-
1
-
-
84874262984
-
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
-
Arnold E.S., Ling S.C., Huelga S.C., Lagier-Tourenne C., Polymenidou M., Ditsworth D., Kordasiewicz H.B., McAlonis-Downes M., Platoshyn O., Parone P.A., et al. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proc. Natl. Acad. Sci. USA 2013, 110:E736-E745.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
-
-
Arnold, E.S.1
Ling, S.C.2
Huelga, S.C.3
Lagier-Tourenne, C.4
Polymenidou, M.5
Ditsworth, D.6
Kordasiewicz, H.B.7
McAlonis-Downes, M.8
Platoshyn, O.9
Parone, P.A.10
-
2
-
-
2642526164
-
VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
-
Azzouz M., Ralph G.S., Storkebaum E., Walmsley L.E., Mitrophanous K.A., Kingsman S.M., Carmeliet P., Mazarakis N.D. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 2004, 429:413-417.
-
(2004)
Nature
, vol.429
, pp. 413-417
-
-
Azzouz, M.1
Ralph, G.S.2
Storkebaum, E.3
Walmsley, L.E.4
Mitrophanous, K.A.5
Kingsman, S.M.6
Carmeliet, P.7
Mazarakis, N.D.8
-
3
-
-
84879088376
-
Motor neuron involvement in multisystem proteinopathy: implications for ALS
-
Benatar M., Wuu J., Fernandez C., Weihl C.C., Katzen H., Steele J., Oskarsson B., Taylor J.P. Motor neuron involvement in multisystem proteinopathy: implications for ALS. Neurology 2013, 80:1874-1880.
-
(2013)
Neurology
, vol.80
, pp. 1874-1880
-
-
Benatar, M.1
Wuu, J.2
Fernandez, C.3
Weihl, C.C.4
Katzen, H.5
Steele, J.6
Oskarsson, B.7
Taylor, J.P.8
-
4
-
-
33744798774
-
Onset and progression in inherited ALS determined by motor neurons and microglia
-
Boillée S., Yamanaka K., Lobsiger C.S., Copeland N.G., Jenkins N.A., Kassiotis G., Kollias G., Cleveland D.W. Onset and progression in inherited ALS determined by motor neurons and microglia. Science 2006, 312:1389-1392.
-
(2006)
Science
, vol.312
, pp. 1389-1392
-
-
Boillée, S.1
Yamanaka, K.2
Lobsiger, C.S.3
Copeland, N.G.4
Jenkins, N.A.5
Kassiotis, G.6
Kollias, G.7
Cleveland, D.W.8
-
5
-
-
79954534432
-
Increased IGF-1 in muscle modulates the phenotype of severe SMA mice
-
Bosch-Marcé M., Wee C.D., Martinez T.L., Lipkes C.E., Choe D.W., Kong L., Van Meerbeke J.P., Musarò A., Sumner C.J. Increased IGF-1 in muscle modulates the phenotype of severe SMA mice. Hum. Mol. Genet. 2011, 20:1844-1853.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1844-1853
-
-
Bosch-Marcé, M.1
Wee, C.D.2
Martinez, T.L.3
Lipkes, C.E.4
Choe, D.W.5
Kong, L.6
Van Meerbeke, J.P.7
Musarò, A.8
Sumner, C.J.9
-
6
-
-
0027476102
-
Quantitative analysis of the human alpha-skeletal actin gene in transgenic mice
-
Brennan K.J., Hardeman E.C. Quantitative analysis of the human alpha-skeletal actin gene in transgenic mice. J.Biol. Chem. 1993, 268:719-725.
-
(1993)
J.Biol. Chem.
, vol.268
, pp. 719-725
-
-
Brennan, K.J.1
Hardeman, E.C.2
-
7
-
-
84861234054
-
Neurogenic and myogenic contributions to hereditary motor neuron disease
-
Bricceno K.V., Fischbeck K.H., Burnett B.G. Neurogenic and myogenic contributions to hereditary motor neuron disease. Neurodegener. Dis. 2012, 9:199-209.
