-
1
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
3
-
-
0842321501
-
MicroRNA targets in Drosophila
-
Enright AJ, John B, Gaul U, Tuschl T, Sander C, et al. (2003) MicroRNA targets in Drosophila. Genome Biol 5: R1.
-
(2003)
Genome Biol
, vol.5
-
-
Enright, A.J.1
John, B.2
Gaul, U.3
Tuschl, T.4
Sander, C.5
-
4
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
5
-
-
78049295975
-
MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo
-
Horie T, Ono K, Horiguchi M, Nishi H, Nakamura T, et al. (2010) MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo. Proc Natl Acad Sci U S A 107: 17321-17326.
-
(2010)
Proc Natl Acad Sci U S a
, vol.107
, pp. 17321-17326
-
-
Horie, T.1
Ono, K.2
Horiguchi, M.3
Nishi, H.4
Nakamura, T.5
-
6
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
DOI 10.1172/JCI200215593
-
Horton JD, Goldstein JL, Brown MS (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109: 1125-1131. (Pubitemid 34496588)
-
(2002)
Journal of Clinical Investigation
, vol.109
, Issue.9
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
7
-
-
0034693259
-
Sterol regulatory element-binding proteins (SREBPs): Key regulators of nutritional homeostasis and insulin action
-
Osborne TF (2000) Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action. J Biol Chem 275: 32379-32382.
-
(2000)
J Biol Chem
, vol.275
, pp. 32379-32382
-
-
Osborne, T.F.1
-
8
-
-
77953787211
-
MiR-33 contributes to the regulation of cholesterol homeostasis
-
Rayner KJ, Suarez Y, Davalos A, Parathath S, Fitzgerald ML, et al. (2010) MiR-33 contributes to the regulation of cholesterol homeostasis. Science 328: 1570-1573.
-
(2010)
Science
, vol.328
, pp. 1570-1573
-
-
Rayner, K.J.1
Suarez, Y.2
Davalos, A.3
Parathath, S.4
Fitzgerald, M.L.5
-
9
-
-
77953780835
-
MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis
-
Najafi-Shoushtari SH, Kristo F, Li Y, Shioda T, Cohen DE, et al. (2010) MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science 328: 1566-1569.
-
(2010)
Science
, vol.328
, pp. 1566-1569
-
-
Najafi-Shoushtari, S.H.1
Kristo, F.2
Li, Y.3
Shioda, T.4
Cohen, D.E.5
-
11
-
-
77958553499
-
Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation
-
Gerin I, Clerbaux LA, Haumont O, Lanthier N, Das AK, et al. (2010) Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J Biol Chem 285: 33652-33661.
-
(2010)
J Biol Chem
, vol.285
, pp. 33652-33661
-
-
Gerin, I.1
Clerbaux, L.A.2
Haumont, O.3
Lanthier, N.4
Das, A.K.5
-
12
-
-
84857953621
-
Mir-33 regulates cell proliferation and cell cycle progression
-
Cirera-Salinas D, Pauta M, Allen RM, Salerno AG, Ramirez CM, et al. (2012) Mir-33 regulates cell proliferation and cell cycle progression. Cell Cycle 11: 922-933.
-
(2012)
Cell Cycle
, vol.11
, pp. 922-933
-
-
Cirera-Salinas, D.1
Pauta, M.2
Allen, R.M.3
Salerno, A.G.4
Ramirez, C.M.5
-
13
-
-
79960015327
-
Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
-
Rayner KJ, Sheedy FJ, Esau CC, Hussain FN, Temel RE, et al. (2011) Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. J Clin Invest 121: 2921-2931.
