, J. M., Stubbe, J. H., Distel, M. A., Hottenga, J. J., Posthuma, D., Van Beijsterveldt, C. E. M., Hudziak, J. J., Bartels, M., & Willemsen, A. H. M. (2006). Netherlands Twin Register: From twins to twin families. Twin Research and Human Genetics, 9, 849-857.
10. Constantino, J. N., Hudziak, J. J., & Todd, R. D. (2003). Deficits in reciprocal social behavior in male twins: Evidence for a genetically independent domain of psychopathology. Journal of the American Academy of Child and Adolescent Psychiatry, 42, 458-467.
11. Constantino, J. N. & Todd, R. D. (2000). Genetic structure of reciprocal social behavior. American Journal of Psychiatry, 157, 2043-2045.
12. Constantino, J. N. & Todd, R. D. (2003). Autistic traits in the general population: A twin study. Archives of General Psychiatry, 60, 524-530.
13. Freitag, C. M. (2007). The genetics of autistic disorders and its clinical relevance: A review of the literature. Molecular Psychiatry, 12, 2-22.
14. Goldstein, S. & Schwebach, A. J. (2004). The comorbidity of Pervasive Developmental Disorder and Attention Deficit Hyperactivity Disorder: Results of a retrospective chart review. Journal of Autism and Developmental Disorders, 34, 329-339.
15. Hoekstra, R. A., Bartels, M., Cath, D. C., & Boomsma, D. I. (2007a). Factor structure of the broader autism phenotype: A study using the Dutch translation of the Autism-Spectrum Quotient (AQ). Manuscript submitted for publication.
16. Hoekstra, R. A., Bartels, M., Verweij, C. J. H., & Boomsma, D. I. (2007b). Heritability of autistic traits in the general population. Archives of Pediatrics and Adolescent Medicine, 161, 372-377.
17. Howlin, P. (2000). Outcome in adult life for more able individuals with autism or Asperger syndrome. Autism, 4, 63-83.
18. Lainhart, J. E. & Folstein, S. E. (1994). Affective disorders in people with autism: A review of published cases. Journal of Autism and Developmental Disorders, 24, 587-601.
19. Landa, R., Piven, J., Wzorek, M. M., Gayle, J. O., Chase, G. A., & Folstein, S. E. (1992). Social language use in parents of autistic individuals. Psychological Medicine, 22, 245-254.
20. Leyfer, O. T., Folstein, S. E., Bacalman, S., Davis, N. O., Dinh, E., Morgan, J., Tager-Flusberg, H., & Lainhart, J. E. (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36, 849-861.
21. Luteijn, E. F., Serra, M., Jackson, S., Steenhuis, M. P., Althaus, M., Volkmar, F., & Minderaa, R. (2000). How unspecified are disorders of children with a pervasive developmental disorder not otherwise specified? A study of social problems in children with PDD-NOS and ADHD. European Child and Adolescent Psychiatry, 9, 168-179.
22. Matson, J. L. & Nebel-Schwalm, M. S. (2006). Comorbid psychopathology with autism spectrum disorder in children: An overview. Research in Developmental Disabilities, 28, 341-352.
23. Micali, N., Chakrabarti, S., & Fombonne, E. (2004). The broad autism phenotype: Findings from an epidemiological survey. Autism, 8, 21-37.
24. Neale, M. C., Boker, S. M., Xie, G., & Maes, H. H. (2006). Mx: Statistical modeling. (7th ed.) Richmond: VCU, Department of Psychiatry.
25. Neale, M. C. & Cardon, L. D. (1992). Methodology for Genetic Studies of Twins and Families. Dordrecht: Kluwer Academic.
26. Piven, J. & Palmer, P. (1999). Psychiatric disorder and the broad autism phenotype: Evidence from a family study of multiple-incidence autism families. American Journal of Psychiatry, 156, 557-563.
27. Piven, J., Palmer, P., Jacobi, D., Childress, D., & Arndt, S. (1997). Broader autism phenotype: Evidence from a family history study of multiple-incidence autism families. American Journal of Psychiatry, 154, 185-190.
28. Posthuma, D. & Boomsma, D. I. (2000). A note on the statistical power in extended twin designs. Behavior Genetics, 30, 147-158.
29. Rietveld, M. J. H., Van der Valk, J. C., Bongers, I. L., Stroet, T. M., Slagboom, P. E., & Boomsma, D. I. (2000). Zygosity diagnosis in young twins by parental report. Twin Research, 3, 134-141.
30. Ronald, A., Happe, F., Bolton, P., Butcher, L. M., Price, T. S., Wheelwright, S., Baron-Cohen, S., & Plomin, R. (2006). Genetic heterogeneity between the three components of the autism spectrum: A twin study. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 691-699.
31. Ronald, A., Happe, F., & Plomin, R. (2005). The genetic relationship between individual differences in social and nonsocial behaviours characteristic of autism. Developmental Science, 8, 444-458.
32. Schmitz, S., Cherny, S. S., & Fulker, D. W. (1998). Increase in power through multivariate analyses. Behavior Genetics, 28, 357-363.
33. Smalley, S. L., McCracken, J., & Tanguay, P. (1995). Autism, affective disorders, and social phobia. American Journal of Medical Genetics, 60, 19-26.
34. Spiker, D., Lotspeich, L. J., Dimiceli, S., Myers, R. M., & Risch, N. (2002). Behavioral phenotypic variation in autism multiplex families: Evidence for a continuous severity gradient. American Journal of Medical Genetics, 114, 129-136.
35. Stevens, J. (1996). Multivariate statistics for the social sciences. (3rd ed.) Mahwah, New Jersey: Lawrence Erlbaum Associates, Inc.
36. Sturm, H., Fernell, E., & Gillberg, C. (2004). Autism spectrum disorders in children with normal intellectual levels: Associated impairments and subgroups. Developmental Medicine and Child Neurology, 46, 444-447.
37. Van der Ende, J., & Verhulst, F. C. (2005). Informant, gender and age differences in ratings of adolescent problem behaviour. European Child and Adolescent Psychiatry, 14, 117-126.
38. Verhulst, F. C., Van der Ende, J., & Koot, H. M. (1997). Handleiding voor de Youth Self Report (YSR) [Dutch manual for the YSR]. Rotterdam, the Netherlands: Academic Medical Centre Rotterdam/Erasmus University, Sophia Children's Hospital, Department of Child Psychiatry.
39. Wakabayashi, A., Baron-Cohen, S., Wheelwright, S., & Tojo, Y. (2006). The Autism-Spectrum Quotient (AQ) in Japan: A Cross-Cultural Comparison. Journal of Autism and Developmental Disorders, 36, 263-270.
40. Yoshida, Y. & Uchiyama, T. (2004). The clinical necessity for assessing Attention Deficit/Hyperactivity Disorder (AD/HD) symptoms in children with high-functioning Pervasive Developmental Disorder (PDD). European Child and Adolescent Psychiatry, 13, 307-314.