-
(2012)
Neurodegener. Dis.
, vol.9
, pp. 199-209
-
-
Bricceno, K.V.1
Fischbeck, K.H.2
Burnett, B.G.3
-
8
-
-
0035809926
-
Deletion of murine SMN exon 7 directed to skeletal muscle leads to severe muscular dystrophy
-
Cifuentes-Diaz C., Frugier T., Tiziano F.D., Lacène E., Roblot N., Joshi V., Moreau M.H., Melki J. Deletion of murine SMN exon 7 directed to skeletal muscle leads to severe muscular dystrophy. J.Cell Biol. 2001, 152:1107-1114.
-
(2001)
J.Cell Biol.
, vol.152
, pp. 1107-1114
-
-
Cifuentes-Diaz, C.1
Frugier, T.2
Tiziano, F.D.3
Lacène, E.4
Roblot, N.5
Joshi, V.6
Moreau, M.H.7
Melki, J.8
-
9
-
-
0141642203
-
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
-
Clement A.M., Nguyen M.D., Roberts E.A., Garcia M.L., Boillée S., Rule M., McMahon A.P., Doucette W., Siwek D., Ferrante R.J., et al. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science 2003, 302:113-117.
-
(2003)
Science
, vol.302
, pp. 113-117
-
-
Clement, A.M.1
Nguyen, M.D.2
Roberts, E.A.3
Garcia, M.L.4
Boillée, S.5
Rule, M.6
McMahon, A.P.7
Doucette, W.8
Siwek, D.9
Ferrante, R.J.10
-
10
-
-
33749010065
-
Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport
-
Custer S.K., Garden G.A., Gill N., Rueb U., Libby R.T., Schultz C., Guyenet S.J., Deller T., Westrum L.E., Sopher B.L., La Spada A.R. Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport. Nat. Neurosci. 2006, 9:1302-1311.
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 1302-1311
-
-
Custer, S.K.1
Garden, G.A.2
Gill, N.3
Rueb, U.4
Libby, R.T.5
Schultz, C.6
Guyenet, S.J.7
Deller, T.8
Westrum, L.E.9
Sopher, B.L.10
La Spada, A.R.11
-
11
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
-
DeJesus-Hernandez M., Mackenzie I.R., Boeve B.F., Boxer A.L., Baker M., Rutherford N.J., Nicholson A.M., Finch N.A., Flynn H., Adamson J., et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011, 72:245-256.
-
(2011)
Neuron
, vol.72
, pp. 245-256
-
-
DeJesus-Hernandez, M.1
Mackenzie, I.R.2
Boeve, B.F.3
Boxer, A.L.4
Baker, M.5
Rutherford, N.J.6
Nicholson, A.M.7
Finch, N.A.8
Flynn, H.9
Adamson, J.10
-
12
-
-
13844253540
-
Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model
-
Dobrowolny G., Giacinti C., Pelosi L., Nicoletti C., Winn N., Barberi L., Molinaro M., Rosenthal N., Musarò A. Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model. J.Cell Biol. 2005, 168:193-199.
-
(2005)
J.Cell Biol.
, vol.168
, pp. 193-199
-
-
Dobrowolny, G.1
Giacinti, C.2
Pelosi, L.3
Nicoletti, C.4
Winn, N.5
Barberi, L.6
Molinaro, M.7
Rosenthal, N.8
Musarò, A.9
-
13
-
-
54849404282
-
Skeletal muscle is a primary target of SOD1G93A-mediated toxicity
-
Dobrowolny G., Aucello M., Rizzuto E., Beccafico S., Mammucari C., Boncompagni S., Belia S., Wannenes F., Nicoletti C., Del Prete Z., et al. Skeletal muscle is a primary target of SOD1G93A-mediated toxicity. Cell Metab. 2008, 8:425-436.
-
(2008)
Cell Metab.