-
(2011)
J Clin Invest
, vol.121
, pp. 2921-2931
-
-
Rayner, K.J.1
Sheedy, F.J.2
Esau, C.C.3
Hussain, F.N.4
Temel, R.E.5
-
14
-
-
79959326172
-
miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling
-
Davalos A, Goedeke L, Smibert P, Ramirez CM, Warrier NP, et al. (2011) miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling. Proc Natl Acad Sci U S A 108: 9232-9237.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 9232-9237
-
-
Davalos, A.1
Goedeke, L.2
Smibert, P.3
Ramirez, C.M.4
Warrier, N.P.5
-
15
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
DOI 10.1126/science.1141634
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, et al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316: 889-894. (Pubitemid 46764279)
-
(2007)
Science
, vol.316
, Issue.5826
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.B.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
Shields, B.11
Harries, L.W.12
Barrett, J.C.13
Ellard, S.14
Groves, C.J.15
Knight, B.16
Patch, A.-M.17
Ness, A.R.18
Ebrahim, S.19
Lawlor, D.A.20
Ring, S.M.21
Ben-Shlomo, Y.22
Jarvelin, M.-R.23
Sovio, U.24
Bennett, A.J.25
Melzer, D.26
Ferrucci, L.27
Loos, R.J.F.28
Barroso, I.29
Wareham, N.J.30
Karpe, F.31
Owen, K.R.32
Cardon, L.R.33
Walker, M.34
Hitman, G.A.35
Palmer, C.N.A.36
Doney, A.S.F.37
Morris, A.D.38
Smith, G.D.39
Hattersley, A.T.40
McCarthy, M.I.41
more..
-
16
-
-
39049154918
-
The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily
-
Sanchez-Pulido L, Andrade-Navarro MA (2007) The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily. BMC Biochem 8: 23.
-
(2007)
BMC Biochem
, vol.8
, pp. 23
-
-
Sanchez-Pulido, L.1
Andrade-Navarro, M.A.2
-
17
-
-
36749041363
-
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
-
DOI 10.1126/science.1151710
-
Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, et al. (2007) The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 318: 1469-1472. (Pubitemid 350208961)
-
(2007)
Science
, vol.318
, Issue.5855
, pp. 1469-1472
-
-
Gerken, T.1
Girard, C.A.2
Tung, Y.-C.L.3
Webby, C.J.4
Saudek, V.5
Hewitson, K.S.6
Yeo, G.S.H.7
McDonough, M.A.8
Cunliffe, S.9
McNeill, L.A.10
Galvanovskis, J.11
Rorsman, P.12
Robins, P.13
Prieur, X.14
Coll, A.P.15
Ma, M.16
Jovanovic, Z.17
Farooqi, I.S.18
Sedgwick, B.19
Barroso, I.20
Lindahl, T.21
Ponting, C.P.22
Ashcroft, F.M.23
O'Rahilly, S.24
Schofield, C.J.25
more..
-
18
-
-
54849381000
-
Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO
-
Jia G, Yang CG, Yang S, Jian X, Yi C, et al. (2008) Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett 582: 3313-3319.
-
(2008)
FEBS Lett
, vol.582
, pp. 3313-3319
-
-
Jia, G.1
Yang, C.G.2
Yang, S.3
Jian, X.4
Yi, C.5
-
19
-
-
77951623073
-
Crystal structure of the FTO protein reveals basis for its substrate specificity
-
Han Z, Niu T, Chang J, Lei X, Zhao M, et al. (2010) Crystal structure of the FTO protein reveals basis for its substrate specificity. Nature 464: 1205-1209.
-
(2010)
Nature
, vol.464
, pp. 1205-1209
-
-
Han, Z.1
Niu, T.2
Chang, J.3
Lei, X.4
Zhao, M.5
-
20
-
-
81355146483
-
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
-
Jia G, Fu Y, Zhao X, Dai Q, Zheng G, et al. (2011) N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol 7: 885-887.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 885-887
-
-
Jia, G.1
Fu, Y.2
Zhao, X.3
Dai, Q.4
Zheng, G.5
-
21
-
-
42249083837
-
The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain
-
DOI 10.1210/en.2007-1457
-
Fredriksson R, Hagglund M, Olszewski PK, Stephansson O, Jacobsson JA, et al. (2008) The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain. Endocrinology 149: 2062-2071. (Pubitemid 351574484)
-
(2008)
Endocrinology
, vol.149
, Issue.5
, pp. 2062-2071
-
-
Fredriksson, R.1
Hagglund, M.2
Olszewski, P.K.3
Stephansson, O.4
Jacobsson, J.A.5
Olszewska, A.M.6
Levine, A.S.7
Lindblom, J.8
Schioth, H.B.9
-
22
-
-
78649459183
-
Overexpression of Fto leads to increased food intake and results in obesity
-
Church C, Moir L, McMurray F, Girard C, Banks GT, et al. (2010) Overexpression of Fto leads to increased food intake and results in obesity. Nat Genet 42: 1086-1092.
