Evaluation of 23 lots of commercially available cryopreserved hepatocytes for induction assays of human cytochromes p450s

Drug Metabolism and Disposition

Volumn 42, Issue 5, 2014, Pages 867-871

  Yajima, Kanako ^a   Uno, Yasuhiro ^a   Murayama, Norie ^b   Uehara, Shotaro ^a   Shimizu, Makiko ^b   Nakamura, Chika ^a   Iwasaki, Kazuhide ^a   Utoh, Masahiro ^a   Yamazaki, Hiroshi ^b  

^a SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; MESSENGER RNA; OMEPRAZOLE; PHENOBARBITAL; RIFAMPICIN; DRUG;

ARTICLE; CONTROLLED STUDY; CRYOPRESERVATION; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; BIOSYNTHESIS; CELL CULTURE; CULTURE TECHNIQUE; CYTOLOGY; DRUG DEVELOPMENT; DRUG EFFECTS; DRUG INTERACTION; ENZYMOLOGY; METABOLISM;

CELL CULTURE TECHNIQUES; CELLS, CULTURED; CRYOPRESERVATION; CYTOCHROME P-450 ENZYME SYSTEM; DRUG DISCOVERY; DRUG INTERACTIONS; ENZYME INDUCTION; HEPATOCYTES; HUMANS; PHARMACEUTICAL PREPARATIONS; RNA, MESSENGER;

EID: 84898786081     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.056804     Document Type: Article

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