, vol.8
, pp. 425-436
-
-
Dobrowolny, G.1
Aucello, M.2
Rizzuto, E.3
Beccafico, S.4
Mammucari, C.5
Boncompagni, S.6
Belia, S.7
Wannenes, F.8
Nicoletti, C.9
Del Prete, Z.10
-
14
-
-
77953356748
-
Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: roles in skeletal muscle growth and differentiation
-
Duan C., Ren H., Gao S. Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: roles in skeletal muscle growth and differentiation. Gen. Comp. Endocrinol. 2010, 167:344-351.
-
(2010)
Gen. Comp. Endocrinol.
, vol.167
, pp. 344-351
-
-
Duan, C.1
Ren, H.2
Gao, S.3
-
16
-
-
0029024336
-
Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons
-
Funakoshi H., Belluardo N., Arenas E., Yamamoto Y., Casabona A., Persson H., Ibáñez C.F. Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. Science 1995, 268:1495-1499.
-
(1995)
Science
, vol.268
, pp. 1495-1499
-
-
Funakoshi, H.1
Belluardo, N.2
Arenas, E.3
Yamamoto, Y.4
Casabona, A.5
Persson, H.6
Ibáñez, C.F.7
-
17
-
-
84858017006
-
Intercellular (mis)communication in neurodegenerative disease
-
Garden G.A., La Spada A.R. Intercellular (mis)communication in neurodegenerative disease. Neuron 2012, 73:886-901.
-
(2012)
Neuron
, vol.73
, pp. 886-901
-
-
Garden, G.A.1
La Spada, A.R.2
-
18
-
-
0037096365
-
Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous Purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice
-
Garden G.A., Libby R.T., Fu Y.H., Kinoshita Y., Huang J., Possin D.E., Smith A.C., Martinez R.A., Fine G.C., Grote S.K., et al. Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous Purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice. J.Neurosci. 2002, 22:4897-4905.
-
(2002)
J.Neurosci.
, vol.22
, pp. 4897-4905
-
-
Garden, G.A.1
Libby, R.T.2
Fu, Y.H.3
Kinoshita, Y.4
Huang, J.5
Possin, D.E.6
Smith, A.C.7
Martinez, R.A.8
Fine, G.C.9
Grote, S.K.10
-
19
-
-
80053902729
-
Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
-
Hua Y., Sahashi K., Rigo F., Hung G., Horev G., Bennett C.F., Krainer A.R. Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model. Nature 2011, 478:123-126.
-
(2011)
Nature
, vol.478
, pp. 123-126
-
-
Hua, Y.1
Sahashi, K.2
Rigo, F.3
Hung, G.4
Horev, G.5
Bennett, C.F.6
Krainer, A.R.7
-
20
-
-
74049164709
-
Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
-
Ilieva H., Polymenidou M., Cleveland D.W. Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond. J.Cell Biol. 2009, 187:761-772.
-
(2009)
J.Cell Biol.
, vol.187
, pp. 761-772
-
-
Ilieva, H.1
Polymenidou, M.2
Cleveland, D.W.3
-
21
-
-
62149127399
-
Recovery of function in a myogenic mouse model of spinal bulbar muscular atrophy
-
Johansen J.A., Yu Z., Mo K., Monks D.A., Lieberman A.P., Breedlove S.M., Jordan C.L. Recovery of function in a myogenic mouse model of spinal bulbar muscular atrophy. Neurobiol. Dis. 2009, 34:113-120.
-
(2009)
Neurobiol. Dis.