-
(2010)
Nat Genet
, vol.42
, pp. 1086-1092
-
-
Church, C.1
Moir, L.2
McMurray, F.3
Girard, C.4
Banks, G.T.5
-
23
-
-
70149100469
-
A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene
-
Church C, Lee S, Bagg EA, McTaggart JS, Deacon R, et al. (2009) A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene. PLoS Genet 5: e1000599.
-
(2009)
PLoS Genet
, vol.5
-
-
Church, C.1
Lee, S.2
Bagg, E.A.3
McTaggart, J.S.4
Deacon, R.5
-
24
-
-
0027191838
-
Lipogenic enzyme and apoprotein messenger RNAs in long-term primary culture of chicken hepatocytes
-
Douaire M, Belloir B, Guillemot JC, Fraslin JM, Langlois P, et al. (1993) Lipogenic enzyme and apoprotein messenger RNAs in long-term primary culture of chicken hepatocytes. J Cell Sci 104 (Pt 3): 713-718. (Pubitemid 23123464)
-
(1993)
Journal of Cell Science
, vol.104
, Issue.3
, pp. 713-718
-
-
Douaire, M.1
Belloir, B.2
Guillemot, J.-C.3
Fraslin, J.-M.4
Langlois, P.5
Mallard, J.6
-
25
-
-
84879157260
-
MicroRNA-126 expression is decreased in cultured primary chicken hepatocytes and targets the sprouty-related EVH1 domain containing 1 mRNA
-
Wang XG, Shao F, Wang HJ, Yang L, Yu JF, et al. (2013) MicroRNA-126 expression is decreased in cultured primary chicken hepatocytes and targets the sprouty-related EVH1 domain containing 1 mRNA. Poult Sci 92: 1888-1896.
-
(2013)
Poult Sci
, vol.92
, pp. 1888-1896
-
-
Wang, X.G.1
Shao, F.2
Wang, H.J.3
Yang, L.4
Yu, J.F.5
-
26
-
-
67349211789
-
Inactivation of the Fto gene protects from obesity
-
Fischer J, Koch L, Emmerling C, Vierkotten J, Peters T, et al. (2009) Inactivation of the Fto gene protects from obesity. Nature 458: 894-898.
-
(2009)
Nature
, vol.458
, pp. 894-898
-
-
Fischer, J.1
Koch, L.2
Emmerling, C.3
Vierkotten, J.4
Peters, T.5
-
27
-
-
77957277779
-
Relationship between blood glucose levels and hepatic Fto mRNA expression in mice
-
Poritsanos NJ, Lew PS, Mizuno TM (2010) Relationship between blood glucose levels and hepatic Fto mRNA expression in mice. Biochem Biophys Res Commun 400: 713-717.
-
(2010)
Biochem Biophys Res Commun
, vol.400
, pp. 713-717
-
-
Poritsanos, N.J.1
Lew, P.S.2
Mizuno, T.M.3
-
28
-
-
0030968879
-
Lipoprotein metabolism and fattening in poultry
-
Hermier D (1997) Lipoprotein metabolism and fattening in poultry. J Nutr 127: 805S-808S.