, vol.34
, pp. 113-120
-
-
Johansen, J.A.1
Yu, Z.2
Mo, K.3
Monks, D.A.4
Lieberman, A.P.5
Breedlove, S.M.6
Jordan, C.L.7
-
22
-
-
84876900163
-
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
-
Kang S.H., Li Y., Fukaya M., Lorenzini I., Cleveland D.W., Ostrow L.W., Rothstein J.D., Bergles D.E. Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nat. Neurosci. 2013, 16:571-579.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 571-579
-
-
Kang, S.H.1
Li, Y.2
Fukaya, M.3
Lorenzini, I.4
Cleveland, D.W.5
Ostrow, L.W.6
Rothstein, J.D.7
Bergles, D.E.8
-
23
-
-
77951520909
-
Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy
-
Katsuno M., Adachi H., Minamiyama M., Waza M., Doi H., Kondo N., Mizoguchi H., Nitta A., Yamada K., Banno H., et al. Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy. J.Neurosci. 2010, 30:5702-5712.
-
(2010)
J.Neurosci.
, vol.30
, pp. 5702-5712
-
-
Katsuno, M.1
Adachi, H.2
Minamiyama, M.3
Waza, M.4
Doi, H.5
Kondo, N.6
Mizoguchi, H.7
Nitta, A.8
Yamada, K.9
Banno, H.10
-
24
-
-
84869870525
-
Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA)
-
Katsuno M., Tanaka F., Adachi H., Banno H., Suzuki K., Watanabe H., Sobue G. Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA). Prog. Neurobiol. 2012, 99:246-256.
-
(2012)
Prog. Neurobiol.
, vol.99
, pp. 246-256
-
-
Katsuno, M.1
Tanaka, F.2
Adachi, H.3
Banno, H.4
Suzuki, K.5
Watanabe, H.6
Sobue, G.7
-
25
-
-
61949206262
-
Getting a handle on Huntington's disease: silencing neurodegeneration
-
La Spada A.R. Getting a handle on Huntington's disease: silencing neurodegeneration. Nat. Med. 2009, 15:252-253.
-
(2009)
Nat. Med.
, vol.15
, pp. 252-253
-
-
La Spada, A.R.1
-
26
-
-
77949775195
-
Repeat expansion disease: progress and puzzles in disease pathogenesis
-
La Spada A.R., Taylor J.P. Repeat expansion disease: progress and puzzles in disease pathogenesis. Nat. Rev. Genet. 2010, 11:247-258.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 247-258
-
-
La Spada, A.R.1
Taylor, J.P.2
-
27
-
-
0025800526
-
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
-
La Spada A.R., Wilson E.M., Lubahn D.B., Harding A.E., Fischbeck K.H. Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 1991, 352:77-79.
-
(1991)
Nature
, vol.352
, pp. 77-79
-
-
La Spada, A.R.1
Wilson, E.M.2
Lubahn, D.B.3
Harding, A.E.4
Fischbeck, K.H.5
-
28
-
-
0028797783
-
Identification and characterization of a spinal muscular atrophy-determining gene
-
Lefebvre S., Bürglen L., Reboullet S., Clermont O., Burlet P., Viollet L., Benichou B., Cruaud C., Millasseau P., Zeviani M., et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell 1995, 80:155-165.
-
(1995)
Cell
, vol.80
, pp. 155-165
-
-
Lefebvre, S.1
Bürglen, L.2
Reboullet, S.3
Clermont, O.4
Burlet, P.5
Viollet, L.6
Benichou, B.7
Cruaud, C.8
Millasseau, P.9
Zeviani, M.10
-
29
-
-
84899918530
-
Peripheral androgen receptor gene suppression rescues disease inmouse models of spinal and bulbar muscular atrophy
-
Published online April 16, 2014
-
Lieberman A., Yu Z., Murray S., Peralta R., Low A., Shuling G., Yu X.X., Cortes C.J., Bennett C.F., Monia B.P., La Spada A.R., Hung G. Peripheral androgen receptor gene suppression rescues disease inmouse models of spinal and bulbar muscular atrophy. Cell Rep 2014, 7. Published online April 16, 2014. 10.1016/j.celrep.2014.02.008.
-
(2014)
Cell Rep
, vol.7
-
-
Lieberman, A.1
Yu, Z.2
Murray, S.3
Peralta, R.4
Low, A.5
Shuling, G.6
Yu, X.X.7
Cortes, C.J.8
Bennett, C.F.9
Monia, B.P.10
La Spada, A.R.11
Hung, G.12
-
30
-
-
0037096354
-
Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease
-
Lino M.M., Schneider C., Caroni P. Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease. J.Neurosci. 2002, 22:4825-4832.
-
(2002)
J.Neurosci.
, vol.22
, pp. 4825-4832
-
-
Lino, M.M.1
Schneider, C.2
Caroni, P.3
-
31
-
-
0028834086
-
Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization
-
Livak K.J., Flood S.J., Marmaro J., Giusti W., Deetz K. Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. PCR Methods Appl. 1995, 4:357-362.
-
(1995)
PCR Methods Appl.
, vol.4
, pp. 357-362
-
-
Livak, K.J.1
Flood, S.J.2
Marmaro, J.3
Giusti, W.4
Deetz, K.5
-
32
-
-
84862883258
-
Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy
-
Martinez T.L., Kong L., Wang X., Osborne M.A., Crowder M.E., Van Meerbeke J.P., Xu X., Davis C., Wooley J., Goldhamer D.J., et al. Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy. J.Neurosci. 2012, 32:8703-8715.
-
(2012)
J.Neurosci.
, vol.32
, pp. 8703-8715
-
-
Martinez, T.L.1
Kong, L.2
Wang, X.3
Osborne, M.A.4
Crowder, M.E.5
Van Meerbeke, J.P.6
Xu, X.7
Davis, C.8
Wooley, J.9
Goldhamer, D.J.10
-
33
-
-
33845876647
-
Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis
-
Miller T.M., Kim S.H., Yamanaka K., Hester M., Umapathi P., Arnson H., Rizo L., Mendell J.R., Gage F.H., Cleveland D.W., Kaspar B.K. Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA 2006, 103:19546-19551.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 19546-19551
-
-
Miller, T.M.1
Kim, S.H.2
Yamanaka, K.3
Hester, M.4
Umapathi, P.5
Arnson, H.6
Rizo, L.7
Mendell, J.R.8
Gage, F.H.9
Cleveland, D.W.10
Kaspar, B.K.11
-
34
-
-
0033210772
-
Gene targeting restricted to mouse striated muscle lineage
-
Miniou P., Tiziano D., Frugier T., Roblot N., Le Meur M., Melki J. Gene targeting restricted to mouse striated muscle lineage. Nucleic Acids Res. 1999, 27:e27.
-
(1999)
Nucleic Acids Res.
, vol.27
-
-
Miniou, P.1
Tiziano, D.2
Frugier, T.3
Roblot, N.4
Le Meur, M.5
Melki, J.6
-
35
-
-
36248935287
-
Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression
-
Mochel F., Charles P., Seguin F., Barritault J., Coussieu C., Perin L., Le Bouc Y., Gervais C., Carcelain G., Vassault A., et al. Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression. PLoS ONE 2007, 2:e647.