-
(1997)
J Nutr
, vol.127
-
-
Hermier, D.1
-
29
-
-
0035955361
-
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
-
DOI 10.1126/science.1065062
-
Lau NC, Lim LP, Weinstein EG, Bartel DP (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294: 858-862. (Pubitemid 33032104)
-
(2001)
Science
, vol.294
, Issue.5543
, pp. 858-862
-
-
Lau, N.C.1
Lim, L.P.2
Weinstein, E.G.3
Bartel, D.P.4
-
30
-
-
6344281172
-
Identification of mammalian microRNA host genes and transcription units
-
DOI 10.1101/gr.2722704
-
Rodriguez A, Griffiths-Jones S, Ashurst JL, Bradley A (2004) Identification of mammalian microRNA host genes and transcription units. Genome Res 14: 1902-1910. (Pubitemid 39386503)
-
(2004)
Genome Research
, vol.14
, Issue.10 A
, pp. 1902-1910
-
-
Rodriguez, A.1
Griffiths-Jones, S.2
Ashurst, J.L.3
Bradley, A.4
-
31
-
-
84887212400
-
Cepred: Predicting the co-expression patterns of the human intronic microRNAs with their host genes
-
Wang D, Lu M, Miao J, Li T, Wang E, et al. (2009) Cepred: predicting the co-expression patterns of the human intronic microRNAs with their host genes. PLoS One 4: e4421.
-
(2009)
PLoS One
, vol.4
-
-
Wang, D.1
Lu, M.2
Miao, J.3
Li, T.4
Wang, E.5
-
32
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
-
Lewis BP, Burge CB, Bartel DP (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20. (Pubitemid 40094598)
-
(2005)
Cell
, vol.120
, Issue.1
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
33
-
-
20944450160
-
Combinatorial microRNA target predictions
-
DOI 10.1038/ng1536
-
Krek A, Grun D, Poy MN, Wolf R, Rosenberg L, et al. (2005) Combinatorial microRNA target predictions. Nat Genet 37: 495-500. (Pubitemid 40617277)
-
(2005)
Nature Genetics
, vol.37
, Issue.5
, pp. 495-500
-
-
Krek, A.1
Grun, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
Epstein, E.J.6
MacMenamin, P.7
Da, P.I.8
Gunsalus, K.C.9
Stoffel, M.10
Rajewsky, N.11
-
34
-
-
84864707357
-
Variation in sequence and expression of the avian FTO, and association with glucose metabolism, body weight, fatness and body composition in chickens
-
Lond
-
Jia X, Nie Q, Lamont SJ, Zhang X (2012) Variation in sequence and expression of the avian FTO, and association with glucose metabolism, body weight, fatness and body composition in chickens. Int J Obes (Lond) 36: 1054-1061.
-
(2012)
Int J Obes
, vol.36
, pp. 1054-1061
-
-
Jia, X.1
Nie, Q.2
Lamont, S.J.3
Zhang, X.4
-
35
-
-
84866406290
-
Chicken FTO gene: Tissue-specific expression, brain distribution, breed difference and effect of fasting
-
Wang Y, Rao K, Yuan L, Everaert N, Buyse J, et al. (2012) Chicken FTO gene: tissue-specific expression, brain distribution, breed difference and effect of fasting. Comp Biochem Physiol A Mol Integr Physiol 163: 246-252.
-
(2012)
Comp Biochem Physiol A Mol Integr Physiol
, vol.163
, pp. 246-252
-
-
Wang, Y.1
Rao, K.2
Yuan, L.3
Everaert, N.4
Buyse, J.5
-
36
-
-
78649512744
-
The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice
-
Gao X, Shin YH, Li M, Wang F, Tong Q, et al. (2010) The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PLoS One 5: e14005.
-
(2010)
PLoS One
, vol.5
-
-
Gao, X.1
Shin, Y.H.2
Li, M.3
Wang, F.4
Tong, Q.5
-
37
-
-
83355169589
-
Cloning and characterization of chicken fat mass and obesity associated (Fto) gene: Fasting affects Fto expression
-
Tiwari A, Krzysik-Walker SM, Ramachandran R (2012) Cloning and characterization of chicken fat mass and obesity associated (Fto) gene: fasting affects Fto expression. Domest Anim Endocrinol 42: 1-10.
-
(2012)
Domest Anim Endocrinol
, vol.42
, pp. 1-10
-
-
Tiwari, A.1
Krzysik-Walker, S.M.2
Ramachandran, R.3
|