-
(2007)
PLoS ONE
, vol.2
-
-
Mochel, F.1
Charles, P.2
Seguin, F.3
Barritault, J.4
Coussieu, C.5
Perin, L.6
Le Bouc, Y.7
Gervais, C.8
Carcelain, G.9
Vassault, A.10
-
36
-
-
36749043765
-
Overexpression of wild-type androgen receptor in muscle recapitulates polyglutamine disease
-
Monks D.A., Johansen J.A., Mo K., Rao P., Eagleson B., Yu Z., Lieberman A.P., Breedlove S.M., Jordan C.L. Overexpression of wild-type androgen receptor in muscle recapitulates polyglutamine disease. Proc. Natl. Acad. Sci. USA 2007, 104:18259-18264.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 18259-18264
-
-
Monks, D.A.1
Johansen, J.A.2
Mo, K.3
Rao, P.4
Eagleson, B.5
Yu, Z.6
Lieberman, A.P.7
Breedlove, S.M.8
Jordan, C.L.9
-
37
-
-
41149113045
-
Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy
-
Murray L.M., Comley L.H., Thomson D., Parkinson N., Talbot K., Gillingwater T.H. Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy. Hum. Mol. Genet. 2008, 17:949-962.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 949-962
-
-
Murray, L.M.1
Comley, L.H.2
Thomson, D.3
Parkinson, N.4
Talbot, K.5
Gillingwater, T.H.6
-
38
-
-
80054880080
-
Reversible molecular pathology of skeletal muscle in spinal muscular atrophy
-
Mutsaers C.A., Wishart T.M., Lamont D.J., Riessland M., Schreml J., Comley L.H., Murray L.M., Parson S.H., Lochmüller H., Wirth B., et al. Reversible molecular pathology of skeletal muscle in spinal muscular atrophy. Hum. Mol. Genet. 2011, 20:4334-4344.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 4334-4344
-
-
Mutsaers, C.A.1
Wishart, T.M.2
Lamont, D.J.3
Riessland, M.4
Schreml, J.5
Comley, L.H.6
Murray, L.M.7
Parson, S.H.8
Lochmüller, H.9
Wirth, B.10
-
39
-
-
68149180778
-
Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy
-
Palazzolo I., Stack C., Kong L., Musaro A., Adachi H., Katsuno M., Sobue G., Taylor J.P., Sumner C.J., Fischbeck K.H., Pennuto M. Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy. Neuron 2009, 63:316-328.
-
(2009)
Neuron
, vol.63
, pp. 316-328
-
-
Palazzolo, I.1
Stack, C.2
Kong, L.3
Musaro, A.4
Adachi, H.5
Katsuno, M.6
Sobue, G.7
Taylor, J.P.8
Sumner, C.J.9
Fischbeck, K.H.10
Pennuto, M.11
-
40
-
-
0035873076
-
Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment
-
Pramatarova A., Laganière J., Roussel J., Brisebois K., Rouleau G.A. Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. J.Neurosci. 2001, 21:3369-3374.
-
(2001)
J.Neurosci.
, vol.21
, pp. 3369-3374
-
-
Pramatarova, A.1
Laganière, J.2
Roussel, J.3
Brisebois, K.4
Rouleau, G.A.5
-
41
-
-
80054837386
-
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
-
ITALSGEN Consortium
-
Renton A.E., Majounie E., Waite A., Simón-Sánchez J., Rollinson S., Gibbs J.R., Schymick J.C., Laaksovirta H., van Swieten J.C., Myllykangas L., et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 2011, 72:257-268. ITALSGEN Consortium.
-
(2011)
Neuron
, vol.72
, pp. 257-268
-
-
Renton, A.E.1
Majounie, E.2
Waite, A.3
Simón-Sánchez, J.4
Rollinson, S.5
Gibbs, J.R.6
Schymick, J.C.7
Laaksovirta, H.8
van Swieten, J.C.9
Myllykangas, L.10
-
42
-
-
33645239157
-
Efficient recombination-based methods for bacterial artificial chromosome fusion and mutagenesis
-
Sopher B.L., La Spada A.R. Efficient recombination-based methods for bacterial artificial chromosome fusion and mutagenesis. Gene 2006, 371:136-143.
-
(2006)
Gene
, vol.371
, pp. 136-143
-
-
Sopher, B.L.1
La Spada, A.R.2
-
43
-
-
12144286872
-
Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration
-
Sopher B.L., Thomas P.S., LaFevre-Bernt M.A., Holm I.E., Wilke S.A., Ware C.B., Jin L.W., Libby R.T., Ellerby L.M., La Spada A.R. Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration. Neuron 2004, 41:687-699.
-
(2004)
Neuron
, vol.41
, pp. 687-699
-
-
Sopher, B.L.1
Thomas, P.S.2
LaFevre-Bernt, M.A.3
Holm, I.E.4
Wilke, S.A.5
Ware, C.B.6
Jin, L.W.7
Libby, R.T.8
Ellerby, L.M.9
La Spada, A.R.10
-
44
-
-
36549087642
-
Spinal and bulbar muscular atrophy: skeletal muscle pathology in male patients and heterozygous females
-
Sorarù G., D'Ascenzo C., Polo A., Palmieri A., Baggio L., Vergani L., Gellera C., Moretto G., Pegoraro E., Angelini C. Spinal and bulbar muscular atrophy: skeletal muscle pathology in male patients and heterozygous females. J.Neurol. Sci. 2008, 264:100-105.
-
(2008)
J.Neurol. Sci.
, vol.264
, pp. 100-105
-
-
Sorarù, G.1
D'Ascenzo, C.2
Polo, A.3
Palmieri, A.4
Baggio, L.5
Vergani, L.6
Gellera, C.7
Moretto, G.8
Pegoraro, E.9
Angelini, C.10
-
45
-
-
84875877357
-
Skeletal muscle degenerative diseases and strategies for therapeutic muscle repair
-
Tabebordbar M., Wang E.T., Wagers A.J. Skeletal muscle degenerative diseases and strategies for therapeutic muscle repair. Annu. Rev. Pathol. 2013, 8:441-475.
-
(2013)
Annu. Rev. Pathol.
, vol.8
, pp. 441-475
-
-
Tabebordbar, M.1
Wang, E.T.2
Wagers, A.J.3
-
46
-
-
84863992416
-
Endocrine prevention and treatment of prostate cancer
-
Tammela T.L. Endocrine prevention and treatment of prostate cancer. Mol. Cell. Endocrinol. 2012, 360:59-67.
-
(2012)
Mol. Cell. Endocrinol.
, vol.360
, pp. 59-67
-
-
Tammela, T.L.1
-
47
-
-
44349169012
-
Systemic AAV6 delivery mediating RNA interference against SOD1: neuromuscular transduction does not alter disease progression in fALS mice
-
Towne C., Raoul C., Schneider B.L., Aebischer P. Systemic AAV6 delivery mediating RNA interference against SOD1: neuromuscular transduction does not alter disease progression in fALS mice. Mol. Ther. 2008, 16:1018-1025.
-
(2008)
Mol. Ther.
, vol.16
, pp. 1018-1025
-
-
Towne, C.1
Raoul, C.2
Schneider, B.L.3
Aebischer, P.4
-
48
-
-
0024781476
-
Lewy bodies in the enteric nervous system in Parkinson's disease
-
Wakabayashi K., Takahashi H., Takeda S., Ohama E., Ikuta F. Lewy bodies in the enteric nervous system in Parkinson's disease. Arch. Histol. Cytol. 1989, 52(Suppl):191-194.
-
(1989)
Arch. Histol. Cytol.
, vol.52
, Issue.SUPPL
, pp. 191-194
-
-
Wakabayashi, K.1
Takahashi, H.2
Takeda, S.3
Ohama, E.4
Ikuta, F.5
-
49
-
-
39749188753
-
Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
-
Yamanaka K., Chun S.J., Boillee S., Fujimori-Tonou N., Yamashita H., Gutmann D.H., Takahashi R., Misawa H., Cleveland D.W. Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nat. Neurosci. 2008, 11:251-253.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 251-253
-
-
Yamanaka, K.1
Chun, S.J.2
Boillee, S.3
Fujimori-Tonou, N.4
Yamashita, H.5
Gutmann, D.H.6
Takahashi, R.7
Misawa, H.8
Cleveland, D.W.9
-
50
-
-
33749442673
-
Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model
-
Yu Z., Dadgar N., Albertelli M., Gruis K., Jordan C., Robins D.M., Lieberman A.P. Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model. J.Clin. Invest. 2006, 116:2663-2672.
-
(2006)
J.Clin. Invest.
, vol.116
, pp. 2663-2672
-
-
Yu, Z.1
Dadgar, N.2
Albertelli, M.3
Gruis, K.4
Jordan, C.5
Robins, D.M.6
Lieberman, A.P.7
|